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Re: Exercise and body mass index vs female heart disease

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Hi folks:

For what it is worth the following table shows what I believe may be the best way, given the data in the paper Al posted, to assess the benefit of exercise with CRON. (I hope this formats legibly!):

CRON 'Normal' Overweight Obese

-------- ----- -------- ----------- -------

(CVD Risk)

Inactive ????? 1·08 1.88 2.53

Active ????? 1·00 1·54 1·87

-------- ------ -------- ----------- -------

Benefit* ? 7% 18% 26%

====== ===== ====== ========= ======

*Benefit is calculated as: 1 - active/inactive x 100

The cardiovascular benefit of exercise for the obese women in this study was a 26% reduction in risk. For overweight women exercise reduced CVD incidence by 18%. For those with a BMI below 25 the risk reduction attributable to exercise was 7%.

They did not determine the risk for people on CRON with, for a number, a BMI of 18 to 22. Had they done so we can presumably be confident the benefit would have been appreciably less than the 7% benefit of all those with a BMI below 25. This is because we know from looking around us, and from the minuscule proportion of the population doing CRON, that the vast majority of the members of their 'normal weight' sample will have had a BMI only marginally below 25.

Indeed, based on these data it is not out of the question that the benefit of appreciable amounts of exercise in a CRON group might be negative. First, the benefit clearly declines fairly quickly with BMI as shown in the above table. Second, logically we know that extra exercise beyond a certain very necessary threshold amount will entail the processing of additional calories along with the creation of more oxidation products.

Of course, this paper does not *prove* the benefits of exercise are negative when done in combination with CRON. But the data are suggestive. These data certainly do appear to show that if the benefit is positive it is sizeably less than 7%. In other words, pretty much negligible.

Rodney.

>> Hi All,> > Exercise and body mass index interactions in women's heart disease risk seem to be examined. The below paper is free full-text.> > > In This Issue of Archives of Internal Medicine> Arch Intern Med. 2008;168(8):790. > The Joint Effects of Physical Activity and Body Mass Index on Coronary Heart Disease Risk in Women > > Physical activity and body mass index (BMI) independently alter the risk of coronary heart disease (CHD); however, their combined effect on CHD is not established. Weinstein et al prospectively studied the combined association of physical activity and BMI on incident CHD in a cohort of 38 987 healthy women in the Women's Health Study. The risk of CHD associated with elevated BMI was considerably reduced by increasing physical activity levels. Increasing levels of walking also resulted in significant reductions in CHD risk for overweight and obese individuals. However, the risk was not completely eliminated by physical activity, reinforcing the importance of being lean and physically active.> > > The Joint Effects of Physical Activity and Body Mass Index on Coronary Heart Disease Risk in Women> Amy R. Weinstein; D. Sesso; I-Min Lee; M. Rexrode; R. Cook; JoAnn E. Manson; E. Buring; J. Gaziano> Arch Intern Med. 2008;168(8):884-90.> > http://archinte.ama-assn.org/cgi/content/full/168/8/884> http://tinyurl.com/58kwuh> > -- Al Pater, alpater@...> > > ---------------------------------> Be a better friend, newshound, and know-it-all with Mobile. Try it now.>

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Of course your analysis includes only CVD risk and not QOL concerns

and retained functional strength for CRON into advanced aging.

Personally, I want to get strong, stay strong with sufficient

functional strength and flexibility in muscle and bone to move my body

with fluidity through space @100+. And the ability to manipulate

objects with relative safety and aplomb.

As been shown here before reasonable exercise doesn't burn that many

additional calories anyway, and therefore will not require that many

additional calories. Strength training moving quickly between the

exercises with little rest can provide aerobic fitness as well as

strength development and retention.

> >

> > Hi All,

> >

> > Exercise and body mass index interactions in women's heart disease

> risk seem to be examined. The below paper is free full-text.

> >

> >

> > In This Issue of Archives of Internal Medicine

> > Arch Intern Med. 2008;168(8):790.

> > The Joint Effects of Physical Activity and Body Mass Index on Coronary

> Heart Disease Risk in Women

> >

> > Physical activity and body mass index (BMI) independently alter the

> risk of coronary heart disease (CHD); however, their combined effect on

> CHD is not established. Weinstein et al prospectively studied the

> combined association of physical activity and BMI on incident CHD in a

> cohort of 38 987 healthy women in the Women's Health Study. The risk of

> CHD associated with elevated BMI was considerably reduced by increasing

> physical activity levels. Increasing levels of walking also resulted in

> significant reductions in CHD risk for overweight and obese individuals.

> However, the risk was not completely eliminated by physical activity,

> reinforcing the importance of being lean and physically active.

> >

> >

> > The Joint Effects of Physical Activity and Body Mass Index on Coronary

> Heart Disease Risk in Women

> > Amy R. Weinstein; D. Sesso; I-Min Lee; M. Rexrode;

> R. Cook; JoAnn E. Manson; E. Buring; J. Gaziano

> > Arch Intern Med. 2008;168(8):884-90.

> >

> > http://archinte.ama-assn.org/cgi/content/full/168/8/884

> > http://tinyurl.com/58kwuh

> >

> > -- Al Pater, alpater@

> >

> >

> > ---------------------------------

> > Be a better friend, newshound, and know-it-all with Mobile. Try

> it now.

> >

>

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