Aggressive Therapy in Rheumatoid Arthritis (RA)

May 24, 2002

The treatment of RA has recently been re-examined. It has been said that

traditional methods of treatment fails to prevent joint damage and

disability in many patients. Even when initially helpful, the first line

drugs used in treating RA provide effective control of inflammation for very

few patients. A new group of drugs must be turned to in order to provide

relief. These drugs include sulfasalazine, plaquenil, and other

preparations.

These agents differ from non-steroidal anti-inflammatory drugs (NSAIDs) in

their delayed onset of action and lack of ability to provide pain relief.

They are thought to be capable of modifying the disease and have been known

to induce remission of the disease. Preventing joint damage and controlling

inflammation is the goal of treatment in RA. Drugs that are being used

currently only partially and temporarily control inflammation. Because when

drugs are used alone, effectiveness is short lived and therefore drugs are

used in combination.

The need for effective therapy of RA is clear to physicians who treat RA.

Although current drugs may be used in combination are used to control

inflammation, studies are being performed to find drugs that will be more

effective and less toxic.

New methods and treatments for RA will most likely bring about earlier

recognition of the disease, earlier interventions, and new therapies. Until

a cure is available, it is suggested that current and future therapies be

evaluated carefully for their effectiveness. Frequent follow-up is

recommended to ensure proper treatment and to minimize the debilitating

effects RA can have on the patient.

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