Re: Orapred - is refrigeration req'd????

[Guest guest]

Uh-oh, the pharmicist told me that refrigeration for Orapred was optional and I

don't refrig. mine - does this make it lose its effectiveness? I have an

unopened bottle that came from the pharmacy not refrigerated. Should I

refrigerate it after opening? We have noticed a change in our son's response to

the drug (e.g. needing more than one dose to eliminate a fever cycle) so I'm

worried that it may be due to something as simple as lack of refrigeration???

Any responses would be greatly appreciated!

Kathleen

Henry <heatherp_87@...> wrote:

Orapred now comes in 15mg/5ml. That is what we use.

Also, it is MUCH better tasting, as least to Audrey.

She doesn't fight with us half as much as she did with

the generic. It is worth the extra money. The only

down side is that it requires refrigeration.

Mother to (5) and Audrey (3 )

--- Fran Bulone <fbulone@...> wrote:

> Prednisone and Orapred ONLY comes in a dose of

> 5mg/5ml

>

> The normal dosing is 1-2mg per kg

>

> 1kg equals 2.2lb

>

> Fran

> Fran Bulone RN

> Mom to ph 7yr

> Waxhaw NC

> /

>

>

> [Non-text portions of this message have been

> removed]

>

>

__________________________________________________

[Guest guest]

According to the company info that makes Orapred it should be refrigerated and

will lose potency....

Fran

[Guest guest]

Hi Kathleen,

I've been told that it MUST be refrigerated by one

pharmicist and that it is optional by another - I

refrigerate to be safe. However, we often need to

give a second dose dispite this. I would love to know

what happens to it when it is not refrigerated.

Mom to (5) and Audrey (3 )

--- Kathleen Cunningham <kjbcunningham@...>

wrote:

> Uh-oh, the pharmicist told me that refrigeration for

> Orapred was optional and I don't refrig. mine - does

> this make it lose its effectiveness? I have an

> unopened bottle that came from the pharmacy not

> refrigerated. Should I refrigerate it after

> opening? We have noticed a change in our son's

> response to the drug (e.g. needing more than one

> dose to eliminate a fever cycle) so I'm worried that

> it may be due to something as simple as lack of

> refrigeration???

>

> Any responses would be greatly appreciated!

> Kathleen

>

> Henry <heatherp_87@...> wrote:

> Orapred now comes in 15mg/5ml. That is

> what we use.

> Also, it is MUCH better tasting, as least to Audrey.

>

> She doesn't fight with us half as much as she did

> with

> the generic. It is worth the extra money. The only

> down side is that it requires refrigeration.

>

>

> Mother to (5) and Audrey (3 )

>

> --- Fran Bulone <fbulone@...> wrote:

>

> > Prednisone and Orapred ONLY comes in a dose of

> > 5mg/5ml

> >

> > The normal dosing is 1-2mg per kg

> >

> > 1kg equals 2.2lb

> >

> > Fran

> > Fran Bulone RN

> > Mom to ph 7yr

> > Waxhaw NC

> > /

> >

> >

> > [Non-text portions of this message have been

> > removed]

> >

> >

>

> __________________________________________________

>

[Guest guest]

Hi Again

Just went to the orapred.com site and checked out the info packet pdf file. It

states the medication must be refrigerated.

I went ahead and wrote to the company to get more information for all of you

questioning the info packet information and getting different advise from

pharmacists.

Will update as soon as I get more info.

Fran

Fran Bulone RN

Mom to ph 7yr

Waxhaw NC

/

[Guest guest]

We use Orapred for our son.

And for the first few years, I had no idea it had to be kept in the

refrigerator. It was not labeled on the bottle, the doctor did not

tell me to and the pharmacist did not tell me to. So I kept it in

the medicine cabinet.

Also it is interesting to note that one bottle lasted me over 2

years, so the expiration date had come and gone. And according to

several doctors, (including the infectious disease specialist we

saw), Orapred is effective for long after a year. If it looses any

effectiveness, it is very very minimal.

Anyway, despite being expired and not being refrigerated, my son's

fever always " vanished " within one hour of taking it.

I do keep it in the refrigerator now, but I don't feel uncomforable

about traveling with it and keeping it in a hotel room for a few

days while on vacation unrefrigerated. Then it goes back into the

fridge when we get home.

So in our experience not keeping it in the fridge did not change the

effectiveness of the Orapred.

Hope this helps. in Tampa, Mom to Jonah 5 years old.

> >

> > > Prednisone and Orapred ONLY comes in a dose of

> > > 5mg/5ml

> > >

> > > The normal dosing is 1-2mg per kg

> > >

> > > 1kg equals 2.2lb

> > >

> > > Fran

> > > Fran Bulone RN

> > > Mom to ph 7yr

> > > Waxhaw NC

> > > /

> > >

> > >

> > > [Non-text portions of this message have been

> > > removed]

> > >

> > >

> >

> > __________________________________________________

> >

[Guest guest]

FYI

We have used Orapred not for , but for many other things in all three of

our children and our doc has always said it does not have to be refrigerated but

it does taste alittle bit better if it is. I'm hoping to convince my

pediatrician after Ryleigh's next episode to listen to th ID Doc and that she

does have and to start using it for the episodes though.

Hope this helps, Mom to Ryleigh 3 in Nov.

Re: Orapred - is refrigeration req'd????

We use Orapred for our son.

And for the first few years, I had no idea it had to be kept in the

refrigerator. It was not labeled on the bottle, the doctor did not

tell me to and the pharmacist did not tell me to. So I kept it in

the medicine cabinet.

Also it is interesting to note that one bottle lasted me over 2

years, so the expiration date had come and gone. And according to

several doctors, (including the infectious disease specialist we

saw), Orapred is effective for long after a year. If it looses any

effectiveness, it is very very minimal.

Anyway, despite being expired and not being refrigerated, my son's

fever always " vanished " within one hour of taking it.

I do keep it in the refrigerator now, but I don't feel uncomforable

about traveling with it and keeping it in a hotel room for a few

days while on vacation unrefrigerated. Then it goes back into the

fridge when we get home.

So in our experience not keeping it in the fridge did not change the

effectiveness of the Orapred.

Hope this helps. in Tampa, Mom to Jonah 5 years old.

> >

> > > Prednisone and Orapred ONLY comes in a dose of

> > > 5mg/5ml

> > >

> > > The normal dosing is 1-2mg per kg

> > >

> > > 1kg equals 2.2lb

> > >

> > > Fran

> > > Fran Bulone RN

> > > Mom to ph 7yr

> > > Waxhaw NC

> > > /

> > >

> > >

> > > [Non-text portions of this message have been

> > > removed]

> > >

> > >

> >

> > __________________________________________________

> >

[Guest guest]

Hi Fran, I am assuming this would be the same info for prednisolone. Correct?

Patti mother of Brady 7

Fran Bulone <fbulone@...> wrote:

Hi Again

Just went to the orapred.com site and checked out the info packet pdf file. It

states the medication must be refrigerated.

I went ahead and wrote to the company to get more information for all of you

questioning the info packet information and getting different advise from

pharmacists.

Will update as soon as I get more info.

Fran

Fran Bulone RN

Mom to ph 7yr

Waxhaw NC

/

[Guest guest]

>>>Hi Fran, I am assuming this would be the same info for prednisolone.>>>

No... just the Orapred.

Fran

Fran Bulone RN

Mom to ph 7yr

Waxhaw NC

/

[Guest guest]

As a Pharmacist I will tell you what I think.

We must keep Orapred under refrigeration to guarantee it will be stable

through the manufacturers expiration date. Especially since we may have the

bottle around for a year or more.

Often we dispense just small amounts--enough for 1 course of therapy.If

left unrefrigerated, it will not suddenly deteriorate and stop working--that

takes time to happen. So if it does stay unrefrigerated for a short time--it

should still be OK.

However--I always tell everyone to refrigerate it. I never know what

conditions patients will keep it. If I say it is ok to keep out for a day or

so---I

never know if that person happens to have it in a extremely hot car on a 100

degree day--which would not be ideal for any drug , let alone one that needs

refrigeration!

Mom to -9 -7 () and -5