The Secret To Long Life May Not Be In The Genes

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Hi All, The pdf of the paper is availed. http://www.sciencedaily.com:80/releases/2008/05/080505120818.htm Mellibovsky L, Bustamante M, Lluch P, Nogues X, Grinberg D, Balcells S, Diez- A. Bone mass of a 113-year-old man.J Gerontol A Biol Sci Med Sci. 2007 Jul;62(7):794-5.PMID: 17634329 Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms

of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. -- Al Pater, alpater@...

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