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Re: Fructose >>> Gout ???

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The researchers may have blamed the wrong component of the soft drink

if they did not take into consideration the caffeine content and

acidity of the drinks. Caffeine is a purine which is oxidized to uric

acid thus increasing the potential for gout. Another reason for the

increased gout could be the acidity of the soft drinks. Decreases in

the pH of body fluids by ingredients such as phosphoric acid in the

soft drinks reduce the solubility of uric acid and may cause

demineralization of teeth and bones.

Fructose may just be an innocent bystander.

Some uric acid chemistry and gout information:

http://www.scientificpsychic.com/health/gout.html

Tony

>

> http://news.bbc.co.uk/2/hi/health/7219473.stm

>

> And the link seems not only to be associated with HFCS, either.

>

> Rodney.

>

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Hi All, The pdf is availed. Cheers, Al RESEARCH:Hyon K Choi and CurhanSoft drinks, fructose consumption, and the risk of gout in men: prospective cohort studyBMJ, Jan 2008 Objective To examine the relation between intake of sugar sweetened soft drinks and fructose and the risk of incident gout in men. Design Prospective cohort over 12 years. Setting Health professionals follow-up study. Participants 46 393 men with no history of gout at baseline who provided information on intake of soft drinks and fructose through validated food frequency questionnaires. Main outcome measure Incident cases of gout meeting the American College of Rheumatology survey criteria for gout. Results During the 12 years

of follow-up 755 confirmed incident cases of gout were reported. Increasing intake of sugar sweetened soft drinks was associated with an increasing risk of gout. Compared with consumption of less than one serving of sugar sweetened soft drinks a month the multivariate relative risk of gout for 5-6 servings a week was 1.29 (95% confidence interval 1.00 to 1.68), for one serving a day was 1.45 (1.02 to 2.08), and for two or more servings a day was 1.85 (1.08 to 3.16; P for trend=0.002). Diet soft drinks were not associated with risk of gout (P for trend=0.99). The multivariate relative risk of gout according to increasing fifths of fructose intake were 1.00, 1.29, 1.41, 1.84, and 2.02 (1.49 to 2.75; P for trend <0.001). Other major contributors to fructose intake such as total fruit juice or fructose rich fruits (apples and oranges) were also associated with a higher risk of gout (P values for trend <0.05). Conclusions Prospective data

suggest that consumption of sugar sweetened soft drinks and fructose is strongly associated with an increased risk of gout in men. Furthermore, fructose rich fruits and fruit juices may also increase the risk. Diet soft drinks were not associated with the risk of gout.Rodney <perspect1111@...> wrote: http://news.bbc.co.uk/2/hi/health/7219473.stmAnd the link seems not only to be associated with HFCS,

either.Rodney.

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Hi All, "Sugar sweetened soft drinks and incident gout Increasing intake of sugar sweetened soft drinks was associated with an increasing risk of gout (table 2). Compared with the reference consumption level of less than one serving a month, the multivariate relative risk of gout for 5-6 servings a week was 1.29 (95% confidence interval 1.00 to 1.68), for one serving a day was 1.45 (1.02 to 2.08), and for two or more servings a day was 1.85 (1.08 to 3.16; P for trend 0.002). In contrast, diet soft drinks were not associated with risk of gout (P for trend 0.99). When additional adjustments were made for caffeine or coffee intake, these results did not change materially. After adjusting for fructose in intakes of fifths, however, the association between the intake of sugar sweetened soft drinks and risk of gout was attenuated and no longer significant (P for

trend 0.10)." Cheers, Alcitpeks <citpeks@...> wrote: The researchers may have blamed the wrong component of the soft drinkif they did not take into consideration the caffeine content andacidity of the drinks. Caffeine is a purine which is oxidized to uricacid thus increasing the potential for gout. Another reason for theincreased gout could be the acidity of the soft drinks. Decreases inthe pH of body fluids by ingredients such as phosphoric acid in thesoft drinks reduce the

solubility of uric acid and may causedemineralization of teeth and bones.Fructose may just be an innocent bystander.Some uric acid chemistry and gout information:http://www.scientificpsychic.com/health/gout.htmlTony--- In , "Rodney" <perspect1111@...> wrote:>> http://news.bbc.co.uk/2/hi/health/7219473.stm> > And the link seems not only to be associated with HFCS, either.> > Rodney.>

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Folks: please include a snippet of the post you are replying to. Otherwise others will have trouble following the thread.

Thanks to all for your future cooperation.

From: Don <white69@...>

Reply-< >

Date: Sat, 02 Feb 2008 14:11:29 -0000

< >

Subject: [ ] Fructose >>> Gout ???

The PH of a given soft drink is the same whether it is diet or

regular. The quantity of phosphoric acid in a soda is so small, it has

a miniscule impact on the overall acidity of the soda, which is about

3. This comes from carbonic acid, which is part of the carbonation

process, or the bubbling if you will.

The stomach PH, being basically 1, would be unaffected by the soft

drink. If you drink enough, the stomach will turn on it's acid

generators, and more acid with a PH of 1 arrives.

Looks like the sugar that is in regular soft drinks, and isn't in diet

softdrinks, is probably the culprit.

Don White

Seguin, Tx

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Hi All, The frucose in fruit also associated with gout, in the pdf-availed paper. Cheers, Al PaterDon <white69@...> wrote: The PH of a given soft drink is the same whether it is diet orregular. The quantity of phosphoric acid in a soda is so small, it hasa miniscule impact on the overall acidity of the soda, which is about3. This comes from carbonic acid, which is part of the carbonationprocess, or the bubbling if you will. The stomach PH, being

basically 1, would be unaffected by the softdrink. If you drink enough, the stomach will turn on it's acidgenerators, and more acid with a PH of 1 arrives. Looks like the sugar that is in regular soft drinks, and isn't in dietsoftdrinks, is probably the culprit. Don WhiteSeguin, Tx

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