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Drs. Neil Shah & Feldman

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Drs. Neil Shah and Feldman both talk about leukemia and Gleevec at the

American Society of Hematology (ASH) annual meeting. There is also a podcast

available at this same website, but my speakers are out so I read the transcript

posted from LLS and pasted some of the quotes. In the media, it is called a

teaser, to get your attention. I think you will be interested in reading or

listening to all of it, this is only a small part.

" Dr. Shah reported that if CML loses a response to Gleevec (relapses) it is most

likely due to 1 of 90 identified molecular mutations (changes). Sometimes a safe

dose of Gleevec is not able to stop cells from overexpressing (making too much)

Bcr-Abl, a cancer-causing protein. " He also praised patients with CML for

their participation in clinical trials.

Dr, Feldman said, " Gleevec is great, but the big question facing us now is, can

we do better? "

Very interesting transcript. More at t his website.

http://www.leukemia-lymphoma.org/graphics/National/EI2547A6T6CMLNLVol18.pdf

FYI,

Lottie

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