RE: FW: [Chirolist-CA] Statins and diabetes

[Guest guest]

On this topic, attached is a JAMA study which is a meta-analysis of 5 studies of intensive Statin use, finding increased diabetes in women. To bad, as we all know heart disease is caused by a statin deficiency, right? Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724oregonchiro@...; From: caughlindrc@...Date: Mon, 30 Jan 2012 16:44:25 +0000Subject: FW: [Chirolist-CA] Statins and diabetes

FYI from another list serve.Dr. A Caughlin DC CAC155 NW 1st Ave Day, Or. 97845 office 541-575-1063 fax 541-575-5554> > ONLINE FIRST> Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the> Women's Health Initiative> > Annie L. Culver, BPharm; Ira S. Ockene, MD; Raji Balasubramanian, ScD;> Barbara C. Olendzki, RD, MPH; Deidre M. Sepavich, MBA;Wactawski-Wende,> PhD; JoAnn E. Manson, MD, DrPH; Yongxia Qiao, MD; Simin Liu, MD, ScD; Philip> A. Merriam, MSPH; Rahilly-Tierny, MD, MPH; Fridtjof , PhD;> S. Berger, MD, MS; Judith K. Ockene, PhD, MEd, MA; J. Curb,> MD;Yunsheng Ma, MD, PhD > > Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625> > Background This study investigates whether the incidence of new-onset> diabetes mellitus (DM) is associated with statin use among postmenopausal> women participating in the Women's Health Initiative (WHI).> > Methods The WHI recruited 161 808 postmenopausal women aged 50 to 79 years> at 40 clinical centers across the United States from 1993 to 1998 with> ongoing follow-up. The current analysis includes data through 2005. Statin> use was captured at enrollment and year 3. Incident DM status was determined> annually from enrollment. proportional hazards models were used to> estimate the risk of DM by statin use, with adjustments for propensity score> and other potential confounding factors. Subgroup analyses by> race/ethnicity, obesity status, and age group were conducted to uncover> effect modification.> > Results This investigation included 153 840 women without DM and no missing> data at baseline. At baseline, 7.04% reported taking statin medication.> There were 10 242 incident cases of self-reported DM over 1 004 466> person-years of follow-up. Statin use at baseline was associated with an> increased risk of DM (hazard ratio

---

, 1.71; 95% CI, 1.61-1.83). This> association remained after adjusting for other potential confounders> (multivariate-adjusted HR, 1.48; 95% CI, 1.38-1.59) and was observed for all> types of statin medications. Subset analyses evaluating the association of> self-reported DM with longitudinal measures of statin use in 125 575 women> confirmed these findings.> > Conclusions Statin medication use in postmenopausal women is associated> with an increased risk for DM. This may be a medication class effect.> Further study by statin type and dose may reveal varying risk levels for> new-onset DM in this population.> > > > > > > > > > ********************************************************************************> "Building Chiropractic Community through enhanced communication."> > To change your preferences or unsubscribe:> http://ww3.chirolists.com/mailman/listinfo/chirolist-ca> email: Chirolist-CA-request@...?subject=unsubscribe> List options tutorial:> http://www.chirolists.com/index.cfm?nid=6> Email filters tutorial:> http://www.chirolists.com/index.cfm?nid=7> *********************************************************************************

1 of 1 File(s)

increased risk of diabetes in high dose statin use in women-JAMA 2011.pdf

[Guest guest]

How about another article pointing out the "benefits" of statins? From the blog of Dr. Briffa (a British MD):Cholesterol-lowering-

Probably the biggest wank in the history of medicine.

A

soon-to-be published article in the journal Atherosclerosis adds to the vast sum of

research contradicting the cholesterol theory of cardiovascular disease.

In this study, researchers tracked 82,380

participants with no known history of cardiovascular disease for an average of

eight years (during the period 1994–2004) as part of the Health Survey for

England. Mean age of the subjects was 55.4 and the male:female ratio was 45:55.

Given

that we’ve been told ad naseum cholesterol causes coronary heart

disease (CHD), you’d expect blood cholesterol to assert itself as a robust risk

factor for heart disease in such a large study. With 82,380 participants

followed for almost a decade, and with 806 and 1346 subsequent deaths from

stroke and CHD deaths, respectively, cholesterol had every opportunity to leave

its allegedly deadly mark.

But it didn’t.

Total cholesterol levels didn’t make a whit of

difference to coronary heart disease risk, and were in fact associated with a

lower risk of stroke[1].

Oops. Bet this study won’t be getting the

extravagant media coverage given to all those shonky Big Pharma-sponsored

statin studies that are prematurely ended whilst the “miracle” drug is still

showing a piddling but “statistically significant” advantage…

So what factors were associated with increased

stroke and heart attack risk?

Only age, smoking, systolic BP, diabetes and

physical activity were predictive of stroke, while age, male gender (get those

iron levels checked fellas…), smoking, systolic blood pressure, HDL

cholesterol, diabetes, BMI, physical activity, CRP, and fibrinogen were

predictive of coronary heart disease.

Bottom line: Don’t smoke, do some regular

exercise, avoid high blood sugar levels, keep a healthy weight, and keep your

serum ferritin between 30-75 (depending on your activity levels). And give

cholesterol-phobia a good swift kick in its fraudulent backside.

References

1. Hamer

M, et al. Comparison of risk factors for fatal stroke and ischemic heart

disease: A prospective follow up of the health survey for England. Atherosclerosis (2011),

doi:10.1016/j.atherosclerosis.2011.08.016 Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724oregonchiro@...; From: caughlindrc@...Date: Mon, 30 Jan 2012 16:44:25 +0000Subject: FW: [Chirolist-CA] Statins and diabetes

FYI from another list serve.Dr. A Caughlin DC CAC155 NW 1st Ave Day, Or. 97845 office 541-575-1063 fax 541-575-5554> > ONLINE FIRST> Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the> Women's Health Initiative> > Annie L. Culver, BPharm; Ira S. Ockene, MD; Raji Balasubramanian, ScD;> Barbara C. Olendzki, RD, MPH; Deidre M. Sepavich, MBA;Wactawski-Wende,> PhD; JoAnn E. Manson, MD, DrPH; Yongxia Qiao, MD; Simin Liu, MD, ScD; Philip> A. Merriam, MSPH; Rahilly-Tierny, MD, MPH; Fridtjof , PhD;> S. Berger, MD, MS; Judith K. Ockene, PhD, MEd, MA; J. Curb,> MD;Yunsheng Ma, MD, PhD > > Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625> > Background This study investigates whether the incidence of new-onset> diabetes mellitus (DM) is associated with statin use among postmenopausal> women participating in the Women's Health Initiative (WHI).> > Methods The WHI recruited 161 808 postmenopausal women aged 50 to 79 years> at 40 clinical centers across the United States from 1993 to 1998 with> ongoing follow-up. The current analysis includes data through 2005. Statin> use was captured at enrollment and year 3. Incident DM status was determined> annually from enrollment. proportional hazards models were used to> estimate the risk of DM by statin use, with adjustments for propensity score> and other potential confounding factors. Subgroup analyses by> race/ethnicity, obesity status, and age group were conducted to uncover> effect modification.> > Results This investigation included 153 840 women without DM and no missing> data at baseline. At baseline, 7.04% reported taking statin medication.> There were 10 242 incident cases of self-reported DM over 1 004 466> person-years of follow-up. Statin use at baseline was associated with an> increased risk of DM (hazard ratio

---

, 1.71; 95% CI, 1.61-1.83). This> association remained after adjusting for other potential confounders> (multivariate-adjusted HR, 1.48; 95% CI, 1.38-1.59) and was observed for all> types of statin medications. Subset analyses evaluating the association of> self-reported DM with longitudinal measures of statin use in 125 575 women> confirmed these findings.> > Conclusions Statin medication use in postmenopausal women is associated> with an increased risk for DM. This may be a medication class effect.> Further study by statin type and dose may reveal varying risk levels for> new-onset DM in this population.> > > > > > > > > > ********************************************************************************> "Building Chiropractic Community through enhanced communication."> > To change your preferences or unsubscribe:> http://ww3.chirolists.com/mailman/listinfo/chirolist-ca> email: Chirolist-CA-request@...?subject=unsubscribe> List options tutorial:> http://www.chirolists.com/index.cfm?nid=6> Email filters tutorial:> http://www.chirolists.com/index.cfm?nid=7> *********************************************************************************

[Guest guest]

Vitamin C: The Real Story by Steve Hickey, PhD, & SAul, PhD, call arteriosclerosis 'moderate scurvy' and frank cardiovascular disease 'advanced scurvy'. Sure makes sense to me! SunnySunny Kierstyn, RN DC Fibromyalgia Care Center of Oregon 2677 Willakenzie Road, 7CEugene, Oregon, 97401541- 654-0850; Fx; 541- 654-0834www.drsunnykierstyn.com From: dcdocbrian@...Date: Mon, 30 Jan 2012 09:56:56 -0800Subject: RE: FW: [Chirolist-CA] Statins and diabetes

How about another article pointing out the "benefits" of statins? From the blog of Dr. Briffa (a British MD):Cholesterol-lowering-

Probably the biggest wank in the history of medicine.

A

soon-to-be published article in the journal Atherosclerosis adds to the vast sum of

research contradicting the cholesterol theory of cardiovascular disease.

In this study, researchers tracked 82,380

participants with no known history of cardiovascular disease for an average of

eight years (during the period 1994–2004) as part of the Health Survey for

England. Mean age of the subjects was 55.4 and the male:female ratio was 45:55.

Given

that we’ve been told ad naseum cholesterol causes coronary heart

disease (CHD), you’d expect blood cholesterol to assert itself as a robust risk

factor for heart disease in such a large study. With 82,380 participants

followed for almost a decade, and with 806 and 1346 subsequent deaths from

stroke and CHD deaths, respectively, cholesterol had every opportunity to leave

its allegedly deadly mark.

But it didn’t.

Total cholesterol levels didn’t make a whit of

difference to coronary heart disease risk, and were in fact associated with a

lower risk of stroke[1].

Oops. Bet this study won’t be getting the

extravagant media coverage given to all those shonky Big Pharma-sponsored

statin studies that are prematurely ended whilst the “miracle” drug is still

showing a piddling but “statistically significant” advantage…

So what factors were associated with increased

stroke and heart attack risk?

Only age, smoking, systolic BP, diabetes and

physical activity were predictive of stroke, while age, male gender (get those

iron levels checked fellas…), smoking, systolic blood pressure, HDL

cholesterol, diabetes, BMI, physical activity, CRP, and fibrinogen were

predictive of coronary heart disease.

Bottom line: Don’t smoke, do some regular

exercise, avoid high blood sugar levels, keep a healthy weight, and keep your

serum ferritin between 30-75 (depending on your activity levels). And give

cholesterol-phobia a good swift kick in its fraudulent backside.

References

1. Hamer

M, et al. Comparison of risk factors for fatal stroke and ischemic heart

disease: A prospective follow up of the health survey for England. Atherosclerosis (2011),

doi:10.1016/j.atherosclerosis.2011.08.016 Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724oregonchiro@...; From: caughlindrc@...Date: Mon, 30 Jan 2012 16:44:25 +0000Subject: FW: [Chirolist-CA] Statins and diabetes

FYI from another list serve.Dr. A Caughlin DC CAC155 NW 1st Ave Day, Or. 97845 office 541-575-1063 fax 541-575-5554> > ONLINE FIRST> Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the> Women's Health Initiative> > Annie L. Culver, BPharm; Ira S. Ockene, MD; Raji Balasubramanian, ScD;> Barbara C. Olendzki, RD, MPH; Deidre M. Sepavich, MBA;Wactawski-Wende,> PhD; JoAnn E. Manson, MD, DrPH; Yongxia Qiao, MD; Simin Liu, MD, ScD; Philip> A. Merriam, MSPH; Rahilly-Tierny, MD, MPH; Fridtjof , PhD;> S. Berger, MD, MS; Judith K. Ockene, PhD, MEd, MA; J. Curb,> MD;Yunsheng Ma, MD, PhD > > Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625> > Background This study investigates whether the incidence of new-onset> diabetes mellitus (DM) is associated with statin use among postmenopausal> women participating in the Women's Health Initiative (WHI).> > Methods The WHI recruited 161 808 postmenopausal women aged 50 to 79 years> at 40 clinical centers across the United States from 1993 to 1998 with> ongoing follow-up. The current analysis includes data through 2005. Statin> use was captured at enrollment and year 3. Incident DM status was determined> annually from enrollment. proportional hazards models were used to> estimate the risk of DM by statin use, with adjustments for propensity score> and other potential confounding factors. Subgroup analyses by> race/ethnicity, obesity status, and age group were conducted to uncover> effect modification.> > Results This investigation included 153 840 women without DM and no missing> data at baseline. At baseline, 7.04% reported taking statin medication.> There were 10 242 incident cases of self-reported DM over 1 004 466> person-years of follow-up. Statin use at baseline was associated with an> increased risk of DM (hazard ratio

---

, 1.71; 95% CI, 1.61-1.83). This> association remained after adjusting for other potential confounders> (multivariate-adjusted HR, 1.48; 95% CI, 1.38-1.59) and was observed for all> types of statin medications. Subset analyses evaluating the association of> self-reported DM with longitudinal measures of statin use in 125 575 women> confirmed these findings.> > Conclusions Statin medication use in postmenopausal women is associated> with an increased risk for DM. This may be a medication class effect.> Further study by statin type and dose may reveal varying risk levels for> new-onset DM in this population.> > > > > > > > > > ********************************************************************************> "Building Chiropractic Community through enhanced communication."> > To change your preferences or unsubscribe:> http://ww3.chirolists.com/mailman/listinfo/chirolist-ca> email: Chirolist-CA-request@...?subject=unsubscribe> List options tutorial:> http://www.chirolists.com/index.cfm?nid=6> Email filters tutorial:> http://www.chirolists.com/index.cfm?nid=7> *********************************************************************************

[Guest guest]

Good stuff …it is also my understand that some investigators believe the statins are also responsible for generating an entire generation of congestive heart failure cases due to their depleting Co-Q enzyme 10 which is vital for heart muscle strength……not sure that is accurate as I’m going by memory….Vern Saboe From: [mailto: ] On Behalf Of BRIAN SEITZSent: Monday, January 30, 2012 9:57 AM Subject: RE: FW: [Chirolist-CA] Statins and diabetes How about another article pointing out the " benefits " of statins? From the blog of Dr. Briffa (a British MD): Cholesterol-lowering- Probably the biggest wank in the history of medicine. A soon-to-be published article in the journal Atherosclerosis adds to the vast sum of research contradicting the cholesterol theory of cardiovascular disease.In this study, researchers tracked 82,380 participants with no known history of cardiovascular disease for an average of eight years (during the period 1994–2004) as part of the Health Survey for England. Mean age of the subjects was 55.4 and the male:female ratio was 45:55.Given that we’ve been told ad naseum cholesterol causes coronary heart disease (CHD), you’d expect blood cholesterol to assert itself as a robust risk factor for heart disease in such a large study. With 82,380 participants followed for almost a decade, and with 806 and 1346 subsequent deaths from stroke and CHD deaths, respectively, cholesterol had every opportunity to leave its allegedly deadly mark.But it didn’t.Total cholesterol levels didn’t make a whit of difference to coronary heart disease risk, and were in fact associated with a lower risk of stroke[1].Oops. Bet this study won’t be getting the extravagant media coverage given to all those shonky Big Pharma-sponsored statin studies that are prematurely ended whilst the “miracle” drug is still showing a piddling but “statistically significant” advantage…So what factors were associated with increased stroke and heart attack risk?Only age, smoking, systolic BP, diabetes and physical activity were predictive of stroke, while age, male gender (get those iron levels checked fellas…), smoking, systolic blood pressure, HDL cholesterol, diabetes, BMI, physical activity, CRP, and fibrinogen were predictive of coronary heart disease.Bottom line: Don’t smoke, do some regular exercise, avoid high blood sugar levels, keep a healthy weight, and keep your serum ferritin between 30-75 (depending on your activity levels). And give cholesterol-phobia a good swift kick in its fraudulent backside.References1. Hamer M, et al. Comparison of risk factors for fatal stroke and ischemic heart disease: A prospective follow up of the health survey for England. Atherosclerosis (2011), doi:10.1016/j.atherosclerosis.2011.08.016 Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724oregonchiro@...; From: caughlindrc@...Date: Mon, 30 Jan 2012 16:44:25 +0000Subject: FW: [Chirolist-CA] Statins and diabetes FYI from another list serve.Dr. A Caughlin DC CAC155 NW 1st Ave Day, Or. 97845 office 541-575-1063 fax 541-575-5554> > ONLINE FIRST> Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the> Women's Health Initiative> > Annie L. Culver, BPharm; Ira S. Ockene, MD; Raji Balasubramanian, ScD;> Barbara C. Olendzki, RD, MPH; Deidre M. Sepavich, MBA;Wactawski-Wende,> PhD; JoAnn E. Manson, MD, DrPH; Yongxia Qiao, MD; Simin Liu, MD, ScD; Philip> A. Merriam, MSPH; Rahilly-Tierny, MD, MPH; Fridtjof , PhD;> S. Berger, MD, MS; Judith K. Ockene, PhD, MEd, MA; J. Curb,> MD;Yunsheng Ma, MD, PhD > > Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625> > Background This study investigates whether the incidence of new-onset> diabetes mellitus (DM) is associated with statin use among postmenopausal> women participating in the Women's Health Initiative (WHI).> > Methods The WHI recruited 161 808 postmenopausal women aged 50 to 79 years> at 40 clinical centers across the United States from 1993 to 1998 with> ongoing follow-up. The current analysis includes data through 2005. Statin> use was captured at enrollment and year 3. Incident DM status was determined> annually from enrollment. proportional hazards models were used to> estimate the risk of DM by statin use, with adjustments for propensity score> and other potential confounding factors. Subgroup analyses by> race/ethnicity, obesity status, and age group were conducted to uncover> effect modification.> > Results This investigation included 153 840 women without DM and no missing> data at baseline. At baseline, 7.04% reported taking statin medication.> There were 10 242 incident cases of self-reported DM over 1 004 466> person-years of follow-up. Statin use at baseline was associated with an> increased risk of DM (hazard ratio

---

, 1.71; 95% CI, 1.61-1.83). This> association remained after adjusting for other potential confounders> (multivariate-adjusted HR, 1.48; 95% CI, 1.38-1.59) and was observed for all> types of statin medications. Subset analyses evaluating the association of> self-reported DM with longitudinal measures of statin use in 125 575 women> confirmed these findings.> > Conclusions Statin medication use in postmenopausal women is associated> with an increased risk for DM. This may be a medication class effect.> Further study by statin type and dose may reveal varying risk levels for> new-onset DM in this population.> > > > > > > > > > ********************************************************************************> " Building Chiropractic Community through enhanced communication. " > > To change your preferences or unsubscribe:> http://ww3.chirolists.com/mailman/listinfo/chirolist-ca> email: Chirolist-CA-request@...?subject=unsubscribe> List options tutorial:> http://www.chirolists.com/index.cfm?nid=6> Email filters tutorial:> http://www.chirolists.com/index.cfm?nid=7> *********************************************************************************

[Guest guest]

It is my understanding that the statins were intended to be the 'Next GREAT' replacement for vitamin D .... when that didn't happen, they HAD to find something to do with all of those pills so juggled the cholesterol figures, creating a 'new' demand. Problem is, they still didn't work. skSunny Kierstyn, RN DC Fibromyalgia Care Center of Oregon 2677 Willakenzie Road, 7CEugene, Oregon, 97401541- 654-0850; Fx; 541- 654-0834www.drsunnykierstyn.com dcdocbrian@...; From: vsaboe@...Date: Mon, 30 Jan 2012 10:50:12 -0800Subject: RE: FW: [Chirolist-CA] Statins and diabetes

Good stuff …it is also my understand that some investigators believe the statins are also responsible for generating an entire generation of congestive heart failure cases due to their depleting Co-Q enzyme 10 which is vital for heart muscle strength……not sure that is accurate as I’m going by memory….Vern Saboe From: [mailto: ] On Behalf Of BRIAN SEITZSent: Monday, January 30, 2012 9:57 AM Subject: RE: FW: [Chirolist-CA] Statins and diabetes How about another article pointing out the "benefits" of statins? From the blog of Dr. Briffa (a British MD): Cholesterol-lowering- Probably the biggest wank in the history of medicine. A soon-to-be published article in the journal Atherosclerosis adds to the vast sum of research contradicting the cholesterol theory of cardiovascular disease.In this study, researchers tracked 82,380 participants with no known history of cardiovascular disease for an average of eight years (during the period 1994–2004) as part of the Health Survey for England. Mean age of the subjects was 55.4 and the male:female ratio was 45:55.Given that we’ve been told ad naseum cholesterol causes coronary heart disease (CHD), you’d expect blood cholesterol to assert itself as a robust risk factor for heart disease in such a large study. With 82,380 participants followed for almost a decade, and with 806 and 1346 subsequent deaths from stroke and CHD deaths, respectively, cholesterol had every opportunity to leave its allegedly deadly mark.But it didn’t.Total cholesterol levels didn’t make a whit of difference to coronary heart disease risk, and were in fact associated with a lower risk of stroke[1].Oops. Bet this study won’t be getting the extravagant media coverage given to all those shonky Big Pharma-sponsored statin studies that are prematurely ended whilst the “miracle” drug is still showing a piddling but “statistically significant” advantage…So what factors were associated with increased stroke and heart attack risk?Only age, smoking, systolic BP, diabetes and physical activity were predictive of stroke, while age, male gender (get those iron levels checked fellas…), smoking, systolic blood pressure, HDL cholesterol, diabetes, BMI, physical activity, CRP, and fibrinogen were predictive of coronary heart disease.Bottom line: Don’t smoke, do some regular exercise, avoid high blood sugar levels, keep a healthy weight, and keep your serum ferritin between 30-75 (depending on your activity levels). And give cholesterol-phobia a good swift kick in its fraudulent backside.References1. Hamer M, et al. Comparison of risk factors for fatal stroke and ischemic heart disease: A prospective follow up of the health survey for England. Atherosclerosis (2011), doi:10.1016/j.atherosclerosis.2011.08.016 Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724oregonchiro@...; From: caughlindrc@...Date: Mon, 30 Jan 2012 16:44:25 +0000Subject: FW: [Chirolist-CA] Statins and diabetes FYI from another list serve.Dr. A Caughlin DC CAC155 NW 1st Ave Day, Or. 97845 office 541-575-1063 fax 541-575-5554> > ONLINE FIRST> Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the> Women's Health Initiative> > Annie L. Culver, BPharm; Ira S. Ockene, MD; Raji Balasubramanian, ScD;> Barbara C. Olendzki, RD, MPH; Deidre M. Sepavich, MBA;Wactawski-Wende,> PhD; JoAnn E. Manson, MD, DrPH; Yongxia Qiao, MD; Simin Liu, MD, ScD; Philip> A. Merriam, MSPH; Rahilly-Tierny, MD, MPH; Fridtjof , PhD;> S. Berger, MD, MS; Judith K. Ockene, PhD, MEd, MA; J. Curb,> MD;Yunsheng Ma, MD, PhD > > Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625> > Background This study investigates whether the incidence of new-onset> diabetes mellitus (DM) is associated with statin use among postmenopausal> women participating in the Women's Health Initiative (WHI).> > Methods The WHI recruited 161 808 postmenopausal women aged 50 to 79 years> at 40 clinical centers across the United States from 1993 to 1998 with> ongoing follow-up. The current analysis includes data through 2005. Statin> use was captured at enrollment and year 3. Incident DM status was determined> annually from enrollment. proportional hazards models were used to> estimate the risk of DM by statin use, with adjustments for propensity score> and other potential confounding factors. Subgroup analyses by> race/ethnicity, obesity status, and age group were conducted to uncover> effect modification.> > Results This investigation included 153 840 women without DM and no missing> data at baseline. At baseline, 7.04% reported taking statin medication.> There were 10 242 incident cases of self-reported DM over 1 004 466> person-years of follow-up. Statin use at baseline was associated with an> increased risk of DM (hazard ratio

---

, 1.71; 95% CI, 1.61-1.83). This> association remained after adjusting for other potential confounders> (multivariate-adjusted HR, 1.48; 95% CI, 1.38-1.59) and was observed for all> types of statin medications. Subset analyses evaluating the association of> self-reported DM with longitudinal measures of statin use in 125 575 women> confirmed these findings.> > Conclusions Statin medication use in postmenopausal women is associated> with an increased risk for DM. This may be a medication class effect.> Further study by statin type and dose may reveal varying risk levels for> new-onset DM in this population.> > > > > > > > > > ********************************************************************************> "Building Chiropractic Community through enhanced communication."> > To change your preferences or unsubscribe:> http://ww3.chirolists.com/mailman/listinfo/chirolist-ca> email: Chirolist-CA-request@...?subject=unsubscribe> List options tutorial:> http://www.chirolists.com/index.cfm?nid=6> Email filters tutorial:> http://www.chirolists.com/index.cfm?nid=7> *********************************************************************************

[Guest guest]

Yea Sunny I can tell they don’t work by all the TV commercial information…..lol…. Vern From: Sunny Kierstyn [mailto:skrndc1@...] Sent: Monday, January 30, 2012 11:07 AMVern Saboe; Seitz; Subject: RE: FW: [Chirolist-CA] Statins and diabetes It is my understanding that the statins were intended to be the 'Next GREAT' replacement for vitamin D .... when that didn't happen, they HAD to find something to do with all of those pills so juggled the cholesterol figures, creating a 'new' demand. Problem is, they still didn't work. skSunny Kierstyn, RN DC Fibromyalgia Care Center of Oregon 2677 Willakenzie Road, 7CEugene, Oregon, 97401541- 654-0850; Fx; 541- 654-0834www.drsunnykierstyn.com dcdocbrian@...; From: vsaboe@...Date: Mon, 30 Jan 2012 10:50:12 -0800Subject: RE: FW: [Chirolist-CA] Statins and diabetes Good stuff …it is also my understand that some investigators believe the statins are also responsible for generating an entire generation of congestive heart failure cases due to their depleting Co-Q enzyme 10 which is vital for heart muscle strength……not sure that is accurate as I’m going by memory….Vern Saboe From: [mailto: ] On Behalf Of BRIAN SEITZSent: Monday, January 30, 2012 9:57 AM Subject: RE: FW: [Chirolist-CA] Statins and diabetes How about another article pointing out the " benefits " of statins? From the blog of Dr. Briffa (a British MD): Cholesterol-lowering- Probably the biggest wank in the history of medicine. A soon-to-be published article in the journal Atherosclerosis adds to the vast sum of research contradicting the cholesterol theory of cardiovascular disease.In this study, researchers tracked 82,380 participants with no known history of cardiovascular disease for an average of eight years (during the period 1994–2004) as part of the Health Survey for England. Mean age of the subjects was 55.4 and the male:female ratio was 45:55.Given that we’ve been told ad naseum cholesterol causes coronary heart disease (CHD), you’d expect blood cholesterol to assert itself as a robust risk factor for heart disease in such a large study. With 82,380 participants followed for almost a decade, and with 806 and 1346 subsequent deaths from stroke and CHD deaths, respectively, cholesterol had every opportunity to leave its allegedly deadly mark.But it didn’t.Total cholesterol levels didn’t make a whit of difference to coronary heart disease risk, and were in fact associated with a lower risk of stroke[1].Oops. Bet this study won’t be getting the extravagant media coverage given to all those shonky Big Pharma-sponsored statin studies that are prematurely ended whilst the “miracle” drug is still showing a piddling but “statistically significant” advantage…So what factors were associated with increased stroke and heart attack risk?Only age, smoking, systolic BP, diabetes and physical activity were predictive of stroke, while age, male gender (get those iron levels checked fellas…), smoking, systolic blood pressure, HDL cholesterol, diabetes, BMI, physical activity, CRP, and fibrinogen were predictive of coronary heart disease.Bottom line: Don’t smoke, do some regular exercise, avoid high blood sugar levels, keep a healthy weight, and keep your serum ferritin between 30-75 (depending on your activity levels). And give cholesterol-phobia a good swift kick in its fraudulent backside.References1. Hamer M, et al. Comparison of risk factors for fatal stroke and ischemic heart disease: A prospective follow up of the health survey for England. Atherosclerosis (2011), doi:10.1016/j.atherosclerosis.2011.08.016 Seitz, DC Tuality Physicians 730-D SE Oak St Hillsboro, OR 97123 (503)640-3724oregonchiro@...; From: caughlindrc@...Date: Mon, 30 Jan 2012 16:44:25 +0000Subject: FW: [Chirolist-CA] Statins and diabetes FYI from another list serve.Dr. A Caughlin DC CAC155 NW 1st Ave Day, Or. 97845 office 541-575-1063 fax 541-575-5554> > ONLINE FIRST> Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the> Women's Health Initiative> > Annie L. Culver, BPharm; Ira S. Ockene, MD; Raji Balasubramanian, ScD;> Barbara C. Olendzki, RD, MPH; Deidre M. Sepavich, MBA;Wactawski-Wende,> PhD; JoAnn E. Manson, MD, DrPH; Yongxia Qiao, MD; Simin Liu, MD, ScD; Philip> A. Merriam, MSPH; Rahilly-Tierny, MD, MPH; Fridtjof , PhD;> S. Berger, MD, MS; Judith K. Ockene, PhD, MEd, MA; J. Curb,> MD;Yunsheng Ma, MD, PhD > > Arch Intern Med. 2012;172(2):144-152. doi:10.1001/archinternmed.2011.625> > Background This study investigates whether the incidence of new-onset> diabetes mellitus (DM) is associated with statin use among postmenopausal> women participating in the Women's Health Initiative (WHI).> > Methods The WHI recruited 161 808 postmenopausal women aged 50 to 79 years> at 40 clinical centers across the United States from 1993 to 1998 with> ongoing follow-up. The current analysis includes data through 2005. Statin> use was captured at enrollment and year 3. Incident DM status was determined> annually from enrollment. proportional hazards models were used to> estimate the risk of DM by statin use, with adjustments for propensity score> and other potential confounding factors. Subgroup analyses by> race/ethnicity, obesity status, and age group were conducted to uncover> effect modification.> > Results This investigation included 153 840 women without DM and no missing> data at baseline. At baseline, 7.04% reported taking statin medication.> There were 10 242 incident cases of self-reported DM over 1 004 466> person-years of follow-up. Statin use at baseline was associated with an> increased risk of DM (hazard ratio

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, 1.71; 95% CI, 1.61-1.83). This> association remained after adjusting for other potential confounders> (multivariate-adjusted HR, 1.48; 95% CI, 1.38-1.59) and was observed for all> types of statin medications. Subset analyses evaluating the association of> self-reported DM with longitudinal measures of statin use in 125 575 women> confirmed these findings.> > Conclusions Statin medication use in postmenopausal women is associated> with an increased risk for DM. This may be a medication class effect.> Further study by statin type and dose may reveal varying risk levels for> new-onset DM in this population.> > > > > > > > > > ********************************************************************************> " Building Chiropractic Community through enhanced communication. " > > To change your preferences or unsubscribe:> http://ww3.chirolists.com/mailman/listinfo/chirolist-ca> email: Chirolist-CA-request@...?subject=unsubscribe> List options tutorial:> http://www.chirolists.com/index.cfm?nid=6> Email filters tutorial:> http://www.chirolists.com/index.cfm?nid=7> *********************************************************************************