The flavonoid luteolin suppresses relapse and reverses symptoms in EAE

[Guest guest]

Yes, EAE's been cured many times (unlike MS), but this is kind of

interesting,

from the Journal of Experimental Medicine:

http://www.jem.org/cgi/content/abstract/200/12/1667

Flavonoids Influence Monocytic GTPase Activity and Are Protective in

Experimental Allergic Encephalitis

......we treated rats sensitized for acute and chronic experimental

allergic encephalomyelitis, an experimental model of MS, with

flavonoids. We demonstrated that the flavonoid luteolin

substantially suppressed clinical symptoms and prevented relapse

when administered either before or after disease onset.....Oral

administration of luteolin also significantly reduced clinical

symptoms.

See here for another paper by the same author:

http://tinyurl.com/5e89t

Luteolin apparently inhibits production of nitric oxide, which is a

mechanism several other recent investigational therapies are

pursuing (inosine/uric acid, ferulic acid).

Most supplements on the market that I've seen have a small amount of

the stuff--3 to 4 mg. I found one that has a lot--100 mg, but it's

expensive:

http:/www.lutimax.com

I am not recommending this in any way, simply passing along what

I've found in the last hour or two. Caveat emptor!