Type 2 Diabetes, Depression and Magnesium

[Guest guest]

Normal 0 false false false

MicrosoftInternetExplorer4 Type 2Diabetes, Depression and Magnesium

http://nutritionalmagnesium.org/research/diabetes/369-type-2-diabetes-depression\

-and-magnesium.html

?

?

Correlation of Magnesium Intake With MetabolicParameters, Depression and

Physical Activity in Elderly Type 2 DiabetesPatients: A Cross-Sectional Study

Jui-Hua Huang, Yi-Fa Lu, Fu-Chou Cheng, Ning-Yuean Leeand Leih-Ching Tsai

Nutrition Journal 2012, 11:41 doi:10.1186/1475-2891-11-41

Published: 13 June 2012

Abstract (provisional)

Background

Type 2 diabetes mellitus is a major global public health problem in theworldwide

and is increasing in aging populations. Magnesium intake may be oneof the most

important factors for diabetes prevention and management. Lowmagnesium intake

may exacerbate metabolic abnormalities. In this study, therelationships of

magnesium intake with metabolic parameters, depression andphysical activity in

elderly patients with type 2 diabetes were investigated.

?

Methods

?

This cross-sectional study involved 210 type 2 diabetespatients aged 65 years

and above. Participants were interviewed to obtaininformation on lifestyle and

24-hour dietary recall. Assessment of depressionwas based on DSM-IV criteria.

Clinical variables measured includedanthropometric measurements, blood pressure,

and biochemical determinations ofblood and urine samples. Linear regression was

applied to determine therelationships of magnesium intake with nutritional

variables and metabolicparameters.

?

Results

?

Among all patients, 88.6% had magnesium intake which wasless than the dietary

reference intake, and 37.1% had hypomagnesaemia.Metabolic syndromes and

depression were associated with lower magnesium intake(p & lt; 0.05). A positive

relationship was found between magnesium intake andHDL-cholesterol (p = 0.005).

Magnesium intake was inversely correlated withtriglyceride, waist circumference,

body fat percent and body mass index (p & lt;0.005). After controlling

confounding factor, HDL-cholesterol was significantlyhigher with increasing

quartile of magnesium intake (p for trend = 0005). Waistcircumference, body fat

percentage, and body mass index were significantlylower with increase quartile

of magnesium intake (p for trend & lt; 0.001). Theodds of depression, central

obesity, high body fat percentage, and high bodymass index were significantly

lower with increasing quartile of magnesiumintake (p for trend & lt; 0.05). In

addition, magnesium intake was related tohigh physical activity level and

demonstrated lower serum magnesium levels.Serum magnesium was not significantly

associated with metabolic parameters.

?

Conclusions

?

The majority of elderly type 2 diabetes who have lowmagnesium intake may

compound this deficiency with metabolic abnormalities anddepression. Future

studies should determine the effects of increased magnesiumintake or magnesium

supplementation on metabolic control and depression inelderly people with type 2

diabetes.