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Both of my boys have neutropenia (due to having Shwachman-Diamond Syndrome)

and my youngest has used Neupogen (G-CSF) and GM-CSF before. We do not use

it on a regular schedule— we use it as needed, before surgeries, etc….. to

boost their WBC. If you go to the Amgen website, you can view a PDF of the

physician’s insert. We live in North Carolina, but are followed by the

Bone Marrow Failure clinic at CCHMC in Cincinnati & also see immunology

there. We’ll be up there in February for the boys BMBs and follow-up

appointments.

Peace be with you,

Pattie

God does not intervene to change the circumstances of our life; what He does

do, with the most compassionate faithfulness, is enable us to make those

circumstances fruitful. Death remains death, but it is also a new life: pain

accepted from His hands purifies, transforms, redeems. God is what happens

to us; His presence makes everything potential for growth in love and

goodness. Yes, let Him make us Holy. ~Sister Beckett

_____

From: [mailto: ] On Behalf Of

Sent: Sunday, January 06, 2008 6:05 PM

Subject: Neupogen

Does anyone here have any experience with neupogen therapy? It has

been recommended by several doctors to start Meredith and will be

discussing it in Cincinnati this week. I'd like a real-life

experience instead of just the drug info.

Thanks!

Mom to , 5 GSD and PIDD

Meredith, 3 GSD and PIDD

and , 8 healthy

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Thanks Pattie! I had read the info on the Amgen website but was wanting

personal experiences, too. Thanks for yours. How do you determine if your

boys need it? Neutropenia is common in one form of GSD and those patients

use it daily for the rest of their lives once they reach the point of

needing to start. I had understood that this would most likely be the case

with Meredith (and possibly ) so I’m curious about using it

temporarily.

Also, does taking GCSF raise WBC in addition to the ANC? WBC are also low

in them and didn’t realize that would improve with neupogen but I guess

since neutrophils are white cells, that makes sense. I just hadn’t put that

together.

Mom to , 5 GSD, PIDD

Meredith, 2 GSD, PIDD

, 8 healthy

Huntsville, AL

www.caringbridge.com/visit/mhobbs

_____

From: [mailto: ] On Behalf Of

Pattie Curran

Sent: Sunday, January 06, 2008 5:40 PM

Subject: RE: Neupogen

Both of my boys have neutropenia (due to having Shwachman-Diamond Syndrome)

and my youngest has used Neupogen (G-CSF) and GM-CSF before. We do not use

it on a regular schedule— we use it as needed, before surgeries, etc….. to

boost their WBC. If you go to the Amgen website, you can view a PDF of the

physician’s insert. We live in North Carolina, but are followed by the

Bone Marrow Failure clinic at CCHMC in Cincinnati & also see immunology

there. We’ll be up there in February for the boys BMBs and follow-up

appointments.

Peace be with you,

Pattie

God does not intervene to change the circumstances of our life; what He does

do, with the most compassionate faithfulness, is enable us to make those

circumstances fruitful. Death remains death, but it is also a new life: pain

accepted from His hands purifies, transforms, redeems. God is what happens

to us; His presence makes everything potential for growth in love and

goodness. Yes, let Him make us Holy. ~Sister Beckett

_____

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On Behalf

Of

Sent: Sunday, January 06, 2008 6:05 PM

groups (DOT) <mailto:%40> com

Subject: Neupogen

Does anyone here have any experience with neupogen therapy? It has

been recommended by several doctors to start Meredith and will be

discussing it in Cincinnati this week. I'd like a real-life

experience instead of just the drug info.

Thanks!

Mom to , 5 GSD and PIDD

Meredith, 3 GSD and PIDD

and , 8 healthy

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  • 8 months later...

Hi gang,

I am half way through treatment. I feel run down at times. The doc just put me on a new med shot two times per week, neupogen. it is to help make more white blood cells. Has anyone taken this med? They gave me one shot yesterday and i don't feel much better. I guess it take a little while before it works. Hope every one is doing well in tx, and all other stages.

Hoku

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