Re: Re: Selenium Supplements May Raise Diabetes Risk by 50%

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The source of Selenium also should skew the results reported. Selenium present in multivitamin tablets is present as a salt with other mineral salts. Plant sourced Selenium is acceptable from fruits and vegetables because it is in a bio-ready ionic form. There is a liquid multivitamin, with essential minerals(plant sourced phytonutrients) in ionic form combined with mangosteen and aloe. It is called Vemma. For info link www.vemma.com and www.myvemma.com/maxvem1 . Thank me later, bill4cr <bill4cr@...> wrote: More info:Selenium Supplements May Increase The Risk Of Type 2 DiabetesScience Daily — Selenium, an antioxidant included in multivitamintablets thought to have a possible protective effect against thedevelopment of type 2 diabetes, may actually increase the risk ofdeveloping the disease, an analysis by researchers at the Universityat Buffalo has shown.Results of a randomized clinical trial using 200 micrograms ofselenium alone showed that 55 percent more cases of type 2 diabetesdeveloped among participants randomized to receive selenium than inthose who received a placebo pill.Results will appear in print in the

August 2007 issue of ls ofInternal Medicine and were posted online on July 10.Self-reported diagnosis of type 2 diabetes was a secondary endpoint ina clinical trial designed to test the benefit of seleniumsupplementation in prevention of non-melanoma skin cancer in areas inthe Eastern U.S. where selenium levels are lower than the nationalaverage. Selenium is a trace mineral that is an essential component ofproteins involved in antioxidant activity.Saverio Stranges, M.D., Ph.D., first author on the diabetes preventionstudy, conducted the analysis while at UB, in cooperation withcolleagues from Roswell Park Cancer Institute. He now is affiliatedwith the Clinical Sciences Research Institute, Warwick Medical School,Coventry, UK.Stranges said the findings are very interesting, but should beconsidered cautiously."Among participants taking selenium supplementation, those who had thehighest levels

of selenium in their circulation at the beginning ofthe study had the highest risk of developing type 2 diabetes over theaverage 7.7 years of follow-up," he said, "and the increase in risk isunlikely to be a result of chance."However, in the general population, very few people, if any, takeselenium supplements only, every day, for nearly eight years, so wecan't be sure that these findings apply to the public at large."Perhaps the more important message is that a large proportion of theU.S. population, about 50 percent, takes multivitamins, even thoughthere is no evidence that taking multivitamins helps prevent chronicdisease among healthy people. In this country, we can get all theantioxidants we need in fruits and vegetables, but it's easier to takea vitamin than to eat a more healthy diet."The selenium and diabetes study involved 1,202 people who did not havetype 2 diabetes when they entered the cancer

clinical trial at RoswellPark. Participants had been recruited for the main study between 1983and 1991, and they were involved for an average of 7.7 years. Thesupplementation study was completed in February 1996.Analysis for this diabetes study involved data from 600 persons whohad taken selenium and 602 who were randomized to receive placebo pills.Results showed that 97 participants developed type 2 diabetes duringthe study period, 58 in the selenium group and 39 in the placebogroup. There was no difference in the findings when age, sex, smokingstatus and body mass index were included in the analysis."At the moment we don't know what mechanism or mechanisms account forthis finding," said Stranges. "We have very little understanding ofthe possible biological pathways involved. In addition, our findingsneed to be replicated in larger clinical trials before conclusiveevidence can be drawn on whether high

doses of selenium supplementsincrease the risk of type 2 diabetes, as our study suggests."With selenium, which is a trace element, it may be the case that alittle bit is essential, but more can cause detrimental effects, atleast in well-nourished populations such as the U.S. It's possiblethat taking extra selenium overcomes the natural balance. Perhapsexcess selenium has a negative effect on the endocrine system."Additional authors are R. Marshal, Ph.D., Raj Natarajan, and E. Reid, Ph.D., from Roswell Park; P. Donahue, Ph.D., andMaurizio Trevisan, M.D, from the UB School of Public Health and HealthProfessions; Gerald F. Combs, Ph.D., from the Human Nutrition ResearchCenter, Grand Forks, N.D.; and Francesco P. Cappuccio, M.D., and Ceriello, M.D., from Warwick Medical School, UK.Note: This story has been adapted from a news release issued byUniversity at Buffalo.> > > > > > > > >> > > > > > > > > http://www.abcnews.go.com/Health/Diabetes/story?> > > > > > id=3360328 & page=1> > > > > > > > > > > > > > > > > > ..and here i thought selenium was one of a few that > may > > be > > > > > > better to> > > > > > > > > supplement > > > > > > > > > > > > > > > > > > Once again, seems best to consume your vitamins in > > their > > > > natural> > > > > > > > > package > > > > > > > > > > > > > > > > > > "Researchers selected more than 1,200 participants > from > > the > > > > > > study who> > > > > >

> > > were initially diabetes-free. Half took a 200-> microgram > > > > selenium> > > > > > > > > supplement daily for an average of nearly eight > years, > > > > while > > > > > > half> > > > > > > > > received a placebo pill over the same duration.> > > > > > > > > > > > > > > > > > What researchers found was that those taking the > actual > > > > selenium> > > > > > > > > supplements actually increased their risk of > developing > > > > type II> > > > > > > > > diabetes by about 50 percent."> > > > > > > > >> > > > > > > >> > > > > > >> > > > > >> >

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