Guest guest Posted January 15, 2008 Report Share Posted January 15, 2008 Hi everyone, I'm at a loss as to what to think of these results. My sons ped., upon my request had a second hematologist read the results and no one seems concerned about it. The ID doctor brushed it off but said that he could be possibly anemic. His tests for anemia came back negative. So my crazy question of the day... how do I know that my son was born with a spleen? I've been reading about how the spleen is a big contributer to the immune system. And the only reason I even wonder this is because the results read " post splenectomy? " as a possible conclusion. So I am posting the exact text from the lab report below. I know that no one can give me medical advice, but just your opinion. And that is what I'm seeking. Should I be asking to see a rhuematologist at his next fever? I consider ourselves lucky in that Renan fevers approx. every 6-8 weeks. He does complain of tummy aches and joint pain but no mouth sores or throat irritations that he's mentioned. Thanks as always! I truly appreciate all of your posts. Your courage is what keeps me researching. -- The report reads (according to his ped.) that he is anemic but he's not anemic. So at that point he just brushed it off. Here is what the review says: " Review of the peripheral smear demonstrates RBC variation, including echinocytes, some cells suggestive of acanthocytes, occasional tear drop shaped cells and rare smaller fragments. WBC's include occasional cells with nuclear hyposegmentation. Occasional enlarged platelets are noted. Clinical correlation is required. If there is no clinical explanation (?postsplenectomy?) hemoglobin electrophoresis could be considered, however the hemoglobin is within the normal range. " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 wow i myself have no idea what that means but could you please keep us posted on what you find out. ask the dr. to explain it all to you. try not to worry until they explain. char ************** Start the year off right. Easy ways to stay in shape. http://body.aol.com/fitness/winter-exercise?NCID=aolcmp00300000002489 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 wow i myself have no idea what that means but could you please keep us posted on what you find out. ask the dr. to explain it all to you. try not to worry until they explain. char ************** Start the year off right. Easy ways to stay in shape. http://body.aol.com/fitness/winter-exercise?NCID=aolcmp00300000002489 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 wow i myself have no idea what that means but could you please keep us posted on what you find out. ask the dr. to explain it all to you. try not to worry until they explain. char ************** Start the year off right. Easy ways to stay in shape. http://body.aol.com/fitness/winter-exercise?NCID=aolcmp00300000002489 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 Hey , The reason why your report mentions something about post-splenectomy is because the spleen is essentially the vacuum-cleaner of damaged and dead cells within the blood, and because of the differential seeing acanthocytes, tear-drop cells, and fragmented cells, this suggests that the spleen is either not there or is not working properly, as these cells are not seen in a normal person's blood at an appreciable amount. My curiosity got the best of me, and I looked it up to see if some people are born without spleens. It can happen, but it is very rare. Another problem is where the spleen is present, but not functioning correctly. You can easily determine if it is there or not by having an ultrasound done. Yes, the spleen does help with some immune functions, and it also functions as a storage of platelets. When your child was still a fetus, it functioned as part of the hematopoesis system, and made red cells, whereas in you and me (and your child, as well), hematopoesis occurs in the marrow. If it is still functioning hematopoetically, then there runs the risk of hemoglobinopathies, which may be one of the reasons why the doctor suggests a hemoglobin electrophoresis. And finally, if your insurance pays well, you may want another smear made from new venous blood and read by a different hematologist, because all of the anomolies seen in the red cells can be artificially made because of the cells sitting in the tube for too long (echinocytes), and the smear on the slide being poorly made (tear-drops and fragmented from probably too much pressure). Don't take my word as some gospel. I do work in a hospital lab as a lab technician, and spend 99% of my work-days in hematology, but maybe these suggestions can give you some ideas! Good luck! Liz Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 Hey , The reason why your report mentions something about post-splenectomy is because the spleen is essentially the vacuum-cleaner of damaged and dead cells within the blood, and because of the differential seeing acanthocytes, tear-drop cells, and fragmented cells, this suggests that the spleen is either not there or is not working properly, as these cells are not seen in a normal person's blood at an appreciable amount. My curiosity got the best of me, and I looked it up to see if some people are born without spleens. It can happen, but it is very rare. Another problem is where the spleen is present, but not functioning correctly. You can easily determine if it is there or not by having an ultrasound done. Yes, the spleen does help with some immune functions, and it also functions as a storage of platelets. When your child was still a fetus, it functioned as part of the hematopoesis system, and made red cells, whereas in you and me (and your child, as well), hematopoesis occurs in the marrow. If it is still functioning hematopoetically, then there runs the risk of hemoglobinopathies, which may be one of the reasons why the doctor suggests a hemoglobin electrophoresis. And finally, if your insurance pays well, you may want another smear made from new venous blood and read by a different hematologist, because all of the anomolies seen in the red cells can be artificially made because of the cells sitting in the tube for too long (echinocytes), and the smear on the slide being poorly made (tear-drops and fragmented from probably too much pressure). Don't take my word as some gospel. I do work in a hospital lab as a lab technician, and spend 99% of my work-days in hematology, but maybe these suggestions can give you some ideas! Good luck! Liz Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 16, 2008 Report Share Posted January 16, 2008 Hey , The reason why your report mentions something about post-splenectomy is because the spleen is essentially the vacuum-cleaner of damaged and dead cells within the blood, and because of the differential seeing acanthocytes, tear-drop cells, and fragmented cells, this suggests that the spleen is either not there or is not working properly, as these cells are not seen in a normal person's blood at an appreciable amount. My curiosity got the best of me, and I looked it up to see if some people are born without spleens. It can happen, but it is very rare. Another problem is where the spleen is present, but not functioning correctly. You can easily determine if it is there or not by having an ultrasound done. Yes, the spleen does help with some immune functions, and it also functions as a storage of platelets. When your child was still a fetus, it functioned as part of the hematopoesis system, and made red cells, whereas in you and me (and your child, as well), hematopoesis occurs in the marrow. If it is still functioning hematopoetically, then there runs the risk of hemoglobinopathies, which may be one of the reasons why the doctor suggests a hemoglobin electrophoresis. And finally, if your insurance pays well, you may want another smear made from new venous blood and read by a different hematologist, because all of the anomolies seen in the red cells can be artificially made because of the cells sitting in the tube for too long (echinocytes), and the smear on the slide being poorly made (tear-drops and fragmented from probably too much pressure). Don't take my word as some gospel. I do work in a hospital lab as a lab technician, and spend 99% of my work-days in hematology, but maybe these suggestions can give you some ideas! Good luck! Liz Quote Link to comment Share on other sites More sharing options...
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