pregnancies and deliveries in CMT disease

April 13, 2005

(I have pulled the abstract of the article and I hope we will have

the entire article very soon. I wonder about a few things: 1) this

was done in Norway, starting in the late 1960's. Could medical care

have been different then, considering the start date and being in

another country? 2) I wonder what physical shape the mothers were in

before delivery, if they exercised, what their abdominal muscles were

like, or took vitamins or what the pre-natal care was like? 3) Could

the use of forceps been used more then? I'm just thinking outloud

here. lol. I hope when we have the entire paper more light will dawn

on this subject. From my own (and obviously limited) experience, when

I was about 17, my neurologist had a talk with me about having

children, and he did mention while I certainly " could " have children,

I " might " experience problems in delivery. ~ Gretchen

---------------

Pregnancies and deliveries in patients with Charcot-Marie-Tooth

disease.

Hoff JM, Gilhus NE, Daltveit AK.

Section for Neurology, Department of Clinical Medicine, University of

Bergen, Bergen, Norway.

OBJECTIVE: To investigate the effect of maternal Charcot-Marie-Tooth

disease (CMT) on pregnancy and delivery.

METHODS: Data from the Medical Birth Registry of Norway 1967 to 2002

were surveyed. This registry has compulsory notification of all

births. One hundred eight births by mothers with CMT were identified.

The reference group consisted of all 2.1 million births by mothers

without CMT.

RESULTS: Women with CMT had a higher occurrence of presentation

anomalies (9.3 vs 4.5%; p = 0.04) and bleeding post partum (12.0 vs

5.8%; p = 0.02). The rate of operative delivery was twice that of the

reference group (29.6 vs 15.3%; p = 0.002), and forceps was used

three times as often in the CMT group (9.3 vs 2.7; p < 0.001). The

majority of CMT cesarean sections were emergency sections.

CONCLUSION: Charcot-Marie-Tooth disease increases the risk for

complications during delivery, which is linked to a higher occurrence

of emergency interventions during birth.

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