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Hi I read the site always but don't often post.  I had a bonemarrow transplant

for cml in 1993, I relapsed in 2004 and have been taking glivec since.  My

initial response to glivec was slow so it was increased from 400 to 600 mg per

day.  I have also had donor lymphacite infusions to see if I can once again

reach zero ph.  My pcr has been steadily dropping to hover around zero, but not

conclusively all gone.  The last 3 tests were equivocal, 0.00 and equivocal

again.  According to the dictionary, equivocal means uncertain or suspicious. 

My doctor has suggested that it may be a good time to try another drug to see if

I can reach complete remission again.  He is suggesting I think about notalib (

I think that is the spelling)  with the hope this will remove the lingering cml

cells.  Does any one on this site take this drug and what are the side

effects.  According to my doctor, the this drug is far better tolerated than

glivec and is far more

potent.  I would be interested to hear what others say about the drug, and I

guess I am wondering what I should do, any thoughts would be greatly

appreciated.

Judy T

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