Protein and insulin

[Guest guest]

Realistically, it is not possible to consider the protein insulin connection

because a high protein diet with no carbohydrates or fat cannot be sustained.

(See rabbit starvation, http://en.wikipedia.org/wiki/Rabbit_starvation)

However, the following article concludes " This study demonstrates that

consumption of a diet with increased protein and a reduced CHO/protein ratio

stabilizes blood glucose during nonabsorptive periods and reduces the

postprandial insulin response. "

Tony

http://www.ncbi.nlm.nih.gov/pubmed/12566475

J Nutr. 2003 Feb;133(2):405-10.

Increased dietary protein modifies glucose and insulin homeostasis in adult

women during weight loss.

Layman DK, Shiue H, Sather C, kson DJ, Baum J.

Department of Food Science and Human Nutrition, University of Illinois at

Urbana-Champaign, Urbana, IL 61801, USA. d-layman@...

Abstract

Amino acids interact with glucose metabolism both as carbon substrates and by

recycling glucose carbon via alanine and glutamine; however, the effect of

protein intake on glucose homeostasis during weight loss remains unknown. This

study tests the hypothesis that a moderate increase in dietary protein with a

corresponding reduction of carbohydrates (CHO) stabilizes fasting and

postprandial blood glucose and insulin during weight loss. Adult women (n = 24;

>15% above ideal body weight) were assigned to either a Protein Group [protein:

1.6 g/(kg. d); CHO <40% of energy] or CHO Group [protein: 0.8 g/(kg. d); CHO

>55%]. Diets were equal in energy (7100 kJ/d) and fat (50 g/d). After 10 wk, the

Protein Group lost 7.53 +/- 1.44 kg and the CHO Group lost 6.96 +/- 1.36 kg.

Plasma amino acids, glucose and insulin were determined after a 12-h fast and 2

h after a 1.67 MJ test meal containing either 39 g CHO, 33 g protein and 13 g

fat (Protein Group) or 57 g CHO, 12 g protein and 14 g fat (CHO Group). After 10

wk, subjects in the CHO Group had lower fasting (4.34 +/- 0.10 vs 4.89 +/- 0.11

mmol/L) and postprandial blood glucose (3.77 +/- 0.14 vs. 4.33 +/- 0.15 mmol/L)

and an elevated insulin response to meals (207 +/- 21 vs. 75 +/- 18 pmol/L).

This study demonstrates that consumption of a diet with increased protein and a

reduced CHO/protein ratio stabilizes blood glucose during nonabsorptive periods

and reduces the postprandial insulin response.

PMID: 12566475

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> & gt; & gt; Many CRONies try to avoid blood sugar spikes by eating complex

carbohydrates, by adding fiber to their diet, and by eating several small meals,

rather than fewer large meals. Regardless of how you space your meals,

carbohydrates always stimulate an insulin response that causes excess glucose to

be stored as fat.

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> & gt; While I understand the logic and application of this last statement for

anyone who is in a constant state of positive energy balance, for someone

following a CR diet, where would the extra glucose (calories) be coming from?

Anyone following CR would be in a lower steady state or a negative energy

balance.

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> & gt; Protein which may not stimulate an spike in glucose, also stimulates an

increase in insulin as the insulin index showed.

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> & gt; Regards

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> & gt; Jeff

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