Guest guest Posted June 13, 2000 Report Share Posted June 13, 2000 Creatine is not regulated by the FDA at this time so they have no jurisdiction over whether it is safe or not. Long term effects have not been studied since it is so new to the market. EAS is one of the few companies that scientifically studies and tests the products they sell. So far creatine is safe to use by people with normal, healthy kidneys. ~Laury Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 22, 2001 Report Share Posted March 22, 2001 From what I understand, it's the creatine carb mixture that interfers with fat burning. I use the Betagen from EAS, which only has 2 grams of carb as opposed to another creatine carb product that contains 18 grams of carb in each serving. The Betagen has not slowed down my fat burning... since January 18th, I've lost 22 pounds of fat. Kathy > I know some guys that use the creatine drops before working out do the drops > have the same effect asthe powders in relation to fat burning Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 Congratulations Kathy on the great results and the hard work it took to get there! Stay strong! Kit Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 1, 2007 Report Share Posted December 1, 2007 Thanks Ed. blessings Shan In a message dated 01/12/2007 2:03:43 P.M. Eastern Standard Time, edgundy@... writes: I have been doing much more in the way of stretching and exercisingover the past month and am feeling great because of it.I have been doing some research on a supplement called CreatineMonohydrate and I came across this statement.Flexing the Heart MuscleCongestive heart failure (CHF) patients have greatly compromisedexercise tolerance. It seems logical that defects in cardiacmetabolism are the cause, but this may not be the case. Since theheart is a collection of smooth and skeletal muscles, it is likelythat impaired use of PCr in skeletal muscle also contributes toreduced endurance.21 In support of this theory, creatinesupplementation has been shown to extend exercise endurance in CHFpatients22—probably a result of creatine's ability to prolong cellularenergy production in skeletal muscle under periods of metabolicdemand, rather than a direct effect on cardiac function. In addition,studies show that muscle creatine and PCr concentrations increasefollowing supplementation in CHF patients, suggesting improvedskeletal muscle performance.I found it in this web site .And as you will see from reading the site it also is useful inreducing triglycerides and cholesterol.So... today I am going to go and get some and start using it.I wanted to bring this to everyone's attention if you may beinterested in something like this too.Ed - Moderator Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 1, 2007 Report Share Posted December 1, 2007 I’ve not done creatine, but at the recommendation of a nurse specializing in preventative health who is also a long distance runner I do have a muscle milk shake every day to replace one of my meals… According to the nurse (who happens to be my brother-in-law) and also Muscle Milk blurbs, Muscle Milk (which is modeled on Nature’s ultimate anabolic food, human mother’s milk)  helps to grow (and maintain) muscle better than even creatine. I am a former victim of congestive heart failure (all symptoms have disappeared) and stroke (pretty much back to normal once I got off statins)…  I do this in conjunction with fairly high CLA intake (1285mg 3 times a day) which is supposed to have good synergistic effect in combo with the Muscle Milk. Just another input point. Brett Breitwieser (brett@...) http://arizuma.us http://solarstation.us From: Lipitor [mailto:Lipitor ] On Behalf Of surpriseshan2@... Sent: Saturday, December 01, 2007 12:24 PM Lipitor Subject: Re: Creatine Thanks Ed. blessings Shan In a message dated 01/12/2007 2:03:43 P.M. Eastern Standard Time, edgundy@... writes: I have been doing much more in the way of stretching and exercising over the past month and am feeling great because of it. I have been doing some research on a supplement called Creatine Monohydrate and I came across this statement. Flexing the Heart Muscle Congestive heart failure (CHF) patients have greatly compromised exercise tolerance. It seems logical that defects in cardiac metabolism are the cause, but this may not be the case. Since the heart is a collection of smooth and skeletal muscles, it is likely that impaired use of PCr in skeletal muscle also contributes to reduced endurance.21 In support of this theory, creatine supplementation has been shown to extend exercise endurance in CHF patients22—probably a result of creatine's ability to prolong cellular energy production in skeletal muscle under periods of metabolic demand, rather than a direct effect on cardiac function. In addition, studies show that muscle creatine and PCr concentrations increase following supplementation in CHF patients, suggesting improved skeletal muscle performance. I found it in this web site . And as you will see from reading the site it also is useful in reducing triglycerides and cholesterol. So... today I am going to go and get some and start using it. I wanted to bring this to everyone's attention if you may be interested in something like this too. Ed - Moderator Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2007 Report Share Posted December 5, 2007 Ed, I think it would be a very good idea for everyone to read this article on Nattokinase. I don't have time to write about this wonderful enzyme and it's circulatory and heart benefits. But, I always keep a bottle in my medicine chest and I take it on a regular basis. I have found that it also seems to work very effectively on migraines- especially those related to stress or circulatory issues. Another suggestion would be to research Horsechestnut. I use it every day as well to help with my circulation ( including, brain circulation!) Here's the link to the Willner Chemist article on Nattokinase: http://www.willner.com/article.aspx?artid=88 In Wellness, Liz > > I have been doing much more in the way of stretching and exercising > over the past month and am feeling great because of it. > > I have been doing some research on a supplement called Creatine > Monohydrate and I came across this statement. > > Flexing the Heart Muscle > Congestive heart failure (CHF) patients have greatly compromised > exercise tolerance. It seems logical that defects in cardiac > metabolism are the cause, but this may not be the case. Since the > heart is a collection of smooth and skeletal muscles, it is likely > that impaired use of PCr in skeletal muscle also contributes to > reduced endurance.21 In support of this theory, creatine > supplementation has been shown to extend exercise endurance in CHF > patients22—probably a result of creatine's ability to prolong > cellular > energy production in skeletal muscle under periods of metabolic > demand, rather than a direct effect on cardiac function. In addition, > studies show that muscle creatine and PCr concentrations increase > following supplementation in CHF patients, suggesting improved > skeletal muscle performance. > > I found it in this web site > <http://www.newhope.com/nutritionsciencenews/nsn_backs/Oct_99/creatine ..c\ > fm> . > > And as you will see from reading the site it also is useful in > reducing triglycerides and cholesterol. > > So... today I am going to go and get some and start using it. > > I wanted to bring this to everyone's attention if you may be > interested in something like this too. > > Ed - Moderator > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 7, 2012 Report Share Posted February 7, 2012 I am thinking about taking a creatine supplement. Thoughts? Thank you! Lori Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 8, 2012 Report Share Posted February 8, 2012 Lori, It seems like a natural thing to replace something that breaks down in our bodies - hence people with SMA having a higher creatinine level in the blood, signifying muscle break down. Unfortunately, eating the supplement won't change that the muscles atrophy due to a problem on the cellular level. So even if you take mass amounts of the supplement, the motor neurons still will not send strong enough signals to the nerves and in turn to the muscles to stop the muscle break down. Don't mean to be a kill joy. At one point a doctor wanted me to take huge amounts of Co-Q 10, but my instincts made me ask my neurologist about it and he told me it had already been proven ineffective for us. Can't say it wouldn't make you feel better but it could put more strain on kidneys. Just my 2 cents. Let me know if you learn anything. Ellyn > > I am thinking about taking a creatine supplement. Thoughts? > > Thank you! > > > Lori > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 9, 2012 Report Share Posted February 9, 2012 Results of a clinical trial of creatine in SMA indicate it is not effective in SMA. Below is an excerpt from " Drug treatment for spinal muscular atrophy types II and III (Review) " , The Cochrane Review, 2011: *Oral creatine versus placebo (Wang 2007)* This double-blind randomised placebo-controlled trial compared oral creatine with placebo in 55 patients divided into two age groups. Of the 22 participants aged two to five years, 10 received 2 g of creatine once a day and 12 received placebo. Of the 33 participants aged 5 to 18 years, 17 received 5 g of creatine once a day and 16 received placebo.Duration of treatmentwas sixmonths with follow-up at nine months. Muscle strength for knee extension, knee flexion, and elbow flexion were measured bilaterally with the Richmond Quantitative Measurement System. Hand grip strength was measured bilaterally with handheld dynamometry. The best scores were added to obtain a total, upper body, and lower body quantitative muscle testing (QMT) score. Treatment efficacy for each age group was evaluated by intentionto- treat analysis of continuous endpoints using ANCOVA, which included the qualifying screeningmeasure as the baseline covariate, treatment group as between-subject effect, time as within-subject effect, and a subject by time interaction. The primary endpoint was the change in Gross Motor Function Measure (GMFM) from baseline. Secondary endpoints were the changes in muscle strength and pulmonary function tests (for example FVC) from baseline in children five to 18 years of age, and change in quality of life (assessed by a neuromuscular module of the parent questionnaire for the paediatric quality of life PedsQL TM) from baseline. *Discussion* Creatine may confer therapeutical benefit by increasing muscle mass and strength through its role as an energy shuttle between mitochondria and working musculature, and it could also exert neuroprotective effects (Bessman 1981; Tarnopolsky 1999; Ellis 2004). In the RCT in patients with SMA types II and III that was included in this review, there was no evidence for a therapeutic effect of oral creatine (Wong 2007). Also, in ALS two large randomised placebo-controlled trials on treatment with creatine did not demonstrate improvements in overall survival, functionalmeasurements or muscle strength (Groeneveld 2003; Shefner 2004). Two small randomised placebo-controlled trials and a Cochrane review on oral creatine for hereditary muscle diseases found muscle strength improvement in muscular dystrophies but no effect in metabolic myopathies (Walter 2000; Schneider-Gold 2003; Kley 2011). Two other Cochrane reviews on treatment in facioscapulohumeral dystrophy (Rose 2004) and Charcot-Marie-Tooth disease (Young 2008) did not show any effect of creatine. The entire article can be read here: http://dx.doi.org/10.1002/14651858.CD006282.pub3 Hope this helps. Kacper On 8 February 2012 22:24, ellynpeace@... <ellynpeace@... > wrote: > ** > > > Lori, > It seems like a natural thing to replace something that breaks down in our > bodies - hence people with SMA having a higher creatinine level in the > blood, signifying muscle break down. Unfortunately, eating the supplement > won't change that the muscles atrophy due to a problem on the cellular > level. So even if you take mass amounts of the supplement, the motor > neurons still will not send strong enough signals to the nerves and in turn > to the muscles to stop the muscle break down. > > Don't mean to be a kill joy. At one point a doctor wanted me to take huge > amounts of Co-Q 10, but my instincts made me ask my neurologist about it > and he told me it had already been proven ineffective for us. Can't say it > wouldn't make you feel better but it could put more strain on kidneys. Just > my 2 cents. Let me know if you learn anything. > > Ellyn > > > > > > I am thinking about taking a creatine supplement. Thoughts? > > > > Thank you! > > > > > > Lori > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 10, 2012 Report Share Posted February 10, 2012 Thanks very much! Lori ________________________________ From: Kacper Rucinski <kacper.rucinski@...> Sent: Thursday, February 9, 2012 4:44 AM Subject: Re: Re: Creatine Results of a clinical trial of creatine in SMA indicate it is not effective in SMA. Below is an excerpt from " Drug treatment for spinal muscular atrophy types II and III (Review) " , The Cochrane Review, 2011: *Oral creatine versus placebo (Wang 2007)* This double-blind randomised placebo-controlled trial compared oral creatine with placebo in 55 patients divided into two age groups. Of the 22 participants aged two to five years, 10 received 2 g of creatine once a day and 12 received placebo. Of the 33 participants aged 5 to 18 years, 17 received 5 g of creatine once a day and 16 received placebo.Duration of treatmentwas sixmonths with follow-up at nine months. Muscle strength for knee extension, knee flexion, and elbow flexion were measured bilaterally with the Richmond Quantitative Measurement System. Hand grip strength was measured bilaterally with handheld dynamometry. The best scores were added to obtain a total, upper body, and lower body quantitative muscle testing (QMT) score. Treatment efficacy for each age group was evaluated by intentionto- treat analysis of continuous endpoints using ANCOVA, which included the qualifying screeningmeasure as the baseline covariate, treatment group as between-subject effect, time as within-subject effect, and a subject by time interaction. The primary endpoint was the change in Gross Motor Function Measure (GMFM) from baseline. Secondary endpoints were the changes in muscle strength and pulmonary function tests (for example FVC) from baseline in children five to 18 years of age, and change in quality of life (assessed by a neuromuscular module of the parent questionnaire for the paediatric quality of life PedsQL TM) from baseline. *Discussion* Creatine may confer therapeutical benefit by increasing muscle mass and strength through its role as an energy shuttle between mitochondria and working musculature, and it could also exert neuroprotective effects (Bessman 1981; Tarnopolsky 1999; Ellis 2004). In the RCT in patients with SMA types II and III that was included in this review, there was no evidence for a therapeutic effect of oral creatine (Wong 2007). Also, in ALS two large randomised placebo-controlled trials on treatment with creatine did not demonstrate improvements in overall survival, functionalmeasurements or muscle strength (Groeneveld 2003; Shefner 2004). Two small randomised placebo-controlled trials and a Cochrane review on oral creatine for hereditary muscle diseases found muscle strength improvement in muscular dystrophies but no effect in metabolic myopathies (Walter 2000; Schneider-Gold 2003; Kley 2011). Two other Cochrane reviews on treatment in facioscapulohumeral dystrophy (Rose 2004) and Charcot-Marie-Tooth disease (Young 2008) did not show any effect of creatine. The entire article can be read here: http://dx.doi.org/10.1002/14651858.CD006282.pub3 Hope this helps. Kacper On 8 February 2012 22:24, ellynpeace@... <ellynpeace@... > wrote: > ** > > > Lori, > It seems like a natural thing to replace something that breaks down in our > bodies - hence people with SMA having a higher creatinine level in the > blood, signifying muscle break down. Unfortunately, eating the supplement > won't change that the muscles atrophy due to a problem on the cellular > level. So even if you take mass amounts of the supplement, the motor > neurons still will not send strong enough signals to the nerves and in turn > to the muscles to stop the muscle break down. > > Don't mean to be a kill joy. At one point a doctor wanted me to take huge > amounts of Co-Q 10, but my instincts made me ask my neurologist about it > and he told me it had already been proven ineffective for us. Can't say it > wouldn't make you feel better but it could put more strain on kidneys. Just > my 2 cents. Let me know if you learn anything. > > Ellyn > > > > > > I am thinking about taking a creatine supplement. Thoughts? > > > > Thank you! > > > > > > Lori > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 10, 2012 Report Share Posted February 10, 2012 Very helpful. Thank you!  Lori ________________________________ From: " ellynpeace@... " <ellynpeace@...> Sent: Wednesday, February 8, 2012 4:24 PM Subject: Re: Creatine  Lori, It seems like a natural thing to replace something that breaks down in our bodies - hence people with SMA having a higher creatinine level in the blood, signifying muscle break down. Unfortunately, eating the supplement won't change that the muscles atrophy due to a problem on the cellular level. So even if you take mass amounts of the supplement, the motor neurons still will not send strong enough signals to the nerves and in turn to the muscles to stop the muscle break down. Don't mean to be a kill joy. At one point a doctor wanted me to take huge amounts of Co-Q 10, but my instincts made me ask my neurologist about it and he told me it had already been proven ineffective for us. Can't say it wouldn't make you feel better but it could put more strain on kidneys. Just my 2 cents. Let me know if you learn anything. Ellyn > > I am thinking about taking a creatine supplement. Thoughts? > > Thank you! > >  > Lori > > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.