Guest guest Posted July 3, 2008 Report Share Posted July 3, 2008 Resveratrol has plus and zeros. It counters aging conditions, but not aging. I am pleased to not have invested $ in resveratrol. The below paper is pdf-availed. http://www.sciencedaily.com:80/releases/2008/07/080703120402.htmhttp://tinyurl.com/6oq4jj http://www.cbc.ca/health/story/2008/07/03/wine-aging.html http://health.usnews.com:80/articles/health/healthday/2008/07/03/compound-in-red-wine-fights-ravages-of-age.html http://tinyurl.com/5m75o3 http://www.sciencenews.org:80/view/generic/id/33832/title/Fountain_of_Youth,_with_caveats http://tinyurl.com/6qwd7e http://ukpress.google.com/article/ALeqM5gqiZpHm3v9fsdam_0H6-iyhGW0Yg http://tinyurl.com/5z5r29 Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span J. Pearson, ph A. Baur, Kaitlyn N. , Leonid Peshkin, L. Price, Nazar Labinskyy, R. Swindell, a Kamara, Robin K. Minor, , Hamish A. son, Yongqing Zhang, R. Dunn, Kumar Sharma, Pleshko, A. Woollett, Csiszar, Yuji Ikeno, Le Couteur, J. Elliott, G. Becker, Placido Navas, K. Ingram, Norman S. Wolf, Zoltan Ungvari, A. Sinclair, and de Cabo Summary A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related diseases in laboratory animals is greatly sought after. We and others have shown that resveratrol mimics effects of DR in lower organisms. In mice, we find that resveratrol induces gene expression patterns in multiple tissues that parallel those induced by DR and every-other-day feeding. Moreover, resveratrol-fed elderly mice show a marked reduction in signs of aging, including reduced albuminuria, decreased inflammation, and apoptosis in the vascular endothelium, increased aortic elasticity, greater motor coordination, reduced cataract formation, and preserved bone mineral density. However, mice fed a standard diet did not live longer when treated with resveratrol beginning at 12 months of age. Our findings indicate that resveratrol treatment has a range of beneficial effects in mice but does not increase the longevity of ad libitum-fed animals when started midlife. .... Acknowledgments A. Sinclair declares he is a consultant to Sirtris, a GSK sirtuin company, and a board member/shareholder of Genocea Biosciences, a vaccine company. J. Elliott declares he is a full-time employee and shareholder of GSK/Sirtris. ... -- Al Pater, alpater@... Quote Link to comment Share on other sites More sharing options...
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