Co-Cure: Treatment of Chronic Fatigue Syndrome and Fibromyalgia with D-Ribose– An Open-label, Multicenter Study

[Guest guest]

forwarded...........................

Date: Wed, 4 Jul 2012 10:30:45 -0500From: kelly

& lt;kellylatta66@... & gt;Subject: RES: Treatment of Chronic Fatigue

Syndrome and Fibromyalgia with D-Ribose– An Open-label, Multicenter Study

The Open Pain Journal

Treatment of Chronic Fatigue Syndrome and Fibromyalgia with D-Ribose–An

Open-label, Multicenter Study Teitelbaum, Janelle Jandrain and McGrew

Pp 32-37

Objectives: Chronic Fatigue Syndrome and Fibromyalgia (CFS/FMS) aredebilitating

syndromes affecting ~2- 4% of the population. Althoughthey are heterogeneous

conditions associated with many triggers, theyappear to have the common

pathology of being associated with impairedenergy metabolism.

As D-ribose has been shown to increase cellular energy synthesis, andwas shown

to significantly improve clinical outcomes in CFS/FMS in anearlier study, we

hypothesized that giving D-ribose would improvefunction in CFS/FMS patients.

Design, Location, and Subjects: An open-label, unblinded study inwhich 53 US

clinics enrolled 257 patients who had been given adiagnosis of CFS/FMS by a

health practitioner.

Interventions: All subjects were given D-ribose (Corvalenâ„¢), anaturally

occurring pentose carbohydrate, 5-g TID for 3 weeks.

Outcome measures: All patients were assessed at baseline (1 weekbefore

treatment), and after 1,2, & 3 weeks using a Visual AnalogScale(1-7 points)

rating energy, sleep, cognitive function, pain andoverall well being.

Results: 203 patients completed the 3 week treatment trial. D-ribosetreatment

led to both statistically(p & lt;.0001) and clinically highlyimportant average

improvements in all categories:• 61.3 % increase in energy• 37% increase in

overall well being• 29.3% improvement in sleep

ISSN: 1876-3863 [DOI:

10.2174/1876386301205010032]http://benthamscience.com/open/openaccess.php?topain\

j/articles/V005/32TOPAINJ.htm

 --------------------------------------------- Send posts to

CO-CURE@... Unsubscribe at

http://www.co-cure.org/unsub.htm

---------------------------------------------Co-Cure's purpose is to provide

information from across the spectrum ofopinion concerning medical, research and

political aspects of ME/CFS and/orFMS. We take no position on the validity of

any specific scientific orpolitical opinion expressed in Co-Cure posts, and we

urge readers toresearch the various opinions available before assuming any

oneinterpretation is definitive. The Co-Cure website & lt;www.co-cure.org & gt; has

alink to our complete archive of posts as well as articles of centralimportance

to the issues of our community.

---------------------------------------------