Guest guest Posted July 17, 2007 Report Share Posted July 17, 2007 Hi, I am curious about some past emails discussing the deletion of the FoxL2 Gene. I didn't know this was possible. A few years ago when we visited Dr. Collin in London he mentioned that they were in the process of doing so. Does anyone have insight on this and the effects it has on the girls with regard to being able to still have children? Thank you, Gwyneth's Mom, PamGet a sneak peek of the all-new AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 Hi Pam I am not sure what you are asking... Do you mean if a person is born with the gene deleted, which from what I understand, does happen. Or do you mean purposely " deleting " the affected gene? From what I understand, those born with a deleted gene, can have more developmental issues than the symptoms of BPES (narrow eyes openings, ptosis, inverted epicanthal fold). > > Hi, I am curious about some past emails discussing the deletion of the FoxL2 > Gene. I didn't know this was possible. A few years ago when we visited Dr. > Collin in London he mentioned that they were in the process of doing so. > Does anyone have insight on this and the effects it has on the girls with > regard to being able to still have children? > > Thank you, > Gwyneth's Mom, Pam > > > > ************************************** Get a sneak peek of the all- new AOL at > http://discover.aol.com/memed/aolcom30tour > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2007 Report Share Posted July 19, 2007 Therese, I hope to find out more too. I am just referring to an email I read from one of the other parents. It is so great to have this group. I cannot tell you how much comfort it has given me. Let us know how your meeting goes with Dr. Collin. Best, PamGet a sneak peek of the all-new AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2007 Report Share Posted July 19, 2007 Hi Pam My name is Therese and I've just read your email and was struck by the possibility of being able to delete the fox2l gene. I know so little about it but will be seeing mr Collin in September so could find out more about it. We have a little girl called Esme who is nearly 3yrs we dont know what type of Bleph she has and at this point are just praying that she will be able to have children in the future if she wants to. Best wishes Therese Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 26, 2007 Report Share Posted July 26, 2007 Hi Pam, I'm sorry! I can't remember if I replied already or not, I haven't had a chance to check my mail for ages, so apologies if this is a duplicate email. I started a thread a while back about Gene Deletion. My 14month old daughter got her genetic test results back a few months ago, and the geneticist told us that the results said that she had total deletion of the FOXL2 Gene. He said that this confirmed she has BPES and that she will most certainly have fertility issues. He said that POF (premature ovarian failure) was not the 'Given' prognosis in all cases - as it depends, case by case. In my daughters case - where the gene is totally deleted, he said that it was likely she would not even produce eggs! In partial gene deletion, POF is more common. We were very upset by this news, as you can imagine... But we are trying to research it more and find out what options exist. I personally believe that every case is different, like us all! Kind regards, blepharophimosis Gene Deletion Hi, I am curious about some past emails discussing the deletion of the FoxL2 Gene. I didn't know this was possible. A few years ago when we visited Dr. Collin in London he mentioned that they were in the process of doing so. Does anyone have insight on this and the effects it has on the girls with regard to being able to still have children? Thank you, Gwyneth's Mom, Pam Get a sneak peek of the all-new AOL.com. Send instant messages to your online friends http://uk.messenger. Quote Link to comment Share on other sites More sharing options...
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