Re: My story - from a newbie

[Guest guest]

What is the BP IN your legs?Has your arm been measured to select the correct cuff. Is it ever taken by a person who listens to the BP?May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertensionOn Mar 26, 2012, at 20:35, danielle_cairns <danielle_cairns@...> wrote:

Hi Everyone,

I wrote a few posts yesterday but the Dr. asked that I provide my detailed story with lab #'s so here it goes. I am a 33yo female that was incidentally diagnosed with a right adrenal tumor (~2cm) about 5 years ago that was deemed non-malignant and non-functioning. They kept an eye on it for about 2.5 years. Then my gynecologist told me that it "disappeared" after I had a scan done for my endometriosis. Turns out, he was wrong. The tumor is here and now they think it's producing aldosterone. I went to the Dr. for extreme fatigue, rapid weight gain (25-30 lbs in 6-8 months), night sweats/excess sweating and blood sugar fluctuations. The doc says it is hyperaldosteronism and we are following up with a few more tests and discussing surgical/treatment options. These are my test results:

*PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h NORMAL

*ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

*ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

*CORTISOL, TOTAL: 22.7 mcg/dL HIGH

*POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

*HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb NORMAL

*INSULIN: 5 RANGE: <17 uIU/mL NORMAL

*DHEA,ACTH, Glucose tol. test = ALL NORMAL

Other abnormal tests:

*CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

*TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

*GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

*CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

My BP is low to normal: like 70/100 or so.

Any thoughts/feedback/advice is much appreciated! Thanks! le

[Guest guest]

looks to me (IMHO) that you may have concurrent hyperaldosteronism and

hypercortisolism, which occurs in about 21% of people with adrenal adenomas.

They not only need to do AVS, but also a dexamethasone suppression test, esp. at

your age! Could preclude issues like ovarian cysts, infertility, miscarriages.

Wish I had found out before all that.

>

> Hi Everyone,

>

> I wrote a few posts yesterday but the Dr. asked that I provide my detailed

story with lab #'s so here it goes. I am a 33yo female that was incidentally

diagnosed with a right adrenal tumor (~2cm) about 5 years ago that was deemed

non-malignant and non-functioning. They kept an eye on it for about 2.5 years.

Then my gynecologist told me that it " disappeared " after I had a scan done for

my endometriosis. Turns out, he was wrong. The tumor is here and now they think

it's producing aldosterone. I went to the Dr. for extreme fatigue, rapid weight

gain (25-30 lbs in 6-8 months), night sweats/excess sweating and blood sugar

fluctuations. The doc says it is hyperaldosteronism and we are following up with

a few more tests and discussing surgical/treatment options. These are my test

results:

>

> *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h NORMAL

> *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

>

> *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb NORMAL

> *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> *DHEA,ACTH, Glucose tol. test = ALL NORMAL

>

> Other abnormal tests:

> *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

>

> My BP is low to normal: like 70/100 or so.

>

> Any thoughts/feedback/advice is much appreciated! Thanks! le

>

[Guest guest]

Thanks for writing. I just got the results from my dexmethasone suppression test

today and it was normal (below ref range in fact). I also got new renin (2.35),

aldo (121 ng/ml) and ratio levels (51.5). I also found out my pancreatic

polypeptide and DHEA sulfate levels are low along with my carbon dioxide and vit

D. No wonder I feel so crumby. I sure hope these results help my doctor figure

out next steps! Thanks for your help!

> >

> > Hi Everyone,

> >

> > I wrote a few posts yesterday but the Dr. asked that I provide my detailed

story with lab #'s so here it goes. I am a 33yo female that was incidentally

diagnosed with a right adrenal tumor (~2cm) about 5 years ago that was deemed

non-malignant and non-functioning. They kept an eye on it for about 2.5 years.

Then my gynecologist told me that it " disappeared " after I had a scan done for

my endometriosis. Turns out, he was wrong. The tumor is here and now they think

it's producing aldosterone. I went to the Dr. for extreme fatigue, rapid weight

gain (25-30 lbs in 6-8 months), night sweats/excess sweating and blood sugar

fluctuations. The doc says it is hyperaldosteronism and we are following up with

a few more tests and discussing surgical/treatment options. These are my test

results:

> >

> > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h NORMAL

> > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

> >

> > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb NORMAL

> > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> > *DHEA,ACTH, Glucose tol. test = ALL NORMAL

> >

> > Other abnormal tests:

> > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

> >

> > My BP is low to normal: like 70/100 or so.

> >

> > Any thoughts/feedback/advice is much appreciated! Thanks! le

> >

>

[Guest guest]

Please refer message 41770 for the 21% figure. It is a report from this study:

http://www.jstage.jst.go.jp/article/endocrj/58/7/543/_pdf

> > >

> > > Hi Everyone,

> > >

> > > I wrote a few posts yesterday but the Dr. asked that I provide my

> > detailed story with lab #'s so here it goes. I am a 33yo female that

> > was incidentally diagnosed with a right adrenal tumor (~2cm) about 5

> > years ago that was deemed non-malignant and non-functioning. They

> > kept an eye on it for about 2.5 years. Then my gynecologist told me

> > that it " disappeared " after I had a scan done for my endometriosis.

> > Turns out, he was wrong. The tumor is here and now they think it's

> > producing aldosterone. I went to the Dr. for extreme fatigue, rapid

> > weight gain (25-30 lbs in 6-8 months), night sweats/excess sweating

> > and blood sugar fluctuations. The doc says it is hyperaldosteronism

> > and we are following up with a few more tests and discussing

> > surgical/treatment options. These are my test results:

> > >

> > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h

> > NORMAL

> > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

> > >

> > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb NORMAL

> > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL

> > >

> > > Other abnormal tests:

> > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

> > >

> > > My BP is low to normal: like 70/100 or so.

> > >

> > > Any thoughts/feedback/advice is much appreciated! Thanks! le

> > >

> >

> >

>

[Guest guest]

, I'm not sure what you are implying with your first comment. This article was probably written in Japanese, translated by someone and published by someone else so anybody could have committed that typo. I don't see as it really has any bearing on the content! It's a 2011 research report and released im advance of publication.

As for how they determined the cortisol they explained that on page 2 (544) of the report. I don't know enough about Cushing to know if that is a valid answer to your question but you and Dr. Grim could take position on that! (My guess is others have reviewed it since it took > 4 months to publish it!) As far as I can tell it is a fairly new finding and could have an impact on care and treatment. (It could also turn out to be total B.S. but I bet Maggie will disagree!) I raised a couple questions on both sides of the issue that immediately came to mind and I'm sure there are many more. Refer to post #41770 for a start.

BTW, if you find typos in my postings see if I'm missing an "a", my keyboard needs replacing but I used the $$$ for a r/t ticket to Bethesda! I also might be off one key but that a vision problem! In reality I can't spell "FOR SHIT"! (Woops, I guess I just did!)

> > > >> > > > Hi Everyone,> > > >> > > > I wrote a few posts yesterday but the Dr. asked that I provide my > > > detailed story with lab #'s so here it goes. I am a 33yo female that > > > was incidentally diagnosed with a right adrenal tumor (~2cm) about 5 > > > years ago that was deemed non-malignant and non-functioning. They > > > kept an eye on it for about 2.5 years. Then my gynecologist told me > > > that it "disappeared" after I had a scan done for my endometriosis. > > > Turns out, he was wrong. The tumor is here and now they think it's > > > producing aldosterone. I went to the Dr. for extreme fatigue, rapid > > > weight gain (25-30 lbs in 6-8 months), night sweats/excess sweating > > > and blood sugar fluctuations. The doc says it is hyperaldosteronism > > > and we are following up with a few more tests and discussing > > > surgical/treatment options. These are my test results:> > > >> > > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h > > > NORMAL> > > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH> > > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH> > > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH> > > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL> > > >> > > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb NORMAL> > > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL> > > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL> > > >> > > > Other abnormal tests:> > > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH> > > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH> > > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW> > > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L> > > >> > > > My BP is low to normal: like 70/100 or so.> > > >> > > > Any thoughts/feedback/advice is much appreciated! Thanks! le> > > >> > >> > >> >>

[Guest guest]

Please understand that in my professional career I managed the technical writers

for years. When we published something it went through many reviews and we

passed it through programs to check grammar, etc. When it was published it was

expected to be perfect and all critical information had been verified. Was

everything 100%? NO, but the critical information had better be! I read tons

of IBM, Microsoft, AT & T, etc. manuals. Were they all perfect? NO. I applied

updates to manuals myself when others had a clerk do it. I did it primarily to

see what had changed but many times it was spelling or grammar which made no

difference to the data or outcome! Spelling is simple for some but not others,

IMHE!

Since you brought up my discussions of depression and stress maybe we should

consider your views also. I get the feeling you have very little consideration

of these issues. You and I tend to be on the opposite ends of the spectrim. In

fact I've heard your opinion re SSRIs. When I make a statement regarding

depression and PTSD it is based on a study I have found. If you disagree, show

me the study, but don't question ME, I'm the messenger and I try to remain

neutral and report both sides of an issue. If you don't believe that the action

of Spironolctone affects Cortisol which in turn affects seratonin (which you are

trying to control with duloxetine) and the problem is exacerbated in PTN's w/MDD

because of some shortened loop in PTNs w/MDD that's fine with me! If you don't

believe there is a possibility of SCS in people with an adenoma and CONN's

that's okay with me but you can be assured they will check me starting next

week.

Some people believe you have to have a tumor to have CONN's, High K etc. I

don't believe Dr. Conn identified 5 different versions of hyperldosteronism back

in 1956 but we all know good research has identified all that and we accept it.

Is SCS indicated in 20% of the PTNs with PA? IDK but nobody will ever know if

we don't research it. Is it a reason to do further testing before you go in and

remove an adrenal that is producing excess adosterone? Is it reason to proceed

to ADx with caution? Is that DR. Grim right and you should proceed to ADx only

after MCB & DASH fail. We won't know unless others do quality/controlled

research and the professionals validate their findings. Somebody has to start

the process and I certainly hope it doesn't get derailed because they can't

spell " Cuhing's Syndrome " !

> > > > >

> > > > > Hi Everyone,

> > > > >

> > > > > I wrote a few posts yesterday but the Dr. asked that I provide my

> > > > detailed story with lab #'s so here it goes. I am a 33yo female that

> > > > was incidentally diagnosed with a right adrenal tumor (~2cm) about 5

> > > > years ago that was deemed non-malignant and non-functioning. They

> > > > kept an eye on it for about 2.5 years. Then my gynecologist told me

> > > > that it " disappeared " after I had a scan done for my endometriosis.

> > > > Turns out, he was wrong. The tumor is here and now they think it's

> > > > producing aldosterone. I went to the Dr. for extreme fatigue, rapid

> > > > weight gain (25-30 lbs in 6-8 months), night sweats/excess sweating

> > > > and blood sugar fluctuations. The doc says it is hyperaldosteronism

> > > > and we are following up with a few more tests and discussing

> > > > surgical/treatment options. These are my test results:

> > > > >

> > > > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h

> > > > NORMAL

> > > > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> > > > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> > > > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> > > > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

> > > > >

> > > > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb NORMAL

> > > > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> > > > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL

> > > > >

> > > > > Other abnormal tests:

> > > > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> > > > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> > > > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> > > > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

> > > > >

> > > > > My BP is low to normal: like 70/100 or so.

> > > > >

> > > > > Any thoughts/feedback/advice is much appreciated! Thanks! le

> > > > >

> > > >

> > > >

> > >

> >

>

[Guest guest]

Dr. G., Have you seen or heard much about this? Certainly agree there is much

to be done and much more controlled testing. Maybe Maggie will be able to shed

more light on it after " Round 2 " at NIH!

> > > > > >

> > > > > > Hi Everyone,

> > > > > >

> > > > > > I wrote a few posts yesterday but the Dr. asked that I

> > provide my

> > > > > detailed story with lab #'s so here it goes. I am a 33yo

> > female that

> > > > > was incidentally diagnosed with a right adrenal tumor (~2cm)

> > about 5

> > > > > years ago that was deemed non-malignant and non-functioning.

> > They

> > > > > kept an eye on it for about 2.5 years. Then my gynecologist

> > told me

> > > > > that it " disappeared " after I had a scan done for my

> > endometriosis.

> > > > > Turns out, he was wrong. The tumor is here and now they think

> > it's

> > > > > producing aldosterone. I went to the Dr. for extreme fatigue,

> > rapid

> > > > > weight gain (25-30 lbs in 6-8 months), night sweats/excess

> > sweating

> > > > > and blood sugar fluctuations. The doc says it is

> > hyperaldosteronism

> > > > > and we are following up with a few more tests and discussing

> > > > > surgical/treatment options. These are my test results:

> > > > > >

> > > > > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h

> > > > > NORMAL

> > > > > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> > > > > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> > > > > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> > > > > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

> > > > > >

> > > > > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb

> > NORMAL

> > > > > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> > > > > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL

> > > > > >

> > > > > > Other abnormal tests:

> > > > > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> > > > > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> > > > > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> > > > > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

> > > > > >

> > > > > > My BP is low to normal: like 70/100 or so.

> > > > > >

> > > > > > Any thoughts/feedback/advice is much appreciated! Thanks!

> > le

> > > > > >

> > > > >

> > > > >

> > > >

> > >

> >

> >

> >

>

[Guest guest]

, we can discount the first one, they don't know how to spell the word "standardised". (I believe it should be with a "z"!)

> > > > > > >> > > > > > > Hi Everyone,> > > > > > >> > > > > > > I wrote a few posts yesterday but the Dr. asked that I > > provide my> > > > > > detailed story with lab #'s so here it goes. I am a 33yo > > female that> > > > > > was incidentally diagnosed with a right adrenal tumor (~2cm) > > about 5> > > > > > years ago that was deemed non-malignant and non-functioning. > > They> > > > > > kept an eye on it for about 2.5 years. Then my gynecologist > > told me> > > > > > that it "disappeared" after I had a scan done for my > > endometriosis.> > > > > > Turns out, he was wrong. The tumor is here and now they > > think it's> > > > > > producing aldosterone. I went to the Dr. for extreme > > fatigue, rapid> > > > > > weight gain (25-30 lbs in 6-8 months), night sweats/excess > > sweating> > > > > > and blood sugar fluctuations. The doc says it is > > hyperaldosteronism> > > > > > and we are following up with a few more tests and discussing> > > > > > surgical/treatment options. These are my test results:> > > > > > >> > > > > > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/ > > mL/h> > > > > > NORMAL> > > > > > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH> > > > > > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH> > > > > > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH> > > > > > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL> > > > > > >> > > > > > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb > > NORMAL> > > > > > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL> > > > > > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL> > > > > > >> > > > > > > Other abnormal tests:> > > > > > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH> > > > > > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH> > > > > > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW> > > > > > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L> > > > > > >> > > > > > > My BP is low to normal: like 70/100 or so.> > > > > > >> > > > > > > Any thoughts/feedback/advice is much appreciated! Thanks! > > le> > > > > > >> > > > > >> > > > > >> > > > >> > > >> > >> >> >>

[Guest guest]

IMHO one of the problems with research in this area is what came first? And how

much did the patient suffer with the disease; from diagnosis nightmare to

collateral damage such as miscarriage, infertility, cardiac issues, glucose

issues, potassium issues? How do you control for the variables of current

symptomology associated with the disease and all of that? It would have to be a

pretty good study, that's for sure. I know the folks at Ludwig Max Univ. and I

can tell you, they do research that is second to none.

> > > > > > > >

> > > > > > > > Hi Everyone,

> > > > > > > >

> > > > > > > > I wrote a few posts yesterday but the Dr. asked that I

> > > provide my

> > > > > > > detailed story with lab #'s so here it goes. I am a 33yo

> > > female that

> > > > > > > was incidentally diagnosed with a right adrenal tumor (~2cm)

> > > about 5

> > > > > > > years ago that was deemed non-malignant and non-functioning.

> > > They

> > > > > > > kept an eye on it for about 2.5 years. Then my gynecologist

> > > told me

> > > > > > > that it " disappeared " after I had a scan done for my

> > > endometriosis.

> > > > > > > Turns out, he was wrong. The tumor is here and now they

> > > think it's

> > > > > > > producing aldosterone. I went to the Dr. for extreme

> > > fatigue, rapid

> > > > > > > weight gain (25-30 lbs in 6-8 months), night sweats/excess

> > > sweating

> > > > > > > and blood sugar fluctuations. The doc says it is

> > > hyperaldosteronism

> > > > > > > and we are following up with a few more tests and discussing

> > > > > > > surgical/treatment options. These are my test results:

> > > > > > > >

> > > > > > > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/

> > > mL/h

> > > > > > > NORMAL

> > > > > > > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> > > > > > > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> > > > > > > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> > > > > > > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

> > > > > > > >

> > > > > > > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb

> > > NORMAL

> > > > > > > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> > > > > > > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL

> > > > > > > >

> > > > > > > > Other abnormal tests:

> > > > > > > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> > > > > > > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> > > > > > > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> > > > > > > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

> > > > > > > >

> > > > > > > > My BP is low to normal: like 70/100 or so.

> > > > > > > >

> > > > > > > > Any thoughts/feedback/advice is much appreciated! Thanks!

> > > le

> > > > > > > >

> > > > > > >

> > > > > > >

> > > > > >

> > > > >

> > > >

> > >

> > >

> >

>

[Guest guest]

Dr. M. at NIH was one of the reviewers for this study. He has since told me that

there are three groups of researchers in this area; the USA, Italy and Japan.

Japanese research subjects, he said, eat way more salt than the US subjects,

overall, and their research has other differences, such as their normal values

for protocols. In any case, it might be good to read his review, he is one fine

Dr.

> > > > > >

> > > > > > Hi Everyone,

> > > > > >

> > > > > > I wrote a few posts yesterday but the Dr. asked that I

> > provide my

> > > > > detailed story with lab #'s so here it goes. I am a 33yo

> > female that

> > > > > was incidentally diagnosed with a right adrenal tumor (~2cm)

> > about 5

> > > > > years ago that was deemed non-malignant and non-functioning.

> > They

> > > > > kept an eye on it for about 2.5 years. Then my gynecologist

> > told me

> > > > > that it " disappeared " after I had a scan done for my

> > endometriosis.

> > > > > Turns out, he was wrong. The tumor is here and now they think

> > it's

> > > > > producing aldosterone. I went to the Dr. for extreme fatigue,

> > rapid

> > > > > weight gain (25-30 lbs in 6-8 months), night sweats/excess

> > sweating

> > > > > and blood sugar fluctuations. The doc says it is

> > hyperaldosteronism

> > > > > and we are following up with a few more tests and discussing

> > > > > surgical/treatment options. These are my test results:

> > > > > >

> > > > > > *PLASMA RENIN ACTIVITY,LC/MS/MS: 2.24 RANGE: 0.25-5.82 ng/mL/h

> > > > > NORMAL

> > > > > > *ALDO/PRA RATIO: 41.1 RANGE: 0.9-28.9 Ratio HIGH

> > > > > > *ALDOSTERONE, LC/MS/MS: 92 g/dL HIGH

> > > > > > *CORTISOL, TOTAL: 22.7 mcg/dL HIGH

> > > > > > *POTASSIUM: 4.4 Range: 3.5-5.3 mmol/L NORMAL

> > > > > >

> > > > > > *HEMOGLOBIN A1c: 5.1 (NORMAL) RANGE: <5.7 % of total Hgb

> > NORMAL

> > > > > > *INSULIN: 5 RANGE: <17 uIU/mL NORMAL

> > > > > > *DHEA,ACTH, Glucose tol. test = ALL NORMAL

> > > > > >

> > > > > > Other abnormal tests:

> > > > > > *CHOLESTEROL: TOTAL 209 RANGE: 125-200 mg/dL HIGH

> > > > > > *TRIGLYCERIDES: 299 RANGE: <150 mg/dL HIGH

> > > > > > *GLUCOSE: 61 RANGE: 65-99 mg/dL LOW

> > > > > > *CARBON DIOXIDE: 17 RANGE: 21-33 mmol/L

> > > > > >

> > > > > > My BP is low to normal: like 70/100 or so.

> > > > > >

> > > > > > Any thoughts/feedback/advice is much appreciated! Thanks!

> > le

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