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Re: PA DX by NP-59

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Primary aldosteronism (PA) may be missed in patients with chronic kidney

disease (CKD), because CKD may disturb the renin-angiotensin-aldosterone system. Adrenal vein sampling has increased risks in patients with CKD. We report the case of a 58-year-old man with CKD and suspected PA. Left adrenal aldosteronism was diagnosed by NP-59 SPECT/CT. Left adrenalectomy demonstrated adrenocortical nodular hyperplasia. Plasma aldosterone normalized and blood pressure stabilized after surgery. NP-59 SPECT/CT may be a helpful

diagnostic tool for detecting and lateralizing PA in CKD patients.>> > 1.> > Diagnosis of Primary Aldosteronism in Chronic Kidney Disease by I-131 NP-59 SPECT/CT Imaging. <http://www.ncbi.nlm.nih.gov/pubmed/22228361> > > > Chen YC, Su YC, Chiu JS, Tseng CE.> > > Clin Nucl Med. 2012 Feb;37(2):e30-e32.> > > PMID: 22228361 [PubMed - as supplied by publisher]> > > Related citations <http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed & cmd=link & linkname=pubmed_pubmed & uid=22228361>>

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Was renin low and aldo high? CE Grim MDOn Jan 14, 2012, at 10:30 AM, Study Circle wrote: Primary aldosteronism (PA) may be missed in patients with chronic kidney disease (CKD), because CKD may disturb the renin-angiotensin-aldosterone system. Adrenal vein sampling has increased risks in patients with CKD. We report the case of a 58-year-old man with CKD and suspected PA. Left adrenal aldosteronism was diagnosed by NP-59 SPECT/CT. Left adrenalectomy demonstrated adrenocortical nodular hyperplasia. Plasma aldosterone normalized and blood pressure stabilized after surgery. NP-59 SPECT/CT may be a helpful diagnostic tool for detecting and lateralizing PA in CKD patients.>> > 1.> > Diagnosis of Primary Aldosteronism in Chronic Kidney Disease by I-131 NP-59 SPECT/CT Imaging. <http://www.ncbi.nlm.nih.gov/pubmed/22228361> > > > Chen YC, Su YC, Chiu JS, Tseng CE.> > > Clin Nucl Med. 2012 Feb;37(2):e30-e32.> > > PMID: 22228361 [PubMed - as supplied by publisher]> > > Related citations <http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed & cmd=link & linkname=pubmed_pubmed & uid=22228361>>

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Chances of long term cure with documented hyperplasia in one gland is low.Will wait for long term followup.Did pt get to CRD due to renal toxicity from contrast use for CE etc?? On Jan 14, 2012, at 10:28 AM, StudyCircle wrote: 1.Diagnosis of Primary Aldosteronism in Chronic Kidney Disease by I-131 NP-59 SPECT/CT Imaging.Chen YC, Su YC, Chiu JS, Tseng CE.Clin Nucl Med. 2012 Feb;37(2):e30-e32.PMID: 22228361 [PubMed - as supplied by publisher]Related citations

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