Re: Andy on why Time-Release ALA is not safe

[Guest guest]

Thank you for clarifying this,

Eileen

>

> Different things are absorbed at different points along the GI tract. All

> the chelators (DMPS, DMSA and ALA) are absorbed very early in the GI tract

> and not later on. Basically they are the types of things that are only

> going to be absorbed under acidic conditions so they're absorbed in the

> stomach and perhaps jeujunum. No place else.

>

> Thus it doesn't matter how good or bad the time release is - I'm sure the

> earlier formulations were fine too as far as releasing ALA evenly over 8,

> 12 or 24 hours as advertized.

>

> Direct measurements of blood ALA levels versus time in human subjects

> taking both immediate release ALA and 8 hour time release ALA showed no

> difference at all. They both cleared from the bloodstream equally fast.

This

> data was developed by one of the commercial manufacturers of time release

ALA,

> if anything they had motivation to show it worked. Their own data clearly

> showed it didn't.

>

> On the other hand, the measured dissolution of their time release

> formulation in a lab model of digestive juice really did show it releasing

over

> time.

>

> There really is no solution to this absorption problem other than give the

> ALA every 3-4 hours, regardless of whether it is an immediate release or

> time release formulation

>

> Andy

>

[Guest guest]

The adverse effects of large doses of ALA have been documented to be a bad idea.

Refer to Dan! Consensus Paper of 2001, where ALA was recommended in larger doses

than in AC Chelation, (where a very small dose used for its ability to assist

DMSA and is quite a different matter.)

Revisiting the subject of ALA in 2005, The Dan Consensus Paper concluded that

ALA was more trouble than it was worth, for all its powerful anti-oxidative

powers, in autism. Causes intestinal yeast and fungi which is out of all

proportion to any benefit and counterproductive.

They concluded that most anti-yeast measures used such as Capryllic acid,

herbals even Sacchromyces Boulardi had no effect in slowing down yeast infection

and in many cases it becomes systemic.

Does not get my vote in any form. In any case, what if the kids react to the

substance that makes it time-release for example? Our kids are so sensitive to

stuff. If it is one that relies on stomach acids to dissolve it, it wouldn't

work in this house not that we are having it anyway. Lots of our kids have low

stomach acid which makes them prone to bugs anyway, I need what stomach acid is

there to help immune system deal with bugs, without a time release gobbling it

up, creating problems as well as a large dose of a yeast promoter

No thank you

E x

> >

> > Different things are absorbed at different points along the GI tract. All

> > the chelators (DMPS, DMSA and ALA) are absorbed very early in the GI tract

> > and not later on. Basically they are the types of things that are only

> > going to be absorbed under acidic conditions so they're absorbed in the

> > stomach and perhaps jeujunum. No place else.

> >

> > Thus it doesn't matter how good or bad the time release is - I'm sure the

> > earlier formulations were fine too as far as releasing ALA evenly over 8,

> > 12 or 24 hours as advertized.

> >

> > Direct measurements of blood ALA levels versus time in human subjects

> > taking both immediate release ALA and 8 hour time release ALA showed no

> > difference at all. They both cleared from the bloodstream equally fast.

This

> > data was developed by one of the commercial manufacturers of time release

ALA,

> > if anything they had motivation to show it worked. Their own data clearly

> > showed it didn't.

> >

> > On the other hand, the measured dissolution of their time release

> > formulation in a lab model of digestive juice really did show it releasing

over

> > time.

> >

> > There really is no solution to this absorption problem other than give the

> > ALA every 3-4 hours, regardless of whether it is an immediate release or

> > time release formulation

> >

> > Andy

> >

>