Guest guest Posted February 29, 2000 Report Share Posted February 29, 2000 In a message dated 2/29/00 3:26:08 PM, polyvios@... writes: << WHAT IS TYLENOL? >> Tylenol is a brand name for acetaminophen. It is for pain. No prescription. Your friend could bring you some, if you don't have it in Greece. Kat Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 26, 2008 Report Share Posted March 26, 2008 I was told tylenol was not OK by Dr. Cortes but have read other places it is OK if not exceeding the recommended dosage. My new Onc told me I could take excedrin. I take Aleve if I have pain but this is probably only once every 2 weeks (lucky me). regards, Donna > Okay, I'm reading a lot of responses that say NO on Tylenol and YES to IBprofen?? > I was told the opposite by the doc. > > Ugh! What's real? > Tammy > > > > > > > a (Bobby) Doyle > Brecksville, Ohio, USA > DX 05/1995 > 02/2000 - Gleevec Trial/OHSU > 06/2002 - Gleevec/Trisenox Trial/OHSU > 06/2003 - Gleevec/Zarnestra Trial/OHSU > 04/2004 - Sprycel Trial/MDACC, CCR in 10 months > #840 - Zavie's Zero Club > 09/2006 - out of CCR > SKYPE: RCD1929 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 26, 2008 Report Share Posted March 26, 2008 The issue with Tylenol is that when it's taken with Gleevec, your serum level of Tylenol can go much higher than it should (because Gleevec inhibits the glucurinidation of the Tylenol) so a dose of 500mg could potentially be double that. Some doctors say to avoid Tylenol all together because of the unpredictable drug level while others say that as long as you don't take too much of it, you should be ok. My personal feeling is that if you can take an alternative (such as Advil) then why risk overloading your liver by using Tylenol. If you can't take the other drugs for some reason, then talk to your doctor about how much Tylenol is safe for you to take. Tracey Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 26, 2008 Report Share Posted March 26, 2008 For once I am going to differ a bit with Tracey. From what I have read/heard tylenol (=aceminatophen) is toxic for the liver above the recommended dose, even without gleevec, and should never be overdosed (ibuprofen can). As gleevec is also potentially toxic for the liver the combination even with a normal dose of tylenol could be dangerous and liver should be monitored. The only toxicity related fatality they had on the early gleevec trials was I think somebody who had liver failure taking a full dose of tylenol for a long time. The 4 drs I saw (2 cml specialists) said that as long as liver counts are normal I could take some tylenol but I should not go over half the daily limit. If it's not enough then to alternate with ibuprophen or aspirin (if platelets are ok). But aceminatophen has advantages on both ibuprophen and aspirin and the drs told me to try that first. Marcos. On Wed, Mar 26, 2008 at 11:58 AM, Tracey <traceyincanada@...> wrote: > > > > > The issue with Tylenol is that when it's taken with Gleevec, your serum > level of Tylenol can go much higher than it should (because Gleevec > inhibits the glucurinidation of the Tylenol) so a dose of 500mg could > potentially be double that. > > Some doctors say to avoid Tylenol all together because of the > unpredictable drug level while others say that as long as you don't > take too much of it, you should be ok. > > My personal feeling is that if you can take an alternative (such as > Advil) then why risk overloading your liver by using Tylenol. If you > can't take the other drugs for some reason, then talk to your doctor > about how much Tylenol is safe for you to take. > > Tracey > > -- Marcos Perreau Guimaraes Suppes Brain Lab Ventura Hall - CSLI Stanford University 220 Panama street Stanford CA 94305-4101 650 614 2305 650 630 5015 (cell) marcospg@... montereyunderwater@... www.stanford.edu/~marcospg/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2008 Report Share Posted March 27, 2008 Hi All. I am going to second lin. I take a heart medicine that adds toxsity to to liver, and an asprin a day for blood thinner. In my several discussions with my ONC I always get this same response. Using Tylenol or any other pain reliver containing aceminatophen can cause a problem. The final results of the one person who lost their life due to Tylenol was over-dosing and continued do so for a prolonged time. If I should need to take a pain reliever to start with Ibuprofen as directed by the anufacturer. If that fails to releive the pain, you can use the additional benifits of Tylenol or other aceminatophen product using the recommended dosage for a short time. If the pain still exists then see me and we will invistgate a pain management system that will work without stressing the liver. H. dxd 2/03 400mg Gleevec 3/03 PCR negatuve 11/03 QPCR undetectible 11/04 QT-PCR .01 1/05 Iron Deficient Anemia 11/06 QR-PCR .012 11/07 transfusions thru 5/07 Gleevec Vacation 8 mths 6/07 - 1/08 WBC normal, HGB gained to 11.7 QT-PCR 1/08 .071 400 MG Gleevec 1/08 PCR negative 2/08 Awaiting results of QT-PCR 3/08 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 27, 2008 Report Share Posted March 27, 2008 OOPS! Sorry Lynn I lost your lost name when I attemted to shorten my message. H. > > > Quote Link to comment Share on other sites More sharing options...
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