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JC - NIH Info

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We meant yesterday afternoon when they " released " me. And I will share a little

here but I actually know little more than you.

The word Dr. M. used is " 17-Hydroxy-steroids. " 5 min. summary is here….

This is as far as I got before I literally ran out of gas last night! I woke up

4 hrs later, went to bed and now it is 5 am and I will finish that thought!

From the patent info: 17-Hydroxy-steroids

Patent 4898694 Issued on February 6, 1990

BACKGROUND OF THE INVENTION

This invention relates to novel steroids and more particularly to androsterone

derivatives useful as anti-cancer, anti-obesity, anti-diabetic, and

hypolipidemic agents and useful for combatting coronary diseases.

I'm early in understanding but it appears this or a mutation is suspected to be

in my gene pool./

Okay, 3d try and I will send this today whether or not I get it finished! I

don't know much more since I spent last night in the ER.

I knew early that they were investigating hyperaldosteronism as a " masking "

condition and were more concerned about what was hiding behind it. They were

quite surprised when I used the term CYP11B1 because this is apparently a close

relative of Cortisol. That is likely why Spironolactone is not right in this

condition. When there is already an excess cort issue and the action of spiro

increases it more it becomes a " DOUBLE WHAMMY " ! Sorry for the technical jargon,

I'll work on the complete answer, maybe!

I'll send this now before I get distracted again. I still need to figure out

where this trip is headed but am honored to have a front row seat! We'll need

to decide how much you want to know.

.....

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