Re: Agent Orange and Man Boobs

[Guest guest]

During my last visit with the nephrologist who doesn't like working with NIH,

she prescribed me Spiro. When I asked her why Spiro over Epler, since Epler is

selective, etc., she said, yeah, but women like Spiro! She went on about how it

improves women's skin, adult onset acne issues and how women give her glowing

feedback about it's side effects. She assured me that I would like it, even

though I protested, saying that I don't have acne, so maybe I wouldn't be in the

category for women who want that side effect? She encouraged me to try it,

since it's older, and it also helps with hirsitism...(sp?)...gets rid of those

nasty hairs we women past menopause have to deal with. I said, doesn't it also

cause women to have sore, more dense breasts? And maybe I want to avoid that

since my Mom had fibrocystic dense breasts? Well, she said, if you don't like

it, we can switch you to Epler, but she really thought I'd like it, and wrote

the script for it. Just thought you might get a kick out of that. After I get

evaluated at NIH, if they suggest Epler or Spiro, I hope the conversation will

be based on research and possibly the results of good labs and valid tests and

even possibly, me, as an idividual. Wouldn't that be great?

>

> Does Agent Orange cause gyneocomastia? Maybe if you add a small dose of

Spironolactone!

>

> Source: http://www.ncbi.nlm.nih.gov/pubmed/17107848

>

> Serum dioxin, testosterone, and subsequent risk of benign prostatic

hyperplasia: a prospective cohort study of Air Force veterans.

>

> Gupta A, Ketchum N, Roehrborn CG, Schecter A, Aragaki CC, Michalek JE.

> Source

> The University of Texas School of Public Health, Regional Campus at Dallas,

Dallas, Texas 75390-9110, USA. amit.gupta@...

> Abstract

>

> BACKGROUND:

> Operation Ranch Hand veterans were involved in spraying herbicides, including

Agent Orange, during the Vietnam War in 1962-1971; Agent Orange was contaminated

with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). It has been hypothesized that

dioxins may be partially responsible for an increase of male reproductive tract

disorders such as testicular cancer, cryptorchidism, and hypospadias.

>

> OBJECTIVES:

> In this study, our objective was to assess the effect of serum TCDD

concentration on the risk of development of benign prostatic hyperplasia (BPH)

and on serum testosterone levels.

>

> METHODS:

> This study was a longitudinal, prospective cohort study made up of U.S. Air

Force veterans involved in Operation Ranch Hand. Other Air Force veterans who

did not spray herbicides were included as comparisons. BPH was determined by

medical record review and by medical examinations conducted during the study.

Data were available for 971 Ranch Hand and 1,266 comparison veterans. We

investigated the relationship between BPH and serum TCDD level using the

proportional hazards models adjusted for testosterone levels, body mass index

(BMI), and the percentage change in BMI per year.

>

> RESULTS:

> In univariate and multivariate analyses, the risk of BPH decreased with

increasing serum TCDD in the comparison group. The multivariate risk ratio for

BPH in the comparison group was 0.84 (95% confidence interval, 0.73-0.98).

Excluding men with prostate cancer, inflammatory or other prostatic diseases did

not substantially alter the association. Serum testosterone levels were

inversely associated with serum TCDD levels in both Ranch Hand and comparison

groups.

>

> CONCLUSIONS:

> TCDD exposure at general population levels is associated with a decreasing

risk of BPH with higher exposure levels. TCDD exposure is also negatively

associated with serum testosterone levels.

>

> - 65 yo super ob., fastidious male - 12mm X 13mm rt. a.adnoma with

previous rt. flank pain. Treating with DASH. Stats w/o meds = BP 175/90 HR 59

BS 125. D/C Spironolactone 12/20/2011 due to adverse SX.

> Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, Gynecomastia,

MDD and PTSD.

> Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, AmlodipineBesylate

10mg, 81mg aspirin and Metformin 2000MG. Started washing Spironolactone 12/20/11

to prepare for AVS.

>

[Guest guest]

Sometimes we have to write for the older cheaper one first or the insurance will not pay for it, We have to document why someone will not or cannot take it. It is not always just a preference of one over the other or that simple. Maybe on some insurances, but not always.

From: maggiekat7 <ljurkovic@...>Subject: Re: Agent Orange and Man Boobshyperaldosteronism Date: Thursday, February 2, 2012, 12:16 PM

During my last visit with the nephrologist who doesn't like working with NIH, she prescribed me Spiro. When I asked her why Spiro over Epler, since Epler is selective, etc., she said, yeah, but women like Spiro! She went on about how it improves women's skin, adult onset acne issues and how women give her glowing feedback about it's side effects. She assured me that I would like it, even though I protested, saying that I don't have acne, so maybe I wouldn't be in the category for women who want that side effect? She encouraged me to try it, since it's older, and it also helps with hirsitism...(sp?)...gets rid of those nasty hairs we women past menopause have to deal with. I said, doesn't it also cause women to have sore, more dense breasts? And maybe I want to avoid that since my Mom had fibrocystic dense breasts? Well, she said, if you don't like it, we can switch you to Epler, but she really thought I'd like it, and wrote the script for it. Just

thought you might get a kick out of that. After I get evaluated at NIH, if they suggest Epler or Spiro, I hope the conversation will be based on research and possibly the results of good labs and valid tests and even possibly, me, as an idividual. Wouldn't that be great?>> Does Agent Orange cause gyneocomastia? Maybe if you add a small dose of Spironolactone! > > Source: http://www.ncbi.nlm.nih.gov/pubmed/17107848> > Serum dioxin, testosterone, and subsequent risk of benign prostatic hyperplasia: a prospective cohort study of Air Force veterans.> >

Gupta A, Ketchum N, Roehrborn CG, Schecter A, Aragaki CC, Michalek JE. > Source> The University of Texas School of Public Health, Regional Campus at Dallas, Dallas, Texas 75390-9110, USA. amit.gupta@...> Abstract> > BACKGROUND: > Operation Ranch Hand veterans were involved in spraying herbicides, including Agent Orange, during the Vietnam War in 1962-1971; Agent Orange was contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). It has been hypothesized that dioxins may be partially responsible for an increase of male reproductive tract disorders such as testicular cancer, cryptorchidism, and hypospadias.> > OBJECTIVES: > In this study, our objective was to assess the effect of serum TCDD concentration on the risk of development of benign prostatic hyperplasia (BPH) and on serum testosterone levels.> > METHODS: > This study was a longitudinal, prospective cohort

study made up of U.S. Air Force veterans involved in Operation Ranch Hand. Other Air Force veterans who did not spray herbicides were included as comparisons. BPH was determined by medical record review and by medical examinations conducted during the study. Data were available for 971 Ranch Hand and 1,266 comparison veterans. We investigated the relationship between BPH and serum TCDD level using the proportional hazards models adjusted for testosterone levels, body mass index (BMI), and the percentage change in BMI per year.> > RESULTS: > In univariate and multivariate analyses, the risk of BPH decreased with increasing serum TCDD in the comparison group. The multivariate risk ratio for BPH in the comparison group was 0.84 (95% confidence interval, 0.73-0.98). Excluding men with prostate cancer, inflammatory or other prostatic diseases did not substantially alter the association. Serum testosterone levels were inversely

associated with serum TCDD levels in both Ranch Hand and comparison groups.> > CONCLUSIONS: > TCDD exposure at general population levels is associated with a decreasing risk of BPH with higher exposure levels. TCDD exposure is also negatively associated with serum testosterone levels.> > - 65 yo super ob., fastidious male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with DASH. Stats w/o meds = BP 175/90 HR 59 BS 125. D/C Spironolactone 12/20/2011 due to adverse SX.> Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, Gynecomastia, MDD and PTSD.> Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, AmlodipineBesylate 10mg, 81mg aspirin and Metformin 2000MG. Started washing Spironolactone 12/20/11 to prepare for AVS.>

[Guest guest]

Maybe msmith is available as a consultant for the right price!

> >

> > Does Agent Orange cause gyneocomastia? Maybe if you add a small dose of

Spironolactone!

> >

> > Source: http://www.ncbi.nlm.nih.gov/pubmed/17107848

> >

> > Serum dioxin, testosterone, and subsequent risk of benign prostatic

hyperplasia: a prospective cohort study of Air Force veterans.

> >

> > Gupta A, Ketchum N, Roehrborn CG, Schecter A, Aragaki CC, Michalek JE.

> > Source

> > The University of Texas School of Public Health, Regional Campus at Dallas,

Dallas, Texas 75390-9110, USA. amit.gupta@

> > Abstract

> >

> > BACKGROUND:

> > Operation Ranch Hand veterans were involved in spraying herbicides,

including Agent Orange, during the Vietnam War in 1962-1971; Agent Orange was

contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). It has been

hypothesized that dioxins may be partially responsible for an increase of male

reproductive tract disorders such as testicular cancer, cryptorchidism, and

hypospadias.

> >

> > OBJECTIVES:

> > In this study, our objective was to assess the effect of serum TCDD

concentration on the risk of development of benign prostatic hyperplasia (BPH)

and on serum testosterone levels.

> >

> > METHODS:

> > This study was a longitudinal, prospective cohort study made up of U.S. Air

Force veterans involved in Operation Ranch Hand. Other Air Force veterans who

did not spray herbicides were included as comparisons. BPH was determined by

medical record review and by medical examinations conducted during the study.

Data were available for 971 Ranch Hand and 1,266 comparison veterans. We

investigated the relationship between BPH and serum TCDD level using the

proportional hazards models adjusted for testosterone levels, body mass index

(BMI), and the percentage change in BMI per year.

> >

> > RESULTS:

> > In univariate and multivariate analyses, the risk of BPH decreased with

increasing serum TCDD in the comparison group. The multivariate risk ratio for

BPH in the comparison group was 0.84 (95% confidence interval, 0.73-0.98).

Excluding men with prostate cancer, inflammatory or other prostatic diseases did

not substantially alter the association. Serum testosterone levels were

inversely associated with serum TCDD levels in both Ranch Hand and comparison

groups.

> >

> > CONCLUSIONS:

> > TCDD exposure at general population levels is associated with a decreasing

risk of BPH with higher exposure levels. TCDD exposure is also negatively

associated with serum testosterone levels.

> >

> > - 65 yo super ob., fastidious male - 12mm X 13mm rt. a.adnoma with

previous rt. flank pain. Treating with DASH. Stats w/o meds = BP 175/90 HR 59

BS 125. D/C Spironolactone 12/20/2011 due to adverse SX.

> > Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, Gynecomastia,

MDD and PTSD.

> > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, AmlodipineBesylate

10mg, 81mg aspirin and Metformin 2000MG. Started washing Spironolactone 12/20/11

to prepare for AVS.

> >

>