Guest guest Posted October 10, 2000 Report Share Posted October 10, 2000 Hi, My name is Elaine and I gave birth to twin sons 10/19/99. I was 36 when pregnant and 37 when I delivered. (normal) was 8 lb 15 oz and (DS) was 6 lb 2 oz. I was 39 weeks pregnant when I went into labor (C-section). All of my ultrasounds (every 4 weeks or so) showed a little smaller and his head a little smaller but still within the normal range but the discrepancy grew the last 2 months to 20% size difference. I too, elected no amnio and no AFP test for the same reasons....However...at 24 weeks, I had a " level 2 " ultrasound and it showed having Choroid Plexus Cysts. They were bi-lateral, meaning in both hemisheres of the brain...at any rate, these cysts were not thought to be markers for DS, but possibly linked to Trisomy 18, which would have been fatal to the baby shortly after birth. Also, just a " mom " thing, but kicked the devil out of me and turned alot, and s movements were softer, more like brushes and waves. was in severe distress (Apgar 1) when born, and also had a birth defect, imperforate anus, which means he has a colostomy. also suffered from infantile spasms, a severe form of seizure.The boys turn 1 next week. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2000 Report Share Posted October 11, 2000 It's Trisomy 21 !! Yep, that's us! BTW, I missed the chance to welcome you. I'm Sara... list owner for this group of fabulous folks and webmaster for DSyndrome.com. I'm a 20 year old " DS Groupie " (name I recieved from the UpsnDowns crew) and medical student, with a minor in International Political Theories, at UB in NY. Anyway, welcome! Cheers! Sara --On Wednesday, October 11, 2000, 4:16 PM -0700 Torry <tlcesq@...> wrote: > Is it Trisomy 18 which is D.S., or Trisomy 21? > > Torry > > RE:Research > > >> >> Hi, >> My name is Elaine and I gave birth to twin sons 10/19/99. I was 36 >> when pregnant and 37 when I delivered. (normal) was 8 lb 15 oz >> and (DS) was 6 lb 2 oz. I was 39 weeks pregnant when I went into >> labor (C-section). All of my ultrasounds (every 4 weeks or so) showed >> a little smaller and his head a little smaller but still within the >> normal range but the discrepancy grew the last 2 months to 20% size >> difference. I too, elected no amnio and no AFP test for the same > reasons....However...at >> 24 weeks, I had a " level 2 " ultrasound and it showed having Choroid >> Plexus Cysts. They were bi-lateral, meaning in both hemisheres of the >> brain...at any rate, these cysts were not thought to be markers for DS, > but >> possibly linked to Trisomy 18, which would have been fatal to the baby >> shortly after birth. Also, just a " mom " thing, but kicked the > devil >> out of me and turned alot, and s movements were softer, more like >> brushes and waves. was in severe distress (Apgar 1) when born, and > also >> had a birth defect, imperforate anus, which means he has a colostomy. >> also suffered from infantile spasms, a severe form of seizure.The >> boys > turn >> 1 next week. >> >> >> >> http://DSyndrome.com/Multiples >> > > > > http://DSyndrome.com/Multiples > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2000 Report Share Posted October 11, 2000 Thank you, Elaine. I have not seen any information before concerning the choroid plexus cysts. Do you know whether these are considered one of the " markers " for DS screening during ultrasound? We're hopefully having another Level 2 ultrasound tomorrow, and I will ask our perinatologist about this. My OB told me that I'll start having ultrasounds every two weeks after this visit, since I am now @ 20 weeks. I hope from the various e-mail responses I've received that we'll be able to receive Level 2 ultrasounds from now on, and frequently. Torry RE:Research > > Hi, > My name is Elaine and I gave birth to twin sons 10/19/99. I was 36 > when pregnant and 37 when I delivered. (normal) was 8 lb 15 oz and > (DS) was 6 lb 2 oz. I was 39 weeks pregnant when I went into labor > (C-section). All of my ultrasounds (every 4 weeks or so) showed a > little smaller and his head a little smaller but still within the normal > range but the discrepancy grew the last 2 months to 20% size difference. > I too, elected no amnio and no AFP test for the same reasons....However...at > 24 weeks, I had a " level 2 " ultrasound and it showed having Choroid > Plexus Cysts. They were bi-lateral, meaning in both hemisheres of the > brain...at any rate, these cysts were not thought to be markers for DS, but > possibly linked to Trisomy 18, which would have been fatal to the baby > shortly after birth. Also, just a " mom " thing, but kicked the devil > out of me and turned alot, and s movements were softer, more like > brushes and waves. was in severe distress (Apgar 1) when born, and also > had a birth defect, imperforate anus, which means he has a colostomy. > also suffered from infantile spasms, a severe form of seizure.The boys turn > 1 next week. > > > > http://DSyndrome.com/Multiples > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2000 Report Share Posted October 11, 2000 Is it Trisomy 18 which is D.S., or Trisomy 21? Torry RE:Research > > Hi, > My name is Elaine and I gave birth to twin sons 10/19/99. I was 36 > when pregnant and 37 when I delivered. (normal) was 8 lb 15 oz and > (DS) was 6 lb 2 oz. I was 39 weeks pregnant when I went into labor > (C-section). All of my ultrasounds (every 4 weeks or so) showed a > little smaller and his head a little smaller but still within the normal > range but the discrepancy grew the last 2 months to 20% size difference. > I too, elected no amnio and no AFP test for the same reasons....However...at > 24 weeks, I had a " level 2 " ultrasound and it showed having Choroid > Plexus Cysts. They were bi-lateral, meaning in both hemisheres of the > brain...at any rate, these cysts were not thought to be markers for DS, but > possibly linked to Trisomy 18, which would have been fatal to the baby > shortly after birth. Also, just a " mom " thing, but kicked the devil > out of me and turned alot, and s movements were softer, more like > brushes and waves. was in severe distress (Apgar 1) when born, and also > had a birth defect, imperforate anus, which means he has a colostomy. > also suffered from infantile spasms, a severe form of seizure.The boys turn > 1 next week. > > > > http://DSyndrome.com/Multiples > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2000 Report Share Posted October 11, 2000 Hey Torry, Trisomy 21 is down syndrome. Elaine, we got a trisomy 13 scare when was born. The neonatologist said that he thought it was 13, apparently it looks similar to ds and a cleft lip and palate is common with it. He told us point blank day 1 that if it was, he wouldn't survive the first year. Ouch! We were so glad that it was 21, although we did have to do a good amount of adjusting with that too! I have done a little surfing to find out about trisomy 13, but still don't really know much about it. I don't know what the markers are for that or what he saw that made him think 13 other than the clefts. Does anyone know if some of the ds features or markers are also the same for other trisomies? Torry, that might be a question for your doctor tomorrow also. Has anyone else received other preliminary diagnoses than tri 21? I would be interested in learning more about these other trisomies, if anyone has any additional information. (wife of Rob and mom of 10 month old twins (ds/cl & p) and ) http://sites.netscape.net/cabevizzo/homepage Life is what happens to you while you're busy making other plans. ______________________________________________ FREE Personalized Email at Mail.com Sign up at http://www.mail.com/?sr=signup Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2000 Report Share Posted October 11, 2000 Thanks for the welcome, Sara. Since you're " in the field, " I was wondering whether you could lead me to any research re DS and twins -- especially ultrasound markers. I have found a number of studies through the National Library of Medicine that appear helpful, and I will try to use the information already gleaned when we meet with the perinatologist tomorrow. But if there's more out there that can be helpful, I would appreciate it. Torry RE:Research > > > > > >> > >> Hi, > >> My name is Elaine and I gave birth to twin sons 10/19/99. I was 36 > >> when pregnant and 37 when I delivered. (normal) was 8 lb 15 oz > >> and (DS) was 6 lb 2 oz. I was 39 weeks pregnant when I went into > >> labor (C-section). All of my ultrasounds (every 4 weeks or so) showed > >> a little smaller and his head a little smaller but still within the > >> normal range but the discrepancy grew the last 2 months to 20% size > >> difference. I too, elected no amnio and no AFP test for the same > > reasons....However...at > >> 24 weeks, I had a " level 2 " ultrasound and it showed having Choroid > >> Plexus Cysts. They were bi-lateral, meaning in both hemisheres of the > >> brain...at any rate, these cysts were not thought to be markers for DS, > > but > >> possibly linked to Trisomy 18, which would have been fatal to the baby > >> shortly after birth. Also, just a " mom " thing, but kicked the > > devil > >> out of me and turned alot, and s movements were softer, more like > >> brushes and waves. was in severe distress (Apgar 1) when born, and > > also > >> had a birth defect, imperforate anus, which means he has a colostomy. > >> also suffered from infantile spasms, a severe form of seizure.The > >> boys > > turn > >> 1 next week. > >> > >> > >> > >> http://DSyndrome.com/Multiples > >> > > > > > > > > http://DSyndrome.com/Multiples > > > > > > > > > http://DSyndrome.com/Multiples > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 11, 2000 Report Share Posted October 11, 2000 Thank you, Elaine, for your e-mail. I did come across one study from the National Library of Medicine which mentioned choroid plexus cysts as a potential ultrasound marker. I'll ask my perinatologist about it tomorrow. Torry RE:Research > > Hi, > My name is Elaine and I gave birth to twin sons 10/19/99. I was 36 > when pregnant and 37 when I delivered. (normal) was 8 lb 15 oz and > (DS) was 6 lb 2 oz. I was 39 weeks pregnant when I went into labor > (C-section). All of my ultrasounds (every 4 weeks or so) showed a > little smaller and his head a little smaller but still within the normal > range but the discrepancy grew the last 2 months to 20% size difference. > I too, elected no amnio and no AFP test for the same reasons....However...at > 24 weeks, I had a " level 2 " ultrasound and it showed having Choroid > Plexus Cysts. They were bi-lateral, meaning in both hemisheres of the > brain...at any rate, these cysts were not thought to be markers for DS, but > possibly linked to Trisomy 18, which would have been fatal to the baby > shortly after birth. Also, just a " mom " thing, but kicked the devil > out of me and turned alot, and s movements were softer, more like > brushes and waves. was in severe distress (Apgar 1) when born, and also > had a birth defect, imperforate anus, which means he has a colostomy. > also suffered from infantile spasms, a severe form of seizure.The boys turn > 1 next week. > > > > http://DSyndrome.com/Multiples > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 31, 2009 Report Share Posted December 31, 2009 Very interesting Lois!Sent from my BlackBerry Smartphone provided by AlltelFrom: " lois noland" <jlois@...>Date: Wed, 30 Dec 2009 21:29:31 -0500<autism >; <WACASA >; <H_A_P_P_Y_ >; Jim Lynch \(E-mail\)<lynch@...>; <xander95608@...>Subject: Research RESEARCHAutism is Characterized by Dorsal Anterior Cingulate Hyperactivation During Social Target Detection S. Dichter; N. Felder; W. Bodfish Posted: 12/28/2009; Social Cognitive and Affective Neuroscience. 2009;4(3):215-226. © 2009 medscape.com is.gd/5GKT8Abstract and IntroductionAbstract Though the functional neural correlates of impaired cognitive control and social dysfunction in autism spectrum disorders (ASD) have been delineated, brain regions implicated in poor cognitive control of social information is a novel area of autism research. We recently reported in a non-clinical sample that detection of 'social oddball' targets activated a portion of the dorsal anterior cingulate gyrus and the supracalcarine cortex (Dichter, Felder, Bodfish, Sikich, and Belger, 2009). In the present investigation, we report functional magnetic resonance imaging results from individuals with ASD who completed the same social oddball task. Between-group comparisons revealed generally greater activation in the ASD group to both social and non-social targets. When responses to social and non-social targets were contrasted, the ASD group showed relatively greater activation in the right and middle inferior frontal gyri and a region in dorsomedial prefrontal cortex that abuts the dorsal anterior cingulate (Brodmann's Area 32). Further, dorsal anterior cingulate activation to social targets predicted the severity of social impairments in a subset of the ASD sample. These data suggest that the dorsal anterior cingulate mediates social target detection in neurotypical individuals and is implicated in deficits of cognitive control of social information in ASD.Introduction The purpose of this study was to examine patterns of regional brain activation in individuals with autism spectrum disorders (ASD) during a target detection task that involved both social and non-social components. Whereas previous studies have demonstrated that individuals with ASD show anomalous brain activation during target detection tasks (Gomot et al., 2008; Shafritz et al., 2008), these studies used tasks that involved non-social information. However, the social cognitive deficits that are the sine qua non of autism should produce a unique pattern of responses during tasks that press for cognitive control of social information. Such tasks would represent a reasonable facsimile of everyday social situations wherein successful adaptation requires the identification of relevant and irrelevant social cues as well as the differential processing of social and non-social sources of information.+ Read more: is.gd/5GKT8DO SOMETHING ABOUT AUTISM NOW. . . Read, then Forward the Schafer Autism Report.$35 for 1 year - or free!www.sarnet.org • • •Lois Noland 240-420-6120Always in search for the "cure" Lois Noland240-420-3692I don't give inI don't give upAnd I don't take no for an answerAlways looking for the "Cure" I don't give inI don't give upAnd I don't take NO for an answer. If God Brings you to it,He will Bring you though it. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 8, 2012 Report Share Posted May 8, 2012 Where are they currently doing research on PA? Quote Link to comment Share on other sites More sharing options...
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