Guest guest Posted June 11, 2004 Report Share Posted June 11, 2004 Hello Everyone, this is in response to questions about feeling tired all the time, and can you take something for it. I take 20mgmethotrexate a week and just began an Enbrel regimen two weeks ago. My rheumy prescribed Leucovorin (not positive about the spelling) when i told him I was beat all the time. I take 1 tablet the day after I take my MTX dose. He said it is a prescription strength type of vitamin and does not have side effects. ly I haven't done any research on it, but it does seem to help. I take my MTX on Sunday mornings and the Leucovorin on Monday. I noticed that I don't have the inclination to fall asleep at 8 pm like I used to. I still get tired, but much less so. I also take folic acid every day. Rheumy says the primary reason for that is to protect the liver. I take vitamin E, vitamin B complex (stress formula), Calcium plus D and Glucosamine condroitin. Like I said I get tired, but less so. The only time I really feel like a dishrag in the morning is when I've taken a muscle relaxer the night before. That makes me a walking zombie and so I cannot take it during the day. Hope this helps, In peace, e Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 11, 2004 Report Share Posted June 11, 2004 THis is what I found: http://www.aegis.com/factshts/network/access/drugs/leuc.html Drug description Leucovorin is the active form of the B complex vitamin, folate. Leucovorin is used as an antidote to drugs that decrease levels of folic acid. Folic acid helps red and white blood cell formulation and the synthesis of hemoglobin. Some treatments require what is called leucovorin rescue, because the drug used to treat the cancer or other infection has had an adverse effect on folic acid levels. Leucovorin is used to reduce anemia in people taking dapsone, a preventive treatment for PCP. Leucovorin is also taken to decrease the bone marrow toxicity of sulfa drugs, and in combination with pyrimethamine to decrease the toxicity of toxoplasmosis treatment. Leucovorin is used in combination with trimetrexate to prevent bone marrow toxicity. Leucovorin is also used in combination with chemotherapy such as methotrexate. I would add to make sure your vitamin E is d-alpha and not dl-alpha. The synthetic doesn't work nearly as well. in Va. Hello Everyone, this is in response to questions about feeling tired all the time, and can you take something for it. I take 20mgmethotrexate a week and just began an Enbrel regimen two weeks ago. My rheumy prescribed Leucovorin (not positive about the spelling) when i told him I was beat all the time. I take 1 tablet the day after I take my MTX dose. He said it is a prescription strength type of vitamin and does not have side effects. ly I haven't done any research on it, but it does seem to help. I take my MTX on Sunday mornings and the Leucovorin on Monday. I noticed that I don't have the inclination to fall asleep at 8 pm like I used to. I still get tired, but much less so. I also take folic acid every day. Rheumy says the primary reason for that is to protect the liver. I take vitamin E, vitamin B complex (stress formula), Calcium plus D and Glucosamine condroitin. Like I said I get tired, but less so. The only time I really feel like a dishrag in the morning is when I've taken a muscle relaxer the night before. That makes me a walking zombie and so I cannot take it during the day. Hope this helps, In peace, e Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2010 Report Share Posted February 16, 2010 The Real Reason You're Tired -- Your Adrenals Could Be Worn Out You’re exhausted and you really need a good night’s rest... but what if you always feel that way and sleep doesn’t help? A common and often misunderstood cause of constant fatigue is a condition called adrenal fatigue, which regular Daily Health News contributor Mark Stengler, NMD, says he sees in approximately 40% of his patients and which affects as many as 20% of Americans, at least to some degree. However, since few medical doctors recognize and treat adrenal fatigue, millions of people live with feeling chronically exhausted and confused about why that’s so. What makes this particularly disturbing is that once adrenal fatigue is diagnosed, it can be treated and resolved and people start to feel better in just a few months’ time. Running on Empty Under normal circumstances, the adrenals (small walnut-sized glands that sit on top of the kidneys) produce numerous hormones -- adrenaline and others -- that impact bodily functions including blood pressure, heart rate and metabolism, liver function and immunity. They also produce two crucial stress hormones -- DHEA and cortisol -- whose job it is to balance the body’s response to stressful influences, including blood sugar fluctuations. According to Dr. Stengler, living with stress -- whether mental, physical or emotional -- for a protracted period results in a situation where the need for a constant supply of these two hormones outstrips the adrenals’ production of them. This deficiency dulls cognitive function, energy levels and, of course, your ability to handle stress. It also slows the immune response and with it the ability to fight off infections and even possibly cancer. DHEA and cortisol interact in complex ways that affect many functions -- deficiencies can contribute to cardiovascular disease, diabetes, weight gain, fatigue, allergies, infections, mood disorders and poor libido, says Dr. Stengler. To Know Whether You Have Adrenal Fatigue Fatigue is just one adrenal fatigue symptom. If you are chronically tired and have any of the following, you may want to consider asking your doctor for a blood or saliva (Dr. Stengler's preference) test to determine whether you have adrenal fatigue... Morning fatigue Mood swings Light-headedness after standing up Decreased sex drive Inability to focus Memory problems Body aches, including pain in the lower back Craving for salt and/or sugar Slower recovery from illness than is usual for you. Given the mainstream resistance to recognizing adrenal fatigue, Dr. Stengler suggests that those who think they may have it should seek out naturopathic physicians. Fixing Your Fatigue Once adrenal fatigue is diagnosed, treatment is multi-pronged, including a combination of nutrients and lifestyle changes: Stress reduction. Not surprisingly, your first task is to review what’s causing all the stress in your life so that you can determine what changes need to be made to reduce it. Get more sleep. You need plenty of high-quality, restorative sleep -- Dr. Stengler says to aim for eight to 10 hours every night, and he also advises taking daily naps. For those who have trouble falling asleep or who find themselves awakening in the night, he often prescribes 0.5 mg to 3 mg of melatonin, the "sleep" hormone, or 100 mg of the amino acid 5-HTP an hour before bedtime to help the body prepare for sleep. Ask your doctor which you should take. Adjust your diet. Dr. Stengler points out that people with adrenal fatigue often have blood sugar swings and cravings for sweets, so it’s very important to have breakfast every day and to eat small, healthy snacks between meals. He advises eating plenty of whole-grain foods and protein, including almonds, walnuts and macadamia nuts, and avoiding processed foods and simple sugars, including refined grains, fruit juices and, of course, sugary sodas. Also stay away from caffeinated beverages and alcohol. And if you have low blood pressure, which often results from adrenal fatigue and further contributes to fatigue, do be sure you are getting enough salt, which helps maintain blood volume and proper circulation. However, don’t go overboard -- 2,400 mg per day of sodium from all sources is usually about right. Exercise -- in moderation. While exercise helps regulate stress hormones, too much will exhaust adrenal fatigue patients further, says Dr. Stengler. He advises his patients to start by walking 15 minutes a day, adding time as symptoms improve until reaching 45 minutes per day, but again, keeping it to a moderately intense level. Reduce the amount of exercise if afterward you find yourself feeling more tired rather than less -- the goal is to increase overall energy. Supplements To help speed recovery, Dr. Stengler often prescribes the following nutritional supplements... Vitamin B5 -- (pantothenic acid) is especially important for stress-hormone production... he often prescribes 500 mg of B5, three times a day. A good multivitamin (or B-complex) will supply enough of the other B vitamins needed, says Dr. Stengler. Vitamin C -- typically 1,000 mg to 2,000 mg twice daily is prescribed, but reduce this dose if loose stools develop. Adrenal glandular extract (AGE) -- made from cow, pig or sheep adrenals, AGE contains growth factors that promote cell healing and also has nutrients to support gland function and repair. Take one to two tablets daily without food, and reduce the dosage if you become jittery or have trouble sleeping. Ashwagandha -- this herb, popular in Ayurvedic medicine, helps normalize adrenal functioning. A brand Dr. Stengler often dispenses is Jarrow Sensoril Ashwagandha... typically one to two capsules are taken daily on an empty stomach. Rhodiola rosea -- most often, he directs his patients to take 500 mg twice a day away from food... he uses a standardized formula of 3% to 5% rosavins, such as Paradise Herbs’ Dual Action Rhodiola. Note: Those with bipolar disorder should not use this product, since it can increase brain levels of serotonin, a chemical that affects mood. Dr. Stengler said he sometimes uses hormone therapy consisting of DHEA, cortisol or other hormones and supplements to treat severe adrenal fatigue, but he noted that such measures require the supervision of a physician who is well practiced in the therapy. Effective adrenal fatigue treatment ends up being an intensive self-care regimen in which you ratchet back the unreasonable demands you’ve been making on your mind and body. Fortunately, given time to recover, the adrenals are able to regain their strength... and with it, your natural energy will return. Source(s): Mark A. Stengler, NMD, a naturopathic medical doctor and leading authority on the practice of alternative and integrated medicine. He is editor of the Bottom Line Natural Healing newsletter, author of The Natural Physician’s Healing Therapies (Bottom Line Books), director of the La Jolla Whole Health Clinic in La Jolla, California, and adjunct clinical professor at the National College of Natural Medicine in Portland, Oregon. To learn more about his work, visit www.drstengler.com and www.lajollawholehealth.com. Suzi List Owner health What is a weed? A plant whose virtues have not yet been discovered. Quote Link to comment Share on other sites More sharing options...
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