What Are Systemic Enzymes and What Do They Do? + References

[Guest guest]

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MicrosoftInternetExplorer4

What Are Systemic Enzymesand What Do They Do?

By: Wong N.D.,Ph.D. Member World Sports Medicine Hall of Fame

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MicrosoftInternetExplorer4

http://www.systemicenzymetherapy.com/TherapeuticApplications/SystemicEnzymes.htm

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MicrosoftInternetExplorer4 The word **systemic** means body wide. Systemic

enzymes arethose that operate not just for digestion but throughout your body in

everysystem and organ. But let’s take first things first, what is an enzyme?

 

An enzyme is a biocatalyst - something that makes somethingelse work or work

faster. Chemical reactions are generally slow things, enzymesspeed them up.

Without enzymes the chemical reactions that make up our lifewould be too slow

for life as we know it. (As slow as sap running down a treein winter). For life

to manifest as we know it, enzymes are essential to speedup the reactions. We

have roughly some 3000 enzymes in our bodies and thatresults in over25,000 to

30,000 enzymic reactions. Most of these enzymes arederived or created from what

we think of as the protein digesting enzymes. Butwhile digestion is an important

part of what enzymes do, it's almost theabsolute last function. First and

foremost these body wide proteolytic (proteineating) enzymes have the following

actions:

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MicrosoftInternetExplorer4

 

Natural Anti-Inflammatory.

 

They are the first line of defense against inflammation.(1,2,3). Inflammation is

a reaction by the immune system to an irritation.Let’s say you have an injured

right knee. The immune system sensing theirritation the knee is undergoing

creates a protein chain called a CirculatingImmune Complex (CIC for short),

tagged specifically for that right knee. (TheNobel Prize in biology was won in

1999 by a scientist who discovered thistagging mechanism). This CIC floats down

to the right knee and causes pain,redness and swelling are the classic earmarks

for inflammation. This at firstis a beneficial reaction; it warns us that a part

of ourselves is hurt andneeds attention. But, inflammation is self-perpetuating,

itself creating anirritation that the body makes CIC’s to in response!

 

Aspirin, Ibuprofen, Celebrex, Vioxx and the rest of the NonSteroidal Anti

Inflammatory Drugs all work by keeping the body from making allCIC's. This

ignores the fact that some CIC’s are vital to life, like those thatmaintain

the lining of the intestine and those that keep the kidneysfunctioning! Not to

mention the fact that the NSAID’s, along withacetaminophen, are highly toxic

to the liver. Every year 20,000 Americans diefrom these over the counter drugs

and another 100,000 will wind up in thehospital with liver damage, kidney damage

or bleeding intestines from the sideeffects of these drugs. (4,5).

 

Systemic enzymes on the other hand are perfectly safe andfree of dangerous side

effects. They have no LD-50, or toxic dose. (6). Best ofall systemic enzymes can

tell the difference between the good CIC’s and the badones because hydrolytic

enzymes are lock and key mechanisms and their " teeth " will only fit over the bad

CIC’s. So instead of preventingthe creation of all CIC’s, systemic enzymes

just “eat†the bad ones and in sodoing lower inflammation everywhere. With

that, pain is lowered also.

 

 

Anti Fibrosis. 

 

Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissueand most

doctors learn in anatomy that it is fibrosis that eventually kills usall. Let me

explain. As we age, which starts at 27, we have a diminishing ofthe bodies’

output of enzymes. This is because we make a finite amount ofenzymes in a

lifetime and we use up a good deal of them by the time we are 27.At that point

the body knows that if it keeps up that rate of consumption we’llrun out of

enzymes and be dead by the time we reach our 40’s. (Cystic Fibrosispatients

who have virtually no enzyme production to speak of, even as childrenusually

don’t make it past their 20’s before they die of the restriction

andshrinkage in the lungs from the formation of fibrosis or scar tissue).

 

So our body in it's wisdom begins to dole out our enzymeswith an eyedropper

instead of with a tablespoon; as a result the repairmechanism of the body goes

out of balance and has nothing to reduce the overabundance of fibrin it deposits

in nearly every thing from simple cuts, to theinside of our internal organs and

blood vessels. This is when most women beginto develop things like fibrocystic

breast disease, uterine fibroids,endometriosis, and we all grow arterial

sclerotic (meaning scar tissue) plaque,and have fibrin beginning to spider web

its way inside of our internal organsreducing their size and function over time.

This is why as we age our woundsheal with thicker, less pliable, weaker and very

visible scars.

 

If we replace the lost enzymes we can control and reduce theamount of scar

tissue and fibrosis our bodies have. As physicians in the US are nowdiscovering,

even old scar tissue can be “eaten away†from surgical wounds,pulmonary

fibrosis, kidney fibrosis and even keloids years after theirformation. Medical

doctors in Europe and Asiahave known this and have used orally administered

enzymes for these situationsfor over 40 years!

 

 

Blood Cleansing.

 

The blood is not only the river of life, it is also theriver through which the

cells and organs dispose of their garbage and deadmaterial. Enzymes improve

circulation by eating the excess fibrin that causesblood to sometimes get as

thick as catsup or yogurt, creating the perfectenvironment for the formation of

clots. All of this material is supposed to becleared by the liver on its " first

pass " , or the first time it goesthrough but given the sluggish and near toxic or

toxic states of everyone'sliver these days that seldom happens. So the sludge

remains in the bloodwaiting for the liver to have enough free working space and

enough enzymes toclean the trash out of the blood. This can take days, and in

some cases, weeks!(8).

 

 

When systemic enzymes are taken, they stand ready in theblood and take the

strain off of the liver by:

 

Cleaning excess fibrin from the blood and reducing the stickiness of blood

cells. These two actions minimize the leading causes of stroke and heart

attack causing blood clots. (8).

 

Breaking dead material down small enough that it can immediately pass into

the bowel. (8).

 

Cleanse the FC receptors on the white blood cells improving their function

and availability to fight off infection. (9).

 

 

And here we come to the only warning we have to giveconcerning the use of

systemic enzymes - don't use the product if you are ahemophiliac or are on

prescription blood thinners like Coumadin, Heparin andPlavix, without direct

medical supervision. The enzymes cause the drugs to workbetter so there is the

possibility of thinning the blood too much.

 

 

Immune System Modulating.

 

Enzymes are adaptogenic seeking to restore a steady state tothe body. (9). When

the immune system is running low we become susceptible toinfectious disease,

when it’s cranked up too high then the system createsantibodies that attack

it's own tissues as are seen in the auto immune diseasesof MS, Rheumatoid

Arthritis, and Lupus. Here the enzymes will tone down immunefunction and eat

away at the antibodies the immune system is making to attackits bodies own

tissue.

 

 

Virus Fighting.

 

Viruses harm us by replicating in our bodies. To do this avirus must bond itself

to the DNA in our cells through the medium of itsexterior protein cell wall.

Anything that disrupts that cell wall inhibits theability of viral replication

by rendering individual viruses inert. (10,11).Systemic enzymes can tell the

difference between the proteins that are supposedto be in your body and those

that are foreign or not supposed to be there,(again the enzyme lock and key

mechanism).

 

One note: many inthe States have learned in school that enzymes are too big a

protein to beabsorbed through the gut. The pioneering research done in the US by

Dr. Max Wolf (MD & PhD x7) at Columbia University in the 40’s through the

70’shas not made it to the awareness of most doctors. There are currently over

200peer reviewed research articles dealing with the absorption, utilization

andtherapeutic action of orally administered systemic enzymes. A search

throughPub Med using the key words:  serrapeptase, papain, bromelain,

trypsin,chymo trypsin, nattokinase and systemic enzyme will yield some of the

extensivework. Systemic enzymes now have a 4decade plus history of widespread

medical use in central Europe and Japan.

 

 

References:

 

1) Carroll A., R.: Clinical examination of an enzymaticanti-inflammatory agent

in emergency surgery. Arztl. Praxis 24 (1972), 2307.

 

2) Mazzone A, et al.: Evaluation of Serratia peptidase inacute or chronic

inflammation of otorhinolaryngology pathology: amulticentre, double blind,

randomized trial versus placebo. J Int Med Res. 1990;18(5):379-88.

 

3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatmentof breast engorgement

with Serrapeptase: a randomized double blind controlledtrial. SingaporeMed J.

1989:30(l):48-54.

 

4) Celebrex article Wall Street Journal 19 April 1999.

 

5) No author listed: Regular Use of Pain Relievers Can HaveDangerous Results.

Kaleidoscope Interactive News, American Medical Associationmedia briefing. July

24, 1997.

 

6) Enzymes ñ A Drug of the Future, Prof. Heinrich Wrba MDand Otto Pecher MD.

Published 1993 Eco Med.

 

7) Kakinumu A. et al.: Regression of fibrinolysis in scaldedrats by

administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.

 

8) Ernst E., Matrai A.: Oral Therapy with proteolyticenzymes for modifying blood

rheology. Klin Wschr. 65 (1987), 994.

 

9) Kunze R., Ransberger K., et at: Humoral immunomodulatorycapasity of proteases

in immune complex decomposition and formation. FirstInternational symposium on

combination therapies, Washington, DC,1991.

 

10) Jager H.: Hydrolytic Enzymes in the therapy of HIVdisease. Zeitschr.

Allgemeinmed., 19 (1990), 160.

 

11) Bartsch W.: The treatment of herpes zoster usingproteolytic enzymes. Der

Informierte Arzt. 2 (1974), 424-429.

 

[Guest guest]

This is a bit of a mess - I do have this also on a Word document - if you can

wait until Monday I can email this article to anybody whom would like it.

blessings

Shan

>

> Normal 0 false false false

MicrosoftInternetExplorer4

>

> What Are Systemic Enzymesand What Do They Do?

> By: Wong N.D.,Ph.D. Member World Sports Medicine Hall of Fame

> Normal 0 false false false

MicrosoftInternetExplorer4

http://www.systemicenzymetherapy.com/TherapeuticApplications/SystemicEnzymes.htm

>

>

>

> Normal 0 false false false

MicrosoftInternetExplorer4 The word **systemic** means body wide. Systemic

enzymes arethose that operate not just for digestion but throughout your body in

everysystem and organ. But let’s take first things first, what is an enzyme?

>  

> An enzyme is a biocatalyst - something that makes somethingelse work or work

faster. Chemical reactions are generally slow things, enzymesspeed them up.

Without enzymes the chemical reactions that make up our lifewould be too slow

for life as we know it. (As slow as sap running down a treein winter). For life

to manifest as we know it, enzymes are essential to speedup the reactions. We

have roughly some 3000 enzymes in our bodies and thatresults in over25,000 to

30,000 enzymic reactions. Most of these enzymes arederived or created from what

we think of as the protein digesting enzymes. Butwhile digestion is an important

part of what enzymes do, it's almost theabsolute last function. First and

foremost these body wide proteolytic (proteineating) enzymes have the following

actions:

>

>

> Normal 0 false false false

MicrosoftInternetExplorer4

>  

> Natural Anti-Inflammatory.

>  

> They are the first line of defense against inflammation.(1,2,3). Inflammation

is a reaction by the immune system to an irritation.Let’s say you have an

injured right knee. The immune system sensing theirritation the knee is

undergoing creates a protein chain called a CirculatingImmune Complex (CIC for

short), tagged specifically for that right knee. (TheNobel Prize in biology was

won in 1999 by a scientist who discovered thistagging mechanism). This CIC

floats down to the right knee and causes pain,redness and swelling are the

classic earmarks for inflammation. This at firstis a beneficial reaction; it

warns us that a part of ourselves is hurt andneeds attention. But, inflammation

is self-perpetuating, itself creating anirritation that the body makes CIC’s

to in response!

>  

> Aspirin, Ibuprofen, Celebrex, Vioxx and the rest of the NonSteroidal Anti

Inflammatory Drugs all work by keeping the body from making allCIC's. This

ignores the fact that some CIC’s are vital to life, like those thatmaintain

the lining of the intestine and those that keep the kidneysfunctioning! Not to

mention the fact that the NSAID’s, along withacetaminophen, are highly toxic

to the liver. Every year 20,000 Americans diefrom these over the counter drugs

and another 100,000 will wind up in thehospital with liver damage, kidney damage

or bleeding intestines from the sideeffects of these drugs. (4,5).

>  

> Systemic enzymes on the other hand are perfectly safe andfree of dangerous

side effects. They have no LD-50, or toxic dose. (6). Best ofall systemic

enzymes can tell the difference between the good CIC’s and the badones because

hydrolytic enzymes are lock and key mechanisms and their " teeth " will only fit

over the bad CIC’s. So instead of preventingthe creation of all CIC’s,

systemic enzymes just “eat†the bad ones and in sodoing lower inflammation

everywhere. With that, pain is lowered also.

>  

>  

> Anti Fibrosis. 

>  

> Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissueand most

doctors learn in anatomy that it is fibrosis that eventually kills usall. Let me

explain. As we age, which starts at 27, we have a diminishing ofthe bodies’

output of enzymes. This is because we make a finite amount ofenzymes in a

lifetime and we use up a good deal of them by the time we are 27.At that point

the body knows that if it keeps up that rate of consumption we’llrun out of

enzymes and be dead by the time we reach our 40’s. (Cystic Fibrosispatients

who have virtually no enzyme production to speak of, even as childrenusually

don’t make it past their 20’s before they die of the restriction

andshrinkage in the lungs from the formation of fibrosis or scar tissue).

>  

> So our body in it's wisdom begins to dole out our enzymeswith an eyedropper

instead of with a tablespoon; as a result the repairmechanism of the body goes

out of balance and has nothing to reduce the overabundance of fibrin it deposits

in nearly every thing from simple cuts, to theinside of our internal organs and

blood vessels. This is when most women beginto develop things like fibrocystic

breast disease, uterine fibroids,endometriosis, and we all grow arterial

sclerotic (meaning scar tissue) plaque,and have fibrin beginning to spider web

its way inside of our internal organsreducing their size and function over time.

This is why as we age our woundsheal with thicker, less pliable, weaker and very

visible scars.

>  

> If we replace the lost enzymes we can control and reduce theamount of scar

tissue and fibrosis our bodies have. As physicians in the US are nowdiscovering,

even old scar tissue can be “eaten away†from surgical wounds,pulmonary

fibrosis, kidney fibrosis and even keloids years after theirformation. Medical

doctors in Europe and Asiahave known this and have used orally administered

enzymes for these situationsfor over 40 years!

>  

>  

> Blood Cleansing.

>  

> The blood is not only the river of life, it is also theriver through which the

cells and organs dispose of their garbage and deadmaterial. Enzymes improve

circulation by eating the excess fibrin that causesblood to sometimes get as

thick as catsup or yogurt, creating the perfectenvironment for the formation of

clots. All of this material is supposed to becleared by the liver on its " first

pass " , or the first time it goesthrough but given the sluggish and near toxic or

toxic states of everyone'sliver these days that seldom happens. So the sludge

remains in the bloodwaiting for the liver to have enough free working space and

enough enzymes toclean the trash out of the blood. This can take days, and in

some cases, weeks!(8).

>  

>  

> When systemic enzymes are taken, they stand ready in theblood and take the

strain off of the liver by:

>  

> Cleaning excess fibrin from the blood and reducing the stickiness of blood

cells. These two actions minimize the leading causes of stroke and heart

attack causing blood clots. (8).

>  

> Breaking dead material down small enough that it can immediately pass into

the bowel. (8).

>  

> Cleanse the FC receptors on the white blood cells improving their function

and availability to fight off infection. (9).

>  

>  

> And here we come to the only warning we have to giveconcerning the use of

systemic enzymes - don't use the product if you are ahemophiliac or are on

prescription blood thinners like Coumadin, Heparin andPlavix, without direct

medical supervision. The enzymes cause the drugs to workbetter so there is the

possibility of thinning the blood too much.

>  

>  

> Immune System Modulating.

>  

> Enzymes are adaptogenic seeking to restore a steady state tothe body. (9).

When the immune system is running low we become susceptible toinfectious

disease, when it’s cranked up too high then the system createsantibodies that

attack it's own tissues as are seen in the auto immune diseasesof MS, Rheumatoid

Arthritis, and Lupus. Here the enzymes will tone down immunefunction and eat

away at the antibodies the immune system is making to attackits bodies own

tissue.

>  

>  

> Virus Fighting.

>  

> Viruses harm us by replicating in our bodies. To do this avirus must bond

itself to the DNA in our cells through the medium of itsexterior protein cell

wall. Anything that disrupts that cell wall inhibits theability of viral

replication by rendering individual viruses inert. (10,11).Systemic enzymes can

tell the difference between the proteins that are supposedto be in your body and

those that are foreign or not supposed to be there,(again the enzyme lock and

key mechanism).

>  

> One note: many inthe States have learned in school that enzymes are too big a

protein to beabsorbed through the gut. The pioneering research done in the US by

Dr. Max Wolf (MD & PhD x7) at Columbia University in the 40’s through the

70’shas not made it to the awareness of most doctors. There are currently over

200peer reviewed research articles dealing with the absorption, utilization

andtherapeutic action of orally administered systemic enzymes. A search

throughPub Med using the key words:  serrapeptase, papain, bromelain,

trypsin,chymo trypsin, nattokinase and systemic enzyme will yield some of the

extensivework. Systemic enzymes now have a 4decade plus history of widespread

medical use in central Europe and Japan.

>  

>  

> References:

>

>

>  

> 1) Carroll A., R.: Clinical examination of an enzymaticanti-inflammatory agent

in emergency surgery. Arztl. Praxis 24 (1972), 2307.

>  

> 2) Mazzone A, et al.: Evaluation of Serratia peptidase inacute or chronic

> inflammation of otorhinolaryngology pathology: amulticentre, double blind,

> randomized trial versus placebo. J Int Med Res. 1990;18(5):379-88.

>  

> 3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatmentof breast

engorgement with Serrapeptase: a randomized double blind controlledtrial.

SingaporeMed J. 1989:30(l):48-54.

>  

> 4) Celebrex article Wall Street Journal 19 April 1999.

>  

> 5) No author listed: Regular Use of Pain Relievers Can HaveDangerous Results.

Kaleidoscope Interactive News, American Medical Associationmedia briefing. July

24, 1997.

>  

> 6) Enzymes ñ A Drug of the Future, Prof. Heinrich Wrba MDand Otto Pecher MD.

Published 1993 Eco Med.

>  

> 7) Kakinumu A. et al.: Regression of fibrinolysis in scaldedrats by

administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.

>  

> 8) Ernst E., Matrai A.: Oral Therapy with proteolyticenzymes for modifying

blood rheology. Klin Wschr. 65 (1987), 994.

>  

> 9) Kunze R., Ransberger K., et at: Humoral immunomodulatorycapasity of

proteases in immune complex decomposition and formation. FirstInternational

symposium on combination therapies, Washington, DC,1991.

>  

> 10) Jager H.: Hydrolytic Enzymes in the therapy of HIVdisease. Zeitschr.

Allgemeinmed., 19 (1990), 160.

>  

> 11) Bartsch W.: The treatment of herpes zoster usingproteolytic enzymes. Der

Informierte Arzt. 2 (1974), 424-429.

>  

>

>

>

>