Guest guest Posted December 14, 2007 Report Share Posted December 14, 2007 The issue of pH is still scientifically controversial. I have seen a number of papers that indicate that increasing pH (alkalinization) of body fluids may reduce the incidence of cancer. The Mayo clinic discounts this alternative therapy: " Alkaline diet. A diet rich in certain alkaline foods, meaning foods that aren't acidic, won't cure cancer. Proponents of this diet claim foods such as soft drinks and meats make your body acidic, allowing cancer to flourish. They suggest eating mainly alkaline foods, such as fruits and vegetables, and restricting acidic foods. The theory that acid causes cancer isn't true, and it isn't clear that what you eat has any impact on your body's overall acidity or alkalinity. " [1] However, there seems to be new research that offers an explanation about why alkalinity could prevent cancer by enhancing the mechanism for apoptosis: " A novel signaling pathway triggered by DNA damage leads to the upregulation of the NHE-1 antiport, increased intracellular pH, Bcl-xL deamidation, and finally apoptosis. " [2] It is possible that pH is another factor that we have to consider in our quest for Optimum Nutrition. Tony [1] http://www.mayoclinic.com/health/cancer-treatment/CM00002 [2] http://dx.doi.org/10.1371/journal.pbio.0050010 PLoS Biol. 2007 January; 5(1): e10. Published online 2006 December 19. doi: 10.1371/journal.pbio.0050010. Manipulating Cellular pH Suggests Novel Anticancer Therapy Liza Gross " In the 1920s, when the genetic theory of cancer was taking root, German biochemist Otto Warburg (winner of the 1931 Nobel prize in physiology or medicine) proposed that abnormal energy metabolism caused cancer. Cells can generate energy either through oxidative respiration in mitochondria or through glycolysis in the cytoplasm. Warburg showed that tumors have an acidic extracellular environment, and he argued that a switch from oxidative respiration to glycolysis—which produces lactic acid—sets the cell down the path to cancer. Though most cancer researchers think this glycolytic shift is a by-product rather than a cause of cancer, Warburg's work stimulated interest in the possibility that there was some kind of link between pH and cancer. And now, a new study by Rui Zhao, Denis , and colleagues shows why manipulating the intracellular pH of tumor cells may indeed turn out to be a promising anticancer strategy. [... snip...] Though Warburg's metabolic theory of cancer never gained traction, his work highlighted a possible connection between pH and cancer—and now, 70 years later, that link is receiving experimental support. Many different tumor types appear to use Bcl-xL to bypass apoptosis, rendering some cancer cells resistant to therapy. This suggests that inducing alkalinization—possibly by enhancing NHE-1 expression or increasing its activity—to promote Bcl-xL deamidation and thus apoptosis may prove an effective strategy to treat a range of cancers. " > > Given that pH is actually a measure of positive ion concentration > (inverse logarithmic), do acid-forming foods (i.e. high concentration > of positive ions) act biologically as as oxidants, while alkaline > foods act as antioxidants? This would seem to be a scientific basis > for the philosophy of eating alkaline foods and largely avoiding > acidic foods, in spite of the fact that the human body is capable of > maintaining a relatively narrow range in pH. Does anyone have a more > detailed knowledge of this issue? > > Thanks, > -Dave > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2007 Report Share Posted December 15, 2007 Thanks, Tony, Just a question, How would I know my PH - where measured? Regards [ ] Re: Acidic/Alkaline and Oxidant/Antioxidant It is possible that pH is another factor that we haveto consider in our quest for Optimum Nutrition.Tony Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 16, 2007 Report Share Posted December 16, 2007 Saliva and urine are the fluids normally tested for pH. Many pharmacies carry pH test strips. You can also buy them over the Internet, e.g., http://www.ph-ion.com/index.asp?PageAction=VIEWCATS & Category=205 The website above has a lot of statements about alkaline diet which do not have much scientific support. Caveat lector. Tony > > Thanks, Tony, > Just a question, How would I know my PH - where measured? > > Regards > > [ ] Re: Acidic/Alkaline and Oxidant/Antioxidant > > > > It is possible that pH is another factor that we have > to consider in our quest for Optimum Nutrition. > > Tony > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 16, 2007 Report Share Posted December 16, 2007 Hi folks: And since the environment in the stomach is quite strongly acidic - in the form of hydrochloric acid, presumably in the interests of effective digestion - it seems doubtful to me that when the food exits the stomach it makes any difference what its pH had been originally. Rodney. ........................................... > The website above has a lot of statements about alkaline diet which do > not have much scientific support. Caveat lector. > > Tony > > --- In , " jwwright " <jwwright@> wrote: > > > > Thanks, Tony, > > Just a question, How would I know my PH - where measured? > > > > Regards > > > > Re: Acidic/Alkaline and Oxidant/Antioxidant > > > > It is possible that pH is another factor that we have > > to consider in our quest for Optimum Nutrition. > > > > Tony Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2007 Report Share Posted December 17, 2007 Rodney, You are right that stomach acid will change the pH of the food that you eat. However, the buffering capacity of the body is eventually affected by what is ingested and the pH of the body fluids will shift. Sodium bicarbonate (baking soda) and other alkalinization agents have been used to shift the pH of the urine and promote the elimination of uric acid which causes stones, tophi, and gout when it crystallizes in the tissues.[1] Tony [1] Marangella M., Uric acid elimination in the urine. Pathophysiological implications. Contrib Nephrol. 2005;147:132-48. Uric acid nephrolithiasis results from supersaturation, strongly influenced by low urine pH, rather than altered urate turnover. Alkali and fluid intake prove successful in managing uric acid stones. PMID: 15604613 More information about gout: http://scientificpsychic.com/health/gout.html > > > > > > Thanks, Tony, > > > Just a question, How would I know my PH - where measured? > > > > > > Regards > > > > > > Re: Acidic/Alkaline and Oxidant/Antioxidant > > > > > > It is possible that pH is another factor that we have > > > to consider in our quest for Optimum Nutrition. > > > > > > Tony > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 Rodney: If this were true, would it not also nullify the beneficial effects of antioxidants? In other words, would it matter at all whether we consume foods high in oxidants vs. antioxidants? -Dave > > > > > > Thanks, Tony, > > > Just a question, How would I know my PH - where measured? > > > > > > Regards > > > > > > Re: Acidic/Alkaline and Oxidant/Antioxidant > > > > > > It is possible that pH is another factor that we have > > > to consider in our quest for Optimum Nutrition. > > > > > > Tony > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 HCL is a strong oxidizer and yes a lot of stuff gets changed, into chlorides. That's why many of your medications end in a hydrochloride - designed to get thru the digestion. Regards [ ] Re: Acidic/Alkaline and Oxidant/Antioxidant Rodney:If this were true, would it not also nullifythe beneficial effects of antioxidants? In otherwords, would it matter at all whether we consumefoods high in oxidants vs. antioxidants?-Dave>> Hi folks:> > And since the environment in the stomach is quite strongly acidic - > in the form of hydrochloric acid, presumably in the interests of > effective digestion - it seems doubtful to me that when the food > exits the stomach it makes any difference what its pH had been > originally.> > Rodney.> .. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 Hi Dave: Clearly when the food that enters the digestive tract is deluged by all kinds of chemicals and microbes in the mouth, the stomach and the gut in order to make it absorbable, the stuff that gets absorbed will not be identical to what was originally put in the mouth. Presumably this varies for each ingested component. Some will remain unchanged through this process, while others will not. In addition, different individuals have different processing capability for different nutrients, lactose intolerance for example. And also different absorption rates .... one person here reported having a low serum 25(OH)D level while consuming substantial amounts of it. So I like to look at the data from *empirical* studies which try to assess the effects of consumption of different foods/nutrients. If the studies show that a given food helps then I try to pay attention to it. But since we are all different, the findings may not, of course, apply to me. I am not sure there is a better way, as yet, but I am 'all ears' to suggestions. This is a reason why blood tests for nutrient adequacy are helpful. Rodney. > > > > > > > > Thanks, Tony, > > > > Just a question, How would I know my PH - where measured? > > > > > > > > Regards > > > > > > > > Re: Acidic/Alkaline and Oxidant/Antioxidant > > > > > > > > It is possible that pH is another factor that we have > > > > to consider in our quest for Optimum Nutrition. > > > > > > > > Tony > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 While I certainly won't ignore the fact that nutritional needs, nutrient absorption, etc. vary from person to person, clearly general nutritional recommendations have come to light through a combination of theoretical & experimental work, and epidemiological, and controlled studies. For example, we know that it is a good idea to avoid too much saturated fat, sodium, trans fatty acids, etc. If acidic foods biologically act as oxidants, then would it not be a good idea to limit consumption of those as well? So the question remains: Do acidic foods act as oxidants?? > > > > > > > > > > Thanks, Tony, > > > > > Just a question, How would I know my PH - where measured? > > > > > > > > > > Regards > > > > > > > > > > Re: Acidic/Alkaline and Oxidant/Antioxidant > > > > > > > > > > It is possible that pH is another factor that we have > > > > > to consider in our quest for Optimum Nutrition. > > > > > > > > > > Tony > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2007 Report Share Posted December 19, 2007 Hi Dave: I dunno, and it may vary from one acidic food to another. I personally rely on the results of large studies that have found benefits from a specific food for the majority of study subjects. But as we know, not infrequently the results of one study are contradicted by the next. And what applies to the majority sometimes will not apply to you or me as individuals. This remains a very inexact science. But is there reason to believe, for example, that those who use larger than average amounts of vinegar, lemon juice, vitamin C or wine have problems related to lack of anti-oxidants ............ cancer, maybe? Not that I know of, but has anyone checked? Rodney. .......................................... > Do acidic foods act as oxidants?? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2007 Report Share Posted December 19, 2007 Rodney: Yet another complication is the differentiation between acidity of the food itself and the acid-producing effects when utilized by our digestive system. For example, lemon juice and Vitamin C are not acid forming, while other more acidic foods, such as fermented ones, and many animal products, are. Then there is also the complication of some acidic foods, such as wine, having enormous amounts of antioxidants. Yes, certainly heavy wine drinking has been correlated with increased cancer risk, but that is true of alcohol in general. So, I should clarify: I am referring to acid-forming foods being unhealthy (not mildly acidic foods that are not acid-forming). -Dave > > ......................................... > > Do acidic foods act as oxidants?? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2007 Report Share Posted December 19, 2007 Dave, What you are saying does not make sense. I think that you need to brush up on your chemistry and biochemistry. Your statement that " Vitamin C is not acid forming " is hogwash. Vitamin C itself is an acid (ascorbic acid). http://en.wikipedia.org/wiki/Vitamin_C http://en.wikipedia.org/wiki/Ascorbic_acid Here is a page with a basic chemistry glossary: http://scientificpsychic.com/health/chemistry.html The biochemistry of metabolism is quite complex. Many aspects of metabolism are described in the Medical Biochemistry Page: http://web.indstate.edu/thcme/mwking/home.html For example, the metabolism of glucose (glycolysis) is described here: http://web.indstate.edu/thcme/mwking/glycolysis.html This page describes what happens when you eat carbohydrates. Your statements that fermented foods and animal products are more acidic has no basis whatsoever in science. If you really want to know how the body really works, please read the Medical Biochemistry Page from start to finish. Tony Zamora > > > > ......................................... > > > Do acidic foods act as oxidants?? > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2007 Report Share Posted December 20, 2007 Hi Tony. I suggest that you research which foods are acid-FORMING. For example, lemons are not acid-forming, although coffee is. The end result after the interaction with our digestive system is what is important. There are many sources and charts of alkaline/acidic foods all over the internet and elsewhere. Here is one from Life Extension Magazine (you'll need to scroll down some to get to the chart) http://www.lef.org/protocols/prtcl-017a.shtml Thanks, -Dave > > > > > > ......................................... > > > > Do acidic foods act as oxidants?? > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2007 Report Share Posted December 20, 2007 Dave, The reference that you provide in lef.org lists the same kind of information that is being advocated by some popular books like the " The pH Miracle: Balance Your Diet, Reclaim Your Health " , " The Acid-Alkaline Food Guide: A Quick Reference to Foods & Their Effect on pH Levels " , and other books now in vogue. I don't think that the claims made by any of these books have been substantiated. If you are so sure that this information is valid please provide some references from reputable scientific journals. As a starter, just provide ONE reference from PubMed that shows that lemons are not acid-forming or that shows that olive oil is an acidifying food. If you are able to produce such references, I will consider this more seriously, otherwise I will continue to contend that most of the advice about pH is just baloney. Here is just one of the statements in your lef.org citation that makes me dubious: " Allergic reactions and other forms of stress tend to produce acids in the body. " Really? In what part of the body? By what mechanism? What are the chemical reactions involved? People make up all kinds of stuff to sell books and worthless nutritional supplements. This is not science. This is pseudoscientific mythology. Tony > > > > > > Rodney: > > > > > > Yet another complication is the differentiation between acidity of the > > > food itself and the acid-producing effects when utilized by our > > > digestive system. For example, lemon juice and Vitamin C are not acid > > > forming, while other more acidic foods, such as fermented ones, and > > > many animal products, are. > > > > > > Then there is also the complication of some acidic foods, such as > > > wine, having enormous amounts of antioxidants. Yes, certainly heavy > > > wine drinking has been correlated with increased cancer risk, but that > > > is true of alcohol in general. > > > > > > So, I should clarify: I am referring to acid-forming foods being > > > unhealthy (not mildly acidic foods that are not acid-forming). > > > > > > -Dave > > > > > > --- In , " Rodney " <perspect1111@> wrote: > > > > > > > > Hi Dave: > > > > > > > > I dunno, and it may vary from one acidic food to another. I > > > > personally rely on the results of large studies that have found > > > > benefits from a specific food for the majority of study subjects. > > But > > > > as we know, not infrequently the results of one study are > > contradicted > > > > by the next. And what applies to the majority sometimes will not > > > > apply to you or me as individuals. This remains a very inexact > > > > science. > > > > > > > > But is there reason to believe, for example, that those who use > > larger > > > > than average amounts of vinegar, lemon juice, vitamin C or wine > have > > > > problems related to lack of anti-oxidants ............ cancer, > > > > maybe? Not that I know of, but has anyone checked? > > > > > > > > Rodney. > > > > > > > > --- In , " orb85750 " <orb85750@> wrote: > > > > > > > > ......................................... > > > > > Do acidic foods act as oxidants?? > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2007 Report Share Posted December 20, 2007 Hi Dave and Tony: This raises a million questions in my mind. If this issue is for real what does it mean? Does it mean that if you eat olive oil your blood and/or urine will be more acidic than if you don't? And if it does mean that, where is the evidence? And if there is evidence for it, then what is the evidence that having higher or lower blood or urine pH is beneficial or harmful? Who did the tests of all these foods to determine if they are " acid- forming " or " alkali-forming " ? And how were the tests conducted? There is a fair amount of research about the measurement of the glycemic index of various foods, for example, which has been posted here more than once. And even with that evidence there remains far from full agreement about the usefulness of GI! So where is the equivalent research documenting the claimed " acid-forming " effects of the ingestion of different foods? Clearly, without such references one has to ask on the basis of what information were the lists of foods you linked compiled? This SOUNDS to me like a lot of " baloney " as Tony suggested, propogated in the interests of selling snake oil. I am willing to change my mind if shown the type of information which around here is regarded as " serious evidence " . But without it I will continue to consider it to be snake oil. Rodney. > > > > > > > > > > ......................................... > > > > > > Do acidic foods act as oxidants?? > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2007 Report Share Posted December 20, 2007 Tony: It is important to note that in the FDA list of food pH levels, shown here http://www.cfsan.fda.gov/~comm/lacf-phs.html most of the fruits (and even many vegetables) are much more acidic than most of the animal/meat products listed. However, please see this study from PubMed that shows opposite results with respect to resulting urine pH of test subjects: ----------- " Urine pH is an indicator of dietary acid-base load, fruit and vegetables and meat intakes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk population study. " Welch AA, Mulligan A, Bingham SA, Khaw KT. Department of Public Health and Primary Care, University of Cambridge, Strangeways Site, Wort's Causeway, Cambridge CB1 8RN, UK. Evidence exists that a more acidic diet is detrimental to bone health. Although more precise methods exist for measurement of acid-base balance, urine pH reflects acid-base balance and is readily measurable but has not been related to habitual dietary intake in general populations. The present study investigated the relationship between urine pH and dietary acid-base load (potential renal acid load; PRAL) and its contributory food groups (fruit and vegetables, meats, cereal and dairy foods). There were 22 034 men and women aged 39-78 years living in Norfolk (UK) with casual urine samples and dietary intakes from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk FFQ. A sub-study (n 363) compared pH in casual samples and 24 h urine and intakes from a 7 d diary and the FFQ. A more alkaline diet (low PRAL), high fruit and vegetable intake and lower consumption of meat was significantly associated with a more alkaline urine pH before and after adjustment for age, BMI, physical activity and smoking habit and also after excluding for urinary protein, glucose, ketones, diagnosed high blood pressure and diuretic medication. In the sub-study the strongest relationship was found between the 24 h urine and the 7 d diary. In conclusion, a more alkaline diet, higher fruit and vegetable and lower meat intake were related to more alkaline urine with a magnitude similar to intervention studies. As urine pH relates to dietary acid-base load its use to monitor change in consumption of fruit and vegetables, in individuals, warrants further investigation. PMID: 18042305 [PubMed - as supplied by publisher] ----------- *Higher* fruit and vegetable intake relative to meat consumption clearly resulted in *less* acidic urine in test subjects. So, a more acidic food clearly can be less acid-forming than a less-acidic food once the digestive system has acted on it, right? -Dave > > > > > > > > > > ......................................... > > > > > > Do acidic foods act as oxidants?? > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2007 Report Share Posted December 21, 2007 Hi Dave: Thank you for that paper. It agrees with your view that urine pH will vary depending on foods eaten. And that the acidity of the food is not well correlated with the resulting acidity of urine. This is the first information I have seen about this issue. So it would be nice, if possible, to see data from studies done by other investigators that confirm this. The investigators do not conclude that there are major health consequences. Rather they seem to be speculating that testing urine pH might be a good way to confirm the validity of stated food intakes of study subjects. Assuming this is confirmed, the remaining issue is the health implications. The only consequence they mention is lower bone mass in females, but not males, with higher urine pH. According to the following paper, by many of the same authors, the bone mass effect is not large. It appears to be 2% different for extreme quintiles of urine pH. As previously noted here, the 'normal' seasonal variation in bone mass at higher latitudes appears to be more than four times greater than this. Nevertheless that is an interesting finding. PMID: 17413116 " More acidic dietary acid-base load is associated with reduced calcaneal broadband ultrasound attenuation in women but not in men: results from the EPIC-Norfolk cohort study. " Welch AA, Bingham SA, Reeve J, Khaw KT. " CONCLUSION: PRAL (potential renal acid load) was inversely associated with bone ultrasound measures in women, but the magnitude of the association was relatively small compared with other known risk factors. Further longitudinal studies are required to establish whether, in the long term, these small effects are important in overall fracture risk in populations. " If there are additional health consequences of more, or less, acidic urine, beyond bone mass effects, it would be interesting to know what they are. It would also be helpful to know the source of the data for the 'acid-forming' foods contained in the links you had posted earlier. My impression is that most people on CRON eat a predominantly plant- based diet. So this is another encouraging piece of information supporting what many of us regard as the 'ON' part of CRON. Rodney. > > > > > > > > > > > > ......................................... > > > > > > > Do acidic foods act as oxidants?? > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2007 Report Share Posted December 21, 2007 Hi Dave: I just checked my most recent lab results and see that my urinary pH was 7·5, against a reference range of 5·0 to 8·0. Makes sense since I am not totally vegetarian. Rodney. > > > > > > > > > > > > > > ......................................... > > > > > > > > Do acidic foods act as oxidants?? > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2007 Report Share Posted December 22, 2007 Hi folks: Quick correction: Where I said " higher urine pH " , below, I of course meant " lower urine pH " . Oooops. Sorry about that. Rodney. --- In , " Rodney " <perspect1111@...> wrote: > Hi Dave: > ............................................ > Assuming this is confirmed, the remaining issue is the health > implications. The only consequence they mention is lower bone > mass in females, but not males, with higher urine pH. ................................. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2007 Report Share Posted December 22, 2007 Dave, PMID 18042305 is the type of reference that helps to understand the topic better. The abstract defines an alkaline diet as a low PRAL (potential renal acid load) diet. Foods that increase the [uric] acid load on the kidneys are considered " acid " foods. This would include nitrogen-containing foods (proteins and nucleic acids), but not oils or carbohydrates because they have no nitrogen. Using this definition is how fruits and vegetables which have a lower pH (more acidic) end up in the " alkaline " category, whereas meat, dairy, and legumes which are protein-rich are categorized as " acidic " . The categorization of oils, such as olive oil, as " acid foods " in the lef.org web site still does not make sense since oils do not increase renal acid load. Item related to bone loss: I recently saw a forensic anthropology program where they discovered some remains with bones that showed a lot of demineralization. The investigation concluded that the people died of scurvy. It turns out that ascorbic acid (Vitamin C) mediates collagen synthesis[1], and collagen is the protein that holds the bone minerals, mostly calcium phosphate crystals, together. Tony [1] PMID: 15951132 Med Hypotheses. 2005;65(3):426-32. Osteoporosis, a unitary hypothesis of collagen loss in skin and bone. Shuster S. > > > > Tony: > > > > It is important to note that in the FDA list of food > > pH levels, shown here > > > > http://www.cfsan.fda.gov/~comm/lacf-phs.html > > > > most of the fruits (and even many vegetables) are much more acidic > > than most of the animal/meat products listed. However, > > please see this study from PubMed that shows opposite results with > > respect to resulting urine pH of test subjects: > > ----------- > > " Urine pH is an indicator of dietary acid-base load, fruit and > > vegetables and meat intakes: results from the European Prospective > > Investigation into Cancer and Nutrition (EPIC)-Norfolk population > study. " > > Welch AA, Mulligan A, Bingham SA, Khaw KT. > > > > Department of Public Health and Primary Care, University of > Cambridge, > > Strangeways Site, Wort's Causeway, Cambridge CB1 8RN, UK. > > > > Evidence exists that a more acidic diet is detrimental to bone > health. > > Although more precise methods exist for measurement of acid-base > > balance, urine pH reflects acid-base balance and is readily > measurable > > but has not been related to habitual dietary intake in general > > populations. The present study investigated the relationship > between > > urine pH and dietary acid-base load (potential renal acid load; > PRAL) > > and its contributory food groups (fruit and vegetables, meats, > cereal > > and dairy foods). There were 22 034 men and women aged 39-78 years > > living in Norfolk (UK) with casual urine samples and dietary > intakes > > from the European Prospective Investigation into Cancer and > Nutrition > > (EPIC)-Norfolk FFQ. A sub-study (n 363) compared pH in casual > samples > > and 24 h urine and intakes from a 7 d diary and the FFQ. A more > > alkaline diet (low PRAL), high fruit and vegetable intake and lower > > consumption of meat was significantly associated with a more > alkaline > > urine pH before and after adjustment for age, BMI, physical > activity > > and smoking habit and also after excluding for urinary protein, > > glucose, ketones, diagnosed high blood pressure and diuretic > > medication. In the sub-study the strongest relationship was found > > between the 24 h urine and the 7 d diary. In conclusion, a more > > alkaline diet, higher fruit and vegetable and lower meat intake > were > > related to more alkaline urine with a magnitude similar to > > intervention studies. As urine pH relates to dietary acid-base load > > its use to monitor change in consumption of fruit and vegetables, > in > > individuals, warrants further investigation. > > PMID: 18042305 [PubMed - as supplied by publisher] > > ----------- > > > > *Higher* fruit and vegetable intake relative > > to meat consumption clearly resulted in *less* acidic > > urine in test subjects. So, a more acidic food clearly can be > > less acid-forming than a less-acidic food once the digestive > > system has acted on it, right? > > > > -Dave > > > > Quote Link to comment Share on other sites More sharing options...
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