Regarding high protein diets

[Guest guest]

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently

studying the link between Alzheimer's and diabetes. Ironically partially due to

depression which compounded some bad eating choices I developed reactive

hypoglycemia. I have significant interest in CRON for health reasons (and

partially professional)but am a bit weary about having to do so much work to

measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if

anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of

advanced glycolation end products). I would love to try it out but am a bit

scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high

protein diets but I wanted to say that there are risk factors associated with

these type of diets (For example Molecular Neurodegenration published an article

linking this type of diet to Alzheimer's)

Thanks HM

[Guest guest]

I’d be careful about an all raw food diets. Some foods need to be cooked to absorb their nutrients. Lycopene from tomatoes for example, (cooked tomatoes such as in sauce with a bit of fa for best absorption).

If you follow our easy instructions on “getting started” for beginners in the files, you should find it much easier to do CRON. I assume you’ve read Walford, a requirement for this group?

Please indicate which posts you’re referring to afa high protein diets. We do not advocate such diets here. See the files for typical meals and diets and what/how we eat.

Please give the citations for actual studies when referring to them, such as your reference to a study in a publication called “Molecular Degeneration”.

Welcome to the group!

On 6/2/10 11:36 PM, " helenmartirosova " <helenmartirosova@...> wrote:

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

[Guest guest]

Let’s try this again with a few corrections to my post:

On 6/3/10 7:26 AM, " Francesca Skelton " <fskelton@...> wrote:

I’d be careful about an all raw food diet. Some foods need to be cooked to absorb their nutrients. Lycopene from tomatoes for example, (cooked tomatoes such as in sauce with a bit of fat for best absorption).

If you follow our easy instructions on “getting started” for beginners in the files, you should find it much easier to do CRON. I assume you’ve read Walford, a requirement for this group?

Please indicate which posts you’re referring to afa high protein diets. We do not advocate such diets here. See the files for typical meals and diets and what/how we eat.

Please give the citations for actual studies when referring to them, such as your reference to a study in a publication called “Molecular Degeneration”.

Welcome to the group!

On 6/2/10 11:36 PM, " helenmartirosova " <helenmartirosova@...> wrote:

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

[Guest guest]

>>>

>>> I was wondering if anyone here is also familiar with the raw food diet and

if anyone has attempted to do a CRON version of this?

>>> (Raw food diets have some scientific back up as they do reduce the levels of

advanced glycolation end products).

This is really some twist on data, which is common amongst the raw food movement

and much of their evidence (cooking, enzymes, etc)

Yes, certain foods, when heated to higher temperatures, create AGE's more so

then other foods, which have been associated with several diseases, yet how that

data would be used to support a raw food diet is beyond me.

Jeff

[Guest guest]

The paper is free full-texts.

Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology.Pedrini S, C, Brautigam H, Schmeidler J, Ho L, Fraser P, Westaway D, Hyslop PS, s RN, Buxbaum JD, Pasinetti GM, Dickstein DL, Hof PR, Ehrlich ME, Gandy S.Mol Neurodegener. 2009 Oct 21;4:40.PMID: 19845940 [PubMed - in process]Free PMC ArticleFree texthttp://www.molecularneurodegeneration.com/content/4/1/40http://www.molecularneurodegeneration.com/content/pdf/1750-1326-4-40.pdf

ABSTRACT:

OBJECTIVE: Alzheimer's disease (AD) is a progressive neurodegenerative disease of the central nervous system (CNS). Recently, an increased interest in the role diet plays in the pathology of AD has resulted in a focus on the detrimental effects of diets high in cholesterol and fat and the beneficial effects of caloric restriction. The current study examines how dietary composition modulates cerebral amyloidosis and neuronal integrity in the TgCRND8 mouse model of AD.

METHODS: From 4 wks until 18 wks of age, male and female TgCRND8 mice were maintained on one of four diets: (1) reference (regular) commercial chow; (2) high fat/low carbohydrate custom chow (60 kcal% fat/30 kcal% protein/10 kcal% carbohydrate); (3) high protein/low carbohydrate custom chow (60 kcal% protein/30 kcal% fat/10 kcal% carbohydrate); or (4) high carbohydrate/low fat custom chow (60 kcal% carbohydrate/30 kcal% protein/10 kcal% fat). At age 18 wks, mice were sacrificed, and brains studied for (a) wet weight; ( solubilizable Abeta content by ELISA; © amyloid plaque burden; (d) stereologic analysis of selected hippocampal subregions.

RESULTS: Animals receiving a high fat diet showed increased brain levels of solubilizable Abeta, although we detected no effect on plaque burden. Unexpectedly, brains of mice fed a high protein/low carbohydrate diet were 5% lower in weight than brains from all other mice. In an effort to identify regions that might link loss of brain mass to cognitive function, we studied neuronal density and volume in hippocampal subregions. Neuronal density and volume in the hippocampal CA3 region of TgCRND8 mice tended to be lower in TgCRND8 mice receiving the high protein/low carbohydrate diet than in those receiving the regular chow. Neuronal density and volume were preserved in CA1 and in the dentate gyrus.

INTERPRETATION: Dissociation of Abeta changes from brain mass changes raises the possibility that diet plays a role not only in modulating amyloidosis but also in modulating neuronal vulnerability. However, in the absence of a study of the effects of a high protein/low carbohydrate diet on nontransgenic mice, one cannot be certain how much, if any, of the loss of brain mass exhibited by high protein/low carbohydrate diet-fed TgCRND8 mice was due to an interaction between cerebral amyloidosis and diet. Given the recent evidence that certain factors favor the maintenance of cognitive function in the face of substantial structural neuropathology, we propose that there might also exist factors that sensitize brain neurons to some forms of neurotoxicity, including, perhaps, amyloid neurotoxicity. Identification of these factors could help reconcile the poor clinicopathological correlation between cognitive status and structural neuropathology, including

amyloid pathology. -- Aalt Pater

From: helenmartirosova <helenmartirosova@...> Sent: Wed, June 2, 2010 8:36:10 PMSubject: [ ] Regarding high protein diets

Hello All I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios. I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this? (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets

(For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's) Thanks HM

[Guest guest]

Hi .

I should know better about citations! I just get so sick of keeping them

straight at work.So here is the full citation not the best article but

interesting: the high protein seemed to exacerbate neurotoxicity.

Pedrini etal. " Dietary composition modulates brain mass and solubilizable A & #946;

levels in a mouse model of aggressive Alzheimer's amyloid pathology. " Molecular

Neurodegeneration,09.

The diets I was referencing were from the posts that you guys had all the way

in the beginning (i.e. 2000) where there was a lot of discussion of increasing

protein intake (the Zone diet guidelines).

I have read a couple of CR books The Longevity diet, the CR way and the

Anti-Aging Plan by Walford.I put in an order for the 120 Year Diet and am

looking forward to it. But in the meantime I am really struggling to get of my

hypoglycemic sugar induced cycle so I can begin a healthier diet and transition

to CRON.

-HM

> >

> >>

> >>

> >>

> >>

> >>

> >> Hello All

> >>

> >> I am new to the site but wanted to introduce myself, I a grad student

> >> currently studying the link between Alzheimer's and diabetes. Ironically

> >> partially due to depression which compounded some bad eating choices I

> >> developed reactive hypoglycemia. I have significant interest in CRON for

> >> health reasons (and partially professional)but am a bit weary about having

to

> >> do so much work to measure everything that I eat for correct ratios.

> >>

> >> I was wondering if anyone here is also familiar with the raw food diet and

if

> >> anyone has attempted to do a CRON version of this?

> >> (Raw food diets have some scientific back up as they do reduce the levels

of

> >> advanced glycolation end products). I would love to try it out but am a bit

> >> scared about developing a deficiency.

> >>

> >> Additionally after reading earlier posts I noticed the popularity of high

> >> protein diets but I wanted to say that there are risk factors associated

with

> >> these type of diets (For example Molecular Neurodegenration published an

> >> article linking this type of diet to Alzheimer's)

> >> Thanks HM

> >>

> >>

> >>

> >>

> >>

> >

> >

> >

> >

> >

>

[Guest guest]

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said.. Regarding sugar metabolism (reactive hypoglycemia?) I have one suggested reading link. Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response. I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed literally as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways. http://drbass.com/rosedale2.html I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too. JROn Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

[Guest guest]

He has some pretty wild contentions. How does he know we “should” be living to 130-140? Nobody’s ever done it. And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate. Aging is a natural state that we can’t deny. Every living thing ages and eventually dies! We may be able to slow it down some, but nature eventually wins out.

I went to Rosedale’s website. He will soon be selling “products” - unfortunately.

On 6/5/10 6:20 PM, " john roberts " <robertsjohnh@...> wrote:

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said.. Regarding sugar metabolism (reactive hypoglycemia?) I have one suggested reading link.

Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response.

I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways.

http://drbass.com/rosedale2.html

I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too.

JR

On Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

[Guest guest]

This is correct Francesca!

 

On a word of caution regarding Alzheimer's and diet.

 

Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons.

 

Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's.

 

Best,

TR

On Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskelton@...> wrote:

 

He has some pretty wild contentions.  How does he know we “should” be living to 130-140? Nobody’s ever done it.  And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate.  Aging is a natural state that we can’t deny. Every living thing ages and eventually dies!  We may be able to slow it down some, but nature eventually wins out.

I went to Rosedale’s website.  He will soon be selling “products” - unfortunately.On 6/5/10 6:20 PM, " john roberts " <robertsjohnh@...> wrote:

     While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said..  Regarding sugar metabolism (reactive hypoglycemia?)

I have one suggested reading link.

Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response.

I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways.

http://drbass.com/rosedale2.html I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too.

JROn Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

 Hello All I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this? (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM       

[Guest guest]

If your conclusions about inflammation/excessive protein are based on a scientific study or studies, please post them. If they’re just your own opinions, fine, but state that. Important for credibility here.

Thanks.

On 6/8/10 12:52 PM, " Tamara Rajaram " <tamarar@...> wrote:

This is correct Francesca!

 

On a word of caution regarding Alzheimer's and diet.

 

Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons.

 

Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's.

 

Best,

TR

On Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskelton@...> wrote:

 

He has some pretty wild contentions.  How does he know we “should” be living to 130-140? Nobody’s ever done it.  And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate.  Aging is a natural state that we can’t deny. Every living thing ages and eventually dies!  We may be able to slow it down some, but nature eventually wins out.

I went to Rosedale’s website.  He will soon be selling “products” - unfortunately.

On 6/5/10 6:20 PM, " john roberts " <robertsjohnh@...> wrote:

 

 

   

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said..  Regarding sugar metabolism (reactive hypoglycemia?)

I have one suggested reading link.

Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response.

I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways.

http://drbass.com/rosedale2.html

I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too.

JR

On Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

 

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

 

  

 

   

[Guest guest]

You can look at NUMEROUS articles in medline to see the association with inflammation and alzheimer's and the debate as to development and cause with plaque versus tangles. The theory behind development of these is just that, theories. So even the research linking protein or carbs or anything else in one's diet for that matter would only be just theory. 

At this point, if there were research which was reproducable consistently with same results, we would be closer to cure for this disease. Hence my comments. All one can gleam from research with alzheimer's at this point is correlations with a list of things like inflammation (ie why aspirin or advil users have a lower risk profile for the disease etc). 

My point was that research on Alzhiemer's and diet have not been reliable and so I would not draw conclusions on any reports related to it yet until they are reproducible and reliable. We only recommend that what is good for the heart is good for the brain.

Hope this explains my points.T-On Tue, Jun 8, 2010 at 10:32 AM, Francesca Skelton <fskelton@...> wrote:

 

If your conclusions about inflammation/excessive protein are based on a scientific study or studies, please post them.  If they’re just your own opinions, fine, but state that.  Important for credibility here.

Thanks.

On 6/8/10 12:52 PM, " Tamara Rajaram " <tamarar@...> wrote:

 

 

   

This is correct Francesca!

 

On a word of caution regarding Alzheimer's and diet.

 

Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons.

 

Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's.

 

Best,

TR

On Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskelton@...> wrote:

 

He has some pretty wild contentions.  How does he know we “should” be living to 130-140? Nobody’s ever done it.  And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate.  Aging is a natural state that we can’t deny. Every living thing ages and eventually dies!  We may be able to slow it down some, but nature eventually wins out.

I went to Rosedale’s website.  He will soon be selling “products” - unfortunately.

On 6/5/10 6:20 PM, " john roberts " <robertsjohnh@...> wrote:

 

 

   

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said..  Regarding sugar metabolism (reactive hypoglycemia?)

I have one suggested reading link.

Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response.

I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways.

http://drbass.com/rosedale2.html

I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too.

JR

On Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

 

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

 

  

 

   

 

   

[Guest guest]

On Jun 8, 2010, at 11:52 AM, Tamara Rajaram wrote:

This is correct Francesca!

On a word of caution regarding Alzheimer's and diet.

Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). Not sure I follow.. There seems to be radically different energy pathways for our always beating heart muscle, and brain energy metabolism, I recall one study suggesting our brain recharges it's deep energy stores overnight while we sleep (there was some rat/mouse research into this, but they had to sacrifice the animals to take each data point so it was hard to control for and not much work was done in this specific area.) The heart is in intimate contact with most of out blood flow, while the brain blood and associated fluids system is somewhat slower turnover and more complex. The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons.

The plaques do appear like a typical body defense mechanism to protect against some stressor (like inflammation?) I was ready to dismiss your comments but with a little quick googling there is apparently a positive correlation with type II diabetes and Alzheimer risk. http://www.time.com/time/health/article/0,8599,1215243,00.html This does seem to be yet another positive benefit from energy balance management (CR), moderate exercise, brushing our teeth, etc. All of which reduce inflammation.

Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's.

I'll take your word for that. :-) JR

Best,

TR

On Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskeltonerols> wrote:

He has some pretty wild contentions. How does he know we “should” be living to 130-140? Nobody’s ever done it. And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate. Aging is a natural state that we can’t deny. Every living thing ages and eventually dies! We may be able to slow it down some, but nature eventually wins out.

I went to Rosedale’s website. He will soon be selling “products” - unfortunately.On 6/5/10 6:20 PM, "john roberts" <robertsjohnhbellsouth (DOT) net> wrote:

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said.. Regarding sugar metabolism (reactive hypoglycemia?)

I have one suggested reading link.

Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response.

I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways.

http://drbass.com/rosedale2.html I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too.

JROn Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

Hello All I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this? (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

[Guest guest]

That explains nothing to me.

What is "inflammation"?

Pain?

Something we can measure?

Yes, I see little advice in dementia articles.

Regards

Re: [ ] Regarding high protein diets

You can look at NUMEROUS articles in medline to see the association with inflammation and alzheimer's and the debate as to development and cause with plaque versus tangles. The theory behind development of these is just that, theories. So even the research linking protein or carbs or anything else in one's diet for that matter would only be just theory.

At this point, if there were research which was reproducable consistently with same results, we would be closer to cure for this disease. Hence my comments. All one can gleam from research with alzheimer's at this point is correlations with a list of things like inflammation (ie why aspirin or advil users have a lower risk profile for the disease etc).

My point was that research on Alzhiemer's and diet have not been reliable and so I would not draw conclusions on any reports related to it yet until they are reproducible and reliable. We only recommend that what is good for the heart is good for the brain.

Hope this explains my points.

T-

On Tue, Jun 8, 2010 at 10:32 AM, Francesca Skelton <fskeltonerols> wrote:

If your conclusions about inflammation/excessive protein are based on a scientific study or studies, please post them. If they’re just your own opinions, fine, but state that. Important for credibility here.Thanks.

On 6/8/10 12:52 PM, "Tamara Rajaram" <tamarargmail> wrote:

This is correct Francesca! On a word of caution regarding Alzheimer's and diet. Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons. Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's. Best,TROn Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskeltonerols> wrote:

He has some pretty wild contentions. How does he know we “should” be living to 130-140? Nobody’s ever done it. And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate. Aging is a natural state that we can’t deny. Every living thing ages and eventually dies! We may be able to slow it down some, but nature eventually wins out.I went to Rosedale’s website. He will soon be selling “products” - unfortunately.On 6/5/10 6:20 PM, "john roberts" <robertsjohnhbellsouth (DOT) net> wrote:

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said.. Regarding sugar metabolism (reactive hypoglycemia?)I have one suggested reading link. Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response. I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways. http://drbass.com/rosedale2.html I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too. JROn Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

Hello All I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios. I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this? (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's) Thanks HM

__________ NOD32 4893 (20100224) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com

[Guest guest]

c reactive protein is generally considered a useful marker for inflammationhttp://en.wikipedia.org/wiki/C-reactive_proteinI am not aware of a correlation to protein consumption and inflammation, but infection, injury, smoking, and too much energy intake does seem associated with it. I guess if that too much energy intake is protein it could be better or worse than too much of some other macro-nutirent, but i'm not prepared to say any macro-nutirent is less harmful than another in excess.JROn Jun 8, 2010, at 2:55 PM, jwwright wrote:

That explains nothing to me.

What is "inflammation"?

Pain?

Something we can measure?

Yes, I see little advice in dementia articles.

Regards

Re: [ ] Regarding high protein diets

You can look at NUMEROUS articles in medline to see the association with inflammation and alzheimer's and the debate as to development and cause with plaque versus tangles. The theory behind development of these is just that, theories. So even the research linking protein or carbs or anything else in one's diet for that matter would only be just theory.

At this point, if there were research which was reproducable consistently with same results, we would be closer to cure for this disease. Hence my comments. All one can gleam from research with alzheimer's at this point is correlations with a list of things like inflammation (ie why aspirin or advil users have a lower risk profile for the disease etc).

My point was that research on Alzhiemer's and diet have not been reliable and so I would not draw conclusions on any reports related to it yet until they are reproducible and reliable. We only recommend that what is good for the heart is good for the brain.

Hope this explains my points.

T-

On Tue, Jun 8, 2010 at 10:32 AM, Francesca Skelton <fskeltonerols> wrote:

If your conclusions about inflammation/excessive protein are based on a scientific study or studies, please post them. If they’re just your own opinions, fine, but state that. Important for credibility here.Thanks.

On 6/8/10 12:52 PM, "Tamara Rajaram" <tamarargmail> wrote:

This is correct Francesca! On a word of caution regarding Alzheimer's and diet. Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons. Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's. Best,TROn Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskeltonerols> wrote:

He has some pretty wild contentions. How does he know we “should” be living to 130-140? Nobody’s ever done it. And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate. Aging is a natural state that we can’t deny. Every living thing ages and eventually dies! We may be able to slow it down some, but nature eventually wins out.I went to Rosedale’s website. He will soon be selling “products” - unfortunately.On 6/5/10 6:20 PM, "john roberts" <robertsjohnhbellsouth (DOT) net> wrote:

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said.. Regarding sugar metabolism (reactive hypoglycemia?)I have one suggested reading link. Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response. I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways. http://drbass.com/rosedale2.html I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too. JROn Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

Hello All I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios. I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this? (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's) Thanks HM

__________ NOD32 4893 (20100224) Information __________This message was checked by NOD32 antivirus system.http://www.eset.com

[Guest guest]

Which is why I asked if there were any studies about high protein and inflammation.

On 6/8/10 5:07 PM, " john roberts " <robertsjohnh@...> wrote:

c reactive protein is generally considered a useful marker for inflammation

http://en.wikipedia.org/wiki/C-reactive_protein

<http://en.wikipedia.org/wiki/C-reactive_protein> I am not aware of a correlation to protein consumption and inflammation, but infection, injury, smoking, and too much energy intake does seem associated with it. I guess if that too much energy intake is protein it could be better or worse than too much of some other macro-nutirent, but i'm not prepared to say any macro-nutirent is less harmful than another in excess.

JR

On Jun 8, 2010, at 2:55 PM, jwwright wrote:

That explains nothing to me.

What is " inflammation " ?

Pain?

Something we can measure?

Yes, I see little advice in dementia articles.

Regards

Re: [ ] Regarding high protein diets

You can look at NUMEROUS articles in medline to see the association with inflammation and alzheimer's and the debate as to development and cause with plaque versus tangles. The theory behind development of these is just that, theories. So even the research linking protein or carbs or anything else in one's diet for that matter would only be just theory.

At this point, if there were research which was reproducable consistently with same results, we would be closer to cure for this disease. Hence my comments. All one can gleam from research with alzheimer's at this point is correlations with a list of things like inflammation (ie why aspirin or advil users have a lower risk profile for the disease etc).

My point was that research on Alzhiemer's and diet have not been reliable and so I would not draw conclusions on any reports related to it yet until they are reproducible and reliable. We only recommend that what is good for the heart is good for the brain.

Hope this explains my points.

T-

On Tue, Jun 8, 2010 at 10:32 AM, Francesca Skelton <fskelton@...> wrote:

If your conclusions about inflammation/excessive protein are based on a scientific study or studies, please post them. If they’re just your own opinions, fine, but state that. Important for credibility here.

Thanks.

On 6/8/10 12:52 PM, " Tamara Rajaram " <tamarar@...> wrote:

This is correct Francesca!

On a word of caution regarding Alzheimer's and diet.

Please remember that what is good for your heart is good for your brain (this applies to diet and exercise etc). The problem in this disease is inflammation not quantity of protein versus carbs etc. I was privy to all research in this area before it was published and the one thing so critical is minimizing inflammation in the body. If you have so much protein running through the body while having a higher level of inflammation, then your body can not adequately breakdown the large protiens and problems ensue. Many similiarities with this disease and Diabetes are for the same reasons.

Lastly, amyloid plaques versus neurofibrilary tangles are still a debate with Alzheimer's.

Best,

TR

On Sat, Jun 5, 2010 at 4:51 PM, Francesca Skelton <fskelton@...> wrote:

He has some pretty wild contentions. How does he know we “should” be living to 130-140? Nobody’s ever done it. And I’m always skeptical about the statement that “aging is a disease” which some of the extremists like Aubrey DeGray like to postulate. Aging is a natural state that we can’t deny. Every living thing ages and eventually dies! We may be able to slow it down some, but nature eventually wins out.

I went to Rosedale’s website. He will soon be selling “products” - unfortunately.

On 6/5/10 6:20 PM, " john roberts " <robertsjohnh@...> wrote:

While I will keep my mouth shut about the raw foodism screed, so I'll leave that at +1 to whatever Jeffery said.. Regarding sugar metabolism (reactive hypoglycemia?)

I have one suggested reading link.

Believe it or not, our sugar metabolism insulin response is affected by more than the obvious last meal ingested. While what we consume is the literal cause of whatever response, how our body reacts to and deals with consumed sugar is also affect by the state of our musculature. So while not very obvious there can be a connection between exercise patterns (or muscle tone) and insulin response.

I highly recommend reading this classic lecture by Dr. Rosedale on the subject of insulin/sugar and related metabolic interactions. I believe this lecture was to a lay group and transcribed litera! lly as given so perhaps not medically strict. It has also been co-opted by sundry web merchants to ply whatever, so please don't let that taint the content of this lecture. It is IMO good solid basic information we should all know about our insulin pathways.

http://drbass.com/rosedale2.html

I am not endorsing Dr. Bass's website, by association or even Rosedale's (later) diet book.. Just this one lecture. I had to search around to find this free copy. Mercola seems to be riding on this coat tail, too.

JR

On Jun 2, 2010, at 10:36 PM, helenmartirosova wrote:

Hello All

I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

(Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

Thanks HM

__________ NOD32 4893 (20100224) Information __________

This message was checked by NOD32 antivirus system.

http://www.eset.com <http://www.eset.com/>

[Guest guest]

There is some speculation that higher protein intake could negate CRON via

increased IGF-1 levels. Animals respond to CRON diet with reduced IGF-1 levels,

humans not so much, and it's speculated that it's the lower IGF-1 levels that

account for the longevity effect. See this link :

http://news.wustl.edu/news/Pages/12662.aspx

--- In , " helenmartirosova " <helenmartirosova@...>

wrote:

>

> Hello All

>

> I am new to the site but wanted to introduce myself, I a grad student

currently studying the link between Alzheimer's and diabetes. Ironically

partially due to depression which compounded some bad eating choices I developed

reactive hypoglycemia. I have significant interest in CRON for health reasons

(and partially professional)but am a bit weary about having to do so much work

to measure everything that I eat for correct ratios.

>

> I was wondering if anyone here is also familiar with the raw food diet and if

anyone has attempted to do a CRON version of this?

> (Raw food diets have some scientific back up as they do reduce the levels of

advanced glycolation end products). I would love to try it out but am a bit

scared about developing a deficiency.

>

> Additionally after reading earlier posts I noticed the popularity of high

protein diets but I wanted to say that there are risk factors associated with

these type of diets (For example Molecular Neurodegenration published an article

linking this type of diet to Alzheimer's)

> Thanks HM

>

[Guest guest]

Speculation is the right word. The numbers of people cited in this study are very small. Too small to make any final conclusions. But thanks – interesting nevertheless. I believe this was posted when it first came out in 2008.

On 6/9/10 9:18 AM, " My Lord " <herbslocomb@...> wrote:

There is some speculation that higher protein intake could negate CRON via increased IGF-1 levels. Animals respond to CRON diet with reduced IGF-1 levels, humans not so much, and it's speculated that it's the lower IGF-1 levels that account for the longevity effect. See this link :

http://news.wustl.edu/news/Pages/12662.aspx

>

> Hello All

>

> I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

>

> I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

> (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

>

> Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

> Thanks HM

>

[Guest guest]

jwwright wrote:

>

>

> That explains nothing to me.

> What is " inflammation " ?

> Pain?

> Something we can measure?

> Yes, I see little advice in dementia articles.

>

" Inflammation " is a word that I see kicking around too much these days.

By unhappy circumstance I got bloodwork the day after I whacked my

quadraceps muscle (largest in the body) and got a contusion that still

hurts two weeks later. I'm also allergic to just about everything my

allergist prick tested me for, so I was having sneezing fits because of

tree pollen and hadn't started taking Zyrtec to suppress the allergic

response.

My C-Reactive Protein measured off the bottom of the scale (they

only gave me a " less than " reading) so I've got no idea of what it

measures. It certainly didn't detect two kinds of inflammation that

were making me thoroughly miserable.

A friend of mine went to his doc the other day and was told that his

doc wouldn't prescribe any medicine or do anything for his high CRP test

because there wasn't any solid scientific case for treating it. Lately

the makers of Crestor, a statin drug, have been pushing Crestor for

people with elevated CRP based on a single study, but the health care

economics (and risk of side effects) may not add up for this application:

http://www.nytimes.com/2010/03/31/business/31statins.html

[Guest guest]

While some CRONies are trying to achieve low levels of IGF-1, it is too early to

tell if this is a useful strategy for longevity. IGF-1 is associated with

muscle growth and tissue repair, and IGF-1 levels increase by consuming protein.

The other part of the picture is that *exercise* reduces levels of IGF-1.

http://www.jssm.org/vol6/n4/8/v6n4-8pdf.pdf

So, the lesson may be that if you eat a higher protein diet you *must* exercise

to keep your IGF-1 levels normal. Or conversely, if you exercise, you may need

the extra protein to rebuild your muscles.

Tony

>

> There is some speculation that higher protein intake could negate CRON via

increased IGF-1 levels. Animals respond to CRON diet with reduced IGF-1 levels,

humans not so much, and it's speculated that it's the lower IGF-1 levels that

account for the longevity effect. See this link :

>

> http://news.wustl.edu/news/Pages/12662.aspx

>

> --- In , " helenmartirosova " <helenmartirosova@>

wrote:

> >

> > Hello All

> >

> > I am new to the site but wanted to introduce myself, I a grad student

currently studying the link between Alzheimer's and diabetes. Ironically

partially due to depression which compounded some bad eating choices I developed

reactive hypoglycemia. I have significant interest in CRON for health reasons

(and partially professional)but am a bit weary about having to do so much work

to measure everything that I eat for correct ratios.

> >

> > I was wondering if anyone here is also familiar with the raw food diet and

if anyone has attempted to do a CRON version of this?

> > (Raw food diets have some scientific back up as they do reduce the levels of

advanced glycolation end products). I would love to try it out but am a bit

scared about developing a deficiency.

> >

> > Additionally after reading earlier posts I noticed the popularity of high

protein diets but I wanted to say that there are risk factors associated with

these type of diets (For example Molecular Neurodegenration published an article

linking this type of diet to Alzheimer's)

> > Thanks HM

> >

>

[Guest guest]

IGF-1 seems like a good thing to avoid in excess, but this does seem like a lot of conjecture. Regarding the correlation with exercise and protein/IGF sensitivity, perhaps the exercise "consumes" free protein for repair and muscular remodeling, making less available to stimulate IGF production. It seems we should be able to find a number of chronically protein restricted populations from poor regions around the world. AFAIK nobody in the world eats as much protein as we (the US) do. While these population studies may be light on other important nutrients besides the protein, so not well controlled to parse out longevity. This is worth study, and attractive in the something for (almost) nothing we humans like so much, but until we have credible (human) results, this is just another theory. JROn Jun 9, 2010, at 9:31 AM, citpeks wrote:

While some CRONies are trying to achieve low levels of IGF-1, it is too early to tell if this is a useful strategy for longevity. IGF-1 is associated with muscle growth and tissue repair, and IGF-1 levels increase by consuming protein.

The other part of the picture is that *exercise* reduces levels of IGF-1.

http://www.jssm.org/vol6/n4/8/v6n4-8pdf.pdf

So, the lesson may be that if you eat a higher protein diet you *must* exercise to keep your IGF-1 levels normal. Or conversely, if you exercise, you may need the extra protein to rebuild your muscles.

Tony

> >

> > Hello All

> >

> > I am new to the site but wanted to introduce myself, I a grad student currently studying the link between Alzheimer's and diabetes. Ironically partially due to depression which compounded some bad eating choices I developed reactive hypoglycemia. I have significant interest in CRON for health reasons (and partially professional)but am a bit weary about having to do so much work to measure everything that I eat for correct ratios.

> >

> > I was wondering if anyone here is also familiar with the raw food diet and if anyone has attempted to do a CRON version of this?

> > (Raw food diets have some scientific back up as they do reduce the levels of advanced glycolation end products). I would love to try it out but am a bit scared about developing a deficiency.

> >

> > Additionally after reading earlier posts I noticed the popularity of high protein diets but I wanted to say that there are risk factors associated with these type of diets (For example Molecular Neurodegenration published an article linking this type of diet to Alzheimer's)

> > Thanks HM

> >

>