Re: BCPs

[Guest guest]

I'd recommend that you tell the nephologist that you are taking Yasmin, and that

you are aware that the progestin in it (drospirenone) is a mineralcorticoid

blocker(as is spironolactone), and that you are concerned that this is skewing

your test results. One would think that doctors pay attention to the forms you

fill out that include the meds you are on, but sometimes they don't know what

something is (or they confuse it with something else, or just plain don't know

what it is) so it really is good to address these things from the start.

I did a quick PubMed search for " drospirenone spironolactone " and got some

interesting results, most notably:

http://www.ncbi.nlm.nih.gov/pubmed/22147655

Which states that " false positive aldosterone-renin ratios can occur... while

taking an oral ethynylestradiol/drospirenone... contraceptive, but only if

calculated using direct renin concentration and not plasma renin activity. "

>

> > So are you saying that if I were on a progestin-only pill I would feel

> better or worse?

>

> I'm saying that your testing would be more accurate. Estrogen can raise

> BP, and the progestin in Yazmin or Yaz can elevate potassium (so much

> that it has killed people as a result; I've read there are pending

> lawsuits about this.)

>

> As for whether you'd feel better or worse on a POP - my guess would be

> the same, or worse. The progestin in Yazmin acts somewhat like

> spironolactone, so it's probably lowering your BP somewhat and raising

> your K somewhat. If anything, this would make you feel better, but would

> give you false BP and K readings.

>

> The main takeaway here is that if testing for PA isn't considered

> accurate when done while on spironolactone, it shouldn't be considered

> accurate when done on Yazmin.

>