Biomarkers ...Re: Need Advice on Stabilizing Weight (Optimum BMI for longevity)

[Guest guest]

Jeff,

The interesting thing (to me) is that our experience practicing

CRON, your experience as a naturally thin person and mine as the proud

owner of the " thifty gene " , makes it appear that humans respond to

CRON just as mice do. I understand that much more data would be

needed to scientifically establish the relationship, but it is

interesting.

Thin mice get " razor " thin on CRON. Ob/ob mice get to a normal

weight or even stay somewhat obese with the same level of

restriction. Both types are more healthy and live far longer than

normally fed mice.

If naturally thin and naturally fat humans repond to CRON in

the same way as naturally fat and thin mice, then doesn't that

strengthen the argument that humans, like mice, are also likely to see

the same sort of life extension and resistance to chronic disease?

Would be great to see some research in this area. I haven't

seen any, has anyone else?

> >

>

> It is my opinion that if someone is already lean, unless they are

> engaging in an enormous amount of exercise, then they are already

> practicing CR to some degree or more. How else could they be

lean?

> Therefore, I think their focus should be on the ON part

>

> Regards

> Jeff

>