Prevention of Inflammatory Diseases

[Guest guest]

Hi folks:

I don't remember seeing this posted previously. My apologies if it

is a repeat:

" Suppression of the nuclear factor-kappaB activation pathway by spice-

derived phytochemicals: reasoning for seasoning.

Aggarwal BB, Shishodia S.

Cytokine Research Laboratory, Department of Experimental

Therapeutics, The University of Texas M.D. Cancer Center,

Box 143, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

The activation of nuclear transcription factor kappaB has now been

linked with a variety of inflammatory diseases, including cancer,

atherosclerosis, myocardial infarction, diabetes, allergy, asthma,

arthritis, Crohn's disease, multiple sclerosis, Alzheimer's disease,

osteoporosis, psoriasis, septic shock, and AIDS. Extensive research

in the last few years has shown that the pathway that activates this

transcription factor can be interrupted by phytochemicals derived

from spices such as turmeric (curcumin), red pepper (capsaicin),

cloves (eugenol), ginger (gingerol), cumin, anise, and fennel

(anethol), basil and rosemary (ursolic acid), garlic (diallyl

sulfide, S-allylmercaptocysteine, ajoene), and pomegranate (ellagic

acid). For the first time, therefore, research provides " reasoning

for seasoning. "

PMID: 15659827

Rodney.