Re: Tasigna and plurel effusion

February 16, 2009

Hi Barb, when I had the problem, I found it hard to breathe, and had pain in my

right upper back and side. I actually called 911 because I thought i was having

a heart attack. I told them and I told Er pleural effusion was a side effect

of the drug Sprycel. they dx me with pneumonia. When I went to see my GP, I

told him the same thing, and he said, no, I had pneumonia. I had no other

symptoms of it, and had had it before, and kept telling them it could be pe. I

eventually had to have a thoracentesis done, removing 1 1/2 liters fluid. Dr.

Talpaz said i most likely never had pneumonia, it was pe all the time. Very

uncomfortable, and the pain lasted a long time. Of course, that was the end of

sprycel, which was too bad, i really liked that drug.

I hope you are feeling better soon, but if the pe did not show up in the xray,

you most likely don't have it, I'm no expert, but it should show up.

Take care, blessings, Bobby

a (Bobby) Doyle Brecksville, Ohio, USA DX 05/1995 02/2000 - Gleevec

Trial/OHSU 06/2002 - Gleevec/Trisenox Trial/OHSU 06/2003 - Gleevec/Zarnestra

Trial/OHSU 04/2004 - Sprycel Trial/MDACC, CCR in 10 months #840 - Zavie's

Zero Club 09/2006 - out of CCR 04/29/08 - XL228 Trial/ U.of Michigan

06/02/08 - CCR ( in 4 weeks)

02/13/09 - XL trial ended due to side effects

From: Barb Stanley <barbarastanley@...>

Subject: [ ] Tasigna and plurel effusion

Date: Monday, February 16, 2009, 6:40 PM

Hello all

It has been a while since I posted. Many things happening, some good

and some not so pleasant. Suffice it to say, life happens and we just

have learned to roll with the flow. My thoughts have been about my

kids, their needs and safety lately and not necessarily CML. Must

say, it was kind of nice not to focus on CML for a while.

I have not posted in a while - and I apologize. I read and think,

pray for some of you and think fondly of you as my friends. Lottie,

it is so good to see you back on line and running foot races around

us all. I have kept up with your posts.

I have a question. I had a check up just two weeks ago. Had the

normal 5 vials of blood drawn, the usual tests and all came back

good. I am still PCRU on 400 mg of tasigna. Side effects are there

but not as bad as gleevec. I am incredibly grateful.

I have had some back pain, not in the bone or spine but in the lower

lobe of what I would call my left lung space. It felt much like a

pulled muscle - and if I would roll on it a certain way, or bend a

certain way, the pain was excruciating. The oncologist thought

maybe plurel effusion. I thought symptoms of that would occur in the

front of my chest and not in my back. They took chest XRays and they

showed nothing - but of course, it cleared up about a week before the

X-Ray. My question to the group: has anyone had it? What did it

feel like?

Any thoughts, wisdom or advice from anyone would be appreciated.

I will try to keep in touch better.

Love

Barb

February 18, 2009

Hi Barb,

You are living life and that's what's important. Please know that I are here for

you need if you need me.

As far as PE, I am not familiar with it. I have a friend who is fighting breast

cancer and I think she may have it. Could it happen with other chemotherapies

too?

Whatever it is, I hope someone on the list can guide you in the right

direction. You are your best doctor, if you need more answers seek a second

opinion. You deserve to be better without pain.

I'm praying for you that it is not PE or anything significant.

God Bless, Jackie S.

From: Barb Stanley <barbarastanley@...>

Subject: [ ] Tasigna and plurel effusion

Date: Monday, February 16, 2009, 5:40 PM