Re: I make sure i take my fish oil capsules

[Guest guest]

Hi folks:

Remember also that the average japanese is much slimmer than the average american ............... caloric restriction on a relative basis, which likely accounts for a large part of their reduced atherosclerosis. It would CERTAINLY explain much improved CVD risk biomarkers (as demonstrated in 'WUSTL', for example).

But the DHA & EPA no doubt greatly help reduce the erratic heart beat aspect of CVD.

Rodney.

>> "Our study suggests that the very low rates of coronary heart disease> among Japanese living in Japan may be due to their lifelong high> consumption of fish."> > "Japanese eat about 3 ounces (85 grams) of fish a day on average,> while Americans eat fish perhaps twice a week. Nutritional studies> show that intake of omega-3 fatty acids from fish averages 1.3 grams> per day in Japan, compared to 0.2 grams per day in the United States."> http://www.reuters.com/article/scienceNews/idUST10934120080728?feedType=RSS & feedName=scienceNews> > Abstract:> > Marine-Derived n-3 Fatty Acids and Atherosclerosis in Japanese,> Japanese-American, and White Men> > Results: Japanese men had the lowest levels of atherosclerosis,> whereas whites and Japanese Americans had similar levels. Japanese had> 2-fold higher levels of marine-derived n-3 fatty acids than whites and> Japanese Americans in the U.S. Japanese had significant and> nonsignificant inverse associations of marine-derived n-3 fatty acids> with IMT and CAC prevalence, respectively. The significant inverse> association with IMT remained after adjusting for traditional> cardiovascular risk factors. Neither whites nor Japanese Americans had> such associations. Significant differences between Japanese and whites> in multivariable-adjusted IMT (mean difference 39 µm, 95% confidence> interval [CI]: 21 to 57µm, p < 0.001) and CAC prevalence (mean> difference 10.7%, 95% CI: 2.9% to 18.4%, p = 0.007) became> nonsignificant after we adjusted further for marine-derived n-3 fatty> acids (22 µm, 95% CI: –1 to 46 µm, p = 0.065 and 5.0%, 95% CI: –5.3%> to 15.4%, p = 0.341, respectively).> > Conclusions: Very high levels of marine-derived n-3 fatty acids have> antiatherogenic properties that are independent of traditional> cardiovascular risk factors and may contribute to lower the burden of> atherosclerosis in Japanese, a lower burden that is unlikely the> result of genetic factors.> http://content.onlinejacc.org/cgi/content/short/52/6/417>

[Guest guest]

The Japanese men in this study (

http://www.theheart.org/article/884341.do )have a " Mean carotid IMT of

614(µm) " .

How does this compare to the WUSTL subjects?

>

> " Our study suggests that the very low rates of coronary heart disease

> among Japanese living in Japan may be due to their lifelong high

> consumption of fish. "

>

> " Japanese eat about 3 ounces (85 grams) of fish a day on average,

> while Americans eat fish perhaps twice a week. Nutritional studies

> show that intake of omega-3 fatty acids from fish averages 1.3 grams

> per day in Japan, compared to 0.2 grams per day in the United States. "

>

http://www.reuters.com/article/scienceNews/idUST10934120080728?feedType=RSS & feed\

Name=scienceNews

>

> Abstract:

>

> Marine-Derived n-3 Fatty Acids and Atherosclerosis in Japanese,

> Japanese-American, and White Men

>

> Results: Japanese men had the lowest levels of atherosclerosis,

> whereas whites and Japanese Americans had similar levels. Japanese had

> 2-fold higher levels of marine-derived n-3 fatty acids than whites and

> Japanese Americans in the U.S. Japanese had significant and

> nonsignificant inverse associations of marine-derived n-3 fatty acids

> with IMT and CAC prevalence, respectively. The significant inverse

> association with IMT remained after adjusting for traditional

> cardiovascular risk factors. Neither whites nor Japanese Americans had

> such associations. Significant differences between Japanese and whites

> in multivariable-adjusted IMT (mean difference 39 µm, 95% confidence

> interval [CI]: 21 to 57µm, p < 0.001) and CAC prevalence (mean

> difference 10.7%, 95% CI: 2.9% to 18.4%, p = 0.007) became

> nonsignificant after we adjusted further for marine-derived n-3 fatty

> acids (22 µm, 95% CI: –1 to 46 µm, p = 0.065 and 5.0%, 95% CI: –5.3%

> to 15.4%, p = 0.341, respectively).

>

> Conclusions: Very high levels of marine-derived n-3 fatty acids have

> antiatherogenic properties that are independent of traditional

> cardiovascular risk factors and may contribute to lower the burden of

> atherosclerosis in Japanese, a lower burden that is unlikely the

> result of genetic factors.

> http://content.onlinejacc.org/cgi/content/short/52/6/417

>

[Guest guest]

Hi Bill:

Interesting paper. Thank you.

IIRC the CRON WUSTL subjects' carotid IMT was 0.5 mm (better than the japanese in Japan) and the control group was 0.8 mm (apparently worse than the american subjects in the paper you posted.)

However the WUSTL numbers, evidently, are rounded.

Rodney.

> >> > "Our study suggests that the very low rates of coronary heart disease> > among Japanese living in Japan may be due to their lifelong high> > consumption of fish."> > > > "Japanese eat about 3 ounces (85 grams) of fish a day on average,> > while Americans eat fish perhaps twice a week. Nutritional studies> > show that intake of omega-3 fatty acids from fish averages 1.3 grams> > per day in Japan, compared to 0.2 grams per day in the United States."> >> http://www.reuters.com/article/scienceNews/idUST10934120080728?feedType=RSS & feedName=scienceNews> > > > Abstract:> > > > Marine-Derived n-3 Fatty Acids and Atherosclerosis in Japanese,> > Japanese-American, and White Men> > > > Results: Japanese men had the lowest levels of atherosclerosis,> > whereas whites and Japanese Americans had similar levels. Japanese had> > 2-fold higher levels of marine-derived n-3 fatty acids than whites and> > Japanese Americans in the U.S. Japanese had significant and> > nonsignificant inverse associations of marine-derived n-3 fatty acids> > with IMT and CAC prevalence, respectively. The significant inverse> > association with IMT remained after adjusting for traditional> > cardiovascular risk factors. Neither whites nor Japanese Americans had> > such associations. Significant differences between Japanese and whites> > in multivariable-adjusted IMT (mean difference 39 µm, 95% confidence> > interval [CI]: 21 to 57µm, p < 0.001) and CAC prevalence (mean> > difference 10.7%, 95% CI: 2.9% to 18.4%, p = 0.007) became> > nonsignificant after we adjusted further for marine-derived n-3 fatty> > acids (22 µm, 95% CI: –1 to 46 µm, p = 0.065 and 5.0%, 95% CI: –5.3%> > to 15.4%, p = 0.341, respectively).> > > > Conclusions: Very high levels of marine-derived n-3 fatty acids have> > antiatherogenic properties that are independent of traditional> > cardiovascular risk factors and may contribute to lower the burden of> > atherosclerosis in Japanese, a lower burden that is unlikely the> > result of genetic factors.> > http://content.onlinejacc.org/cgi/content/short/52/6/417> >>