Make Your Own Liposomal Encapsulated Vitamin C

[Guest guest]

I became aware of this through the silver list and think its important enough to share.

This is for research purposes only.

« Make Your Own Liposomal Encapsulated Vitamin CFrom: BradleySent: Tuesday, August 11, 2009 12:20 PMTo:Subject: CS>Liposomal Encapsulation Technology: Vit “Câ€In our recent researches evaluating this technology and, consequently, in searching for possible “process†improvements/modifications which might facilitate the “lay person†an opportunity for a DIY methodology achievable in a home environment—we did achieve some notable progress.First, a brief summary of our exploratory activity. Our literature searches revealed several companies actively exhibiting valid capability in this area (LET).Typical, and demonstrably capable, is a company named MICROTEK. Microteklabs.comHelpful information is available here.One fact became obvious, early

on, to wit: The truly striking feature of LET was a NATURALLY-occurring characteristic…… and not a man-made process, that was driving this encapsulation process. That is, this process is a function of an automatic, “natural tendency†of certain substances (e.g. phospholipids in this case) to form tiny vacoules orbubbles—called liposomes—-when in a aqueous solution under certain conditions. â€The keystone activity is that these liposomes automatically fill themselves with whatever aqueous solution they were in—-before they were formed. “This type of bubble, called a membrane, forms a protective barrier around virtually every cell in the human body.â€Livon Labs has perfected a process which employs a high-pressure (1700 p.s.i.) discharge system which directs a liquid stream against a forming plate. The high impact forces the phospholipids (soy lecithin in this case) to form liposomes—-so small they require an electrom

microscope for viewing. This technology does not create the LET activity….it just enhances it. In our personal researches we have determined the key to exploiting the LET phenomenon appeared to be Livon’s application of intense force in their mixing methodology.Enter the “enlightening†moment. Searching for a method of achieving liposomal encapsulation, it occurred to us to explore ultrasonic stimulation as an option. It worked…maybe not quite as well as Livon’s “high tech†brute force approach…but about 70% as well. Plenty efficient for our purposes.Our vitamin “C†liposomal encapsulation protocol is as follows:Using a small (2 cup) Ultrasonic cleaner, (Item #03305, obtainable from Harbor Freight @ about $30.00), we performed the following:1. Dissolved 3 level tablespoons of soy lecithin in 1

cup of water (preferably distilled).2. Dissolved 1 level tablespoon of ascorbic acid powder (Vit. “Câ€) in 1/2 cupof water.3. Poured both solutions together in the ultrasonic cleaner bowl and turned the unit on. Using a plastic straw (leaving the top of the cleaner opened), gently, slowly, stirred the contents. Note: The cleaner will, automatically, self-stop about every 2 minutes. Just push ON button to continue. Repeat for a total of 3 series (6 minutes). By that time the entire solution should be blended into a cloudy, homogeneous,milk-like mixture. The LET solution is now formed.4. This protocol furnishes about 12 grams (12000mg.) of vitamin C product. At 70% encapsulation efficiency, 8400 mg would be of the LET type. This solution will keep, acceptably, at room temperature for 3 to 4 days. Refrigerated, it will keep much longer.We use it so fast around our place…there isn’t enough left to be concerned over storage.

The “homogenizing effect†is so powerful that after 3 days at room temperature, no precipitation or solution separation appears evident. This type of sequestered vitamin “C†has demonstrated to be, at least 5 times more effective (per volumetric measure) than any other form of orally-ingested vitamin “câ€â€¦.that we have tested.Additionally, it appears to be even more rapid in tissue-bed availability—-than IV applications. An astounding revelation….to us. We estimate the DIY researcher can produce the active LET portion of this solution for 15 cents per gram….as against about $1.00 per gram from commerci! al sources.It is my hope that this, limited, explanation of our activities in this area,is of some value to our do-it-yourself health-maintenance researchers. In any event, this protocol has demonstrated to be n on-toxic and most helpful to OUR RESEARCHES.Sincerely, Bradley.p.s. A larger, more powerful,

ultrasonic cleaner is now available at Harbor Freight. Item number 91593. 2+ liters, for about $60.00. Both units have performed quite well for us. Almost as well as our $500.00 lead zirconate titanate, research grade, unit.

Wilkins

Join Granny Warrior in a freedom loving intentional community for safety in troubled times.

http://www.freedomisnotdead.org/freedom.htm

use me as the referal to save $100 on a campsite or $500 on an acre

http://www.chews4health.com/Wilkins

http://www.simplexityhealth.com/ distributor#2005722

[Guest guest]

Looks like item number and price below is incorrect.

http://www.harborfreight.com/cpi/ctaf/displayitem.taf?Itemnumber=95563

Alobar

On Fri, Aug 21, 2009 at 1:51 PM, Wilkins<montemomma2002@...> wrote:

> I became aware of this through the silver list and think its important enough

to share.

> This is for research purposes only.

> «

> Make Your Own Liposomal Encapsulated Vitamin C

>

>

> From: Bradley

> Sent: Tuesday, August 11, 2009 12:20 PM

> To:

> Subject: CS>Liposomal Encapsulation Technology: Vit “C”

> In our recent researches evaluating this technology and, consequently, in

searching for possible “process” improvements/modifications which might

facilitate the “lay person” an opportunity for a DIY methodology achievable in a

home environment—we did achieve some notable progress.

> First, a brief summary of our exploratory activity. Our literature searches

revealed several companies actively exhibiting valid capability in this area

(LET).

> Typical, and demonstrably capable, is a company named MICROTEK.

Microteklabs.com

> Helpful information is available here.

> One fact became obvious, early on, to wit: The truly striking feature of LET

was a NATURALLY-occurring characteristic…… and not a man-made process, that was

driving this encapsulation process. That is, this process is a function of an

automatic, “natural tendency” of certain substances (e.g. phospholipids in this

case) to form tiny vacoules or

> bubbles—called liposomes—-when in a aqueous solution under certain conditions.

”

> The keystone activity is that these liposomes automatically fill themselves

with whatever aqueous solution they were in—-before they were formed. “This type

of bubble, called a membrane, forms a protective barrier around virtually every

cell in the human body.”

> Livon Labs has perfected a process which employs a high-pressure (1700 p.s.i.)

discharge system which directs a liquid stream against a forming plate. The high

impact forces the phospholipids (soy lecithin in this case) to form

liposomes—-so small they require an electrom microscope for viewing. This

technology does not create the LET activity….it just enhances it. In our

personal researches we have determined the key to exploiting the LET phenomenon

appeared to be Livon’s application of intense force in their mixing methodology.

> Enter the “enlightening” moment. Searching for a method of achieving liposomal

encapsulation, it occurred to us to explore ultrasonic stimulation as an option.

It worked…maybe not quite as well as Livon’s “high tech” brute force

approach…but about 70% as well. Plenty efficient for our purposes.

> Our vitamin “C” liposomal encapsulation protocol is as follows:

> Using a small (2 cup) Ultrasonic cleaner, (Item #03305, obtainable from Harbor

Freight @ about $30.00), we performed the following:

> 1. Dissolved 3 level tablespoons of soy lecithin in 1 cup of water (preferably

distilled).

> 2. Dissolved 1 level tablespoon of ascorbic acid powder (Vit. “C”) in 1/2 cup

> of water.

> 3. Poured both solutions together in the ultrasonic cleaner bowl and turned

the unit on. Using a plastic straw (leaving the top of the cleaner opened),

gently, slowly, stirred the contents. Note: The cleaner will, automatically,

self-stop about every 2 minutes. Just push ON button to continue. Repeat for a

total of 3 series (6 minutes). By that time the entire solution should be

blended into a cloudy, homogeneous,

> milk-like mixture. The LET solution is now formed.

> 4. This protocol furnishes about 12 grams (12000mg.) of vitamin C product. At

70% encapsulation efficiency, 8400 mg would be of the LET type. This solution

will keep, acceptably, at room temperature for 3 to 4 days. Refrigerated, it

will keep much longer.

> We use it so fast around our place…there isn’t enough left to be concerned

over storage. The “homogenizing effect” is so powerful that after 3 days at room

temperature, no precipitation or solution separation appears evident. This type

of sequestered vitamin “C” has demonstrated to be, at least 5 times more

effective (per volumetric measure) than any other form of orally-ingested

vitamin “c”….that we have tested.

> Additionally, it appears to be even more rapid in tissue-bed

availability—-than IV applications. An astounding revelation….to us. We estimate

the DIY researcher can produce the active LET portion of this solution for 15

cents per gram….as against about $1.00 per gram from commerci! al sources.

> It is my hope that this, limited, explanation of our activities in this area,

> is of some value to our do-it-yourself health-maintenance researchers. In any

event, this protocol has demonstrated to be n on-toxic and most helpful to OUR

RESEARCHES.

> Sincerely, Bradley.

>

> p.s. A larger, more powerful, ultrasonic cleaner is now available at Harbor

Freight. Item number 91593. 2+ liters, for about $60.00. Both units have

performed quite well for us. Almost as well as our $500.00 lead zirconate

titanate, research grade, unit.

>

>

>

>

>

> Wilkins

[Guest guest]

Here is the smaller capacity unit (1 pint):

http://www.harborfreight.com/cpi/ctaf/displayitem.taf?Itemnumber=3305

Very interesting, ! Thank you for posting this.

nah

>

> Looks like item number and price below is incorrect.

> http://www.harborfreight.com/cpi/ctaf/displayitem.taf?Itemnumber=95563

>

> Alobar

>

[Guest guest]

Just purchased this smaller cleaner from Harbor Freight, and also ascorbate acid

powder and lecithin from iHerb.com.

I doubt if anyone here will find this as funny as I do, but on iHerb, when you

put something in your cart, suggestions for additional purchases appear, based

on what other customers have ordered. So I put the Vit C in the cart, and up

pops lecithin. I think to myself, " hmm...imagine that! " So, of course, I put

the lecithin in the cart, and up pops Nutiva CO. " Huh??? Ok, which one of you

beat me to the punch? " LOL (Laughing is healthy.)

Anyway, I have a coupon code for this site, $5.00 off, good for first time

orders, as part of their rewards program. HOM016

Am looking forward to making the LET C! I crave C. I eat lemons even when I'm

not having margaritas. (Which I am currently not, just in case you thought so.)

Cheers!

nah

> >

> > Looks like item number and price below is incorrect.

> > http://www.harborfreight.com/cpi/ctaf/displayitem.taf?Itemnumber=95563

> >

> > Alobar

> >

>

[Guest guest]

I got a small one that easily fits the 1 1/2 cups from harbor freight last week

for 25.00 but it was on sale . It is usally 35 dollars.

Fortunately, I have a harbor frieght in the city I live in.

> > I became aware of this through the silver list and think its important

enough to share.

> > This is for research purposes only.

> > «

> > Make Your Own Liposomal Encapsulated Vitamin C

> >

> >

> > From: Bradley

> > Sent: Tuesday, August 11, 2009 12:20 PM

> > To:

> > Subject: CS>Liposomal Encapsulation Technology: Vit " C "

> > In our recent researches evaluating this technology and, consequently, in

searching for possible " process " improvements/modifications which might

facilitate the " lay person " an opportunity for a DIY methodology achievable in a

home environment—we did achieve some notable progress.

> > First, a brief summary of our exploratory activity. Our literature searches

revealed several companies actively exhibiting valid capability in this area

(LET).

> > Typical, and demonstrably capable, is a company named MICROTEK.

Microteklabs.com

> > Helpful information is available here.

> > One fact became obvious, early on, to wit: The truly striking feature of LET

was a NATURALLY-occurring characteristic…… and not a man-made process, that was

driving this encapsulation process. That is, this process is a function of an

automatic, " natural tendency " of certain substances (e.g. phospholipids in this

case) to form tiny vacoules or

> > bubbles—called liposomes—-when in a aqueous solution under certain

conditions. "

> > The keystone activity is that these liposomes automatically fill themselves

with whatever aqueous solution they were in—-before they were formed. " This type

of bubble, called a membrane, forms a protective barrier around virtually every

cell in the human body. "

> > Livon Labs has perfected a process which employs a high-pressure (1700

p.s.i.) discharge system which directs a liquid stream against a forming plate.

The high impact forces the phospholipids (soy lecithin in this case) to form

liposomes—-so small they require an electrom microscope for viewing. This

technology does not create the LET activity….it just enhances it. In our

personal researches we have determined the key to exploiting the LET phenomenon

appeared to be Livon's application of intense force in their mixing methodology.

> > Enter the " enlightening " moment. Searching for a method of achieving

liposomal encapsulation, it occurred to us to explore ultrasonic stimulation as

an option. It worked…maybe not quite as well as Livon's " high tech " brute force

approach…but about 70% as well. Plenty efficient for our purposes.

> > Our vitamin " C " liposomal encapsulation protocol is as follows:

> > Using a small (2 cup) Ultrasonic cleaner, (Item #03305, obtainable from

Harbor Freight @ about $30.00), we performed the following:

> > 1. Dissolved 3 level tablespoons of soy lecithin in 1 cup of water

(preferably distilled).

> > 2. Dissolved 1 level tablespoon of ascorbic acid powder (Vit. " C " ) in 1/2

cup

> > of water.

> > 3. Poured both solutions together in the ultrasonic cleaner bowl and turned

the unit on. Using a plastic straw (leaving the top of the cleaner opened),

gently, slowly, stirred the contents. Note: The cleaner will, automatically,

self-stop about every 2 minutes. Just push ON button to continue. Repeat for a

total of 3 series (6 minutes). By that time the entire solution should be

blended into a cloudy, homogeneous,

> > milk-like mixture. The LET solution is now formed.

> > 4. This protocol furnishes about 12 grams (12000mg.) of vitamin C product.

At 70% encapsulation efficiency, 8400 mg would be of the LET type. This solution

will keep, acceptably, at room temperature for 3 to 4 days. Refrigerated, it

will keep much longer.

> > We use it so fast around our place…there isn't enough left to be concerned

over storage. The " homogenizing effect " is so powerful that after 3 days at room

temperature, no precipitation or solution separation appears evident. This type

of sequestered vitamin " C " has demonstrated to be, at least 5 times more

effective (per volumetric measure) than any other form of orally-ingested

vitamin " c " ….that we have tested.

> > Additionally, it appears to be even more rapid in tissue-bed

availability—-than IV applications. An astounding revelation….to us. We estimate

the DIY researcher can produce the active LET portion of this solution for 15

cents per gram….as against about $1.00 per gram from commerci! al sources.

> > It is my hope that this, limited, explanation of our activities in this

area,

> > is of some value to our do-it-yourself health-maintenance researchers. In

any event, this protocol has demonstrated to be n on-toxic and most helpful to

OUR RESEARCHES.

> > Sincerely, Bradley.

> >

> > p.s. A larger, more powerful, ultrasonic cleaner is now available at Harbor

Freight. Item number 91593. 2+ liters, for about $60.00. Both units have

performed quite well for us. Almost as well as our $500.00 lead zirconate

titanate, research grade, unit.

> >

> >

> >

> >

> >

> > Wilkins

>

[Guest guest]

Do you know if he is saying to use dry lecithin, or liquid? I just tried the

liquid; ran it 10 times and the lecithin is still clumped, although some did

dissolve, and I have cloudy water.  I also tried to heat some in water, no

luck.

 

From: montemomma2002 <montemomma2002@...>

Subject: Re: Make Your Own Liposomal Encapsulated

Vitamin C

Coconut Oil

Date: Sunday, August 23, 2009, 3:21 PM

I got a small one that easily fits the 1 1/2 cups from harbor freight last week

for 25.00 but it was on sale . It is usally 35 dollars.

Fortunately, I have a harbor frieght in the city I live in.

>

> Looks like item number and price below is incorrect.

> http://www.harborfr eight.com/ cpi/ctaf/ displayitem. taf?Itemnumber= 95563

>

> Alobar

[snipped by moderator Carol]

[Guest guest]

, the scientist,used the powdered form , but the liquid lecithin should

work . Im not sure of the measurements though if the liquid is used. And yes I

got a cloudy liquid with the soupy yellow stuff on the bottom. Im not sure which

part of that has the lipo c . But remember only about 70 % becomes lipo coated

the rest stays as normal c . Thats ok too . I also run my sonic cleaner about 5

times instead of 3 .Thats just me though I want to make sure it gets good and

mixed.

I use warm water to disolve the lecithin to put in the machine and I let it soak

for about ten minutes as I disolve it . then put it in the ultrasonic cleaner

with the c and turn it on. It couldnt be simpler

I put it in a jar shake it before pouring out and use an ounce to mix in my

smoothy or orange juice. 1 oz will have about 1 gram of LET vitamin C less the

30% that doesnt encapsulate so about 700 mg of LET.

It tastes bad . not horrible but bad. however even my kids will drink it

diguised in a smoothy. With all the hullabaloo about flu and vaccines I think

its important to build our immune systems before anything comes our way.... We

will not be taking the vaccine and becoming guinea pigs for a drug company!

IN NC

> >

> > Looks like item number and price below is incorrect.

> > http://www.harborfr eight.com/ cpi/ctaf/ displayitem. taf?Itemnumber= 95563

> >

> > Alobar

>

> [snipped by moderator Carol]

>

[Guest guest]

I think , but am not sure that the lecithin has the vitamin C encapsulated

inside it so clumping is fine. Did you stir it with a straw while it was in the

machine?

IN NC

> >

> > Looks like item number and price below is incorrect.

> > http://www.harborfr eight.com/ cpi/ctaf/ displayitem. taf?Itemnumber= 95563

> >

> > Alobar

>

> [snipped by moderator Carol]

>

[Guest guest]

I switched to the lewislabs brand of dry lecithin; it worked better; seemed to

dissolve and break down.  -still has clumps, but they're mushy, and less of

them. . It also has a good taste. I also wonder if sodium ascorbate would be

better absorbed, because it dissolves faster.

  

From: montemomma2002 <montemomma2002@...>

Subject: Re: Make Your Own Liposomal Encapsulated

Vitamin C

Coconut Oil

Date: Sunday, August 23, 2009, 6:10 PM

 

I think , but am not sure that the lecithin has the vitamin C encapsulated

inside it so clumping is fine. Did you stir it with a straw while it was in the

machine?

IN NC

> >

> > Looks like item number and price below is incorrect.

> > http://www.harborfr eight.com/ cpi/ctaf/ displayitem. taf?Itemnumber= 95563

> >

> > Alobar

>

> [snipped by moderator Carol]

>

[Guest guest]

There's a long thread at the Vitamin C Foundation forums about making homemade

Liposomal C. The author of the method did say Lecithin granules. I copied some

of what I thought was helpful info from the thread. Mr. Bradley is a bit wordy,

but answers many questions. Thanks to for telling us about this

interesting topic.

From Bradley, author of homemade Lipo C.

" Livon Labs has perfected a process which employs a high-pressure (1700 p.s.i.)

discharge system which directs a liquid stream against a forming plate. The high

impact forces the phospholipids (soy lecithin in this case) to form

liposomes—-so small they require an electrom microscope for viewing. This

technology does not create the LET activity….it just enhances it. In our

personal researches we have determined the key to exploiting the LET phenomenon

appeared to be Livon's application of intense force in their mixing methodology.

Enter the " enlightening " moment. Searching for a method of achieving liposomal

encapsulation, it occurred to us to explore ultrasonic stimulation as an option.

It worked…maybe not quite as well as Livon's " high tech " brute force

approach…but about 70% as well. Plenty efficient for our purposes.

Our vitamin " C " liposomal encapsulation protocol is as follows:

Using a small (2 cup) Ultrasonic cleaner, (Item #03305, obtainable from Harbor

Freight @ about $30.00), we performed the following:

1. Dissolved 3 level tablespoons of soy lecithin in 1 cup of water (preferably

distilled).

2. Dissolved 1 level tablespoon of ascorbic acid powder (Vit. " C " ) in 1/2 cup of

water.

3. Poured both solutions together in the ultrasonic cleaner bowl and turned the

unit on. Using a plastic straw (leaving the top of the cleaner opened), gently,

slowly, stirred the contents. Note: The cleaner will, automatically, self-stop

about every 2 minutes. Just push ON button to continue. Repeat for a total of 3

series (6 minutes). By that time the entire solution should be blended into a

cloudy, homogeneous, milk-like mixture. The LET solution is now formed.

4. This protocol furnishes about 12 grams (12000mg.) of vitamin C product. At

70% encapsulation efficiency, 8400 mg would be of the LET type. This solution

will keep, acceptably, at room temperature for 3 to 4 days. Refrigerated, it

will keep much longer.

We use it so fast around our place…there isn't enough left to be concerned over

storage. The " homogenizing effect " is so powerful that after 3 days at room

temperature, no precipitation or solution separation appears evident. This type

of sequestered vitamin " C " has demonstrated to be, at least 5 times more

effective (per volumetric measure) than any other form of orally-ingested

vitamin " c " ….that we have tested.

Additionally, it appears to be even more rapid in tissue-bed availability—-than

IV applications. An astounding revelation….to us. We estimate the DIY researcher

can produce the active LET portion of this solution for .15 cents per gram….as

against about $1.00 per gram from commercial sources.

It is my hope that this, limited, explanation of our activities in this area, is

of some value to our DIY health-maintenance researchers. In any event, this

protocol has demonstrated to be n on-toxic and most helpful to OUR RESEARCHES.

Sincerely, Bradley

p.s. A larger, more powerful, ultrasonic cleaner is now available at Harbor

Freight. Item number 91593. 2+ liters, for about $60.00. Both units have

performed quite well for us. Almost as well as our $500.00 lead zirconate

titanate, research grade, unit.

TESTING THE LIPO SOLUTION

Although not scientifically rigorous, I offer a simple test which will yield the

DIY researcher some element of confidence that they do, in fact, have a useful

measure of liposomal encapsulate.

First, pour about 4 ounces of your finished Vitamin C encapsulate into a

cylindrical, 12 ounce water glass. Next, place 1/4 teaspoon of sodium

bicarbonate into about 1 ounce of distilled water and stir for 3 to 5 seconds.

Next, pour the sodium bicarbonate solution into the Vitamin C mixture and stir

gently for several seconds.

Note: If the foam/bubble line which forms on top is 1/2 inch or less—in

height—you have about a 50% encapsulation efficiency. If the foam/bubble line is

3/8 of one inch…or less, you have about a 60% efficiency.

If the foam/bubble line is 1/8 inch or less, you have about 75% efficiency. If

the foam/bubble line is just a trace…..you should major in chemistry.

The percentages given above, represent the amount of the total Vitamin C

component incorporated during the encapsulation process…..that was actually

encapsulated. The less encapsulation….the greater the foaming.

What is, actually, occurring in this test is that the ascorbic acid fraction is

being transformed into the sodium ascorbate form of vitamin C. This test does

not negatively affect the usefulness of the solution you have tested…..as the

isolated Vitamin C component is not adversely affecting the encapsulate (which

is being protected by the lecithin bubble-covering.) Actually, the sodium

ascorbate form of vitamin C is greater than an order-of-magnitude more soluble

for tissue incorporation……than is the ascorbic acid form.

In any event this simple test should serve to raise the level of confidence in

the DIY researcher…. that they do—in fact—have a useful measure of encapsulated

vitamin C.

Sincerely, Bradley

SEPARATION OF PRODUCT

My apologies; I neglected to outline the attendant, probable, variations in the

protocol. What I SHOULD have said in my original post is " The visible, obviously

homogenized, portion of the solution " , whenever I made the comment about the

stability of the completed, resultant, material.

I believe you will gain a little better knowledge of the results you achieved,

after reading my most recent comment on an inquiry by Sheila.

Bottom line -your result was perfectly normal. Interestingly, the meniscus may

present at the top…or the bottom…..or not at all. Usually if the initial

material combination has not run long enough to incorporate a majority of the

lecithin (or there is simply too much lecithin for the available ascorbic acid

fraction…..the meniscus will form on the top of the sample within a few minutes

after stopping the US agitation.

If your procedure has run acceptably well and-long enough to homogenize well,

any meniscus formation will, generally, present on the BOTTOM after overnight

storage with or without refrigeration.

In any event, you are doing fine. If you do not want to consume the isolated

lecithin fraction you are observing, just decant the homogenized liposome

solution and dispose of the isolated lecithin fraction.

p.s. One just needs to continue to experiment " around-the-edges " of this

protocol, in order to achieve optimum results. Do not be reluctant to do such,

this IS NOT ROCKET SCIENCE …just common sense.

Sincerely, Bradley

LECITHIN AND MIXING

First, soy lecithin is a slow incorporator, when introduced into aqueous

mediums….sometimes. Especially, when there is a high lecithin *granule*

population ratio-relative to the total water volume. The general reaction is

that a major percentage of the lecithin blends readily with the the water

medium, but there will remain a definitive lecithin component which floats on

the surface and exhibits a somewhat " gelatinous " appearance (this is quite

natural, based upon the native characteristics of the substances involved). Do

not fret over encountering such circumstances……they will not compromise the

basic effectiveness of your protocol.

However, it is of some import(ance) to understand that the speed, and

completeness, of the incorporation of the granular lecithin—into the aqueous

medium, is affected by a number of conditions such as the total amount of

lecithin versus the total volume of water; the temperature of the water-based

solution and the strength of any other substance being incorporated into the

parent solution-from very weak, to saturated (none of which are seriously

compromising).

Under the best of conditions, even after ultrasonic mixing for 8 to 9

minutes….there is, often, a thin meniscus (a distinct separation between two or

more liquids in the same container). [Example: a thin layer of oil lying on top

of water.] In the liposome generation methodology we are discussing, the

visible, gelatinous, portion of the meniscus is principally made up of

unincorporated lecithin. It IS NOT a problem, in fact the lecithin component has

useful, cardiovascular, health-support effects-beyond those being discussed

here.

Either (or both) of two measures may be executed to reduce the volume of

unincorporated lecithin you may be encountering. First, increasing the volume of

the total water fraction, or secondly, raising the temperature of the total

parent solution and extending the time of US reaction exposure.

One reason for the condition you are encountering is that the closer one gets to

achieving a saturated solution of lecithin….the more resistant the process

becomes to accepting more granular lecithin into that solution until the point

is reached where no further material will incorporate hence, THE SATURATION

POINT IS EXPERIENCED.

In my brief, original post, I did not discuss the nuances of speed, degree or

completeness of dissolution of the lecithin—-or for that matter— the ascorbic

acid fraction. Neither did I outline a number of other considerations; such as

the effects of varying the volume of water versus the ratios of the solution

components ..or the total water volume versus the protocol components primarily,

because such elaborations would not serve usefulness/effectivity for the

nontechnical.

DIY person. I simply outlined a SAFE, mid-spectrum, protocol allowing the

average lay-person to achieve a measure of acceptable results for home

experimental research.

My personal bias is that it is better to have a small, uncombined, lecithin

fraction presenting as a meniscus…..than to strive toward what I perceive to be

a cosmetic achievement-of small consequence..by means of diluting the total

solution. In any event the excess lecithin is a positive addition..it is just

not active in the liposome process until some parameter changes that avails it

the opportunity participate in the encapsulation process.

My final comment on this subject: If it is of paramount importance to one,

regardless of reason. by just increasing the water volume and reactivating the

US Cleaner for several minutes….the remaining lecithin will (in almost all

cases) go into the emulsified solution. However, bear in mind, you have diluted

the entire solution by an equivalent strength with NO increase in total vitamin

C component.

Whole Thread at Vitamin C Foundation Forums - " Homemade Lypo C "

http://snipurl.com/qspnh

If someone would rather buy it retail, letstalkhealth.com has these prices. If

Liposomal is 7-10 times more effective than regular C, then the prices aren't

bad. Dr. Kurt W. Donsbach formulates all the products at LTH. The Vit C

Foundation is testing these products and if OK, will start selling them.

90 capsules - 67,000mg (90 days/670 mg.) $22.40 + shipping

8 oz liquid - 48,000mg (71 days/670 mg.) $34.30 + $6 extra shipping

http://www.letstalkhealth.com/Liposomal-s/32.htm

[Guest guest]

I like the taste of Labs lecithin, but I have a problem with

it. Here in New Orleans, it is very humid. The lecithin tends to

clump from moisture into a cement like aggregate. This does not

dissolve in water hardly at all.

When I get an ultrasonic cleaner, I may try mixing lecithin and water

with the ultrasonic cleaner before I add the vitamin C solution, just

to get the lecithin to dissolve before I try making the Liposomal

Encapsulated C.

Alobar

On Sun, Aug 23, 2009 at 7:19 PM, arthur rambo<alquitit@...> wrote:

> I switched to the lewislabs brand of dry lecithin; it worked better; seemed to

dissolve and break down.  -still has clumps, but they're mushy, and less of

them. . It also has a good taste. I also wonder if sodium ascorbate would be

better absorbed, because it dissolves faster.

>

>

[Guest guest]

I made a mistake in the amounts in the capsules and liquid sold by

Letstalkhealth. Should be 750 mg, not 670mg.

90 capsules - 67,500mg (90 days/750 mg.) $22.40 + shipping

8 oz liquid - 48,000mg (64 days/750 mg.) $34.30 + $6 extra shipping

http://www.letstalkhealth.com/Liposomal-s/32.htm

[Guest guest]

Acording to Daddybob, Bradley is in his 80s and very busy with research

and only posts innfrequently at the silverlist usually with very important

info.So that is where you need to go if you want to communicate with him and it

might be slow to get answers.

> > There's a long thread at the Vitamin C Foundation forums about making

homemade Liposomal C. The author of the method did say Lecithin granules. I

copied some of what I thought was helpful info from the thread. Mr. Bradley is a

bit wordy, but answers many questions. Thanks to for telling us about this

interesting topic.

> >

> >

> > From Bradley, author of homemade Lipo C.

> >

> > " Livon Labs has perfected a process which employs a high-pressure (1700

p.s.i.) discharge system which directs a liquid stream against a forming plate.

The high impact forces the phospholipids (soy lecithin in this case) to form

liposomes—-so small they require an electrom microscope for viewing. This

technology does not create the LET activity….it just enhances it. In our

personal researches we have determined the key to exploiting the LET phenomenon

appeared to be Livon's application of intense force in their mixing methodology.

> >

> > Enter the " enlightening " moment. Searching for a method of achieving

liposomal encapsulation, it occurred to us to explore ultrasonic stimulation as

an option. It worked…maybe not quite as well as Livon's " high tech " brute force

approach…but about 70% as well. Plenty efficient for our purposes.

> >

> > Our vitamin " C " liposomal encapsulation protocol is as follows:

> >

> > Using a small (2 cup) Ultrasonic cleaner, (Item #03305, obtainable from

Harbor Freight @ about $30.00), we performed the following:

> > 1. Dissolved 3 level tablespoons of soy lecithin in 1 cup of water

(preferably distilled).

> >

> > 2. Dissolved 1 level tablespoon of ascorbic acid powder (Vit. " C " ) in 1/2

cup of water.

> >

> > 3. Poured both solutions together in the ultrasonic cleaner bowl and turned

the unit on. Using a plastic straw (leaving the top of the cleaner opened),

gently, slowly, stirred the contents. Note: The cleaner will, automatically,

self-stop about every 2 minutes. Just push ON button to continue. Repeat for a

total of 3 series (6 minutes). By that time the entire solution should be

blended into a cloudy, homogeneous, milk-like mixture. The LET solution is now

formed.

> >

> > 4. This protocol furnishes about 12 grams (12000mg.) of vitamin C product.

At 70% encapsulation efficiency, 8400 mg would be of the LET type. This solution

will keep, acceptably, at room temperature for 3 to 4 days. Refrigerated, it

will keep much longer.

> >

> > We use it so fast around our place…there isn't enough left to be concerned

over storage. The " homogenizing effect " is so powerful that after 3 days at room

temperature, no precipitation or solution separation appears evident. This type

of sequestered vitamin " C " has demonstrated to be, at least 5 times more

effective (per volumetric measure) than any other form of orally-ingested

vitamin " c " ….that we have tested.

> >

> > Additionally, it appears to be even more rapid in tissue-bed

availability—-than IV applications. An astounding revelation….to us. We estimate

the DIY researcher can produce the active LET portion of this solution for .15

cents per gram….as against about $1.00 per gram from commercial sources.

> >

> > It is my hope that this, limited, explanation of our activities in this

area, is of some value to our DIY health-maintenance researchers. In any event,

this protocol has demonstrated to be n on-toxic and most helpful to OUR

RESEARCHES.

> >

> > Sincerely, Bradley

> >

> > p.s. A larger, more powerful, ultrasonic cleaner is now available at Harbor

Freight. Item number 91593. 2+ liters, for about $60.00. Both units have

performed quite well for us. Almost as well as our $500.00 lead zirconate

titanate, research grade, unit.

> >

> >

> > TESTING THE LIPO SOLUTION

> >

> > Although not scientifically rigorous, I offer a simple test which will yield

the DIY researcher some element of confidence that they do, in fact, have a

useful measure of liposomal encapsulate.

> >

> > First, pour about 4 ounces of your finished Vitamin C encapsulate into a

cylindrical, 12 ounce water glass. Next, place 1/4 teaspoon of sodium

bicarbonate into about 1 ounce of distilled water and stir for 3 to 5 seconds.

Next, pour the sodium bicarbonate solution into the Vitamin C mixture and stir

gently for several seconds.

> >

> > Note: If the foam/bubble line which forms on top is 1/2 inch or less—in

height—you have about a 50% encapsulation efficiency. If the foam/bubble line is

3/8 of one inch…or less, you have about a 60% efficiency.

> >

> > If the foam/bubble line is 1/8 inch or less, you have about 75% efficiency.

If the foam/bubble line is just a trace…..you should major in chemistry.

> >

> > The percentages given above, represent the amount of the total Vitamin C

component incorporated during the encapsulation process…..that was actually

encapsulated. The less encapsulation….the greater the foaming.

> >

> > What is, actually, occurring in this test is that the ascorbic acid fraction

is being transformed into the sodium ascorbate form of vitamin C. This test does

not negatively affect the usefulness of the solution you have tested…..as the

isolated Vitamin C component is not adversely affecting the encapsulate (which

is being protected by the lecithin bubble-covering.) Actually, the sodium

ascorbate form of vitamin C is greater than an order-of-magnitude more soluble

for tissue incorporation……than is the ascorbic acid form.

> >

> > In any event this simple test should serve to raise the level of confidence

in the DIY researcher…. that they do—in fact—have a useful measure of

encapsulated vitamin C.

> >

> > Sincerely, Bradley

> >

> > SEPARATION OF PRODUCT

> >

> > My apologies; I neglected to outline the attendant, probable, variations in

the protocol. What I SHOULD have said in my original post is " The visible,

obviously homogenized, portion of the solution " , whenever I made the comment

about the stability of the completed, resultant, material.

> >

> > I believe you will gain a little better knowledge of the results you

achieved, after reading my most recent comment on an inquiry by Sheila.

> >

> > Bottom line -your result was perfectly normal. Interestingly, the meniscus

may present at the top…or the bottom…..or not at all. Usually if the initial

material combination has not run long enough to incorporate a majority of the

lecithin (or there is simply too much lecithin for the available ascorbic acid

fraction…..the meniscus will form on the top of the sample within a few minutes

after stopping the US agitation.

> >

> > If your procedure has run acceptably well and-long enough to homogenize

well, any meniscus formation will, generally, present on the BOTTOM after

overnight storage with or without refrigeration.

> >

> > In any event, you are doing fine. If you do not want to consume the isolated

lecithin fraction you are observing, just decant the homogenized liposome

solution and dispose of the isolated lecithin fraction.

> >

> > p.s. One just needs to continue to experiment " around-the-edges " of this

protocol, in order to achieve optimum results. Do not be reluctant to do such,

this IS NOT ROCKET SCIENCE …just common sense.

> >

> > Sincerely, Bradley

> >

> > LECITHIN AND MIXING

> >

> > First, soy lecithin is a slow incorporator, when introduced into aqueous

mediums….sometimes. Especially, when there is a high lecithin *granule*

population ratio-relative to the total water volume. The general reaction is

that a major percentage of the lecithin blends readily with the the water

medium, but there will remain a definitive lecithin component which floats on

the surface and exhibits a somewhat " gelatinous " appearance (this is quite

natural, based upon the native characteristics of the substances involved). Do

not fret over encountering such circumstances……they will not compromise the

basic effectiveness of your protocol.

> >

> > However, it is of some import(ance) to understand that the speed, and

completeness, of the incorporation of the granular lecithin—into the aqueous

medium, is affected by a number of conditions such as the total amount of

lecithin versus the total volume of water; the temperature of the water-based

solution and the strength of any other substance being incorporated into the

parent solution-from very weak, to saturated (none of which are seriously

compromising).

> >

> > Under the best of conditions, even after ultrasonic mixing for 8 to 9

minutes….there is, often, a thin meniscus (a distinct separation between two or

more liquids in the same container). [Example: a thin layer of oil lying on top

of water.] In the liposome generation methodology we are discussing, the

visible, gelatinous, portion of the meniscus is principally made up of

unincorporated lecithin. It IS NOT a problem, in fact the lecithin component has

useful, cardiovascular, health-support effects-beyond those being discussed

here.

> >

> > Either (or both) of two measures may be executed to reduce the volume of

unincorporated lecithin you may be encountering. First, increasing the volume of

the total water fraction, or secondly, raising the temperature of the total

parent solution and extending the time of US reaction exposure.

> >

> > One reason for the condition you are encountering is that the closer one

gets to achieving a saturated solution of lecithin….the more resistant the

process becomes to accepting more granular lecithin into that solution until the

point is reached where no further material will incorporate hence, THE

SATURATION POINT IS EXPERIENCED.

> >

> > In my brief, original post, I did not discuss the nuances of speed, degree

or completeness of dissolution of the lecithin—-or for that matter— the ascorbic

acid fraction. Neither did I outline a number of other considerations; such as

the effects of varying the volume of water versus the ratios of the solution

components ..or the total water volume versus the protocol components primarily,

because such elaborations would not serve usefulness/effectivity for the

nontechnical.

> >

> > DIY person. I simply outlined a SAFE, mid-spectrum, protocol allowing the

average lay-person to achieve a measure of acceptable results for home

experimental research.

> >

> > My personal bias is that it is better to have a small, uncombined, lecithin

fraction presenting as a meniscus…..than to strive toward what I perceive to be

a cosmetic achievement-of small consequence..by means of diluting the total

solution. In any event the excess lecithin is a positive addition..it is just

not active in the liposome process until some parameter changes that avails it

the opportunity participate in the encapsulation process.

> >

> > My final comment on this subject: If it is of paramount importance to one,

regardless of reason. by just increasing the water volume and reactivating the

US Cleaner for several minutes….the remaining lecithin will (in almost all

cases) go into the emulsified solution. However, bear in mind, you have diluted

the entire solution by an equivalent strength with NO increase in total vitamin

C component.

> >

> >

> > Whole Thread at Vitamin C Foundation Forums - " Homemade Lypo C "

> > http://snipurl.com/qspnh

> >

> >

> > If someone would rather buy it retail, letstalkhealth.com has these prices.

If Liposomal is 7-10 times more effective than regular C, then the prices aren't

bad. Dr. Kurt W. Donsbach formulates all the products at LTH. The Vit C

Foundation is testing these products and if OK, will start selling them.

> >

> >

> > 90 capsules - 67,000mg (90 days/670 mg.) $22.40 + shipping

> > 8 oz liquid - 48,000mg (71 days/670 mg.) $34.30 + $6 extra shipping

> > http://www.letstalkhealth.com/Liposomal-s/32.htm

> >

> >

> >

> >

> >

>