Saturated fat risks to heart

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Hi All, The below paper is pdf-availed, and appears to validate low saturated fat diets that may tend to represent the diet of our less "civilized" counterparts. Rodríguez-Morán M, Guerrero-Romero F, Brito-Zurita O, Rascón-Pacheco RA, Pérez-Fuentes R, Sánchez-Guillén MC, González-Ortiz M, Martínez-Abundis E, Simental-Mendía LE, Madero A, Revilla-Monsalve C, -Martínez SE, Islas-Andrade S, Cruz M, Wacher N, Sánchez-Corona J.Cardiovascular Risk Factors and Acculturation in Yaquis and Tepehuanos Indians from Mexico.Arch Med Res. 2008 Apr;39(3):352-357.PMID: 18279710BackgroundCardiovascular (CV) risk factors are influenced by behavioral, cultural, and social factors, suggesting that acculturation plays a significant role in the emergency and growth of chronic disease. The objective of this study was to determine the relation between CV risk factors and the main components

of acculturation, in Yaquis and Tepehuanos Indians from Mexico.MethodsThis was a cross-sectional population-based study in Yaquis and Tepehuanos communities from the Yaqui Valley in Sonora and the Sierra Madre Occidental Mountains in Durango, in northwest Mexico. Acculturation status is different in both ethnic groups, with Tepehuanos living in small and remote communities retaining their traditional lifestyle and Yaquis living in well-communicated communities that have assumed Westernized lifestyles.ResultsA total of 278 indigenous (120 Tepehuanos and 158 Yaquis) were randomly enrolled. Prevalence of obesity (48.1 and 6.7%, p <0.001), diabetes (18.3 and 0.83%, p <0.001), hypertriglyceridemia (43.0 and 15.0%, p <0.001), alcohol consumption (46.8 and 26.6%, p >0.001), and smoking (29.7 and 15.0%, p = 0.006) were significantly higher in Yaquis Indians. High blood pressure (6.3 and 3.3%, p = 0.40) and low HDL-cholesterol (42.4 and

34.2%, p = 0.22) were similar between Yaquis and Tepehuanos. Multivariate regression analysis adjusted by sex and age showed a significant association between calorie intake from saturated fat, but not other nutrients of customary diet, with hyperglycemia (OR 7.4, 95% CI 2.6-20.1), hypertriglyceridemia (OR 3.1, 95% CI 1.5-6.3), and obesity (OR 3.4, 95% CI 1.6-10.1).ConclusionsAmong the components of acculturation, intake of saturated fat is the most strongly associated with the development of CV risk factors.Key Words: Acculturation; Aboriginal health; Cardiovascular risk; Mexico; Yaquis; Tepehuanos Table 1. Anthropometric and laboratory characteristics of Yaquis and Tepehuanos Indians from Northwest Mexico (March 2006 to February 2007, n = 278).============================================= Women---Men Yaquis Tepehuanos---Yaquis

Tepehuanos n = 119 n = 46 p---n = 39 n = 74 p=============================================Age (years) 37.5±10.1 33.9±8.6 0.03 44.4±11.3 30.5±10.1 <0.001Body mass index (kg/m2) 30.2±5.6 24.2±5.1 <0.001 29.4±3.8) 22.1±3.0 <0.001Waist circumference (cm) 101.2±11.6 81.2±13.5 <0.001 103.8±8.0 79.1±8.1 <0.001Total body fat (%) 38.1±6.6 25.8±8.2 <0.001 28.1±8.2 15.2±6.8 <0.001Systolic blood pressure (mmHg) 109.0±15.1 108.4±14.1 0.08 117.3±15.2 114.4±94.0 0.33Diastolic blood pressure (mmHg) 72.5±10.3 67.5±10.3 0.006 77.7±9.3 68.7±11.6 0.001Fasting glucose (mmol/L) 5.7±2.0 4.8±0.6 <0.001 6.2±3.3 4.5±0.4 <0.001Postload glucose (mmol/L) 9.3±4.2 -* - 9.6±4.1 -* -Fasting insulin (mmol/L) 65.4±60.0 46.8±33.0 0.01 43.2±21.6 26.4±16.8 0.001Total cholesterol (mmol/L) 4.9±0.9 4.3±0.9 0.001 5.3±0.9 4.1±0.8 <0.001HDL-cholesterol (mmol/L) 1.0±0.2 1.0±0.4 0.86

0.9±0.2 0.9±0.3 0.45Triglycerides (mmol/L) 1.8±1.1 1.5±1.2 0.13 2.3±1.9 1.2±0.8 0.003============================================= Values are expressed as mean±SD. * Because of their traditional religion and cultural background, Tepehuanos Indians did not drink the glucose load; therefore, data are missing. alpater@...

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