Dwarfism, IGF, diabetes, cancer, and longevity

[Guest guest]

An article in today's WSJ mentions a pair of researchers looking into connection

between IGF (insulin like growth factor) and cancer, diabetes, and longevity.

First a study of Laron syndrome (dwarfism) subjects (in Ecudor) showed a

positive correlation with IGF, diabetes and cancer (i.e. less IGF correlates to

less cancer and diabetes), another researcher in Ca. was looking into the

connection to longevity.

For the record dietary restriction also suppresses IGF.

Some may find irony, in that the drug industry spent a lot of time and money

trying to increase growth hormone production. They abandoned their pursuit

because of negative side effects... perhaps side effects like death?

The correlation with cancer, which is growth run amok, seems logical. I don't

immediately see the connection to diabetes, but I am just an interested

observer.

JR

[Guest guest]

In the “Youth Pill”, the book I recently discussed, the unacceptable “side effects” of growth hormone, (like dying) are mentioned. Other fads with bad side effects are also covered.

Again I highly recommend reading it. And posting things I may have overlooked.

Can you post the WSJ article?

On 2/17/11 1:04 PM, " john roberts " <robertsjohnh@...> wrote:

An article in today's WSJ mentions a pair of researchers looking into connection between IGF (insulin like growth factor) and cancer, diabetes, and longevity. First a study of Laron syndrome (dwarfism) subjects (in Ecudor) showed a positive correlation with IGF, diabetes and cancer (i.e. less IGF correlates to less cancer and diabetes), another researcher in Ca. was looking into the connection to longevity.

For the record dietary restriction also suppresses IGF.

Some may find irony, in that the drug industry spent a lot of time and money trying to increase growth hormone production. They abandoned their pursuit because of negative side effects... perhaps side effects like death?

The correlation with cancer, which is growth run amok, seems logical. I don't immediately see the connection to diabetes, but I am just an interested observer.

JR

[Guest guest]

a quick google turns up this http://online.wsj.com/article/SB10001424052748703961104576148422547757048.htmlI don't know how long it is available or who can see it... I read the old school paper version of the WSJ. JROn Feb 17, 2011, at 1:24 PM, Francesca Skelton wrote:

In the “Youth Pill”, the book I recently discussed, the unacceptable “side effects” of growth hormone, (like dying) are mentioned. Other fads with bad side effects are also covered.

Again I highly recommend reading it. And posting things I may have overlooked.

Can you post the WSJ article?

On 2/17/11 1:04 PM, "john roberts" <robertsjohnh@...> wrote:

An article in today's WSJ mentions a pair of researchers looking into connection between IGF (insulin like growth factor) and cancer, diabetes, and longevity. First a study of Laron syndrome (dwarfism) subjects (in Ecudor) showed a positive correlation with IGF, diabetes and cancer (i.e. less IGF correlates to less cancer and diabetes), another researcher in Ca. was looking into the connection to longevity.

For the record dietary restriction also suppresses IGF.

Some may find irony, in that the drug industry spent a lot of time and money trying to increase growth hormone production. They abandoned their pursuit because of negative side effects... perhaps side effects like death?

The correlation with cancer, which is growth run amok, seems logical. I don't immediately see the connection to diabetes, but I am just an interested observer.

JR

[Guest guest]

Couldn’t get the entire article with that URL. But here it is from another newspaper:

http://www.smh.com.au/lifestyle/lifematters/little-secret-that-might-save-big-problems-of-diabetes-cancer-20110217-1ayad.html?from=smh_sb

On 2/17/11 2:33 PM, " john roberts " <robertsjohnh@...> wrote:

a quick google turns up this

http://online.wsj.com/article/SB10001424052748703961104576148422547757048.html

<http://online.wsj.com/article/SB10001424052748703961104576148422547757048.html> I don't know how long it is available or who can see it... I read the old school paper version of the WSJ.

JR

On Feb 17, 2011, at 1:24 PM, Francesca Skelton wrote:

In the “Youth Pill”, the book I recently discussed, the unacceptable “side effects” of growth hormone, (like dying) are mentioned. Other fads with bad side effects are also covered.

Again I highly recommend reading it. And posting things I may have overlooked.

Can you post the WSJ article?

On 2/17/11 1:04 PM, " john roberts " <robertsjohnh@...> wrote:

An article in today's WSJ mentions a pair of researchers looking into connection between IGF (insulin like growth factor) and cancer, diabetes, and longevity. First a study of Laron syndrome (dwarfism) subjects (in Ecudor) showed a positive correlation with IGF, diabetes and cancer (i.e. less IGF correlates to less cancer and diabetes), another researcher in Ca. was looking into the connection to longevity.

For the record dietary restriction also suppresses IGF.

Some may find irony, in that the drug industry spent a lot of time and money trying to increase growth hormone production. They abandoned their pursuit because of negative side effects... perhaps side effects like death?

The correlation with cancer, which is growth run amok, seems logical. I don't immediately see the connection to diabetes, but I am just an interested observer.

JR

[Guest guest]

†hat would be a different article but covering the same studies.. Since it's dated tomorrow (thanks to it being tomorrow in oz), it isn't clear which was first , not that it matters. JR On Feb 17, 2011, at 1:36 PM, Francesca Skelton wrote:

Couldn’t get the entire article with that URL. But here it is from another newspaper:

http://www.smh.com.au/lifestyle/lifematters/little-secret-that-might-save-big-problems-of-diabetes-cancer-20110217-1ayad.html?from=smh_sb

On 2/17/11 2:33 PM, "john roberts" <robertsjohnh@...> wrote:

a quick google turns up this

http://online.wsj.com/article/SB10001424052748703961104576148422547757048.html

<http://online.wsj.com/article/SB10001424052748703961104576148422547757048.html> I don't know how long it is available or who can see it... I read the old school paper version of the WSJ.

JR

On Feb 17, 2011, at 1:24 PM, Francesca Skelton wrote:

In the “Youth Pill”, the book I recently discussed, the unacceptable “side effects” of growth hormone, (like dying) are mentioned. Other fads with bad side effects are also covered.

Again I highly recommend reading it. And posting things I may have overlooked.

Can you post the WSJ article?

On 2/17/11 1:04 PM, "john roberts" <robertsjohnh@...> wrote:

An article in today's WSJ mentions a pair of researchers looking into connection between IGF (insulin like growth factor) and cancer, diabetes, and longevity. First a study of Laron syndrome (dwarfism) subjects (in Ecudor) showed a positive correlation with IGF, diabetes and cancer (i.e. less IGF correlates to less cancer and diabetes), another researcher in Ca. was looking into the connection to longevity.

For the record dietary restriction also suppresses IGF.

Some may find irony, in that the drug industry spent a lot of time and money trying to increase growth hormone production. They abandoned their pursuit because of negative side effects... perhaps side effects like death?

The correlation with cancer, which is growth run amok, seems logical. I don't immediately see the connection to diabetes, but I am just an interested observer.

JR