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[Fwd: Re: Reducing Spiro]

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The Endocrine Society Guidelines recommend ACTH and I think Prof

Gordon was part of that report.

Are they using spiro + other drugs? Only 50 is not enough in many

here in the US. Do they also recommend the DASH?

If it is not in our files you can get a copy by googling it I think.

Clarence Grim BS, MS, MD

Clinical Professor of Medicine

Medical College of Wisconsin

Senior Consultant to Shared Care Research and Education Consulting, Inc.

Specializing in Difficult to control high blood pressure.

On Dec 29, 2008, at 5:11 AM, Carol Christie wrote:

>

>

> --- Reducing Spiro

> > hyperaldosteronism

> > <mailto:hyperaldosteronism%40>

> > Date: Saturday, December 27, 2008, 10:04 PM

> >

> > As I will be having another AVS I have to gradually reduce spiro

> from

> > 75mg a day. I am now taking 50mg. I feel like I've been hit by a

> > truck...feel as bad as I used to feel on 25mg per day. Weakness,

> back

> > pain, fuzzy headed, quick to get out of breath. The difference is

> > striking.

> > Carol

> >

> >

> >

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I have uploaded the Endocrine Society's guidelines for PA. The list will

get a notice. Authors include Stowasser M (Australia) and Young WF Jr (Mayo

Clinic).

Here is a response that takes exception to some of the guidelines:

http://jcem.endojournals.org/cgi/eletters/93/9/3266

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Carol Christie

I wonder if there is some

generally accepted protocol. The other big variable seems to be related

to spiro dosage. At Greenslopes Hypertension Unit (Brisbane) (Profs

Gordon and Stowasser) there seems to be a reluctance to prescribe much

over 50mg a day.

Carol.

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where is it? no access to journal comment for non-subscribers.

>

> I have uploaded the Endocrine Society's guidelines for PA. The list

will

> get a notice. Authors include Stowasser M (Australia) and Young WF

Jr (Mayo

> Clinic).

>

> Here is a response that takes exception to some of the guidelines:

> http://jcem.endojournals.org/cgi/eletters/93/9/3266

>

> Val

>

> From: hyperaldosteronism

> [mailto:hyperaldosteronism ] On Behalf Of Carol Christie

>

> I wonder if there is some

> generally accepted protocol. The other big variable seems to be related

> to spiro dosage. At Greenslopes Hypertension Unit (Brisbane) (Profs

> Gordon and Stowasser) there seems to be a reluctance to prescribe much

> over 50mg a day.

> Carol.

>

>

>

>

>

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Atacand is usually useless in PA as there is no renin (AII) to block.

Zanidip CCB makes feet swell. Not available in US.

Good question to ask why they use so little. If you can control BP on

one drug that is always better IMHO.

Clarence Grim

lowerbp2@...

On Dec 29, 2008, at 2:33 PM, megra0409 wrote:

> Hi Carol,

>

> Like the Doctors at Greenslopes in Queensland, my Renal Physician

> here in

> Sydney also wants to maintain the lowest dose possible for me, and

> I have

> had serious ups and downs as we try to find that dosage. I find it

> interesting that it appears fellow suffers in the US are taking

> much higher

> doses of Sprio than we are, and I am interested in why that is

> occurring.

> My Renal doctor adds other hypertension drugs such as Atacand and

> Zanidip to

> my current 37.5 mg daily dosage of Spiro to control my BP, and it

> seems to

> be doing the job, but I still suffer long periods of extreme

> fatigue, muscle

> cramping, headaches etc. I am currently on three weeks leave and am

> happy

> to report that I am feeling better than I was, but I go back to

> work on 7/1

> and am already getting anxious about returning to that terrible

> status I was

> pre-holiday.

>

> I am pondering whether a higher dose would be better, and would be

> interested in hearing what the group thinks.

>

> Best wishes to all for the New Year - let's hope things improve.

>

>

>

> From: hyperaldosteronism

> [mailto:hyperaldosteronism ] On Behalf Of Carol

> Christie

> Sent: Tuesday, 30 December 2008 12:11 AM

> hyperaldosteronism

> Subject: [Fwd: Re: Reducing Spiro]

>

> --- Reducing Spiro

> > hyperaldosteronism

> <mailto:hyperaldosteronism%40>

> > <mailto:hyperaldosteronism%40>

> > Date: Saturday, December 27, 2008, 10:04 PM

> >

> > As I will be having another AVS I have to gradually reduce spiro

> from

> > 75mg a day. I am now taking 50mg. I feel like I've been hit by a

> > truck...feel as bad as I used to feel on 25mg per day. Weakness,

> back

> > pain, fuzzy headed, quick to get out of breath. The difference is

> > striking.

> > Carol

> >

> >

> >

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