More support for lycopene's prostate benefits

[Guest guest]

Men with BPH but no signs of prostate cancer received either daily

lycopene supplements (15 mg) or placebo for six months.

At the end of the six month intervention period, levels of

prostate-specific antigen (PSA), a marker of prostate health, were

reduced in the lycopene group

++++++++++++++++

Link:

http://www.nutraingredients.com/news/ng.asp?n=82423 & m=1NIE109 & c=lqeudkujayvvlpc

full text:

More support for lycopene's prostate benefits

By ls

09/01/2008- Lycopene may show benefits against benign prostate

hyperplasia (BPH), a condition said to affect more than half of all men

over the age of 50, suggests a new study from Germany.

Forty people took part in the new pilot study, which adds clinical data

to an area previously lacking, according to the researchers in this

month's Journal of Nutrition.

Epidemiological evidence has suggested that tomato-based foods can

protect men from prostate cancer. One study found that men eating four

to five tomato based-dishes per week were 25 per cent less likely to

develop prostate cancer compared to men eating tomatoes only rarely.

Such findings are boosting the lycopene market, with growth rates

forecast at over 100 per cent by Frost and Sullivan, albeit from a low

base of around €27m ($34m) in 2003.

Researchers, led by Silke Schwarz from the University of Hohenheim,

recruited the men with BPH but no signs of prostate cancer, and

randomly assigned them to receive either daily lycopene supplements (15

mg) or placebo for six months.

Benign prostatic hyperplasia (BPH) is a non-cancerous swelling in the

prostate gland of older men. It affects approximately 25 per cent of

American Caucasians over the age of 50, with the direct cost of BPH in

2000 calculated to be $1.1 billion (€ 0.9 billion). According to the

European Association of Urology, 30 per cent of men older that 65 are

affected by BPH.

At the end of the six month intervention period, Schwarz and co-workers

reported that levels of prostate-specific antigen (PSA), a marker of

prostate health, were reduced in the lycopene group showing

improvements in health of the tissue. However, no changes were recorded

in the placebo group.

Moreover, no enlargement of the prostate occurred in the lycopene

group, whereas growth was observed in the placebo group, as assessed by

digital rectal examination and trans-rectal ultrasonography.

" Symptoms of the disease, as assessed via the International Prostate

Symptom Score questionnaire, were improved in both groups with a

significantly greater effect in men taking lycopene supplements, " wrote

the researchers.

" In conclusion, lycopene inhibited progression of BPH. "

The role of lycopene for prostate health has been questioned recently.

A study published last May in published in the journal Cancer

Epidemiology Biomarkers & Prevention, reported that the carotenoid may

not offer protection for prostates, based on a multi-centre study

case-control study including 692 prostate cancer cases, and 844

randomly selected, matched controls.

According to the European School of Oncology, over half a million news

cases of prostate cancer are diagnosed every year world wide, and the

cancer is the direct cause of over 200,000 deaths. More worryingly, the

incidence of the disease is increasing with a rise of 1.7 per cent over

15 years.

Source: Journal of Nutrition

January 2008, Volume 138, Pages 49-53

" Lycopene Inhibits Disease Progression in Patients with Benign Prostate

Hyperplasia "

Authors: S. Schwarz, U.C. Obermuller-Jevic, E. Hellmis, W. Koch, G.

i, H.-K. Biesalski

________________________________________________________________________________\

____

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Find them fast with Search.

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[Guest guest]

Hi folks:

Here is the abstract of this paper:

Lycopene inhibits disease progression in patients with benign

prostate hyperplasia.

Schwarz S, Obermüller-Jevic UC, Hellmis E, Koch W, i G,

Biesalski HK.

University of Hohenheim, Institute of Biological Chemistry and

Nutrition, 70593 Stuttgart, Germany.

Lycopene is a promising nutritional component for chemoprevention of

prostate cancer (PCa). A possibly beneficial role of lycopene in

patients diagnosed with benign prostate hyperplasia (BPH), who are

at increased risk of developing PCa, has been suggested, although

clinical data are lacking. Therefore, this pilot study aimed to

investigate the effects of lycopene supplementation in elderly men

diagnosed with BPH. A total of 40 patients with histologically

proven BPH free of PCa were randomized to receive either lycopene at

a dose of 15 mg/d or placebo for 6 mo. The effects of the

intervention on carotenoid status, clinical diagnostic markers of

prostate proliferation, and symptoms of the disease were assessed.

The primary endpoint of the study was the inhibition or reduction of

increased serum prostate-specific antigen (PSA) levels. The 6-mo

lycopene supplementation decreased PSA levels in men (P < 0.05),

whereas there was no change in the placebo group. The plasma

lycopene concentration increased in the group taking lycopene (P <

0.0001) but other plasma carotenoids were not affected. Whereas

progression of prostate enlargement occurred in the placebo group as

assessed by trans-rectal ultrasonography (P < 0.05) and digital

rectal examination (P < 0.01), the prostate did not enlarge in the

lycopene group. Symptoms of the disease, as assessed via the

International Prostate Symptom Score questionnaire, were improved in

both groups with a significantly greater effect in men taking

lycopene supplements. In conclusion, lycopene inhibited progression

of BPH.

PMID: 18156403

Rodney.

--- In , Dave Maddux <davemaddux@...>

wrote:

>

> Men with BPH but no signs of prostate cancer received either daily

> lycopene supplements (15 mg) or placebo for six months.

>

> At the end of the six month intervention period, levels of

> prostate-specific antigen (PSA), a marker of prostate health, were

> reduced in the lycopene group

>

>

> ++++++++++++++++

>

> Link:

>

> http://www.nutraingredients.com/news/ng.asp?

n=82423 & m=1NIE109 & c=lqeudkujayvvlpc

>

>

> full text:

>

> More support for lycopene's prostate benefits

>

> By ls

>

> 09/01/2008- Lycopene may show benefits against benign prostate

> hyperplasia (BPH), a condition said to affect more than half of

all men

> over the age of 50, suggests a new study from Germany.

>

> Forty people took part in the new pilot study, which adds clinical

data

> to an area previously lacking, according to the researchers in this

> month's Journal of Nutrition.

>

> Epidemiological evidence has suggested that tomato-based foods can

> protect men from prostate cancer. One study found that men eating

four

> to five tomato based-dishes per week were 25 per cent less likely

to

> develop prostate cancer compared to men eating tomatoes only

rarely.

>

> Such findings are boosting the lycopene market, with growth rates

> forecast at over 100 per cent by Frost and Sullivan, albeit from a

low

> base of around €27m ($34m) in 2003.

>

> Researchers, led by Silke Schwarz from the University of Hohenheim,

> recruited the men with BPH but no signs of prostate cancer, and

> randomly assigned them to receive either daily lycopene

supplements (15

> mg) or placebo for six months.

>

> Benign prostatic hyperplasia (BPH) is a non-cancerous swelling in

the

> prostate gland of older men. It affects approximately 25 per cent

of

> American Caucasians over the age of 50, with the direct cost of

BPH in

> 2000 calculated to be $1.1 billion (€ 0.9 billion). According to

the

> European Association of Urology, 30 per cent of men older that 65

are

> affected by BPH.

>

> At the end of the six month intervention period, Schwarz and co-

workers

> reported that levels of prostate-specific antigen (PSA), a marker

of

> prostate health, were reduced in the lycopene group showing

> improvements in health of the tissue. However, no changes were

recorded

> in the placebo group.

>

> Moreover, no enlargement of the prostate occurred in the lycopene

> group, whereas growth was observed in the placebo group, as

assessed by

> digital rectal examination and trans-rectal ultrasonography.

>

> " Symptoms of the disease, as assessed via the International

Prostate

> Symptom Score questionnaire, were improved in both groups with a

> significantly greater effect in men taking lycopene supplements, "

wrote

> the researchers.

>

> " In conclusion, lycopene inhibited progression of BPH. "

>

> The role of lycopene for prostate health has been questioned

recently.

> A study published last May in published in the journal Cancer

> Epidemiology Biomarkers & Prevention, reported that the carotenoid

may

> not offer protection for prostates, based on a multi-centre study

> case-control study including 692 prostate cancer cases, and 844

> randomly selected, matched controls.

>

> According to the European School of Oncology, over half a million

news

> cases of prostate cancer are diagnosed every year world wide, and

the

> cancer is the direct cause of over 200,000 deaths. More

worryingly, the

> incidence of the disease is increasing with a rise of 1.7 per cent

over

> 15 years.

>

> Source: Journal of Nutrition

> January 2008, Volume 138, Pages 49-53

> " Lycopene Inhibits Disease Progression in Patients with Benign

Prostate

> Hyperplasia "

> Authors: S. Schwarz, U.C. Obermuller-Jevic, E. Hellmis, W. Koch, G.

> i, H.-K. Biesalski

>

>

>

>

_____________________________________________________________________

_______________

> Looking for last minute shopping deals?

> Find them fast with Search.

http://tools.search./newsearch/category.php?

category=shopping

>

[Guest guest]

Lycopene is absorbed better if ingested as cooked tomatoes with a bit of fat – such as tomato sauce. Perhaps that’s another benefit of the “Mediterranean Diet”.

From: jwwright <jwwright@...>

Reply-< >

Date: Tue, 15 Jan 2008 09:57:39 -0800

< >, Rodney <perspect1111@...>

Subject: Re: [ ] Re: More support for lycopene's prostate benefits

I saw on tv that americans eat 67# of tomatoes per capita.

That oughta be enough lycopene?

Regerds

[ ] Re: More support for lycopene's prostate benefits

Hi folks:

Here is the abstract of this paper:

Lycopene inhibits disease progression in patients with benign

prostate hyperplasia.

Schwarz S, Obermüller-Jevic UC, Hellmis E, Koch W, i G,

Biesalski HK.

University of Hohenheim, Institute of Biological Chemistry and

Nutrition, 70593 Stuttgart, Germany.

Lycopene is a promising nutritional component for chemoprevention of

prostate cancer (PCa). A possibly beneficial role of lycopene in

patients diagnosed with benign prostate hyperplasia (BPH), who are

at increased risk of developing PCa, has been suggested, although

clinical data are lacking. Therefore, this pilot study aimed to

investigate the effects of lycopene supplementation in elderly men

diagnosed with BPH. A total of 40 patients with histologically

proven BPH free of PCa were randomized to receive either lycopene at

a dose of 15 mg/d or placebo for 6 mo. The effects of the

intervention on carotenoid status, clinical diagnostic markers of

prostate proliferation, and symptoms of the disease were assessed.

The primary endpoint of the study was the inhibition or reduction of

increased serum prostate-specific antigen (PSA) levels. The 6-mo

lycopene supplementation decreased PSA levels in men (P < 0.05),

whereas there was no change in the placebo group. The plasma

lycopene concentration increased in the group taking lycopene (P <

0.0001) but other plasma carotenoids were not affected. Whereas

progression of prostate enlargement occurred in the placebo group as

assessed by trans-rectal ultrasonography (P < 0.05) and digital

rectal examination (P < 0.01), the prostate did not enlarge in the

lycopene group. Symptoms of the disease, as assessed via the

International Prostate Symptom Score questionnaire, were improved in

both groups with a significantly greater effect in men taking

lycopene supplements. In conclusion, lycopene inhibited progression

of BPH.

PMID: 18156403

Rodney.

[Guest guest]

I saw on tv that americans eat 67# of tomatoes per capita.

That oughta be enough lycopene?

Regerds

[ ] Re: More support for lycopene's prostate benefits

Hi folks:

Here is the abstract of this paper:

Lycopene inhibits disease progression in patients with benign

prostate hyperplasia.

Schwarz S, Obermüller-Jevic UC, Hellmis E, Koch W, i G,

Biesalski HK.

University of Hohenheim, Institute of Biological Chemistry and

Nutrition, 70593 Stuttgart, Germany.

Lycopene is a promising nutritional component for chemoprevention of

prostate cancer (PCa). A possibly beneficial role of lycopene in

patients diagnosed with benign prostate hyperplasia (BPH), who are

at increased risk of developing PCa, has been suggested, although

clinical data are lacking. Therefore, this pilot study aimed to

investigate the effects of lycopene supplementation in elderly men

diagnosed with BPH. A total of 40 patients with histologically

proven BPH free of PCa were randomized to receive either lycopene at

a dose of 15 mg/d or placebo for 6 mo. The effects of the

intervention on carotenoid status, clinical diagnostic markers of

prostate proliferation, and symptoms of the disease were assessed.

The primary endpoint of the study was the inhibition or reduction of

increased serum prostate-specific antigen (PSA) levels. The 6-mo

lycopene supplementation decreased PSA levels in men (P < 0.05),

whereas there was no change in the placebo group. The plasma

lycopene concentration increased in the group taking lycopene (P <

0.0001) but other plasma carotenoids were not affected. Whereas

progression of prostate enlargement occurred in the placebo group as

assessed by trans-rectal ultrasonography (P < 0.05) and digital

rectal examination (P < 0.01), the prostate did not enlarge in the

lycopene group. Symptoms of the disease, as assessed via the

International Prostate Symptom Score questionnaire, were improved in

both groups with a significantly greater effect in men taking

lycopene supplements. In conclusion, lycopene inhibited progression

of BPH.

PMID: 18156403

Rodney.