Guest guest Posted March 4, 2012 Report Share Posted March 4, 2012 I'd recommend that you tell the nephologist that you are taking Yasmin, and that you are aware that the progestin in it (drospirenone) is a mineralcorticoid blocker(as is spironolactone), and that you are concerned that this is skewing your test results. One would think that doctors pay attention to the forms you fill out that include the meds you are on, but sometimes they don't know what something is (or they confuse it with something else, or just plain don't know what it is) so it really is good to address these things from the start. I did a quick PubMed search for " drospirenone spironolactone " and got some interesting results, most notably: http://www.ncbi.nlm.nih.gov/pubmed/22147655 Which states that " false positive aldosterone-renin ratios can occur... while taking an oral ethynylestradiol/drospirenone... contraceptive, but only if calculated using direct renin concentration and not plasma renin activity. " > > > So are you saying that if I were on a progestin-only pill I would feel > better or worse? > > I'm saying that your testing would be more accurate. Estrogen can raise > BP, and the progestin in Yazmin or Yaz can elevate potassium (so much > that it has killed people as a result; I've read there are pending > lawsuits about this.) > > As for whether you'd feel better or worse on a POP - my guess would be > the same, or worse. The progestin in Yazmin acts somewhat like > spironolactone, so it's probably lowering your BP somewhat and raising > your K somewhat. If anything, this would make you feel better, but would > give you false BP and K readings. > > The main takeaway here is that if testing for PA isn't considered > accurate when done while on spironolactone, it shouldn't be considered > accurate when done on Yazmin. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 4, 2012 Report Share Posted March 4, 2012 There are a few others (some are generics for Yasmin): YAZ, Beyaz, Safyral, Ocella, Gianvi, Zarah, Loryna, Syeda, and Vestura. > > > > > So are you saying that if I were on a progestin-only pill I would feel > > better or worse? > > > > I'm saying that your testing would be more accurate. Estrogen can raise > > BP, and the progestin in Yazmin or Yaz can elevate potassium (so much > > that it has killed people as a result; I've read there are pending > > lawsuits about this.) > > > > As for whether you'd feel better or worse on a POP - my guess would be > > the same, or worse. The progestin in Yazmin acts somewhat like > > spironolactone, so it's probably lowering your BP somewhat and raising > > your K somewhat. If anything, this would make you feel better, but would > > give you false BP and K readings. > > > > The main takeaway here is that if testing for PA isn't considered > > accurate when done while on spironolactone, it shouldn't be considered > > accurate when done on Yazmin. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 8, 2012 Report Share Posted March 8, 2012 Isn't it wonderful to be treated by a professional who knows how treat you? Maybe the best part is you didn't hve to train him! ;>) I did some research on salt sensitivity once and one of the points/conclusions was that low birth weight was often a contributing factor. Dash, Dash, Dash and watch that NA! > >> > >> > So are you saying that if I were on a progestin-only pill I would feel > >> better or worse? > >> > >> I'm saying that your testing would be more accurate. Estrogen can raise > >> BP, and the progestin in Yazmin or Yaz can elevate potassium (so much > >> that it has killed people as a result; I've read there are pending > >> lawsuits about this.) > >> > >> As for whether you'd feel better or worse on a POP - my guess would be > >> the same, or worse. The progestin in Yazmin acts somewhat like > >> spironolactone, so it's probably lowering your BP somewhat and raising > >> your K somewhat. If anything, this would make you feel better, but would > >> give you false BP and K readings. > >> > >> The main takeaway here is that if testing for PA isn't considered > >> accurate when done while on spironolactone, it shouldn't be considered > >> accurate when done on Yazmin. > >> > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2012 Report Share Posted March 25, 2012 Thanks for this thread! I am newly diagnosed and take generic Yasmin. I have normal BP and pottasium levels which the Dr's find confusing. I am going to tell my endo this info and maybe we can retest to see if the tests I have had to date are accurate - Thanks! > > I have been off of Yasmin BCP's for 2 weeks now and have been given the go-ahead > from my Nephrologist to redo my blood work and 24 hour urine. When I went to the > Lab to get my 24 hour urine container and arrange the blood work, the lab > technician there said they would would be able to measure > volume/creatinine/creatinine clearance and cortisol in the 24 hour urine, but > did not have the right chemical to measure aldosterone in urine. She also said > they would be able to blood work requested which is serum creatinine, > aldosterone and renin after laying down for 30 minutes. > > Since I haven't been able to get a hold of my Nephrologist, I thought I'd ask > here if it is possible for anything to be determined without the aldosterone > measured in the urine. I'm pretty sure the answer is no, but was just curious > what other feedback anyone could give me. Thanks in advance!!! > > > 27 y/o , 112 lb at 5'6, female with 4+ year history of hypertension (Avg > 140/95). Taken off all bp meds because of resistance to them. Have recently been > taken off of Yasmin BCPs to have all tests redone. First Aldo level taken this > past June was 88 ng/dl. Taken again in July and was down to 18.8 ng/dl. Then > back up to 42 ng/dl. K- 4.5, NA- 138, renin- 0.65. Most recently aldo was taken > with 24 hour urine. Aldo was 82 ng/dL. No known underlying illnesses other than > a mild aortic murmur. Symptoms - shortness of breath, heart palpitations, > nocturia 2+ times per night, fatigue/weakness. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2012 Report Share Posted March 25, 2012 U want them to measure Na and K in urine so. For do they may need a jug thT has acid in it. Not all labs keep this jug in stock. Be careful what u stick in the jug tho May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn Mar 25, 2012, at 17:57, marseachelle02 <marseachelle02@...> wrote: I have been off of Yasmin BCP's for 2 weeks now and have been given the go-ahead from my Nephrologist to redo my blood work and 24 hour urine. When I went to the Lab to get my 24 hour urine container and arrange the blood work, the lab technician there said they would would be able to measure volume/creatinine/creatinine clearance and cortisol in the 24 hour urine, but did not have the right chemical to measure aldosterone in urine. She also said they would be able to blood work requested which is serum creatinine, aldosterone and renin after laying down for 30 minutes. Since I haven't been able to get a hold of my Nephrologist, I thought I'd ask here if it is possible for anything to be determined without the aldosterone measured in the urine. I'm pretty sure the answer is no, but was just curious what other feedback anyone could give me. Thanks in advance!!! 27 y/o , 112 lb at 5'6, female with 4+ year history of hypertension (Avg 140/95). Taken off all bp meds because of resistance to them. Have recently been taken off of Yasmin BCPs to have all tests redone. First Aldo level taken this past June was 88 ng/dl. Taken again in July and was down to 18.8 ng/dl. Then back up to 42 ng/dl. K- 4.5, NA- 138, renin- 0.65. Most recently aldo was taken with 24 hour urine. Aldo was 82 ng/dL. No known underlying illnesses other than a mild aortic murmur. Symptoms - shortness of breath, heart palpitations, nocturia 2+ times per night, fatigue/weakness. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2012 Report Share Posted March 25, 2012 Hi Doctor, Thanks for inquiring. I was diagnosed with a right adrenal adenoma 5 years ago but it was thought to be non-functioning and non-malignant. I recently went to the Dr. upon getting health insurance because I had been experiencing ongoing severe fatigue, major blood sugar fluctuations,rapid weight gain, and night sweats/excess daytime sweating. My GP reconfirmed previously diagnosed hypoglycemia and found that I had 3x the max level of aldosterone. I have normal to low BP and no potassium or electrolyte abnormalities which is good (but as the thread indicated may be due to by Yasmin use). I was referred to an endo who has confirmed that I have excess aldosterone and feels that it must be an aldosteronoma. I am following up with her about next steps in a couple weeks. I am doing urine labs and rescanning in the interim. I am hoping to utilize this group to learn more and support others. Thanks! > > > > > > I have been off of Yasmin BCP's for 2 weeks now and have been given the go-ahead > > > from my Nephrologist to redo my blood work and 24 hour urine. When I went to the > > > Lab to get my 24 hour urine container and arrange the blood work, the lab > > > technician there said they would would be able to measure > > > volume/creatinine/creatinine clearance and cortisol in the 24 hour urine, but > > > did not have the right chemical to measure aldosterone in urine. She also said > > > they would be able to blood work requested which is serum creatinine, > > > aldosterone and renin after laying down for 30 minutes. > > > > > > Since I haven't been able to get a hold of my Nephrologist, I thought I'd ask > > > here if it is possible for anything to be determined without the aldosterone > > > measured in the urine. I'm pretty sure the answer is no, but was just curious > > > what other feedback anyone could give me. Thanks in advance!!! > > > > > > > > > 27 y/o , 112 lb at 5'6, female with 4+ year history of hypertension (Avg > > > 140/95). Taken off all bp meds because of resistance to them. Have recently been > > > taken off of Yasmin BCPs to have all tests redone. First Aldo level taken this > > > past June was 88 ng/dl. Taken again in July and was down to 18.8 ng/dl. Then > > > back up to 42 ng/dl. K- 4.5, NA- 138, renin- 0.65. Most recently aldo was taken > > > with 24 hour urine. Aldo was 82 ng/dL. No known underlying illnesses other than > > > a mild aortic murmur. Symptoms - shortness of breath, heart palpitations, > > > nocturia 2+ times per night, fatigue/weakness. > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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