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Re: What Dose of Oral Vitamin D Do You Need to Prevent Cancer?

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AFAIK this is misleading. There is not yet any proof that Vitamin D prevents cancer, only conjecture. If there is such published scientific evidence (which would require a study on humans of many years duration), please do post it.

On 2/22/11 10:51 AM, " grudendon " <grudendon@...> wrote:

Researchers have reported that a much higher intake of vitamin D is needed to reach blood levels that can prevent breast cancer and other major diseases than had been originally thought.

They found that daily intakes of vitamin D by adults in the range of 4000-8000 IU are needed to maintain blood levels of vitamin D metabolites in the range needed to reduce by about half the risk of breast cancer, colon cancer, multiple sclerosis, and type 1 diabetes. While an Institute of Medicine committee has stated that 4000 IU/day is a safe dosage, their recommended minimum daily intake is only 600 IU/day.

According to the study in the journal Anticancer Research:

" The supplemental dose ensuring that 97.5 percent of this population achieved a serum 25(OH)D of at least 40 ng/ml was 9,600 IU/d ... Universal intake of up to 40,000 IU vitamin D per day is unlikely to result in vitamin D toxicity. "

http://www.iiar-anticancer.org/openAR/journals/index.php/anticancer/article/view/215

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This is an old and somewhat controversial discussion. The Kime book "sunlight" has an entire chapter on Sunlight and Cancer, and that one chapter alone has 8 pages of scientific footnotes. Cancer is a complex subject and Vit D supplement research is conflicted as there are multiple variants of Vit D, generated by actual sun exposure. Sunlight is a double edged sword as beneficial vit D comes with the risky baggage of exposure to solar radiation. Vit D clearly does not prevent skin cancer. while is could be beneficial against other cancers. As always, avoid simple answers to complex questions. JRPS: The Kime book was published in 1980 and I suspect there has been more scientific work done since then. As with most nutrition science I fear that opinions (and commercial interests) surrounding the pros and cons of sunlight may dominate the public discussion. Just like we can wrestle about what kind of sugar is "less bad" instead of the fat elephant in the room (energy balance). On Feb 22, 2011, at 11:16 AM, Francesca Skelton wrote:

AFAIK this is misleading. There is not yet any proof that Vitamin D prevents cancer, only conjecture. If there is such published scientific evidence (which would require a study on humans of many years duration), please do post it.

On 2/22/11 10:51 AM, "grudendon" <grudendon@...> wrote:

Researchers have reported that a much higher intake of vitamin D is needed to reach blood levels that can prevent breast cancer and other major diseases than had been originally thought.

They found that daily intakes of vitamin D by adults in the range of 4000-8000 IU are needed to maintain blood levels of vitamin D metabolites in the range needed to reduce by about half the risk of breast cancer, colon cancer, multiple sclerosis, and type 1 diabetes. While an Institute of Medicine committee has stated that 4000 IU/day is a safe dosage, their recommended minimum daily intake is only 600 IU/day.

According to the study in the journal Anticancer Research:

"The supplemental dose ensuring that 97.5 percent of this population achieved a serum 25(OH)D of at least 40 ng/ml was 9,600 IU/d ... Universal intake of up to 40,000 IU vitamin D per day is unlikely to result in vitamin D toxicity."

http://www.iiar-anticancer.org/openAR/journals/index.php/anticancer/article/view/215

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Two years ago, with 1000 IU/day of Vitamin D3, my level of serum 25(OH)D was 36

ng/ml. Last year, I started taking 2000 IU/day and my level actually dropped to

34 ng/ml.

The RDA oral dosage for Vitamin D has probably been grossly underestimated for

the general population. Since I don't get much sun, this year I started taking

8,000 IU/day to try to achieve a blood level in the mid 40s ng/ml.

I will find out how this works out next November when I get my physical.

Whether Vitamin D has anticancer effect or not, it seems prudent to try to get

the blood level to the middle of the normal range instead of at the bottom.

Tony

http://www.scientificpsychic.com/health/vitamins.html

>

> Researchers have reported that a much higher intake of vitamin D is needed to

reach blood levels that can prevent breast cancer and other major diseases than

had been originally thought.

>

> They found that daily intakes of vitamin D by adults in the range of 4000-8000

IU are needed to maintain blood levels of vitamin D metabolites in the range

needed to reduce by about half the risk of breast cancer, colon cancer, multiple

sclerosis, and type 1 diabetes. While an Institute of Medicine committee has

stated that 4000 IU/day is a safe dosage, their recommended minimum daily intake

is only 600 IU/day.

>

> According to the study in the journal Anticancer Research:

>

> " The supplemental dose ensuring that 97.5 percent of this population achieved

a serum 25(OH)D of at least 40 ng/ml was 9,600 IU/d ... Universal intake of up

to 40,000 IU vitamin D per day is unlikely to result in vitamin D toxicity. "

>

>

>

http://www.iiar-anticancer.org/openAR/journals/index.php/anticancer/article/view\

/215

>

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For what it’s worth, I’ve been taking 5000 IU/day for about four years, and had 46.8 ng/ml last month. Maco From: [mailto: ] On Behalf Of citpeksSent: Tuesday, March 01, 2011 12:26 PM Subject: [ ] Re: What Dose of Oral Vitamin D Do You Need to Prevent Cancer? Two years ago, with 1000 IU/day of Vitamin D3, my level of serum 25(OH)D was 36 ng/ml. Last year, I started taking 2000 IU/day and my level actually dropped to 34 ng/ml. The RDA oral dosage for Vitamin D has probably been grossly underestimated for the general population. Since I don't get much sun, this year I started taking 8,000 IU/day to try to achieve a blood level in the mid 40s ng/ml.I will find out how this works out next November when I get my physical. Whether Vitamin D has anticancer effect or not, it seems prudent to try to get the blood level to the middle of the normal range instead of at the bottom.Tonyhttp://www.scientificpsychic.com/health/vitamins.html>> Researchers have reported that a much higher intake of vitamin D is needed to reach blood levels that can prevent breast cancer and other major diseases than had been originally thought.> > They found that daily intakes of vitamin D by adults in the range of 4000-8000 IU are needed to maintain blood levels of vitamin D metabolites in the range needed to reduce by about half the risk of breast cancer, colon cancer, multiple sclerosis, and type 1 diabetes. While an Institute of Medicine committee has stated that 4000 IU/day is a safe dosage, their recommended minimum daily intake is only 600 IU/day.> > According to the study in the journal Anticancer Research:> > " The supplemental dose ensuring that 97.5 percent of this population achieved a serum 25(OH)D of at least 40 ng/ml was 9,600 IU/d ... Universal intake of up to 40,000 IU vitamin D per day is unlikely to result in vitamin D toxicity. " > > > http://www.iiar-anticancer.org/openAR/journals/index.php/anticancer/article/view/215>

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