Guest guest Posted May 13, 2009 Report Share Posted May 13, 2009 There are several levels of vitamin D status that are worth considering. The traditional one is that required to prevent rickets. The next is the level that has been shown to be correlated with good health. There is yet another level that I will call therapeutic. Rickets prevention is well understood, and all we need to do to prevent it is to apply well established knowledge. The current explosion in vitamin D interest is about the level of vitamin D required for good health. A considerable amount of disease occurs when vitamin D status is low, such as in winter and in northern latitudes. The winter flu season could be eliminated by adequate supplementation, probably about 2000 IU per day for most people. Therapeutic use of vitamin D is a different animal than simply maintaining average health. When blood levels of 150-200 ng/ml (and above) are achieved, the health benefits include the reversal of many health challenges. Things like people who suffer from MS getting out of their wheelchairs and walking. Lung cancer being cured. Resistance to viruses multiplied by 5 times. There are literally dozens of different conditions that have benefited from such high dose therapy. But if you require double blind crossover studies of thousands of people before you believe something, I guess you're not going to believe these reports. I've had the good fortune of council from Dr. Joe Prendergast. He has decades of experience using vitamin D, and has observed many of these recoveries firsthand. His track record includes curing his own case of major vascular calcification. Over a period of 10 years, he rejuvenated his arteries from those of an 80-year old to their current condition of a teenager. One third of his type-1 diabetes patients are off insulin completely. The local hospital called him up to see if he was still in practice. It seems he hadn't admitted anyone there in the past 10 years. Not bad for an endocrinology practice with 80% diabetics. So what are the miracle treatments that Dr. Prendergast uses? Arginine (5 gm), Citrulline (1 gm), Benfotiamine, and vitamin D3 (150-200 ng/ml blood level). The diabetics get Byetta to rejuvenate their pancreas. Vascular problems may get an angiotensin blocker (valsartan) as a temporary (not lifetime) treatment. He has a white paper on arginine at http://www.endocrinemetabolic.com/about/press/larginine.pdf . I don't know if he recommends it, but I also use 90 mcg of MK-7, a subcomponent of vitamin K2 that improves calcium distribution. Just what Dr. Prendergast recommends for me in the future is, as the word says, the future. My interest in using 50,000 IU of D3 per day is that it is my current approximation of the optimum quantity. Note that I have regular blood tests for vitamin D and calcium. Since absorption varies between people, the quantity that I use may be considerably more or less than what other people could use. Note also that the combination of high D and calcium supplementation is a prescription for problems. If you can't get rid of the idea of calcium supplementation, don't even think about such a high dose of D3. The high D invokes all the calcium absorption that is appropriate. So what do I expect from high D3 therapy? The redistribution of calcium from inappropriate sites (arteries, bone spurs, kidney stones, etc.) to beneficial sites like the bone matrix. Improved immune function is a major effect of having high vitamin D status. It has even been suggested as the universal vaccine, in that it doesn't have to be customized for each virus. Two excellent websites for scientific data on vitamin D are: http://vitamindcouncil.org (Dr. Cannell) http://sunarc.org (Dr. Grant) Side note: Dr. Grant probably started the current rage of interest in vitamin D with his carefully presented observations of the medical literature. Since he scrupulously adheres to using the highest quality scientific data, he has little to say about my 50,000 IU usage. He is aware of Dr. Prendergast, and, more personally, me. Hi Bill, the canary's still alive! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2009 Report Share Posted May 13, 2009 Rob: Thanks for your post. It’s my understanding that the proper amount of Vit D is still debatable. And yes we need evidence that “people with MS are getting out of their wheelchairs and walking” and similar phrases you are making below. Obviously you’re convinced that this is the magic bullet but some of us need actual proof. I would love to see the scientific backing for this as well as cures for lung cancer or other such claims. Sounds too good to be true and usually it is. Evidence via peer-reviewed studies preferably with many subjects (a few thousand for example) is what is respected here. A doctor’s statement that he has seen many “cures” doesn’t qualify. That’s anecdotal only. You may all remember just a few short years ago, many doctors were jumping on the bandwagon advocating hormones for post-menopausal women which supposedly cured just about everything under the sun and were the “fountain of youth” . I was one of the guinea pigs, imbibing for 10 years. It’s a wonder I didn’t get cancer. Such nonsense has gone on throughout medical history. I am old enough to remember Dr Linus ing coming out with his book that Vit C cured just about everything under the sun, including cancer. Does that claim sound familiar? Dr ing was no slouch either; a Nobel Prize winning scientist. Luckily, unlike ingesting hormones, Vit C is fairly harmless because as it happens, people all around the world started popping Vit C like it was going out of style. No doubt many Vitamin company execs got very very rich. So I’m a bit skeptical. That said, I’ve upped my daily dose (in all but the summer months) of Vit D to 2000IU. But I don’t expect miracles. From: Rob_Larson <Rob_Larson@...> Reply-< > Date: Wed, 13 May 2009 04:50:06 -0000 < > Subject: [ ] Re: How much Vit D? (again) There are several levels of vitamin D status that are worth considering. The traditional one is that required to prevent rickets. The next is the level that has been shown to be correlated with good health. There is yet another level that I will call therapeutic. Rickets prevention is well understood, and all we need to do to prevent it is to apply well established knowledge. The current explosion in vitamin D interest is about the level of vitamin D required for good health. A considerable amount of disease occurs when vitamin D status is low, such as in winter and in northern latitudes. The winter flu season could be eliminated by adequate supplementation, probably about 2000 IU per day for most people. Therapeutic use of vitamin D is a different animal than simply maintaining average health. When blood levels of 150-200 ng/ml (and above) are achieved, the health benefits include the reversal of many health challenges. Things like people who suffer from MS getting out of their wheelchairs and walking. Lung cancer being cured. Resistance to viruses multiplied by 5 times. There are literally dozens of different conditions that have benefited from such high dose therapy. But if you require double blind crossover studies of thousands of people before you believe something, I guess you're not going to believe these reports. I've had the good fortune of council from Dr. Joe Prendergast. He has decades of experience using vitamin D, and has observed many of these recoveries firsthand. His track record includes curing his own case of major vascular calcification. Over a period of 10 years, he rejuvenated his arteries from those of an 80-year old to their current condition of a teenager. One third of his type-1 diabetes patients are off insulin completely. The local hospital called him up to see if he was still in practice. It seems he hadn't admitted anyone there in the past 10 years. Not bad for an endocrinology practice with 80% diabetics. So what are the miracle treatments that Dr. Prendergast uses? Arginine (5 gm), Citrulline (1 gm), Benfotiamine, and vitamin D3 (150-200 ng/ml blood level). The diabetics get Byetta to rejuvenate their pancreas. Vascular problems may get an angiotensin blocker (valsartan) as a temporary (not lifetime) treatment. He has a white paper on arginine at http://www.endocrinemetabolic.com/about/press/larginine.pdf . I don't know if he recommends it, but I also use 90 mcg of MK-7, a subcomponent of vitamin K2 that improves calcium distribution. Just what Dr. Prendergast recommends for me in the future is, as the word says, the future. My interest in using 50,000 IU of D3 per day is that it is my current approximation of the optimum quantity. Note that I have regular blood tests for vitamin D and calcium. Since absorption varies between people, the quantity that I use may be considerably more or less than what other people could use. Note also that the combination of high D and calcium supplementation is a prescription for problems. If you can't get rid of the idea of calcium supplementation, don't even think about such a high dose of D3. The high D invokes all the calcium absorption that is appropriate. So what do I expect from high D3 therapy? The redistribution of calcium from inappropriate sites (arteries, bone spurs, kidney stones, etc.) to beneficial sites like the bone matrix. Improved immune function is a major effect of having high vitamin D status. It has even been suggested as the universal vaccine, in that it doesn't have to be customized for each virus. Two excellent websites for scientific data on vitamin D are: http://vitamindcouncil.org (Dr. Cannell) http://sunarc.org (Dr. Grant) Side note: Dr. Grant probably started the current rage of interest in vitamin D with his carefully presented observations of the medical literature. Since he scrupulously adheres to using the highest quality scientific data, he has little to say about my 50,000 IU usage. He is aware of Dr. Prendergast, and, more personally, me. Hi Bill, the canary's still alive! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2009 Report Share Posted May 13, 2009 I've been taking 5000 IU/day for two years or more, so I'll report back what my blood levels are when I next have blood drawn. Maco At 07:24 AM 05/13/2009, Francesca wrote: Rob: Thanks for your post. It’s my understanding that the proper amount of Vit D is still debatable. And yes we need evidence that “people with MS are getting out of their wheelchairs and walking” and similar phrases you are making below. Obviously you’re convinced that this is the magic bullet but some of us need actual proof. I would love to see the scientific backing for this as well as cures for lung cancer or other such claims. Sounds too good to be true and usually it is. Evidence via peer-reviewed studies preferably with many subjects (a few thousand for example) is what is respected here. A doctor’s statement that he has seen many “cures” doesn’t qualify. That’s anecdotal only. You may all remember just a few short years ago, many doctors were jumping on the bandwagon advocating hormones for post-menopausal women which supposedly cured just about everything under the sun and were the “fountain of youth” . I was one of the guinea pigs, imbibing for 10 years. It’s a wonder I didn’t get cancer. Such nonsense has gone on throughout medical history. I am old enough to remember Dr Linus ing coming out with his book that Vit C cured just about everything under the sun, including cancer. Does that claim sound familiar? Dr ing was no slouch either; a Nobel Prize winning scientist. Luckily, unlike ingesting hormones, Vit C is fairly harmless because as it happens, people all around the world started popping Vit C like it was going out of style. No doubt many Vitamin company execs got very very rich. So I’m a bit skeptical. That said, I’ve upped my daily dose (in all but the summer months) of Vit D to 2000IU. But I don’t expect miracles. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2009 Report Share Posted May 13, 2009 I have to take 2000mg of D3 a day just to keep my blood levels in the normal range. My 8 year old son tested low, so his nutritionist recommended at least 1000mg a day for him. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2009 Report Share Posted May 15, 2009 Hi : I am not trying to extract information you might consider confidential! But it would be really helpful to the group to know what, in numerical terms, 2000 IU per day has done to your serum 25(OH)D ............ since the (quite new) acceptable range (at least the one I am familiar with here) is pretty wide ......... like 75 to 250 nmol/L, (or 30 to 100 ng/ml). In other words, did 2000 IU per day raise your serum level to 80, say? Or 220, perhaps? Big difference. After TWO MONTHS I still do not have my results back from two separate blood samples submitted. It looks like I *will* eventually be getting them and will post them as soon as I have them. I have been taking 3500 IU of D3 for many months now. I called the lab doing the actual analysis, and found someone who did seem to be knowledgeable. She told me that they are way behind in testing the samples. She also said that the DiaSorin test misses some of the 25(OH)D present in the samples, so the test they are using which, it is claimed, is more 'accurate' than DiaSorin, comes out with somewhat higher numbers. They are NOT using a Quest test! Stay tuned. Rodney. > > I have to take 2000mg of D3 a day just to keep my blood levels in the normal range. My 8 year old son tested low, so his nutritionist recommended at least 1000mg a day for him. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2009 Report Share Posted May 15, 2009 Hi, Rodney. I actually don't know what my number was before I started taking the D3, but after deciding that my years of hiding from the sun and age of 51 put me at risk for low D levels, I took the supplement for several months and then asked my doctor to check vitamin levels at my annual appointment. My lab test came back as 38 ng/ml. So I believe I need the supplemental D just to stay in the normal range. > > > > I have to take 2000mg of D3 a day just to keep my blood levels in the > normal range. My 8 year old son tested low, so his nutritionist > recommended at least 1000mg a day for him. > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2009 Report Share Posted May 15, 2009 Thanks . That is another one-mouse observation - 2000 IU/day results in a 38 ng/ml blood level. That is very similar to the number I had after taking 50,000 IU/week of D2 for twelve weeks (prescribed). At the outset - I had been taking small amounts weekly - my 25(OH)D was 71 nmol/L (acceptable range 75 to 250). When the prescription ran out it was up to 92. Then I took no supplements during the summer but got 10 to 15 minutes swimming trunks sun exposure front and 10 to 15 minutes back three times a week, and my next test remained in the 90s. So I have concluded that a modest amount of sun exposure doesn't do a lot for my 25(OH)D. For the past eight months I have been ignoring the sun - there isn't any worth talking about here anyway - and taking about 3500 IU daily. It remains to be seen how much effect this has had. Rodney. > > > > > > I have to take 2000mg of D3 a day just to keep my blood levels in the > > normal range. My 8 year old son tested low, so his nutritionist > > recommended at least 1000mg a day for him. > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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