Guest guest Posted December 21, 2008 Report Share Posted December 21, 2008 I switched over from Spiro to Inspra several years ago. The biggest issue I had was the cost. However, the " bad " side-effects of the spiro went away. Gynecomastia went away. Had to play with the dosage to get things right as far as BP & electrolytes go. Headaches did not seem to change any with the switch over. Depression ... not really sure as things change sometimes on a daily basis. ~Dave K > > Recently had a slight kidney failure problem going up to 136 on creatinine after three to four weeks on spiro - 75 mg and amiloride 20 mg a day > Now  on 10 mg amiloride and 50 mg spiro per day with as high levels of potassium as I can get up to and no added salt. Was also on 20 mg Zanidip but does not appear to be really contributing very much. BP around 140/90 - sometimes slightly higher at 145 - from time to time slight drops to 135/85 approx. Range now appears to be 140/90. Creatinine now at around 110 - just ten below the normal upper limit. > > Gynecomastia still happening and so being switched to 50 mg Inspra after the Xmas break. 50 mg appears to be available in Oz but as not subsidised will be very expensive. Will still be on amiloride 10 mg with twice weekly blood tests. Information about headaches and depression from other folks have all been closely and gratefully taken on board - including earlier comments that with Inspra, you need to take it into your system slowly. > > Also I now have a persistent slight to medium swelling in feet, ankles and lower legs - have not been on Zanidip or Norvasc for almost a month now, so not sure where this is coming from - maybe related to kidney issues earlier and it has just not cleared up. > > Gets quite bad when I sit at computer for long periods of time. Not significantly relieved by putting my feet up. > > Any comments or suggestions from people familiar with changing over from Spiro to Inspra welcome. > > Merry xmas to all > > Kwame > > > Stay connected to the people that matter most with a smarter inbox. Take a look http://au.docs./mail/smarterinbox > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2008 Report Share Posted December 21, 2008 Do you think DASHing has helped Sent from my iPhone CE Grim MD On Dec 21, 2008, at 4:09 PM, bigdogdkiedrow <bigdogdkiedrow@...> wrote: > I switched over from Spiro to Inspra several years ago. The biggest > issue I had was the cost. However, the " bad " side-effects of the > spiro went away. Gynecomastia went away. Had to play with the dosage > to get things right as far as BP & electrolytes go. Headaches did not > seem to change any with the switch over. Depression ... not really > sure as things change sometimes on a daily basis. > > ~Dave K > > > > > > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride > 20 mg a day > > Now  on 10 mg amiloride and 50 mg spiro per day with as high > levels of potassium as I can get up to and no added salt. Was also on > 20 mg Zanidip but does not appear to be really contributing very > much. BP around 140/90 - sometimes slightly higher at 145 - from time > to time slight drops to 135/85 approx. Range now appears to be > 140/90. Creatinine now at around 110 - just ten below the normal > upper limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > after the Xmas break. 50 mg appears to be available in Oz but as not > subsidised will be very expensive. Will still be on amiloride 10 mg > with twice weekly blood tests. Information about headaches and > depression from other folks have all been closely and gratefully > taken on board - including earlier comments that with Inspra, you > need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > ankles and lower legs - have not been on Zanidip or Norvasc for > almost a month now, so not sure where this is coming from - maybe > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > > > Stay connected to the people that matter most with a smarter > inbox. Take a look http://au.docs./mail/smarterinbox > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2008 Report Share Posted December 22, 2008 The swelling is most likely due to Norvasc and eating too much salt. You should be able to taper it as Inspra kicks in. Again DASHing potentiates all BP Rx esp in PA. I forgot if you are of African descent (well recently as all of us are of African descent). Is so the AASK study suggested that Norvasc may not be the best choice if you have renal damage. Any protein in urine? On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride > 20 mg a day > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > of potassium as I can get up to and no added salt. Was also on 20 > mg Zanidip but does not appear to be really contributing very much. > BP around 140/90 - sometimes slightly higher at 145 - from time to > time slight drops to 135/85 approx. Range now appears to be 140/90. > Creatinine now at around 110 - just ten below the normal upper limit. > > Gynecomastia still happening and so being switched to 50 mg Inspra > after the Xmas break. 50 mg appears to be available in Oz but as > not subsidised will be very expensive. Will still be on amiloride > 10 mg with twice weekly blood tests. Information about headaches > and depression from other folks have all been closely and > gratefully taken on board - including earlier comments that with > Inspra, you need to take it into your system slowly. > > Also I now have a persistent slight to medium swelling in feet, > ankles and lower legs - have not been on Zanidip or Norvasc for > almost a month now, so not sure where this is coming from - maybe > related to kidney issues earlier and it has just not cleared up. > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > Any comments or suggestions from people familiar with changing over > from Spiro to Inspra welcome. > > Merry xmas to all > > Kwame > > Stay connected to the people that matter most with a smarter inbox. > Take a lookhttp://au.docs./mail/smarterinbox > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2008 Report Share Posted December 22, 2008 I do. My BP has dropped (since dashing) to an average of 125/72. Before spiro and dashing I was running 185/125. On Inspra alone I was running about 125/80. ~Dave K. > > > > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > > Now  on 10 mg amiloride and 50 mg spiro per day with as high > > levels of potassium as I can get up to and no added salt. Was also on > > 20 mg Zanidip but does not appear to be really contributing very > > much. BP around 140/90 - sometimes slightly higher at 145 - from time > > to time slight drops to 135/85 approx. Range now appears to be > > 140/90. Creatinine now at around 110 - just ten below the normal > > upper limit. > > > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as not > > subsidised will be very expensive. Will still be on amiloride 10 mg > > with twice weekly blood tests. Information about headaches and > > depression from other folks have all been closely and gratefully > > taken on board - including earlier comments that with Inspra, you > > need to take it into your system slowly. > > > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > > > Gets quite bad when I sit at computer for long periods of time. Not > > significantly relieved by putting my feet up. > > > > > > Any comments or suggestions from people familiar with changing over > > from Spiro to Inspra welcome. > > > > > > Merry xmas to all > > > > > > Kwame > > > > > > > > > Stay connected to the people that matter most with a smarter > > inbox. Take a look http://au.docs./mail/smarterinbox > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2008 Report Share Posted December 22, 2008 I had the high creatine shortly after I was put on Spiro too and it panicked the endo who first diagnosed me(whom I was her only PA patient too) sent me horridly to the nephrologist and told me I will be on dialysis in few months. But dont panic. Its because your body gets dehydrated. Next time you go for a kidney test, make sure you drink plenty of water before your test. In fact that is what the neph. did. Made me drink water and wait and then took a blood sample in his office and everything was normal then. As far as swelling in your feet, make sure its not caused by medication. I know that Norvasc(I am not sure if it is amiloride), causes severe edema in some people. Best of health to you. Farah On Sat, Dec 20, 2008 at 11:28 PM, kwame mfodwo <kmfodwo@...> wrote: > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride 20 mg a > day > Now on 10 mg amiloride and 50 mg spiro per day with as high levels of > potassium as I can get up to and no added salt. Was also on 20 mg Zanidip > but does not appear to be really contributing very much. BP around 140/90 - > sometimes slightly higher at 145 - from time to time slight drops to > 135/85 approx. Range now appears to be 140/90. Creatinine now at around 110 > - just ten below the normal upper limit. > > Gynecomastia still happening and so being switched to 50 mg Inspra after > the Xmas break. 50 mg appears to be available in Oz but as not subsidised > will be very expensive. Will still be on amiloride 10 mg with twice weekly > blood tests. Information about headaches and depression from other folks > have all been closely and gratefully taken on board - including earlier > comments that with Inspra, you need to take it into your system slowly. > > Also I now have a persistent slight to medium swelling in feet, ankles and > lower legs - have not been on Zanidip or Norvasc for almost a month now, so > not sure where this is coming from - maybe related to kidney issues earlier > and it has just not cleared up. > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > Any comments or suggestions from people familiar with changing over from > Spiro to Inspra welcome. > > Merry xmas to all > > Kwame > > Stay connected to the people that matter most with a smarter inbox. Take a > look http://au.docs./mail/smarterinbox > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2008 Report Share Posted December 22, 2008 Should be happy with just below 135/85. Goal is to get to this BP and not much lower and to have you feel well. On Dec 22, 2008, at 12:40 PM, bigdogdkiedrow wrote: > I do. My BP has dropped (since dashing) to an average of 125/72. > Before spiro and dashing I was running 185/125. On Inspra alone I was > running about 125/80. > > ~Dave K. > > > > > > > > > > Recently had a slight kidney failure problem going up to 136 on > > > creatinine after three to four weeks on spiro - 75 mg and > amiloride > > > 20 mg a day > > > > Now  on 10 mg amiloride and 50 mg spiro per day with as high > > > levels of potassium as I can get up to and no added salt. Was > also on > > > 20 mg Zanidip but does not appear to be really contributing very > > > much. BP around 140/90 - sometimes slightly higher at 145 - from > time > > > to time slight drops to 135/85 approx. Range now appears to be > > > 140/90. Creatinine now at around 110 - just ten below the normal > > > upper limit. > > > > > > > > Gynecomastia still happening and so being switched to 50 mg > Inspra > > > after the Xmas break. 50 mg appears to be available in Oz but > as not > > > subsidised will be very expensive. Will still be on amiloride 10 > mg > > > with twice weekly blood tests. Information about headaches and > > > depression from other folks have all been closely and gratefully > > > taken on board - including earlier comments that with Inspra, you > > > need to take it into your system slowly. > > > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > almost a month now, so not sure where this is coming from - > maybe > > > related to kidney issues earlier and it has just not cleared up. > > > > > > > > Gets quite bad when I sit at computer for long periods of time. > Not > > > significantly relieved by putting my feet up. > > > > > > > > Any comments or suggestions from people familiar with changing > over > > > from Spiro to Inspra welcome. > > > > > > > > Merry xmas to all > > > > > > > > Kwame > > > > > > > > > > > > Stay connected to the people that matter most with a smarter > > > inbox. Take a look http://au.docs./mail/smarterinbox > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2008 Report Share Posted December 22, 2008 how long does it usually take for Inspra to become fully effective? is it safe to go above the dose of 50 mg. bid? ======================================================================== == On Dec 22, 2008, at 10:43 AM, Clarence Grim wrote: > The swelling is most likely due to Norvasc and eating too much salt. > > You should be able to taper it as Inspra kicks in. > > Again DASHing potentiates all BP Rx esp in PA. > > I forgot if you are of African descent (well recently as all of us > are of African descent). Is so the AASK study suggested that Norvasc > may not be the best choice if you have renal damage. > > Any protein in urine? > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > of potassium as I can get up to and no added salt. Was also on 20 > > mg Zanidip but does not appear to be really contributing very much. > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > time slight drops to 135/85 approx. Range now appears to be 140/90. > > Creatinine now at around 110 - just ten below the normal upper > limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as > > not subsidised will be very expensive. Will still be on amiloride > > 10 mg with twice weekly blood tests. Information about headaches > > and depression from other folks have all been closely and > > gratefully taken on board - including earlier comments that with > > Inspra, you need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > Stay connected to the people that matter most with a smarter inbox. > > Take a lookhttp://au.docs./mail/smarterinbox > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 23, 2008 Report Share Posted December 23, 2008 Has usually maxed by 2-4 wks. Yes we go up to 400 but much cheaper to DASH. In general it will take 2 x as much Inspra as Spiro. CE Grim MD On Dec 22, 2008, at 11:18 PM, arthur springer wrote: > how long does it usually take for Inspra to become fully effective? > is it safe to go above the dose of 50 mg. bid? > ====================================================================== > == > == > > On Dec 22, 2008, at 10:43 AM, Clarence Grim wrote: > > > The swelling is most likely due to Norvasc and eating too much salt. > > > > You should be able to taper it as Inspra kicks in. > > > > Again DASHing potentiates all BP Rx esp in PA. > > > > I forgot if you are of African descent (well recently as all of us > > are of African descent). Is so the AASK study suggested that Norvasc > > may not be the best choice if you have renal damage. > > > > Any protein in urine? > > > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > > > Recently had a slight kidney failure problem going up to 136 on > > > creatinine after three to four weeks on spiro - 75 mg and > amiloride > > > 20 mg a day > > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > > of potassium as I can get up to and no added salt. Was also on 20 > > > mg Zanidip but does not appear to be really contributing very > much. > > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > > time slight drops to 135/85 approx. Range now appears to be > 140/90. > > > Creatinine now at around 110 - just ten below the normal upper > > limit. > > > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > > after the Xmas break. 50 mg appears to be available in Oz but as > > > not subsidised will be very expensive. Will still be on amiloride > > > 10 mg with twice weekly blood tests. Information about headaches > > > and depression from other folks have all been closely and > > > gratefully taken on board - including earlier comments that with > > > Inspra, you need to take it into your system slowly. > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > almost a month now, so not sure where this is coming from - maybe > > > related to kidney issues earlier and it has just not cleared up. > > > > > > Gets quite bad when I sit at computer for long periods of time. > Not > > > significantly relieved by putting my feet up. > > > > > > Any comments or suggestions from people familiar with changing > over > > > from Spiro to Inspra welcome. > > > > > > Merry xmas to all > > > > > > Kwame > > > > > > Stay connected to the people that matter most with a smarter > inbox. > > > Take a lookhttp://au.docs./mail/smarterinbox > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 23, 2008 Report Share Posted December 23, 2008 Had the same problem. I think you mean creatinine? Also get albumin and BUN and calculate using BMJ equation: Look at: http://ageing.oxfordjournals.org/cgi/content/full/35/2/ 121 Estimating renal function in older people: a comparison of three formulas Which has an enlightened approach to estimating GFR for olders, from serum data, and includes factors for BUN and serum albumin. Regards Re: My events so far I had the high creatine shortly after I was put on Spiro too and it panicked the endo who first diagnosed me(whom I was her only PA patient too) sent me horridly to the nephrologist and told me I will be on dialysis in few months. But dont panic. Its because your body gets dehydrated. Next time you go for a kidney test, make sure you drink plenty of water before your test. In fact that is what the neph. did. Made me drink water and wait and then took a blood sample in his office and everything was normal then. As far as swelling in your feet, make sure its not caused by medication. I know that Norvasc(I am not sure if it is amiloride), causes severe edema in some people. Best of health to you. Farah On Sat, Dec 20, 2008 at 11:28 PM, kwame mfodwo <kmfodwo@...> wrote: > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride 20 mg a > day > Now on 10 mg amiloride and 50 mg spiro per day with as high levels of > potassium as I can get up to and no added salt. Was also on 20 mg Zanidip > but does not appear to be really contributing very much. BP around 140/90 - > sometimes slightly higher at 145 - from time to time slight drops to > 135/85 approx. Range now appears to be 140/90. Creatinine now at around 110 > - just ten below the normal upper limit. > > Gynecomastia still happening and so being switched to 50 mg Inspra after > the Xmas break. 50 mg appears to be available in Oz but as not subsidised > will be very expensive. Will still be on amiloride 10 mg with twice weekly > blood tests. Information about headaches and depression from other folks > have all been closely and gratefully taken on board - including earlier > comments that with Inspra, you need to take it into your system slowly. > > Also I now have a persistent slight to medium swelling in feet, ankles and > lower legs - have not been on Zanidip or Norvasc for almost a month now, so > not sure where this is coming from - maybe related to kidney issues earlier > and it has just not cleared up. > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > Any comments or suggestions from people familiar with changing over from > Spiro to Inspra welcome. > > Merry xmas to all > > Kwame > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 yes - dashing has helped greatly ________________________________ From: Lowerbp2 <lowerbp2@...> " hyperaldosteronism " <hyperaldosteronism > Sent: Monday, 22 December, 2008 2:53:10 PM Subject: Re: Re: My events so far Do you think DASHing has helped Sent from my iPhone CE Grim MD On Dec 21, 2008, at 4:09 PM, bigdogdkiedrow <bigdogdkiedrow@ ..com> wrote: > I switched over from Spiro to Inspra several years ago. The biggest > issue I had was the cost. However, the " bad " side-effects of the > spiro went away. Gynecomastia went away. Had to play with the dosage > to get things right as far as BP & electrolytes go. Headaches did not > seem to change any with the switch over. Depression ... not really > sure as things change sometimes on a daily basis. > > ~Dave K > > > > > > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride > 20 mg a day > > Now  on 10 mg amiloride and 50 mg spiro per day with as high > levels of potassium as I can get up to and no added salt. Was also on > 20 mg Zanidip but does not appear to be really contributing very > much. BP around 140/90 - sometimes slightly higher at 145 - from time > to time slight drops to 135/85 approx. Range now appears to be > 140/90. Creatinine now at around 110 - just ten below the normal > upper limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > after the Xmas break. 50 mg appears to be available in Oz but as not > subsidised will be very expensive. Will still be on amiloride 10 mg > with twice weekly blood tests. Information about headaches and > depression from other folks have all been closely and gratefully > taken on board - including earlier comments that with Inspra, you > need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > ankles and lower legs - have not been on Zanidip or Norvasc for > almost a month now, so not sure where this is coming from - maybe > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > > > Stay connected to the people that matter most with a smarter > inbox. Take a look http://au.docs. / mail/smarterinbo x > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 have not been on CCBs for almost six weeks or more now. Swelling not related to CC although may have carried it over a bit from when on Zanidip which gave me much less swelling than Norvasc. Stopped Norvasc probably 4 months ago. No specific tests done on renal damage. Creatinine went up to 136, came down to 120-126 then now down to around 110. ________________________________ From: Clarence Grim <lowerbp2@...> hyperaldosteronism Sent: Tuesday, 23 December, 2008 2:43:54 AM Subject: Re: My events so far The swelling is most likely due to Norvasc and eating too much salt. You should be able to taper it as Inspra kicks in. Again DASHing potentiates all BP Rx esp in PA. I forgot if you are of African descent (well recently as all of us are of African descent). Is so the AASK study suggested that Norvasc may not be the best choice if you have renal damage. Any protein in urine? On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride > 20 mg a day > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > of potassium as I can get up to and no added salt. Was also on 20 > mg Zanidip but does not appear to be really contributing very much. > BP around 140/90 - sometimes slightly higher at 145 - from time to > time slight drops to 135/85 approx. Range now appears to be 140/90. > Creatinine now at around 110 - just ten below the normal upper limit. > > Gynecomastia still happening and so being switched to 50 mg Inspra > after the Xmas break. 50 mg appears to be available in Oz but as > not subsidised will be very expensive. Will still be on amiloride > 10 mg with twice weekly blood tests. Information about headaches > and depression from other folks have all been closely and > gratefully taken on board - including earlier comments that with > Inspra, you need to take it into your system slowly. > > Also I now have a persistent slight to medium swelling in feet, > ankles and lower legs - have not been on Zanidip or Norvasc for > almost a month now, so not sure where this is coming from - maybe > related to kidney issues earlier and it has just not cleared up. > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > Any comments or suggestions from people familiar with changing over > from Spiro to Inspra welcome. > > Merry xmas to all > > Kwame > > Stay connected to the people that matter most with a smarter inbox. > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 yes - African from Ghana ________________________________ From: kwame mfodwo <kmfodwo@...> hyperaldosteronism Sent: Thursday, 25 December, 2008 5:12:45 AM Subject: Re: My events so far have not been on CCBs for almost six weeks or more now. Swelling not related to CC although may have carried it over a bit from when on Zanidip which gave me much less swelling than Norvasc. Stopped Norvasc probably 4 months ago. No specific tests done on renal damage. Creatinine went up to 136, came down to 120-126 then now down to around 110. ____________ _________ _________ __ From: Clarence Grim <lowerbp2mac (DOT) com> hyperaldosteronism Sent: Tuesday, 23 December, 2008 2:43:54 AM Subject: Re: [hyperaldosteronism ] My events so far The swelling is most likely due to Norvasc and eating too much salt. You should be able to taper it as Inspra kicks in. Again DASHing potentiates all BP Rx esp in PA. I forgot if you are of African descent (well recently as all of us are of African descent). Is so the AASK study suggested that Norvasc may not be the best choice if you have renal damage. Any protein in urine? On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > Recently had a slight kidney failure problem going up to 136 on > creatinine after three to four weeks on spiro - 75 mg and amiloride > 20 mg a day > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > of potassium as I can get up to and no added salt. Was also on 20 > mg Zanidip but does not appear to be really contributing very much. > BP around 140/90 - sometimes slightly higher at 145 - from time to > time slight drops to 135/85 approx. Range now appears to be 140/90. > Creatinine now at around 110 - just ten below the normal upper limit. > > Gynecomastia still happening and so being switched to 50 mg Inspra > after the Xmas break. 50 mg appears to be available in Oz but as > not subsidised will be very expensive. Will still be on amiloride > 10 mg with twice weekly blood tests. Information about headaches > and depression from other folks have all been closely and > gratefully taken on board - including earlier comments that with > Inspra, you need to take it into your system slowly. > > Also I now have a persistent slight to medium swelling in feet, > ankles and lower legs - have not been on Zanidip or Norvasc for > almost a month now, so not sure where this is coming from - maybe > related to kidney issues earlier and it has just not cleared up. > > Gets quite bad when I sit at computer for long periods of time. Not > significantly relieved by putting my feet up. > > Any comments or suggestions from people familiar with changing over > from Spiro to Inspra welcome. > > Merry xmas to all > > Kwame > > Stay connected to the people that matter most with a smarter inbox. > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 Do you drink tea that contains licorice? Recently I have come to notice there are lots of variety of teas and many of them contain licorice. On Wed, Dec 24, 2008 at 10:18 AM, kwame mfodwo <kmfodwo@...> wrote: > yes - African from Ghana > > ________________________________ > From: kwame mfodwo <kmfodwo@... <kmfodwo%40.au>> > hyperaldosteronism <hyperaldosteronism%40> > Sent: Thursday, 25 December, 2008 5:12:45 AM > > Subject: Re: My events so far > > have not been on CCBs for almost six weeks or more now. Swelling not > related to CC although may have carried it over a bit from when on Zanidip > which gave me much less swelling than Norvasc. Stopped Norvasc probably 4 > months ago. No specific tests done on renal damage. Creatinine went up to > 136, came down to 120-126 then now down to around 110. > > ____________ _________ _________ __ > From: Clarence Grim <lowerbp2mac (DOT) com> > hyperaldosteronism > Sent: Tuesday, 23 December, 2008 2:43:54 AM > Subject: Re: [hyperaldosteronism ] My events so far > > The swelling is most likely due to Norvasc and eating too much salt. > > You should be able to taper it as Inspra kicks in. > > Again DASHing potentiates all BP Rx esp in PA. > > I forgot if you are of African descent (well recently as all of us > are of African descent). Is so the AASK study suggested that Norvasc > may not be the best choice if you have renal damage. > > Any protein in urine? > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > of potassium as I can get up to and no added salt. Was also on 20 > > mg Zanidip but does not appear to be really contributing very much. > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > time slight drops to 135/85 approx. Range now appears to be 140/90. > > Creatinine now at around 110 - just ten below the normal upper limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as > > not subsidised will be very expensive. Will still be on amiloride > > 10 mg with twice weekly blood tests. Information about headaches > > and depression from other folks have all been closely and > > gratefully taken on board - including earlier comments that with > > Inspra, you need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > Stay connected to the people that matter most with a smarter inbox. > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 I would think we need to add an " Effects of DASHing in Conn's stories " to our files. This would be a brief personal story about how DASHing affected your ability to control BP and K. Were medications able to be stepped down? etc. Comments from the group. I think we can make a major contribution here. Clarence Grim lowerbp2@... On Dec 24, 2008, at 12:09 PM, kwame mfodwo wrote: > yes - dashing has helped greatly > > ________________________________ > From: Lowerbp2 <lowerbp2@...> > " hyperaldosteronism " > <hyperaldosteronism > > Sent: Monday, 22 December, 2008 2:53:10 PM > Subject: Re: Re: My events so far > > Do you think DASHing has helped > > Sent from my iPhone > > CE Grim MD > > On Dec 21, 2008, at 4:09 PM, bigdogdkiedrow <bigdogdkiedrow@ > ..com> > wrote: > > > I switched over from Spiro to Inspra several years ago. The biggest > > issue I had was the cost. However, the " bad " side-effects of the > > spiro went away. Gynecomastia went away. Had to play with the dosage > > to get things right as far as BP & electrolytes go. Headaches did > not > > seem to change any with the switch over. Depression ... not really > > sure as things change sometimes on a daily basis. > > > > ~Dave K > > > > > > > > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > > Now  on 10 mg amiloride and 50 mg spiro per day with as high > > levels of potassium as I can get up to and no added salt. Was > also on > > 20 mg Zanidip but does not appear to be really contributing very > > much. BP around 140/90 - sometimes slightly higher at 145 - from > time > > to time slight drops to 135/85 approx. Range now appears to be > > 140/90. Creatinine now at around 110 - just ten below the normal > > upper limit. > > > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as > not > > subsidised will be very expensive. Will still be on amiloride 10 mg > > with twice weekly blood tests. Information about headaches and > > depression from other folks have all been closely and gratefully > > taken on board - including earlier comments that with Inspra, you > > need to take it into your system slowly. > > > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > > > Gets quite bad when I sit at computer for long periods of time. > Not > > significantly relieved by putting my feet up. > > > > > > Any comments or suggestions from people familiar with changing > over > > from Spiro to Inspra welcome. > > > > > > Merry xmas to all > > > > > > Kwame > > > > > > > > > Stay connected to the people that matter most with a smarter > > inbox. Take a look http://au.docs. / mail/smarterinbo x > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 If not on a CCB and no varicose vein problem (VV) then swelling likely do to eating more salt than you can get rid of. After the holidays you may want to do the 14 day DASH diet exactly as in book to see if it goes away. Clarence Grim lowerbp2@...  On Dec 24, 2008, at 12:12 PM, kwame mfodwo wrote: > have not been on CCBs for almost six weeks or more now. Swelling > not related to CC although may have carried it over a bit from when > on Zanidip which gave me much less swelling than Norvasc. Stopped > Norvasc probably 4 months ago. No specific tests done on renal > damage. Creatinine went up to 136, came down to 120-126 then now > down to around 110. > > ________________________________ > From: Clarence Grim <lowerbp2@...> > hyperaldosteronism > Sent: Tuesday, 23 December, 2008 2:43:54 AM > Subject: Re: My events so far > > The swelling is most likely due to Norvasc and eating too much salt. > > You should be able to taper it as Inspra kicks in. > > Again DASHing potentiates all BP Rx esp in PA. > > I forgot if you are of African descent (well recently as all of us > are of African descent). Is so the AASK study suggested that Norvasc > may not be the best choice if you have renal damage. > > Any protein in urine? > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > of potassium as I can get up to and no added salt. Was also on 20 > > mg Zanidip but does not appear to be really contributing very much. > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > time slight drops to 135/85 approx. Range now appears to be 140/90. > > Creatinine now at around 110 - just ten below the normal upper > limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as > > not subsidised will be very expensive. Will still be on amiloride > > 10 mg with twice weekly blood tests. Information about headaches > > and depression from other folks have all been closely and > > gratefully taken on board - including earlier comments that with > > Inspra, you need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > Stay connected to the people that matter most with a smarter inbox. > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 Licorice effect would lead to low renin AND low aldo. You could pubmed licorice tea to see if any reports on HTN due to this. Many other sources of licorice have been reported to do so. Chewing tobacco, GI flavored meds, candy, maybe even toothpicks one or our folks here from a year or more ago. Clarence Grim lowerbp2@... On Dec 24, 2008, at 12:36 PM, Farah Rahbar wrote: > Do you drink tea that contains licorice? Recently I have come to > notice > there are lots of variety of teas and many of them contain licorice. > > On Wed, Dec 24, 2008 at 10:18 AM, kwame mfodwo > <kmfodwo@...> wrote: > > > yes - African from Ghana > > > > ________________________________ > > From: kwame mfodwo <kmfodwo@... <kmfodwo%40.au>> > > hyperaldosteronism <hyperaldosteronism% > 40> > > Sent: Thursday, 25 December, 2008 5:12:45 AM > > > > Subject: Re: My events so far > > > > have not been on CCBs for almost six weeks or more now. Swelling not > > related to CC although may have carried it over a bit from when > on Zanidip > > which gave me much less swelling than Norvasc. Stopped Norvasc > probably 4 > > months ago. No specific tests done on renal damage. Creatinine > went up to > > 136, came down to 120-126 then now down to around 110. > > > > ____________ _________ _________ __ > > From: Clarence Grim <lowerbp2mac (DOT) com> > > hyperaldosteronism > > Sent: Tuesday, 23 December, 2008 2:43:54 AM > > Subject: Re: [hyperaldosteronism ] My events so far > > > > The swelling is most likely due to Norvasc and eating too much salt. > > > > You should be able to taper it as Inspra kicks in. > > > > Again DASHing potentiates all BP Rx esp in PA. > > > > I forgot if you are of African descent (well recently as all of us > > are of African descent). Is so the AASK study suggested that Norvasc > > may not be the best choice if you have renal damage. > > > > Any protein in urine? > > > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > > > Recently had a slight kidney failure problem going up to 136 on > > > creatinine after three to four weeks on spiro - 75 mg and > amiloride > > > 20 mg a day > > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > > of potassium as I can get up to and no added salt. Was also on 20 > > > mg Zanidip but does not appear to be really contributing very > much. > > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > > time slight drops to 135/85 approx. Range now appears to be > 140/90. > > > Creatinine now at around 110 - just ten below the normal upper > limit. > > > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > > after the Xmas break. 50 mg appears to be available in Oz but as > > > not subsidised will be very expensive. Will still be on amiloride > > > 10 mg with twice weekly blood tests. Information about headaches > > > and depression from other folks have all been closely and > > > gratefully taken on board - including earlier comments that with > > > Inspra, you need to take it into your system slowly. > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > almost a month now, so not sure where this is coming from - maybe > > > related to kidney issues earlier and it has just not cleared up. > > > > > > Gets quite bad when I sit at computer for long periods of time. > Not > > > significantly relieved by putting my feet up. > > > > > > Any comments or suggestions from people familiar with changing > over > > > from Spiro to Inspra welcome. > > > > > > Merry xmas to all > > > > > > Kwame > > > > > > Stay connected to the people that matter most with a smarter > inbox. > > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 Good. Our data suggests that one needs completely different renin and aldo cutoffs for African Americans than for French Canadians. Most labs don't have normal data on those of African Descent. Clarence Grim lowerbp2@... On Dec 24, 2008, at 12:18 PM, kwame mfodwo wrote: > yes - African from Ghana > > ________________________________ > From: kwame mfodwo <kmfodwo@...> > hyperaldosteronism > Sent: Thursday, 25 December, 2008 5:12:45 AM > Subject: Re: My events so far > > have not been on CCBs for almost six weeks or more now. Swelling > not related to CC although may have carried it over a bit from when > on Zanidip which gave me much less swelling than Norvasc. Stopped > Norvasc probably 4 months ago. No specific tests done on renal > damage. Creatinine went up to 136, came down to 120-126 then now > down to around 110. > > ____________ _________ _________ __ > From: Clarence Grim <lowerbp2mac (DOT) com> > hyperaldosteronism > Sent: Tuesday, 23 December, 2008 2:43:54 AM > Subject: Re: [hyperaldosteronism ] My events so far > > The swelling is most likely due to Norvasc and eating too much salt. > > You should be able to taper it as Inspra kicks in. > > Again DASHing potentiates all BP Rx esp in PA. > > I forgot if you are of African descent (well recently as all of us > are of African descent). Is so the AASK study suggested that Norvasc > may not be the best choice if you have renal damage. > > Any protein in urine? > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > of potassium as I can get up to and no added salt. Was also on 20 > > mg Zanidip but does not appear to be really contributing very much. > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > time slight drops to 135/85 approx. Range now appears to be 140/90. > > Creatinine now at around 110 - just ten below the normal upper > limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as > > not subsidised will be very expensive. Will still be on amiloride > > 10 mg with twice weekly blood tests. Information about headaches > > and depression from other folks have all been closely and > > gratefully taken on board - including earlier comments that with > > Inspra, you need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > Stay connected to the people that matter most with a smarter inbox. > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 Where can we get the book and what's the title Dr. Grim - btw - Merry Christmas from New Zealand. Sue ________________________________ From: Clarence Grim <lowerbp2@...> hyperaldosteronism Sent: Thursday, 25 December, 2008 7:46:27 AM Subject: Re: My events so far If not on a CCB and no varicose vein problem (VV) then swelling likely do to eating more salt than you can get rid of. After the holidays you may want to do the 14 day DASH diet exactly as in book to see if it goes away. Clarence Grim lowerbp2mac (DOT) com  On Dec 24, 2008, at 12:12 PM, kwame mfodwo wrote: > have not been on CCBs for almost six weeks or more now. Swelling > not related to CC although may have carried it over a bit from when > on Zanidip which gave me much less swelling than Norvasc. Stopped > Norvasc probably 4 months ago. No specific tests done on renal > damage. Creatinine went up to 136, came down to 120-126 then now > down to around 110. > > ____________ _________ _________ __ > From: Clarence Grim <lowerbp2mac (DOT) com> > hyperaldosteronism > Sent: Tuesday, 23 December, 2008 2:43:54 AM > Subject: Re: [hyperaldosteronism ] My events so far > > The swelling is most likely due to Norvasc and eating too much salt. > > You should be able to taper it as Inspra kicks in. > > Again DASHing potentiates all BP Rx esp in PA. > > I forgot if you are of African descent (well recently as all of us > are of African descent). Is so the AASK study suggested that Norvasc > may not be the best choice if you have renal damage. > > Any protein in urine? > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > Recently had a slight kidney failure problem going up to 136 on > > creatinine after three to four weeks on spiro - 75 mg and amiloride > > 20 mg a day > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > of potassium as I can get up to and no added salt. Was also on 20 > > mg Zanidip but does not appear to be really contributing very much. > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > time slight drops to 135/85 approx. Range now appears to be 140/90. > > Creatinine now at around 110 - just ten below the normal upper > limit. > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > after the Xmas break. 50 mg appears to be available in Oz but as > > not subsidised will be very expensive. Will still be on amiloride > > 10 mg with twice weekly blood tests. Information about headaches > > and depression from other folks have all been closely and > > gratefully taken on board - including earlier comments that with > > Inspra, you need to take it into your system slowly. > > > > Also I now have a persistent slight to medium swelling in feet, > > ankles and lower legs - have not been on Zanidip or Norvasc for > > almost a month now, so not sure where this is coming from - maybe > > related to kidney issues earlier and it has just not cleared up. > > > > Gets quite bad when I sit at computer for long periods of time. Not > > significantly relieved by putting my feet up. > > > > Any comments or suggestions from people familiar with changing over > > from Spiro to Inspra welcome. > > > > Merry xmas to all > > > > Kwame > > > > Stay connected to the people that matter most with a smarter inbox. > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2008 Report Share Posted December 24, 2008 CG may have other suggestions, but I rely on the DASH book at NIH ... google nih.gov.nhlbi. ======================================================================== ====== On Dec 24, 2008, at 10:38 PM, marysue hopper wrote: > Where can we get the book and what's the title Dr. Grim - btw - Merry > Christmas from New Zealand. > Sue > > ________________________________ > From: Clarence Grim <lowerbp2@...> > hyperaldosteronism > Sent: Thursday, 25 December, 2008 7:46:27 AM > Subject: Re: My events so far > > If not on a CCB and no varicose vein problem (VV) then swelling > likely do to eating more salt than you can get rid of. > > After the holidays you may want to do the 14 day DASH diet exactly > as in book to see if it goes away. > > Clarence Grim > lowerbp2mac (DOT) com > > > > On Dec 24, 2008, at 12:12 PM, kwame mfodwo wrote: > > > have not been on CCBs for almost six weeks or more now. Swelling > > not related to CC although may have carried it over a bit from when > > on Zanidip which gave me much less swelling than Norvasc. Stopped > > Norvasc probably 4 months ago. No specific tests done on renal > > damage. Creatinine went up to 136, came down to 120-126 then now > > down to around 110. > > > > ____________ _________ _________ __ > > From: Clarence Grim <lowerbp2mac (DOT) com> > > hyperaldosteronism > > Sent: Tuesday, 23 December, 2008 2:43:54 AM > > Subject: Re: [hyperaldosteronism ] My events so far > > > > The swelling is most likely due to Norvasc and eating too much salt. > > > > You should be able to taper it as Inspra kicks in. > > > > Again DASHing potentiates all BP Rx esp in PA. > > > > I forgot if you are of African descent (well recently as all of us > > are of African descent). Is so the AASK study suggested that Norvasc > > may not be the best choice if you have renal damage. > > > > Any protein in urine? > > > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > > > Recently had a slight kidney failure problem going up to 136 on > > > creatinine after three to four weeks on spiro - 75 mg and > amiloride > > > 20 mg a day > > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > > of potassium as I can get up to and no added salt. Was also on 20 > > > mg Zanidip but does not appear to be really contributing very > much. > > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > > time slight drops to 135/85 approx. Range now appears to be > 140/90. > > > Creatinine now at around 110 - just ten below the normal upper > > limit. > > > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > > after the Xmas break. 50 mg appears to be available in Oz but as > > > not subsidised will be very expensive. Will still be on amiloride > > > 10 mg with twice weekly blood tests. Information about headaches > > > and depression from other folks have all been closely and > > > gratefully taken on board - including earlier comments that with > > > Inspra, you need to take it into your system slowly. > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > almost a month now, so not sure where this is coming from - maybe > > > related to kidney issues earlier and it has just not cleared up. > > > > > > Gets quite bad when I sit at computer for long periods of time. > Not > > > significantly relieved by putting my feet up. > > > > > > Any comments or suggestions from people familiar with changing > over > > > from Spiro to Inspra welcome. > > > > > > Merry xmas to all > > > > > > Kwame > > > > > > Stay connected to the people that matter most with a smarter > inbox. > > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 25, 2008 Report Share Posted December 25, 2008 Thanks you Arthur Sue ________________________________ From: arthur springer <as99@...> hyperaldosteronism Sent: Thursday, 25 December, 2008 5:15:13 PM Subject: Re: My events so far CG may have other suggestions, but I rely on the DASH book at NIH ... google nih.gov.nhlbi. ============ ========= ========= ========= ========= ========= ========= ====== ====== On Dec 24, 2008, at 10:38 PM, marysue hopper wrote: > Where can we get the book and what's the title Dr. Grim - btw - Merry > Christmas from New Zealand. > Sue > > ____________ _________ _________ __ > From: Clarence Grim <lowerbp2mac (DOT) com> > hyperaldosteronism > Sent: Thursday, 25 December, 2008 7:46:27 AM > Subject: Re: [hyperaldosteronism ] My events so far > > If not on a CCB and no varicose vein problem (VV) then swelling > likely do to eating more salt than you can get rid of. > > After the holidays you may want to do the 14 day DASH diet exactly > as in book to see if it goes away. > > Clarence Grim > lowerbp2mac (DOT) com > > > > On Dec 24, 2008, at 12:12 PM, kwame mfodwo wrote: > > > have not been on CCBs for almost six weeks or more now. Swelling > > not related to CC although may have carried it over a bit from when > > on Zanidip which gave me much less swelling than Norvasc. Stopped > > Norvasc probably 4 months ago. No specific tests done on renal > > damage. Creatinine went up to 136, came down to 120-126 then now > > down to around 110. > > > > ____________ _________ _________ __ > > From: Clarence Grim <lowerbp2mac (DOT) com> > > hyperaldosteronism > > Sent: Tuesday, 23 December, 2008 2:43:54 AM > > Subject: Re: [hyperaldosteronism ] My events so far > > > > The swelling is most likely due to Norvasc and eating too much salt. > > > > You should be able to taper it as Inspra kicks in. > > > > Again DASHing potentiates all BP Rx esp in PA. > > > > I forgot if you are of African descent (well recently as all of us > > are of African descent). Is so the AASK study suggested that Norvasc > > may not be the best choice if you have renal damage. > > > > Any protein in urine? > > > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > > > Recently had a slight kidney failure problem going up to 136 on > > > creatinine after three to four weeks on spiro - 75 mg and > amiloride > > > 20 mg a day > > > Now on 10 mg amiloride and 50 mg spiro per day with as high levels > > > of potassium as I can get up to and no added salt. Was also on 20 > > > mg Zanidip but does not appear to be really contributing very > much. > > > BP around 140/90 - sometimes slightly higher at 145 - from time to > > > time slight drops to 135/85 approx. Range now appears to be > 140/90. > > > Creatinine now at around 110 - just ten below the normal upper > > limit. > > > > > > Gynecomastia still happening and so being switched to 50 mg Inspra > > > after the Xmas break. 50 mg appears to be available in Oz but as > > > not subsidised will be very expensive. Will still be on amiloride > > > 10 mg with twice weekly blood tests. Information about headaches > > > and depression from other folks have all been closely and > > > gratefully taken on board - including earlier comments that with > > > Inspra, you need to take it into your system slowly. > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > almost a month now, so not sure where this is coming from - maybe > > > related to kidney issues earlier and it has just not cleared up. > > > > > > Gets quite bad when I sit at computer for long periods of time. > Not > > > significantly relieved by putting my feet up. > > > > > > Any comments or suggestions from people familiar with changing > over > > > from Spiro to Inspra welcome. > > > > > > Merry xmas to all > > > > > > Kwame > > > > > > Stay connected to the people that matter most with a smarter > inbox. > > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 25, 2008 Report Share Posted December 25, 2008 the NIH site is brief. I recommend the Book by T. et al The DASH diet for Hypertension paperback about 8US online. It details the science behind the diet, the testing that was done and has a 14 day menus to do a DASH test to see if your BP is DASH sensitive. It is written in a lay language. Plus many recipes. Clarence Grim lowerbp2@... On Dec 24, 2008, at 10:15 PM, arthur springer wrote: > CG may have other suggestions, but I rely on the DASH book at NIH ... > google nih.gov.nhlbi. > ====================================================================== > == > ====== > On Dec 24, 2008, at 10:38 PM, marysue hopper wrote: > > > Where can we get the book and what's the title Dr. Grim - btw - > Merry > > Christmas from New Zealand. > > Sue > > > > ________________________________ > > From: Clarence Grim <lowerbp2@...> > > hyperaldosteronism > > Sent: Thursday, 25 December, 2008 7:46:27 AM > > Subject: Re: My events so far > > > > If not on a CCB and no varicose vein problem (VV) then swelling > > likely do to eating more salt than you can get rid of. > > > > After the holidays you may want to do the 14 day DASH diet exactly > > as in book to see if it goes away. > > > > Clarence Grim > > lowerbp2mac (DOT) com > > > > > > > > On Dec 24, 2008, at 12:12 PM, kwame mfodwo wrote: > > > > > have not been on CCBs for almost six weeks or more now. Swelling > > > not related to CC although may have carried it over a bit from > when > > > on Zanidip which gave me much less swelling than Norvasc. Stopped > > > Norvasc probably 4 months ago. No specific tests done on renal > > > damage. Creatinine went up to 136, came down to 120-126 then now > > > down to around 110. > > > > > > ____________ _________ _________ __ > > > From: Clarence Grim <lowerbp2mac (DOT) com> > > > hyperaldosteronism > > > Sent: Tuesday, 23 December, 2008 2:43:54 AM > > > Subject: Re: [hyperaldosteronism ] My events so far > > > > > > The swelling is most likely due to Norvasc and eating too much > salt. > > > > > > You should be able to taper it as Inspra kicks in. > > > > > > Again DASHing potentiates all BP Rx esp in PA. > > > > > > I forgot if you are of African descent (well recently as all of us > > > are of African descent). Is so the AASK study suggested that > Norvasc > > > may not be the best choice if you have renal damage. > > > > > > Any protein in urine? > > > > > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > > > > > Recently had a slight kidney failure problem going up to 136 on > > > > creatinine after three to four weeks on spiro - 75 mg and > > amiloride > > > > 20 mg a day > > > > Now on 10 mg amiloride and 50 mg spiro per day with as high > levels > > > > of potassium as I can get up to and no added salt. Was also > on 20 > > > > mg Zanidip but does not appear to be really contributing very > > much. > > > > BP around 140/90 - sometimes slightly higher at 145 - from > time to > > > > time slight drops to 135/85 approx. Range now appears to be > > 140/90. > > > > Creatinine now at around 110 - just ten below the normal upper > > > limit. > > > > > > > > Gynecomastia still happening and so being switched to 50 mg > Inspra > > > > after the Xmas break. 50 mg appears to be available in Oz but as > > > > not subsidised will be very expensive. Will still be on > amiloride > > > > 10 mg with twice weekly blood tests. Information about headaches > > > > and depression from other folks have all been closely and > > > > gratefully taken on board - including earlier comments that with > > > > Inspra, you need to take it into your system slowly. > > > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > > almost a month now, so not sure where this is coming from - > maybe > > > > related to kidney issues earlier and it has just not cleared up. > > > > > > > > Gets quite bad when I sit at computer for long periods of time. > > Not > > > > significantly relieved by putting my feet up. > > > > > > > > Any comments or suggestions from people familiar with changing > > over > > > > from Spiro to Inspra welcome. > > > > > > > > Merry xmas to all > > > > > > > > Kwame > > > > > > > > Stay connected to the people that matter most with a smarter > > inbox. > > > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 30, 2008 Report Share Posted December 30, 2008 Many thanks. I've ordered one today. Sue ________________________________ From: Clarence Grim <lowerbp2@...> hyperaldosteronism Sent: Friday, 26 December, 2008 7:25:41 AM Subject: Re: My events so far the NIH site is brief. I recommend the Book by T. et al The DASH diet for Hypertension paperback about 8US online. It details the science behind the diet, the testing that was done and has a 14 day menus to do a DASH test to see if your BP is DASH sensitive. It is written in a lay language. Plus many recipes. Clarence Grim lowerbp2mac (DOT) com On Dec 24, 2008, at 10:15 PM, arthur springer wrote: > CG may have other suggestions, but I rely on the DASH book at NIH ... > google nih.gov.nhlbi. > ============ ========= ========= ========= ========= ========= ========= ==== > == > ====== > On Dec 24, 2008, at 10:38 PM, marysue hopper wrote: > > > Where can we get the book and what's the title Dr. Grim - btw - > Merry > > Christmas from New Zealand. > > Sue > > > > ____________ _________ _________ __ > > From: Clarence Grim <lowerbp2mac (DOT) com> > > hyperaldosteronism > > Sent: Thursday, 25 December, 2008 7:46:27 AM > > Subject: Re: [hyperaldosteronism ] My events so far > > > > If not on a CCB and no varicose vein problem (VV) then swelling > > likely do to eating more salt than you can get rid of. > > > > After the holidays you may want to do the 14 day DASH diet exactly > > as in book to see if it goes away. > > > > Clarence Grim > > lowerbp2mac (DOT) com > > > > > > > > On Dec 24, 2008, at 12:12 PM, kwame mfodwo wrote: > > > > > have not been on CCBs for almost six weeks or more now. Swelling > > > not related to CC although may have carried it over a bit from > when > > > on Zanidip which gave me much less swelling than Norvasc. Stopped > > > Norvasc probably 4 months ago. No specific tests done on renal > > > damage. Creatinine went up to 136, came down to 120-126 then now > > > down to around 110. > > > > > > ____________ _________ _________ __ > > > From: Clarence Grim <lowerbp2mac (DOT) com> > > > hyperaldosteronism > > > Sent: Tuesday, 23 December, 2008 2:43:54 AM > > > Subject: Re: [hyperaldosteronism ] My events so far > > > > > > The swelling is most likely due to Norvasc and eating too much > salt. > > > > > > You should be able to taper it as Inspra kicks in. > > > > > > Again DASHing potentiates all BP Rx esp in PA. > > > > > > I forgot if you are of African descent (well recently as all of us > > > are of African descent). Is so the AASK study suggested that > Norvasc > > > may not be the best choice if you have renal damage. > > > > > > Any protein in urine? > > > > > > On Dec 21, 2008, at 1:28 AM, kwame mfodwo wrote: > > > > > > > Recently had a slight kidney failure problem going up to 136 on > > > > creatinine after three to four weeks on spiro - 75 mg and > > amiloride > > > > 20 mg a day > > > > Now on 10 mg amiloride and 50 mg spiro per day with as high > levels > > > > of potassium as I can get up to and no added salt. Was also > on 20 > > > > mg Zanidip but does not appear to be really contributing very > > much. > > > > BP around 140/90 - sometimes slightly higher at 145 - from > time to > > > > time slight drops to 135/85 approx. Range now appears to be > > 140/90. > > > > Creatinine now at around 110 - just ten below the normal upper > > > limit. > > > > > > > > Gynecomastia still happening and so being switched to 50 mg > Inspra > > > > after the Xmas break. 50 mg appears to be available in Oz but as > > > > not subsidised will be very expensive. Will still be on > amiloride > > > > 10 mg with twice weekly blood tests. Information about headaches > > > > and depression from other folks have all been closely and > > > > gratefully taken on board - including earlier comments that with > > > > Inspra, you need to take it into your system slowly. > > > > > > > > Also I now have a persistent slight to medium swelling in feet, > > > > ankles and lower legs - have not been on Zanidip or Norvasc for > > > > almost a month now, so not sure where this is coming from - > maybe > > > > related to kidney issues earlier and it has just not cleared up. > > > > > > > > Gets quite bad when I sit at computer for long periods of time. > > Not > > > > significantly relieved by putting my feet up. > > > > > > > > Any comments or suggestions from people familiar with changing > > over > > > > from Spiro to Inspra welcome. > > > > > > > > Merry xmas to all > > > > > > > > Kwame > > > > > > > > Stay connected to the people that matter most with a smarter > > inbox. > > > > Take a lookhttp://au. docs.. com/mail/ smarterinbox > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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