REAACH Alert:MAYO Clinic/Thimerosal #4

August 22, 2006

Mayo Clinic identifies top ten contact dermatitis allergens; THIMEROSAL is #4

the connection by Mayo Clinic of thimerosal to inflammatory response lays groundwork for what we already know.:

other more insidious inflammatory responses of the body to thimerosal. REAACH hopes that the scientists in out community

will atempt tO conNEct with these scientists in offering research that makes the leap. Suzanne Messina REAACH

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Contact Dermatitis Allergens

From Judy Tidwell,Your Guide to Allergies.FREE Newsletter. Sign Up Now!

Top Ten Contact Dermatitis Allergens Identified

Almost anything that comes in contact with the skin can cause allergic contact dermatitis. It occurs when the body's immune system senses a known allergen and reacts to expel it. This skin reaction or inflammation usually manifests with swollen, reddened and itchy skin.

Research conducted by the Mayo Clinic identified the most common causes of allergic contact dermatitis after examining contact dermatitis testing results from 3,854 patients over a five-year period between Jan. 1, 2001 and Dec. 31, 2005. The study also confirmed the standard panel of patch testing performed for contact dermatitis patients is useful in indentifying common contact allergens.

According to a news release, the top ten contact dermatitis allergens indentified in this study were:

Nickel (nickel sulfate hexahydrate)Nickel is found in many products.

It can be found in jewelry, buckles, zippers, snaps, buttons, hair-pins, and metal clips. Be aware that any metal product may contain nickel.

Gold (gold sodium thiosulfate)Gold is a precious metal often found in jewelry and also used in the denistry field.

Balsam of Peru (myroxylon pereirae)Balsam of Peru originates from a tree resin and is used in fragrances, skin care products, flavoring in foods, health and beauty aids, and medicinal creams and oitments. Not only is Balsam of Peru aromatic, but it delays evaporation and also acts as a mild antibacterial, antifungal and antiparasitic.

ThimerosalThimerosal is a mercury compound used in local antiseptics and in vaccines. It is used as a perservative in many items such as cosmetics, pharmaceutical products, vaccines, and skin prict test antigens.

Neomycin sulfateNeomycin sulfate is an antibacterial used widely in first-aid or antibiotic creams and ointments, eye and ear preparations. It is also used in combination with other antibacterials corticosteroids. These combination preparations treat a variety of skin, eye, and ear infections.

Fragrance mixFragrance mix is a sceening agent that is used to pinpoint the cause of a large percentage of skin allergies. This fragrance mix contains eight known skin sensitizers which are found in foods, cosmetic products, insecticides, antiseptics, soaps, perfumes, and dental products.

FormaldehydeFormaldehyde is a chemical widely used in many building materials and household products. It is a preservative with multiple uses. Some of the sources of formaldehyde include paper products, paints, medications, household cleaners, cosmetic products and fabric finishes. It is impossible to list all the sources of formaldehyde exposure.

Cobalt chlorideCobalt chloride is a metal that is found in medical products such as Vitamin B12 preparations, metal prostheses and dental plates. It is also present in many metal plated objects such as snaps, button, or tools. Because cobalt pigment produces light brown shades of hair, it is used in hair dye. It can also be found in antiperspirant preparations. Cobalt blue pigment can be found in porcelain, glass, pottery, ceramics, enamels, and blue or green water colour paints and crayons.

BacitracinBacitracin is a topical antibiotic that is used for a variety of localized skin and eye infections.

Quaternium 15Quaternium 15 is a formaldehyde-releasing preservative found in cosmetics products such as eye make-up, foundations, powders. It can also be found in shampoos, soaps, self-tanners, baby powders, nail polish and sunscreen. Commercial and industrial products such as adhesives, floor waxes or polishes, latex paints, paperboard, laundry starch, and water based inks also may contain Quaternium.

Can Cause Minor Annoyance to More Severe HandicapsContact dermatitis is common among all age groups and can cause minor annoyance to more severe handicaps, according to Mark , M.D., Mayo Clinic dermatologist and lead study researcher. "Patients with contact dermatitis can get a very itchy rash from head to toe, or in a confined area," he says in a Mayo Clinic news release. "If it's on the hands and feet it can be disabling, and patients at times can't do their jobs."

Dr. adds that even though allergen avoidance is the chief treatment for allergic contact dermatitis, there are times when corticosteroid creams are needed to treat the rashes. However, 3 percent of the patients with contact dermatitis are also allergic to topical steriods that could be used to treat their rashes and alleviate their symptoms.

Source: Mayo Clinic

References:

Gold AllergyBalsam of Peru AllergyThiomersal AllergyNeomycin AllergyFragrance Mix AllergyFormaldehyde AllergyCobalt AllergyBacitracinQuaternium-15 Allergy

Updated: August 22, 2006

Judy Tidwell, About.com's Guide to Allergies since 1998, is a writer in South Carolina. An allergy sufferer herself, Judy hopes her writing can help others to better understand and cope with their condition.

Important disclaimer information about this About site.

Contact Dermatitis

Contact DermatitisContact Dermatitis: Caused by Some MetalsFacial Contact Dermatitis

Contact Dermatitis Causes

Fragrance SenstivityThe Itch That Won't QuitAllergic to Nickel

Allergic Contact Dermatitis

Allergic Vs. Irritant Contact DermatitisAllergic Contact Dermatis OverviewAllergic Contact Dermatitis Distribution

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