coQ10

[Guest guest]

>The other day somebody on the lyme list said they couldn't take CoQ10, and

another person said her doctor told her not to.

Some people are being treated for Lyme AND Babesia and the reasoning is that

CoQ10 cannot be taken when taking Atovaquone (Mepron), used to combat

Babesia. I think because it affects the action of Atovaquone.

Nelly

[Guest guest]

Ihave actually suspected that co-q10 might be making me feel worse.

I started in in December and heard Cheney was recommending high doses

and went up (though knew I couldn't afford it really for long) and

was taking 400. Initially I seemed to feel stronger.

I accidentally overdid it and had the worst/most painful crash I can

remember. It didn't even make sense given what I know about myself.

That partially contributed to the depression and I kept wondering if

co-q could in some affect the brain in that way but didn't ask

because it sounded stupid.

I've gone off it and sometimes go back and take 100 but what is

happening is that as I try to regain mobility after this crash I'm

having a very hard time. I cannot seem to achieve anything near my

former functioning (which is depressing me) even if there's no pain

or tiredness while walking very little.

I simoply do not know co-q's role in this, if any. My muscles thru

some biochem process simply are not as conditionable by a long shot.

I don't know if I should drop off the co-q for a while completely or

just stay at 100. It is , with us, so confusing.

But it's so hard to be so less functional in terms of independent

living.

Judith Wisdom

> Has anyone had bad effects from CoQ10?

>

..

>

> Rich, can you think of any biochemical reason why this might happen?

> Thanks,

> Doris

>

>

[Guest guest]

Doris,

I'm not sure what is going on with the Co Q-10 in your case, since

as far as I have been able to determine, it is usually well

tolerated, even up to doses of 600 mg per day.

I'll give you some possibilities to consider. Please bear in mind

that these are speculative.

1. The particular brand of Co Q-10 you were taking has some

impurity in it that was actually causing the problems.

2. Your body is deficient in alpha lipoic acid, which normally

regenerates the coenzyme Q-10 (chemically reduces it so it can be

used again). There needs to be a balance between the network

antioxidants for them to function properly. (I don't know whether

buildup of oxidized Co Q-10 is actually a problem or not, but it's

just something that occurs to me, since there have been problems

with other antioxidants when used separately at high doses.)

3. Your brain is ischemic. That is, it isn't receiving a high

enough rate of blood supply. This can produce hypoxia, or too low

an oxygen level in the tissue. Under these conditions, Coenzyme Q-

10 can autooxidize, donating electrons to the oxygen molecules that

are available, thus forming superoxide free radicals, which can in

turn produce oxidative damage to the lipids in the cells. Steve

Levine and Parris Kidd mention this in their book " Antioxidant

Adaptation, Its Role in Free Radical Pathology, " Allergy Research

Group, San Leandro, CA, 1985, p.143.

Rich

> Has anyone had bad effects from CoQ10?

>

> I have been really slacking off the supplements lately because one

of them is making me feel yucky, but I couldn't figure out which. I

was trying to eliminate them one by one. First curcumin, then b

vitamins, then omega oils, etc... The other day somebody on the

lyme list said they couldn't take CoQ10, and another person said her

doctor told her not to. So I figured what they heck. So for 2 days

now I have taken all the supplements except the CoQ10 and I have

felt fine. I was taking 100mg.

>

> Rich, can you think of any biochemical reason why this might

happen?

> Thanks,

> Doris

>

>

[Guest guest]

In a message dated 5/14/03 1:23:28 PM Pacific Daylight Time,

ng2113@... writes:

> " . Your brain is ischemic. That is, it isn't receiving a high

> enough rate of blood supply. This can produce hypoxia, or too low

> an oxygen level in the tissue. Under these conditions, Coenzyme Q-

> 10 can autooxidize, donating electrons to the oxygen molecules that

> are available, thus forming superoxide free radicals, which can in

> turn produce oxidative damage to the lipids in the cells. Steve

> Levine and Parris Kidd mention this in their book " Antioxidant

> Adaptation, Its Role in Free Radical Pathology, " Allergy Research

> Group, San Leandro, CA, 1985, p.143. "

I think Rich posted this....Rich, do you know how one would offset this from

happening when taking q10?

[Guest guest]

" . Your brain is ischemic. That is, it isn't receiving a high

enough rate of blood supply. This can produce hypoxia, or too low

an oxygen level in the tissue. Under these conditions, Coenzyme Q-

10 can autooxidize, donating electrons to the oxygen molecules that

are available, thus forming superoxide free radicals, which can in

turn produce oxidative damage to the lipids in the cells. Steve

Levine and Parris Kidd mention this in their book " Antioxidant

Adaptation, Its Role in Free Radical Pathology, " Allergy Research

Group, San Leandro, CA, 1985, p.143. "

Rich,

This is very interesting. Thanks.Which types supplements one should be

careful of if he has a blood flow problem to the brain. I do and my brain

problems keep getting worse.After reading your note I thought I might also

suffer the same problem. I don't use co q10 but I use various other

supplements. Vitamins,flax,minerals,glanulars. I noticed something

interesting. I was taking Vit A. I got the feeling that it was not good for

me. I stopped taking it.What about Vit E?Flax?Selenium? Bioflovanoids?

Thanks.

Nil

Re: CoQ10

| Doris,

|

| I'm not sure what is going on with the Co Q-10 in your case, since

| as far as I have been able to determine, it is usually well

| tolerated, even up to doses of 600 mg per day.

|

| I'll give you some possibilities to consider. Please bear in mind

| that these are speculative.

|

| 1. The particular brand of Co Q-10 you were taking has some

| impurity in it that was actually causing the problems.

|

| 2. Your body is deficient in alpha lipoic acid, which normally

| regenerates the coenzyme Q-10 (chemically reduces it so it can be

| used again). There needs to be a balance between the network

| antioxidants for them to function properly. (I don't know whether

| buildup of oxidized Co Q-10 is actually a problem or not, but it's

| just something that occurs to me, since there have been problems

| with other antioxidants when used separately at high doses.)

|

| 3. Your brain is ischemic. That is, it isn't receiving a high

| enough rate of blood supply. This can produce hypoxia, or too low

| an oxygen level in the tissue. Under these conditions, Coenzyme Q-

| 10 can autooxidize, donating electrons to the oxygen molecules that

| are available, thus forming superoxide free radicals, which can in

| turn produce oxidative damage to the lipids in the cells. Steve

| Levine and Parris Kidd mention this in their book " Antioxidant

| Adaptation, Its Role in Free Radical Pathology, " Allergy Research

| Group, San Leandro, CA, 1985, p.143.

|

| Rich

|

|

| > Has anyone had bad effects from CoQ10?

| >

| > I have been really slacking off the supplements lately because one

| of them is making me feel yucky, but I couldn't figure out which. I

| was trying to eliminate them one by one. First curcumin, then b

| vitamins, then omega oils, etc... The other day somebody on the

| lyme list said they couldn't take CoQ10, and another person said her

| doctor told her not to. So I figured what they heck. So for 2 days

| now I have taken all the supplements except the CoQ10 and I have

| felt fine. I was taking 100mg.

| >

| > Rich, can you think of any biochemical reason why this might

| happen?

| > Thanks,

| > Doris

| >

| >

[Guest guest]

Hi Doris,

> Has anyone had bad effects from CoQ10?

I've had nothing but great results from it. Really increased my energy.

> I have been really slacking off the supplements lately because one of them is

making me feel yucky, but I couldn't figure out which. I was trying to

eliminate them one by one. First curcumin, then b vitamins, then omega oils,

etc... The other day somebody on the lyme list said they couldn't take CoQ10,

and another person said her doctor told her not to. So I figured what they

heck. So for 2 days now I have taken all the supplements except the CoQ10 and I

have felt fine. I was taking > 100mg.

Do you take all your supplements in divided doses? You really should.

That keeps levels more even through each 24 hr. period. I take 100mg.

also ... 50 in the morning, 50 in the evening.

Teewinot

@>--}-- * --{--<@

Teewinot13@...

[Guest guest]

rvankonynen wrote:

>3. Your brain is ischemic. That is, it isn't receiving a high

>enough rate of blood supply. This can produce hypoxia, or too low

>an oxygen level in the tissue. Under these conditions, Coenzyme Q-

>10 can autooxidize, donating electrons to the oxygen molecules that

>are available, thus forming superoxide free radicals, which can in

>turn produce oxidative damage to the lipids in the cells. Steve

>Levine and Parris Kidd mention this in their book " Antioxidant

>Adaptation, Its Role in Free Radical Pathology, " Allergy Research

>Group, San Leandro, CA, 1985, p.143.

>

>Rich,

>

Isn't this true of most of us pwcs? Aren't all of our brains low in

blood supply?

Tracey

>

>

>-

>

>

>

>

>

>

[Guest guest]

You can offset this from taking Idebenone instead of CoQ10.

-O

> In a message dated 5/14/03 1:23:28 PM Pacific Daylight Time,

> ng2113@s... writes:

>

> > " . Your brain is ischemic. That is, it isn't receiving a high

> > enough rate of blood supply. This can produce hypoxia, or too low

> > an oxygen level in the tissue. Under these conditions, Coenzyme

Q-

> > 10 can autooxidize, donating electrons to the oxygen molecules

that

> > are available, thus forming superoxide free radicals, which can in

> > turn produce oxidative damage to the lipids in the cells. Steve

> > Levine and Parris Kidd mention this in their book " Antioxidant

> > Adaptation, Its Role in Free Radical Pathology, " Allergy Research

> > Group, San Leandro, CA, 1985, p.143. "

>

>

>

> I think Rich posted this....Rich, do you know how one would offset

this from

> happening when taking q10?

>

>

>

[Guest guest]

Nil, , Tracey, O., Judith, Cbuf, Nelly, Doris and the group,

It looks like I really stirred the pot with this suggested

hypothesis about how coenzyme Q-10 might be causing Doris to

feel " yucky. "

Let me first reiterate that this is just a hypothesis. I don't know

if it is truly what is going on in Doris's case, or any other case

of CFS. It was one of three hypotheses that I suggested.

It's true that there is evidence in the literature that coenzyme Q-

10 can auto-oxidize and produce superoxide free radicals under

ischemic conditions.

It's true that SPECT studies in some PWCs have shown low blood

perfusion in parts of the brain. I don't know whether all PWCs have

low blood perfusion in the brain. I also don't know whether the

ischemia in those PWCs who have low blood perfusion in parts of

their brain is severe enough to cause conditions in which coenzyme Q-

10 will auto-oxidize.

It's true that there are studies in the literature showing that the

drug idebenone is protective against free radical damage during

ischemia. Apparently it does this by stimulating production of

nerve growth factor. Someone on the list mentioned recently that

Dr. Cheney has started to try it in PWCs for this reason.

Coenzyme Q-10 is an orthomolecular substance, i.e. it is found

normally in the body. We all need to have some in our bodies, and

supplementing it has been found to be beneficial by many PWCs. I

think it's a good idea not to take too much, though. Prof. Lester

Packer recommends taking 30 mg per day in his basic antioxidant plan

( " The Antioxidant Miracle " ), and an additional 50 mg per day for

those who are at high risk for heart disease or stroke.

As for the other antioxidant supplements, I think it's wise to limit

selenium and vitamin E supplementation, also. An upper limit on

selenium of 200 micrograms per day and an upper limit on vitamin E

of 1,000 mg per day are suggested by the Institute of Medicine. (For

dl alpha tocopherol, the latter is equivalent to 1,000 I.U. per

day). Rob Napier mentioned a while back on the list that this

amount of selenium was too high in his case. I think Dr. Cheney has

recommended limiting vitamin C to 2,000 mg per day if glutathione is

low, and I don't know of a limit for the bioflavonoids.

Rich

> > In a message dated 5/14/03 1:23:28 PM Pacific Daylight Time,

> > ng2113@s... writes:

> >

> > > " . Your brain is ischemic. That is, it isn't receiving a high

> > > enough rate of blood supply. This can produce hypoxia, or too

low

> > > an oxygen level in the tissue. Under these conditions,

Coenzyme

> Q-

> > > 10 can autooxidize, donating electrons to the oxygen molecules

> that

> > > are available, thus forming superoxide free radicals, which

can in

> > > turn produce oxidative damage to the lipids in the cells.

Steve

> > > Levine and Parris Kidd mention this in their book " Antioxidant

> > > Adaptation, Its Role in Free Radical Pathology, " Allergy

Research

> > > Group, San Leandro, CA, 1985, p.143. "

> >

> >

> >

> > I think Rich posted this....Rich, do you know how one would

offset

> this from

> > happening when taking q10?

> >

> >

> >

[Guest guest]

Hi All,

I have been taking CoQ10 for years basically, just on general

principals that

it could be helpful. I can't say that it has helped me. I recently

listened to a

nutritionist on a radio program that said that 1000mg of CoQ10 could

arrest

Parkinson's disease. I will take that with a grain of salt. I also heard

that

these anti-cholesterol drugs, in some people can deplete CoQ10 and cause

muscle problems. I try to be on the safe side and since I have muscle

problems

and heart palpatations, at times, for me I feel that it can't hurt and

maybe will

help to some degree.

Mike

[Guest guest]

>Does anyone have the address of sites devoted to CoQ10?   Bob

Here abstracts of 2 papers, Q10 is a fat soluble molecule, commercial

preparations are low dose and expensive, these may even not be very bioavailable

and

may contain unacceptable filling substances, maybe they are not allowed to

sell their crab in a higher dose or they are too greedy of money, I dont know.

I am sure however the right thing in the right dose at the right price is

worth using in any type of cancer in case someone avoids detrimental mistakes in

his nutrition.

best regards, Juergen Boehm

Biochem Biophys Res Commun. 1995 Jul 6;212(1):172-7.

Progress on therapy of breast cancer with vitamin Q10 and the regression of

metastases.

Lockwood K, Moesgaard S, Yamamoto T, Folkers K.

Pharma Nord, Vejle, Denmark.

Over 35 years, data and knowledge have internationally evolved from

biochemical, biomedical and clinical research on vitamin Q10 (coenzyme Q10;

CoQ10) and

cancer, which led in 1993 to overt complete regression of the tumors in two

cases of breast cancer. Continuing this research, three additional breast cancer

patients also underwent a conventional protocol of therapy which included a

daily oral dosage of 390 mg of vitamin Q10 (Bio-Quinone of Pharma Nord) during

the complete trials over 3-5 years. The numerous metastases in the liver of a

44-year-old patient " disappeared, " and no signs of metastases were found

elsewhere. A 49-year-old patient, on a dosage of 390 mg of vitamin Q10, revealed

no

signs of tumor in the pleural cavity after six months, and her condition was

excellent. A 75-year-old patient with carcinoma in one breast, after

lumpectomy and 390 mg of CoQ10, showed no cancer in the tumor bed or metastases.

Control blood levels of CoQ10 of 0.83-0.97 and of 0.62 micrograms/ml increased

to

3.34-3.64 and to 3.77 micrograms/ml, respectively, on therapy with CoQ10 for

patients A-MRH and EEL.

Biochem Biophys Res Commun. 1994 Mar 30;199(3):1504-8.

Partial and complete regression of breast cancer in patients in relation to

dosage of coenzyme Q10.

Lockwood K, Moesgaard S, Folkers K.

Pharma Nord, Vejle, Denmark.

Relationships of nutrition and vitamins to the genesis and prevention of

cancer are increasingly evident. In a clinical protocol, 32 patients having

- " high-risk " - breast cancer were treated with antioxidants, fatty acids, and 90

mg.

of CoQ10. Six of the 32 patients showed partial tumor regression. In one of

these 6 cases, the dosage of CoQ10 was increased to 390 mg. In one month, the

tumor was no longer palpable and in another month, mammography confirmed the

absence of tumor. Encouraged, another case having a verified breast tumor, after

non-radical surgery and with verified residual tumor in the tumor bed was then

treated with 300 mg. CoQ10. After 3 months, the patient was in excellent

clinical condition and there was no residual tumor tissue. The bioenergetic

activity of CoQ10, expressed as hematological or immunological activity, may be

the

dominant but not the sole molecular mechanism causing the regression of breast

cancer.

[Guest guest]

http://www.google.com/search?hl=en & lr= & ie=ISO-8859-1 & q=CoQ10+cancer+research

http://www.google.com/search?hl=en & lr= & ie=ISO-8859-1 & q=CoQ10+research & btnG=Googl\

e+Search

http://www.google.com/search?hl=en & ie=ISO-8859-1 & q=CoQ10

bob smith wrote:

> Does anyone have the address of sites devoted to CoQ10? Bob

>

****Aerielle Louise * Sr. Exec. V.P.****

**THE LOU GENTILE NETWORK**

******http://www.lougentile.com*******

[Guest guest]

From: bob smith <rresmith@...>

> Does anyone have the address of sites devoted to CoQ10 [and cancer]?

http://cancernet.nci.nih.gov/cam/Q10.htm

www.mercola.com/2000/sept/10/coq10_cancer.htm

www.chiro.org/places/Q10.shtml#Cancer

www.bioimmune.com/newsletter/index.asp?id=123#1

www.ashapharma.com/breast.htm

www.ashapharma.com/volume.htm

www.webcom.com/cfsc/cancer.html

www.thenutritionreporter.com/CoenzymeQ10.html

www.lef.org/magazine/mag96/96jan1f.htm

www.mdanderson.org/departments/CIMER/display.cfm?id=43EF7F77-0DAF-11D5-810D00508

B603A14 & method=displayFull & pn=6EB86A59-EBD9-11D4-810100508B603A14

[Guest guest]

>

> Hello all. Does anyone have dosages of CoQ10 for an 80lb child?

How

> many mg's, how often, experiences good or bad? Thanks in advance.

>

> Tina

Hi Tina,

I give my 6yr 44lbs. son 50mg twice a day. I started by giving him

25mg twice a day and increased after two weeks. I saw improvement in

his memory and mood. CoQ10 is a great anti-oxidant we could all

benefit from taking it. It is especially important for thoses who

are on a limited dietary intake of a variety of fruits and

vegatables.

Aminah

[Guest guest]

Mike

coQ10 has always had the same effect on me, I've tried very low doses a couple

different times and made me feel worse so I gave up.

Marcia

CoQ10

Again I was wondering if anyone had any problems when they started

taking this supplement. I have only been taking 30 mg./day, but

my energy level went way down the first three days that I took it.

Maybe it's just me, or I'm not taking it right or something. Thanks,

Mike C.

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

[Guest guest]

Hi Mike -

I wonder if a different brand or type would make a difference. I

started it years ago at 100mg 2x/day with no problem, then switched

to a sale brand and couldn't handle it.

I've gone through several types before realizing my body really likes

Now brand softgels with Rice Bran Oil and Vit E. (and doesn't like

Now brand V-caps - which is a shame, they're always cheaper).

Of course, it could be your body doesn't want CoQ10 at all...

Take care. -Lynn

[Guest guest]

Thanks, it's hard to know what the issue is. I am taking Now brand

(was taking) in the powdered capsule form, but it is hard for me

to think that softgels made by the same company would be any better.

After reading Dan's post, I went to my supplement cabinet and found

an old supplement w/ 175 mg. of L-Carnitine, 10 mg. of CoQ10 and

10 mg. of Vit B5. It is a Jarrow brand. So Jarrow must think

1)that L-Carnitine needs to be taken w/ CoQ10, and 2)that a lower

dose of CoQ10 is in order. Jarrow calls it a 'synergistic formula'.

FWIW,

Mike C

- In , " Lynn " <lkpumpkin@h...>

wrote:

> Hi Mike -

>

> I wonder if a different brand or type would make a difference. I

> started it years ago at 100mg 2x/day with no problem, then switched

> to a sale brand and couldn't handle it.

>

> I've gone through several types before realizing my body really

likes

> Now brand softgels with Rice Bran Oil and Vit E. (and doesn't like

> Now brand V-caps - which is a shame, they're always cheaper).

>

> Of course, it could be your body doesn't want CoQ10 at all...

>

> Take care. -Lynn

[Guest guest]

Mike,

L-carnitine is the " usher " that brings longer-chain fatty acids into

the mitochondria to be broken down by the process of beta oxidation.

Vitamin B5 is used to make coenzyme A, which introduces fragments of

fatty acids from beta oxidation (as well as processed carbohydrates

from glycolysis) into the Krebs cycle to be oxidized.

Co Q10 serves as the entry to the respiratory chain for energetic

electrons derived from the oxidation of fuels by the glycolysis

chain and the Krebs cycle. The energy in these electrons is used to

produce ATP, the energy currency of the cell.

These three nutrients taken together are probably thus intended to

help the cells burn fats and make ATP.

The combination of L-carnitine and Co Q-10 has been used in Japan

and Europe quite a bit to treat congestive heart failure. The idea

is to help the heart muscle cells generate ATP more rapidly from

fatty acids, which are the main fuel for the heart muscle, and thus

to help the heart muscle do its job of pumping blood in a more

powerful way.

Rich

> > Hi Mike -

> >

> > I wonder if a different brand or type would make a difference. I

> > started it years ago at 100mg 2x/day with no problem, then

switched

> > to a sale brand and couldn't handle it.

> >

> > I've gone through several types before realizing my body really

> likes

> > Now brand softgels with Rice Bran Oil and Vit E. (and doesn't

like

> > Now brand V-caps - which is a shame, they're always cheaper).

> >

> > Of course, it could be your body doesn't want CoQ10 at all...

> >

> > Take care. -Lynn

[Guest guest]

Thanks Rich-but why the low dose (10 mg.) of CoQ10 in the Jarrow

formula? No critisim, but if you choose to explain, please pretend

like you are explaining to a teenager. Thanks,

Mike C.

> > Thanks, it's hard to know what the issue is. I am taking Now

brand

> > (was taking) in the powdered capsule form, but it is hard for me

> > to think that softgels made by the same company would be any

> better.

> > After reading Dan's post, I went to my supplement cabinet and

found

> > an old supplement w/ 175 mg. of L-Carnitine, 10 mg. of CoQ10 and

> > 10 mg. of Vit B5. It is a Jarrow brand. So Jarrow must think

> > 1)that L-Carnitine needs to be taken w/ CoQ10, and 2)that a lower

> > dose of CoQ10 is in order. Jarrow calls it a 'synergistic

> formula'.

> > FWIW,

> >

> > Mike C

[Guest guest]

So how much of each does one need to take?

thank you

lea

> The combination of L-carnitine and Co Q-10 has been used in Japan

> and Europe quite a bit to treat congestive heart failure. The idea

> is to help the heart muscle cells generate ATP more rapidly from

> fatty acids, which are the main fuel for the heart muscle, and thus

> to help the heart muscle do its job of pumping blood in a more

> powerful way.

>

> Rich

>

[Guest guest]

Hi, lea.

For Co Q-10, I've heard of doses from 100 to 600 milligrams. The

higher dose is usually associated with treating things like

mitochondrial diseases. Co Q-10 is fairly expensive, and that is

unfortunately a factor in dosing for many people.

For L-carnitine, I've heard of doses in the range of 1 to 3 grams

(1,000 to 3,000 milligrams). If acetyl-L-carnitine is used instead,

the doses are usually about half as much.

As with everything else taken in CFS, I suggest starting low and

moving up slowly as things are tolerated.

Rich

> So how much of each does one need to take?

> thank you

> lea

>

>

> > The combination of L-carnitine and Co Q-10 has been used in Japan

> > and Europe quite a bit to treat congestive heart failure. The

idea

> > is to help the heart muscle cells generate ATP more rapidly from

> > fatty acids, which are the main fuel for the heart muscle, and

thus

> > to help the heart muscle do its job of pumping blood in a more

> > powerful way.

> >

> > Rich

> >

[Guest guest]

Hi ,

Below are excerpts from an article on the differences in the quality

of supplements. For more information, the link to the full article is

at the bottom of the page.

------------------

Uneven Playing Field

Growth in the supplements industry is so red hot that the mainstays

are issuing warnings. " Many of these players do not know anything

about dietary supplements or botanicals, " says Nature's Way chairman,

Ken Murdock, " It's just a business opportunity for them. " Murdock

believes an increasing number of companies are pumping out poor

quality supplement products.

Enzymatic Therapy's vice-president of scientific affairs, Matt

Schueller, calls it a " wild, wild west situation. " For instance, he

says, " A consumer may go out and see two bottles next to each other

and they both say ginkgo extract with 40 milligrams per capsule. One

may be on the shelf for $20 and the other for $7. " What often happens

he says is that the cheap product " is not concentrated, the levels of

the compounds may vary from what's been used in clinical research. It

may have higher levels of impurities. These are things that may not

always make it onto the label. "

Expert Testimony

True to supply and demand, the suppliers from whom the supplement

companies are getting their raw ingredients are proliferating too.

Many of these, according to biochemist Tom Guilliams, Ph.D. in

molecular immunology, who directs R & D at Ortho Molecular Products,

are springing up in China and producing " active " ingredients

(vitamins, minerals, etc.) of very low quality. " Some companies will

use forms of minerals or vitamins that are less absorbable, very

inexpensive, and not as good as others. " Much of it, he says, is used

in animal feed but also channeled into supplements for human use.

Guilliams audits the international scene of supplement materials for

Ortho Molecular, a high-end supplement company that sells exclusively

to health care practitioners for resale to their patients. From his

lab in s Point, Wisconsin, he scouts the world for quality raw

materials to create the supplements that are in the company's product

line. Ortho imports about three hundred different raw ingredients,

typical for a company with their size product line.

I asked Guilliams, " Will a cheap and badly made supplement carry any

benefit at all? " " In many cases it will, " he replied. But he

indicated that it's a crap shoot. " It'd be like saying, if I go to a

used car dealer can I get a good car? The answer would be 'yes,'

sometimes. In the case of vitamins and minerals...some companies will

use a lot of binders and a lot of fillers. [in addition] some forms

of minerals and vitamins are less absorbable and not as good as

others. Usually, but not always, you get what you pay for. "

So imagine a supplement company that buys the low grade vitamins,

minerals, etc. and combines them with cheap and/or excessive amounts

of binders and fillers plus unhealthy colorings, flavors, or

preservatives. If corners are cut and inferior active and inactive

ingredients are used, chances are your body won't get the presumed

benefit of the supplement. In fact, various additives contain toxins

that would be hard on the liver or cause allergic reactions.

Will it be Capsules, Tablets or Liquid?

A hybrid form of the capsule is the soft-gel. This, according to

Guilliams, is the best dosage form for oil-based active ingredients

such as vitamin E, CoQ10, saw palmetto, and the various essential

oils such as flax, evening primrose, and pumpkin seed. Because these

supplements are highly susceptible to spoilage, the soft gels fuse an

airtight seal and protect the properties from oxygen and light.

http://www.consciouschoice.com/1999/cc1208/supplements1208.html

rmireles34 wrote:

>Does anyone know if there is really a difference in quality,

> effectiveness, in different brands of CoQ10.

> I got some from my naturopath - brand is PhysioLogics -60 - 200mg

caps for $83.99. Got some from Costco - brand is TruNature -75 -

150mg caps for $25. Also saw some on the internet that were over $100.

> I know that some of you are using the ones from Costco. I don't

want to shortchange my body, but don't want to waste my money when

the cheaper one will do the job. Thanks ,

[Guest guest]

I use yournutritionshop.com and it has a lot of stuff in liquid form

including CoQ10 which takes in yoghurt or juice and does not seem

to taste. I find the organisation very good and if you order normally

arrives next day.

>

> Which brand of CoQ10 do people use for kids who won't swallow

tablets, that can be disguised in food or drink and that doesn't taste

too bad?? Does such a product exist? Also, Acetyl L-Carnitine?

>

> Thank you,

> Diane

>

[Guest guest]

Hi Diane

We use Metabolics COQ10 30mg small capsules.

We empty into a drink...Best with some kind of oil so we do at the

same time as Kirkmans Cod liver oil.( and about 5 other things in

one go !)

www.metabolics.co.uk

Look up products and then vitamins.

Joanne

>

> Which brand of CoQ10 do people use for kids who won't swallow

tablets, that can be disguised in food or drink and that doesn't

taste too bad?? Does such a product exist? Also, Acetyl L-Carnitine?

>

> Thank you,

> Diane

>

[Guest guest]

Diane

Metabolics also do acetyl L-Carnitine

Look it up under amino acids.

Joanne

>

> Which brand of CoQ10 do people use for kids who won't swallow

tablets, that can be disguised in food or drink and that doesn't taste

too bad?? Does such a product exist? Also, Acetyl L-Carnitine?

>

> Thank you,

> Diane

>