Re: Spiro or Epler (effect on Cortisol & Estrogen)

[Guest guest]

I've posted this before but added the last two items. If you are concerned

about depression, Cortisol or Estrogen and Spironolctone effect it might be

worth your read. I am awaiting an opinion from my Psychiatrists and will share

when I hear from her.

Source: http://archpsyc.ama-assn.org/cgi/content/full/60/1/24

Mineralocorticoid Receptor Function in Major Depression

A. Young, MD; F. , MD; Virginia -Weinberg, MS, RN;

Stanley J. , MD, PhD; Huda Akil, PhD

Arch Gen Psychiatry. 2003;60:24-28.

Graph from above article, A picture is worth 1000 words! See this:

Source: http://archpsyc.ama-assn.org/cgi/content-nw/full/60/1/24/FIGYOA20492F1

Two new items on the subject at hand:

Source: http://www.indepression.com/cortisol-and-depression.html

Cortisol

It is found that the people who are clinically depressed, about half of them

have the excess of cortisol hormone.

Source: http://www.indepression.com/estrogen-and-depression.html

Estrogen and Depression

High levels of estrogen increases brain's response to stress which is

responsible that women are more vulnerable to mental illnesses such as

depression and post-traumatic stress disorder (PTSD) than men.

Is it time to stop affecting androgen when treating PA?

- 65 yo super ob., fastidious male - 12mm X 13mm rt. a.adnoma with

previous rt. flank pain. Treating with DASH. Stats w/o meds = BP 175/90 HR 59

BS 125. D/C Spironolactone 12/20/2011 due to adverse SX.

Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, Gynecomastia, MDD

and PTSD.

Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg aspirin and

Metformin 2000MG. Started washing Spironolactone 12/20/11 to prepare for AVS.

> > > > > > > > > > > > >

> > > > > > > > > > > > > > So, from what I see on the internet...Epler is

expensive, Spiro is

> > > > > > > > > > > > > > che

>