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DOOs and POOs

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All,When thinking about " outcomes " , whether in research study design, or application of outcomes in clinical practice with individual patients, the notion of Disease Oriented Outcomes (DOOs) and Patient Oriented Outcomes (POOs) is worth considering.

DOOs tend to be measures  of some kind such as lab values, orthopedic tests, measures of subluxation, and the like.  As opposed to POOs that are relative to the patient's experience of outcomes.

A recent example form acupuncture research comes to mind (don't have the citation in front of me) where the result of the acu intervention in asthmatics was no change in the DOO (peak flow, O2 saturation) but marked improvement in the POO...the acu treated asthmatics actually felt better in terms of POOs.

This has an interesting discussion in a recent NEJM piece  here http://www.nejm.org/doi/full/10.1056/NEJMp1113631 

Perhaps the most important barrier to goal-oriented care is that medicine is deeply rooted in a disease-outcome–based paradigm. Rather than asking what patients want, the culture has valued managing each disease as well as possible according to guidelines and population goals. A. Simpson, DC | Vice President, Medical DirectorThe CHP Group | Smart Solutions. Healthy Results.

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