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Several years ago I expounded at length on this list about the benefits of a

paleolithic diet. A paleo-diet prohibits soy because one cannot consume soy in

its raw state. Unprocessed soy causes terrible digestion problems.

On this paleo view of proper diet, which I endorse, one ought not consume

anything that one cannot consume raw.

Note that I do mean to say that I believe one ought consume only cooked foods. I

have no problem with cooked foods. I mean only that one ought to avoid foods

that one cannot consume raw.

As such, a paleo diet includes only meat, fish, fowl, eggs, vegetables, fruits

and nuts. As a legume, soy does not qualify.

In the years since I advocated this paleo-diet idea here on this list, quite a

lot of research has turned up to support the hypothesis.

Anyway I thought I should chime in to state my vote in favor of the idea that

soy consumption does not seem like a good idea.

That's the least I can do. After all I own this discussion list. I'm the guy at

the bottom of each message who says, " This forum is for discussion of health

related subjects but under no circumstances [blah blah blah]. "

Sorry about my absence in the last couple of years. I have a busy life.

-gts

> From: stardora@... <stardora@...>

> Subject: Compounds From Soy Affect Brain And Reproductive

Development

> Undisclosed-Recipient@...

> Cc: " AAR " <AntiAgingResearch >, Longevity

> Date: Friday, August 1, 2008, 12:46 PM

> Compounds From Soy Affect Brain And Reproductive Development

> http://www.sciencedaily.com/releases/2008/07/080731140030.htm

> ScienceDaily (Aug. 1, 2008) - Two hormone-like compounds

> linked to the consumption of soy-based foods can cause

> irreversible changes in the structure of the brain,

> resulting in early-onset puberty and symptoms of advanced

> menopause in research animals, according to a new study by

> researchers at North Carolina State University.

>

> The study is a breakthrough in determining how these

> compounds can cause reproductive health problems, as well as

> in providing a key building block for how to treat these

> problems.

>

> The study is the first to show that the actual physical

> organization of a region of the brain that is important for

> female reproduction can be significantly altered by exposure

> to phytoestrogens - or plant-produced chemicals that mimic

> hormones - during development. Specifically, the study finds

> that the compounds alter the sex-specific organization of

> the hypothalamus - a brain region that is essential to the

> regulation of puberty and ovulation. The study also shows

> that the phytoestrogens could cause long-term effects on the

> female reproductive system.

>

> While the study examined the impact of these compounds on

> laboratory rats, neurotoxicologist Dr. Patisaul -

> who co-authored the study - says the affected

> " circuitry " of the brain is similar in both rats

> and humans. Patisaul is an assistant professor in NC

> State's Department of Zoology. Her co-author is

> Bateman, a doctoral student in the department.

>

> Patisaul says this finding is extremely important because,

> while the changes in brain structure cannot be reversed,

> " if you understand what is broken, you may be able to

> treat it. " Patisaul says she is in the process of

> evaluating the effects of these compounds on the ovaries

> themselves.

>

> Patisaul says that this study is also " a step towards

> ascertaining the effects of phytoestrogens on developing

> fetuses and newborns. " Patisaul adds that these

> phytoestrogenic compounds cross the placental barrier in

> humans and that, while many people are concerned about the

> effects of man-made compounds on human health, it is

> important to note that some naturally occurring substances

> can have similar effects.

>

> In the study, which will be published in an upcoming issue

> of Neurotoxicology, the researchers exposed newborn rats to

> physiologically relevant doses of the phytoestrogens

> genistein and equol, and then looked at reproductive health

> markers in the rats throughout their adulthood. The neonatal

> stage of development in rats is comparable to the latter

> stages of pregnancy for humans, Patisaul says. Genistein is

> a phytoestrogen that is found in various plants, including

> soybeans and soy-based foods. Equol is a hormone-like

> compound that is formed when bacteria found in the digestive

> system metabolize another phytoestrogen. However, only

> approximately a third of humans have the necessary bacteria

> to produce equol.

>

> The study shows that both genistein and equol result in the

> early disruption of the rats' estrus cycle - which would

> be corollary to early onset of menopause in a human. The

> study also showed that genistein caused the early onset of

> puberty. The disruption of the estrus cycle could stem from

> problems with the brain or the ovaries, so the researchers

> decided to determine if the compounds had any effect on

> brain development or function.

>

> Patisaul explains that the brains of both female rats and

> female humans have a region that regulates ovulation.

> " That part of the brain, " Patisaul says, " is

> organized by hormones during development - which is the

> neonatal stage for rats and during gestation for

> humans. " Patisaul says the new study shows that the

> female brain is " critically sensitive " to

> genistein and equol during this crucial stage of development

> - and that this may indicate that the brain is also

> especially sensitive during this period to all

> phytoestrogens and possibly other man-made chemicals, such

> as bisphenol-A.

>

>

>

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OK, Gordon. That means no rhubarb, right? A lot of my friends would

be upset with this exclusion.

Gordon Swobe wrote:

> Several years ago I expounded at length on this list about the

> benefits of a paleolithic diet. A paleo-diet prohibits soy because one

> cannot consume soy in its raw state. Unprocessed soy causes terrible

> digestion problems.

>

> On this paleo view of proper diet, which I endorse, one ought not

> consume anything that one cannot consume raw.

>

> Note that I do mean to say that I believe one ought consume only

> cooked foods. I have no problem with cooked foods. I mean only that

> one ought to avoid foods that one cannot consume raw.

>

> -gts

>

>

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