Metabolic Rate, CR in Primates vs Rodents

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In regard to the current discussion of metabolic rate in rodents,

please note that primates and humans consistently show reduced EE as

opposed to mixed results in rodents. [1], [2], [3]

For a discussion of these conflicting results see:

Calorie restriction and aging: review of the literature and

implications for studies in humans1 [4]

1.Blanc S, Schoeller D, Kemnitz J, et al. Energy expenditure of

rhesus monkeys subjected to 11 years of dietary restriction. J Clin

Endocrinol Metab 2003;88:16–23.[Abstract/Free Full Text]

2.Ramsey JJ, Roecker EB, Weindruch R, Kemnitz JW. Energy expenditure

of adult male rhesus monkeys during the first 30 mo of dietary

restriction. Am J Physiol 1997;272:E901–7.

3. Girard N, Ferland G, Boulanger L, Gaudreau P. Long-term calorie

restriction protects rat pituitary growth hormone-releasing hormone

binding sites from age-related alterations. Neuroendocrinology

1998;68:21–9.[Medline]

4. http://tinyurl.com/62gkc6